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$249+ Cheap flights from Florence, SC (FLO) to the United States

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — LAX
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Find flight deals from Florence to USA

Cheapest flights from Florence to USA
Explore the most affordable flight options available from Florence to USA. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:16 amFLO - IAH
1 stop6h 42mAmerican Airlines
Tue 12/95:12 pmIAH - FLO
1 stop4h 41mAmerican Airlines
Deal found 11/2$249
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:29 amFLO - LGA
1 stop4h 31mAmerican Airlines
Tue 11/186:00 amLGA - FLO
1 stop4h 47mAmerican Airlines
Deal found 11/3$304
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:15 amFLO - LGA
1 stop6h 29mAmerican Airlines
Mon 11/105:32 pmLGA - FLO
1 stop5h 21mAmerican Airlines
Deal found 11/3$348
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:33 pmFLO - IAH
1 stop6h 45mAmerican Airlines
Mon 11/175:04 pmIAH - FLO
1 stop4h 49mAmerican Airlines
Deal found 11/2$349
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 pmFLO - BOS
1 stop4h 07mAmerican Airlines
Wed 12/311:35 pmBOS - FLO
1 stop6h 03mAmerican Airlines
Deal found 11/2$349
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 pmFLO - BOS
2 stops5h 29mAmerican Airlines
Tue 12/305:59 amBOS - FLO
2 stops6h 27mAmerican Airlines
Deal found 11/3$359
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 pmFLO - BOS
1 stop4h 07mAmerican Airlines
Mon 12/295:53 amBOS - FLO
1 stop6h 33mAmerican Airlines
Deal found 11/2$369
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:33 pmFLO - LGA
1 stop4h 55mAmerican Airlines
Tue 11/115:30 pmLGA - FLO
1 stop5h 23mAmerican Airlines
Deal found 11/3$378
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:15 amFLO - BOS
2 stops8h 04mAmerican Airlines
Sun 11/2310:18 amBOS - FLO
2 stops7h 49mAmerican Airlines
Deal found 11/3$379
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:31 pmFLO - JFK
1 stop3h 52mAmerican Airlines
Sun 12/76:30 amJFK - FLO
1 stop4h 21mAmerican Airlines
Deal found 11/2$380
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:31 pmFLO - LGA
1 stop4h 56mAmerican Airlines
Sun 12/76:00 amLGA - FLO
1 stop4h 51mAmerican Airlines
Deal found 11/2$380
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:29 amFLO - JFK
1 stop4h 28mAmerican Airlines
Wed 11/122:30 pmJFK - FLO
2 stops8h 23mAmerican Airlines
Deal found 11/3$383

Cheap flight deals from Florence to USA

Keep the following information in mind while searching for Florence to USA flight deals. Data was last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

Good round-trip deal

$474 or less

Good one-way deal

$366 or less
Provider with most accurate pricing for Florence-New York (NYC) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-New York (NYC) flights.
Search Deals
From Florence to USA
Search Deals
Price to beat on a round-trip flight from Florence to USA.
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Price to beat on a one-way flight from Florence to USA.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to USA that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Florence to the United States that are best for you.

Fly from

Florence

Fly to

USA

Route

Depart

Return

Price

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Thu 12/4

11:16 am-8:32 pm

2 stops10h 16m

Houston George Bush Intcntl

Tue 12/9

5:12 pm-10:53 pm

1 stop4h 41m

$254

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 11/19

10:29 am-2:57 pm

1 stop4h 28m

New York John F Kennedy Intl

Sun 11/23

6:30 am-10:45 am

1 stop4h 15m

$269

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 2/18

6:15 am-10:00 am

1 stop3h 45m

New York John F Kennedy Intl

Sat 2/21

11:00 am-5:49 pm

1 stop6h 49m

$299

FlorenceNew York

FLO - LGA

FLOLGA

Florence

Wed 2/18

6:15 am-11:59 am

1 stop5h 44m

New York LaGuardia

Sat 2/21

5:24 pm-11:59 pm

1 stop6h 35m

$299

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sat 2/28

5:15 am-11:25 am

1 stop7h 10m

Houston George Bush Intcntl

Wed 3/4

11:18 am-5:23 pm

1 stop5h 05m

$319

FlorenceHouston

FLO - IAH

FLOIAH

Florence

Sat 11/15

6:33 pm-12:18 am

1 stop6h 45m

Houston George Bush Intcntl

Mon 11/17

5:04 pm-10:53 pm

1 stop4h 49m

$349

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Sat 12/27

5:15 am-9:54 am

1 stop4h 39m

Boston Logan Intl

Wed 12/31

10:55 am-6:05 pm

1 stop7h 10m

$349

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Sat 12/27

5:15 am-9:54 am

1 stop4h 39m

Boston Logan Intl

Tue 12/30

7:57 am-12:26 pm

1 stop4h 29m

$349

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Fri 12/26

6:30 pm-10:37 pm

1 stop4h 07m

Boston Logan Intl

Tue 12/30

5:53 am-12:26 pm

1 stop6h 33m

$349

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Fri 12/26

6:30 pm-10:37 pm

1 stop4h 07m

Boston Logan Intl

Wed 12/31

9:00 am-6:05 pm

2 stops9h 05m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 44 results
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Best time to book a flight from Florence to USA

Have a flexible travel schedule? Discover the best time to fly to USA from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to the United States

What is the cheapest month to book a flight from Florence, South Carolina to USA?

Currently, April is the cheapest month in which you can book a flight from Florence, South Carolina to USA (average of $34). Flying from Florence, South Carolina to USA in August is currently the most expensive (average of $74). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing USA

Get insights into the airlines that provide service to USA. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to USA. Reviews last updated November 4, 2025.
Get a feel of what it's like to fly with American Airlines from Florence to the United States by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,040 reviews

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,040 reviews
American Airlines
7.2
Good
11,040 reviews

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Florence to USA. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to United States?

    For a flight from Florence to United States, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Florence, South Carolina to USA?

    A quick flight from Florence, South Carolina to USA can take about 10h 16m. American Airlines provides one of the quickest options available for as low as $254. There are 957 mi between Florence, South Carolina and USA.

  • What are the most popular routes from Florence, South Carolina to USA?

    The most popular flight routes from Florence, South Carolina to USA are Florence - Tampa, Florence - Las Vegas Harry Reid Intl and Florence - New York LaGuardia.

  • Can I find deals for flights from Florence to USA that include hotel bookings?

    Yes. In addition to deals on Florence to USA flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to USA?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to USA.

  • Can I find deals for business class flights from Florence to USA?

    Yes. Cheapflights offers flight deals from Florence to USA by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to USA?

    Currently, April is the cheapest month in which you can book a flight from Florence, South Carolina to USA (average of $34). Flying from Florence, South Carolina to USA in August is currently the most expensive (average of $74). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Florence to USA

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Florence to USA

Discover the top airline that operate flights from Florence to USA. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$209Average$492FlexibilityNo cancel feeOn-time71%

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