HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
USA

$107+ Cheap flights from Florence, SC (FLO) to the United States

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — LAX
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to USA with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florence to USA

Keep the following information in mind while searching for Florence to USA flight deals. Data was last updated September 11, 2025.

Round-trip from

$293
(American Airlines)

One-way from

$107
(American Airlines)

Good round-trip deal

$391 or less

Good one-way deal

$417 or less
From Florence to USA
Search Deals
One-way flight from Florence to USA
Search Deals
Price to beat on a round-trip flight from Florence to USA.
Search Deals
Price to beat on a one-way flight from Florence to USA.
Search Deals

Find flight deals from Florence to USA

Cheapest flights from Florence to USA
Explore the most affordable flight options available from Florence to USA. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:11 amFLO - ORD
1 stop5h 54mAmerican Airlines
Sat 10/187:10 amORD - FLO
1 stop5h 54mAmerican Airlines
Deal found 9/11$159
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Tue 9/302:33 pmHOU - FLO
2 stops7h 43mAmerican Airlines
Deal found 9/11$289
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:19 pmFLO - JFK
1 stop6h 40mAmerican Airlines
Sat 1/178:00 amJFK - FLO
1 stop6h 01mAmerican Airlines
Deal found 9/11$293
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:15 amFLO - JFK
2 stops7h 05mAmerican Airlines
Sat 1/172:59 pmJFK - FLO
2 stops8h 33mAmerican Airlines
Deal found 9/11$303
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:14 amFLO - ATL
2 stops14h 13mAmerican Airlines
Sat 11/18:48 amATL - FLO
2 stops10h 59mAmerican Airlines
Deal found 9/10$306
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:37 pmFLO - ORD
1 stop6h 35mAmerican Airlines
Tue 9/309:51 amORD - FLO
1 stop6h 21mAmerican Airlines
Deal found 9/11$320
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:14 amFLO - MCO
2 stops13h 30mAmerican Airlines
Wed 10/16:10 amMCO - FLO
2 stops11h 02mAmerican Airlines
Deal found 9/10$369
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:14 amFLO - SFO
1 stop8h 16mAmerican Airlines
Tue 9/3012:30 pmSFO - FLO
1 stop7h 46mAmerican Airlines
Deal found 9/11$375
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:11 amFLO - SFO
1 stop9h 43mAmerican Airlines
Tue 12/27:15 amSFO - FLO
1 stop6h 54mAmerican Airlines
Deal found 9/10$377
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:27 pmFLO - HOU
2 stops8h 44mAmerican Airlines
Sun 9/216:00 amHOU - FLO
2 stops9h 32mAmerican Airlines
Deal found 9/10$379
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:11 amFLO - SFO
2 stops12h 03mAmerican Airlines
Tue 12/27:15 amSFO - FLO
1 stop6h 54mAmerican Airlines
Deal found 9/10$382
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1711:11 amFLO - JAN
2 stops11h 50mAmerican Airlines
Tue 10/217:20 amJAN - FLO
2 stops14h 53mAmerican Airlines
Deal found 9/9$385

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to USA that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Florence to the United States that are best for you.

