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Panama City

$522+ Cheap flights from Harrisburg (MDT) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
jul. 5 — jul. 121
sáb. 7/5
sáb. 7/12
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 30, 2025.

Round-trip from

$522
(Delta)

Popular in

February

Cheapest in

August

Average price

$699
From Harrisburg to Panama City Tocumen Intl
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Highest demand for flights based on searches. 1% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Harrisburg to Panama City

Cheapest flights from Harrisburg to Panama City
Explore the most affordable flight options available from Harrisburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 30, 2025.

This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/125:00 pmMDT - PTY
2 stops20h 47mDelta
jue. 10/162:12 pmPTY - MDT
2 stops20h 45mDelta
Deal found 6/29$522
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:27 pmMDT - PTY
2 stops20h 58mAmerican Airlines
lun. 12/82:45 pmPTY - MDT
2 stops18h 15mAmerican Airlines
Deal found 6/27$564
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:30 amMDT - PTY
2 stops13h 07mUnited Airlines
mar. 8/1910:00 amPTY - MDT
2 stops26h 48mUnited Airlines
Deal found 6/28$629

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 30, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama City that are best for you.

Fly from

Harrisburg

Fly to

Panama City

Route

Depart

Return

Price

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

dom. 10/12

5:00 pm-12:47 pm

2 stops20h 47m

Panama City Tocumen Intl

jue. 10/16

2:12 pm-11:57 am

2 stops20h 45m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

jue. 12/4

6:27 pm-3:25 pm

2 stops20h 58m

Panama City Tocumen Intl

lun. 12/8

2:45 pm-9:00 am

2 stops18h 15m

$564

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

mar. 8/12

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

mar. 8/19

10:00 am-1:48 pm

2 stops26h 48m

$629

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Best time to book a flight from Harrisburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama City

What is the cheapest month to book a flight from Harrisburg to Panama City?

Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $478). Flying from Harrisburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to PTY?

Find hourly flight availability from Harrisburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Panama City as you normally would.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated junio 30, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,969 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,969 reviews
Delta
8.0
Very good
7,969 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,852 reviews
Delta
8.0
Very good
7,969 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,969 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Harrisburg to Panama City round-trip?

    Cheapflights users have booked flights from Harrisburg to Panama City round-trip from $522. Other airlines that can offer you cheap pricing are American Airlines, from $564, and United Airlines, from $629. Delta is priced at 18% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Harrisburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama City.

  • Can I find deals for business class flights from Harrisburg to Panama City?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama City (average of $478). Flying from Harrisburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Harrisburg to Panama City

Discover the top 2 airlines that operate flights from Harrisburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$501Average$546FlexibilityNo cancel feeOn-time71%
DeltaCheapest$520Average$744FlexibilityNo cancel feeOn-timeN/A

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