Panama

$657+ Cheap flights from Harrisburg (MDT) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Jun 19 — Jun 261
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Harrisburg to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Harrisburg to Panama

Cheapest flights from Harrisburg to Panama
Explore the most affordable flight options available from Harrisburg to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.

This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:43 pm
MDT
-
PTY
2 stops19h 31m
American Airlines
Wed 7/151:14 pm
PTY
-
MDT
2 stops20h 57m
American Airlines
Deal found 5/19$657
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:59 pm
MDT
-
PTY
2 stops23h 38m
United Airlines
Mon 8/1010:55 pm
PTY
-
MDT
2 stops14h 09m
United Airlines
Deal found 5/17$667
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:55 pm
MDT
-
PTY
2 stops21h 19m
United Airlines
Fri 7/1010:55 pm
PTY
-
MDT
2 stops21h 34m
United Airlines
Deal found 5/19$700
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/195:52 pm
MDT
-
PTY
2 stops23h 20m
United Airlines
Fri 6/263:30 pm
PTY
-
MDT
2 stops21h 04m
United Airlines
Deal found 5/19$703
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:04 am
MDT
-
PTY
1 stop8h 05m
Delta
Fri 7/102:24 pm
PTY
-
MDT
1 stop8h 29m
Delta
Deal found 5/19$794
This Delta deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:04 am
MDT
-
PTY
1 stop8h 05m
Delta
Fri 6/262:24 pm
PTY
-
MDT
1 stop8h 31m
Delta
Deal found 5/19$936
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:10 pm
MDT
-
PTY
2 stops23h 18m
Multiple Airlines
Wed 7/1512:03 pm
PTY
-
MDT
1 stop28h 05m
Multiple Airlines
Deal found 5/19$1,006
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:40 pm
MDT
-
PTY
3 stops17h 33m
American Airlines
Fri 6/261:15 pm
PTY
-
MDT
2 stops10h 11m
American Airlines
Deal found 5/19$2,623
This KAYAK deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:30 am
MDT
-
PTY
2 stops10h 01m
Copa Airlines
Mon 8/109:13 am
PTY
-
MDT
1 stop8h 31m
Copa Airlines
Deal found 5/17$3,169

Find flight deals from Harrisburg to Panama

Keep the following information in mind while searching for Harrisburg to Panama flight deals. Data was last updated May 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$657
(American Airlines)
Provider with most accurate pricing for Harrisburg-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Harrisburg-Panama City Tocumen Intl flights.
From Harrisburg to Panama

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 8/6

7:59 pm-6:37 pm

2 stops23h 38m

Panama City Tocumen Intl

Mon 8/10

10:55 pm-2:04 pm

2 stops14h 09m

$667

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 7/3

5:55 pm-2:14 pm

2 stops21h 19m

Panama City Tocumen Intl

Fri 7/10

10:55 pm-9:29 pm

2 stops21h 34m

$700

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 6/19

5:52 pm-4:12 pm

2 stops23h 20m

Panama City Tocumen Intl

Fri 6/26

3:30 pm-1:34 pm

2 stops21h 04m

$703
Quickest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 7/3

6:04 am-1:09 pm

1 stop8h 05m

Panama City Tocumen Intl

Fri 7/10

2:24 pm-11:53 pm

1 stop8h 29m

$794

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 6/19

6:04 am-1:09 pm

1 stop8h 05m

Panama City Tocumen Intl

Fri 6/26

2:24 pm-11:55 pm

1 stop8h 31m

$936

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 7/8

5:34 pm-7:39 am

1 stop15h 05m

Panama City Tocumen Intl

Wed 7/15

12:03 pm-5:08 pm

1 stop28h 05m

$1,249

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 8/6

10:30 am-7:31 pm

2 stops10h 01m

Panama City Tocumen Intl

Mon 8/10

9:13 am-6:44 pm

1 stop8h 31m

$3,169

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/17

Sorted by cheapest first

Best time to book a flight from Harrisburg to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Harrisburg to Panama?

    Harrisburg (MDT), located 8.5 mi from the city center, is the airport you fly out of when you book flights from Harrisburg to Panama.

  • How long is the flight from Harrisburg to Panama?

    Departing from Harrisburg to Panama will take you 8h 05m. There are 2155 mi between Harrisburg and Panama. This flight may include one or multiple stops.

  • Can I find deals for flights from Harrisburg to Panama that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama.

  • Can I find deals for business class flights from Harrisburg to Panama?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.