Fly from

Florence

Fly to

USA

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 10/11

11:11 am-4:05 pm

1 stop5h 54m

Chicago O'Hare Intl

Sat 10/18

7:10 am-2:04 pm

1 stop5h 54m

$159

FlorenceHouston

FLO - HOU

FLOHOU

Florence

Fri 9/26

12:27 pm-8:11 pm

2 stops8h 44m

Houston Hobby

Tue 9/30

2:33 pm-11:16 pm

2 stops7h 43m

$289

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 11/5

6:15 am-10:15 am

1 stop4h 00m

New York John F Kennedy Intl

Sat 1/17

7:30 pm-11:32 pm

1 stop4h 02m

$293

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 10/29

3:19 pm-9:59 pm

1 stop6h 40m

New York John F Kennedy Intl

Sat 1/17

8:00 am-2:01 pm

1 stop6h 01m

$293

FlorenceAtlanta

FLO - ATL

FLOATL

Florence

Sat 10/25

5:14 am-7:27 pm

2 stops14h 13m

Atlanta Hartsfield-Jackson

Sat 11/1

8:48 am-7:47 pm

2 stops10h 59m

$306

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 9/26

5:37 pm-11:12 pm

1 stop6h 35m

Chicago O'Hare Intl

Tue 9/30

9:51 am-5:12 pm

1 stop6h 21m

$320

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

2:33 pm-7:29 pm

1 stop5h 56m

Chicago O'Hare Intl

Sat 3/7

7:00 am-2:03 pm

1 stop6h 03m

$346

FlorenceNew York

FLO - JFK

FLOJFK

Florence

Wed 2/18

2:33 pm-8:00 pm

1 stop5h 27m

New York John F Kennedy Intl

Sat 2/21

2:59 pm-11:29 pm

2 stops8h 30m

$368

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Wed 9/24

6:14 am-7:44 pm

2 stops13h 30m

Orlando

Wed 10/1

6:10 am-5:12 pm

2 stops11h 02m

$369

FlorenceSan Francisco

FLO - SFO

FLOSFO

Florence

Fri 9/26

6:14 am-11:30 am

1 stop8h 16m

San Francisco

Tue 9/30

12:30 pm-11:16 pm

1 stop7h 46m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 36 results
1
2
3
4

Best time to book a flight from Florence to USA

Have a flexible travel schedule? Discover the best time to fly to USA from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to the United States

What is the cheapest month to book a flight from Florence, South Carolina to USA?

Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to USA (average of $246). Flying from Florence, South Carolina to USA in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing USA

Get insights into the airlines that provide service to USA. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to USA. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with American Airlines from Florence to the United States by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Florence to USA. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to United States?

    For a flight from Florence to United States, you will be flying from Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Florence, South Carolina to USA?

    A quick flight from Florence, South Carolina to USA can take about 5h 54m. American Airlines provides one of the quickest options available for as low as $159. There are 697 mi between Florence, South Carolina and USA.

  • What are the most popular routes from Florence, South Carolina to USA?

    The most popular flight routes from Florence, South Carolina to USA are Florence - Jackson-Evers Intl, Florence - Chicago O'Hare Intl and Florence - Tampa.

  • Can I find deals for flights from Florence to USA that include hotel bookings?

    Yes. In addition to deals on Florence to USA flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to USA?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to USA.

  • Can I find deals for business class flights from Florence to USA?

    Yes. Cheapflights offers flight deals from Florence to USA by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to USA?

    Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to USA (average of $246). Flying from Florence, South Carolina to USA in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to USA

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to Newark flights
Charlotte to LaGuardia flights
Charlotte to Las Vegas flights
Charlotte to Denver flights
Charlotte to O'Hare Intl flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Boston flights
Charlotte to Hobby flights
Charlotte to Fort Lauderdale flights
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to George Bush Intcntl flights
Charlotte to Cancún flights
Charlotte to Dulles Intl flights
Charlotte to Sky Harbor Intl flights
Charlotte to Baltimore flights
Charlotte to Los Angeles flights
Charlotte to Seattle flights
Charlotte to Love Field flights
Charlotte to Philadelphia flights
Charleston to Newark flights
Charleston to O'Hare Intl flights
Charlotte to Reagan-National flights
Charleston to John F Kennedy Intl flights
Charlotte to Minneapolis flights
Charleston to Denver flights
Savannah to John F Kennedy Intl flights
Greenville to Newark flights
Charlotte to Midway flights
Charleston to LaGuardia flights
Charlotte to Nashville flights
Charlotte to Salt Lake City flights
Charleston to Las Vegas flights
Greenville to John F Kennedy Intl flights
Charlotte to Atlanta flights
Greenville to LaGuardia flights
Charlotte to Austin flights
Savannah to Newark flights
Charlotte to New Orleans flights
Charlotte to Detroit flights
Charlotte to Cozumel flights
Charlotte to San Francisco flights
Charlotte to Honolulu flights
Charleston to Dallas/Fort Worth flights
Charlotte to Buffalo flights
Greenville to Dallas/Fort Worth flights
Greenville to Dulles Intl flights
Savannah to LaGuardia flights
Columbia to LaGuardia flights

Top airline flying from Florence to USA

Discover the top airline that operate flights from Florence to USA. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$213Average$486FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.