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$319+ Cheap flights from Florence, SC to Boston (FLO - BOS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — BOS
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Florence to Boston

Cheapest flights from Florence to Boston
Explore the most affordable flight options available from Florence to Boston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:05 am
FLO
-
BOS
1 stop4h 16m
American Airlines
Wed 7/17:00 am
BOS
-
FLO
1 stop7h 10m
American Airlines
Deal found 4/29$319
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:05 am
FLO
-
BOS
1 stop4h 16m
American Airlines
Wed 7/17:00 am
BOS
-
FLO
1 stop7h 10m
American Airlines
Deal found 4/29$399
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:05 am
FLO
-
BOS
1 stop4h 16m
American Airlines
Tue 6/308:14 am
BOS
-
FLO
2 stops5h 56m
American Airlines
Deal found 4/29$404
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:35 pm
FLO
-
BOS
2 stops6h 49m
American Airlines
Tue 6/305:31 am
BOS
-
FLO
2 stops8h 39m
American Airlines
Deal found 4/29$409
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:05 am
FLO
-
BOS
1 stop4h 17m
American Airlines
Mon 6/18:00 am
BOS
-
FLO
1 stop6h 10m
American Airlines
Deal found 4/26$419
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:05 am
FLO
-
BOS
1 stop4h 17m
American Airlines
Sun 5/316:00 am
BOS
-
FLO
2 stops8h 10m
American Airlines
Deal found 4/26$424
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:05 am
FLO
-
BOS
1 stop4h 17m
American Airlines
Mon 6/14:46 pm
BOS
-
FLO
1 stop5h 14m
American Airlines
Deal found 4/26$439
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:15 am
FLO
-
BOS
2 stops8h 04m
American Airlines
Tue 5/53:05 pm
BOS
-
FLO
2 stops7h 37m
American Airlines
Deal found 4/24$449

Find flight deals from Florence to Boston

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Boston (BOS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(American Airlines)
Provider with most accurate pricing for Florence-Boston Logan Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Boston Logan Intl flights.
Search Deals
From Florence to Boston Logan Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Boston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Florence to Boston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Wed 6/24

5:05 am-9:21 am

1 stop4h 16m

Boston Logan Intl

Wed 7/1

8:14 am-2:10 pm

2 stops5h 56m

$324

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Tue 6/23

5:05 am-9:21 am

1 stop4h 16m

Boston Logan Intl

Tue 6/30

8:14 am-2:10 pm

2 stops5h 56m

$404

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Wed 6/24

2:35 pm-9:24 pm

2 stops6h 49m

Boston Logan Intl

Tue 6/30

5:31 am-2:10 pm

2 stops8h 39m

$409

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Thu 5/28

5:05 am-11:11 am

1 stop6h 06m

Boston Logan Intl

Sat 5/30

8:00 am-2:10 pm

1 stop6h 10m

$419

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Tue 6/23

5:05 am-11:11 am

1 stop6h 06m

Boston Logan Intl

Thu 7/2

4:46 pm-11:33 pm

1 stop6h 47m

$419

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Sat 5/30

5:05 am-9:22 am

1 stop4h 17m

Boston Logan Intl

Sun 5/31

6:00 am-2:10 pm

2 stops8h 10m

$424

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Tue 5/12

6:15 am-10:52 am

1 stop4h 37m

Boston Logan Intl

Sat 5/16

2:12 pm-9:47 pm

1 stop7h 35m

$439

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Thu 5/28

5:05 am-11:46 am

2 stops6h 41m

Boston Logan Intl

Mon 6/1

4:46 pm-10:00 pm

1 stop5h 14m

$444

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Sat 5/16

5:20 am-11:12 am

1 stop5h 52m

Boston Logan Intl

Mon 5/18

9:30 am-3:50 pm

1 stop6h 20m

$469
Cheapest one-way
Quickest one-way

FlorenceBoston

FLO - BOS

FLOBOS

Florence

Tue 5/12

4:02 pm-8:36 pm

1 stop4h 34m

$413

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Florence to Boston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Boston in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Boston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Boston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Boston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Boston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Boston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Boston

Have a flexible travel schedule? Discover the best time to fly to Boston from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Florence to Boston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Boston?

    For as low as $324, American Airlines can have you in Boston from Florence, South Carolina in 4h 16m. Airlines will cover a distance of 735 mi.

  • Can I find deals for flights from Florence to Boston that include hotel bookings?

    Yes. In addition to deals on Florence to Boston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Boston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Boston.

  • Can I find deals for business class flights from Florence to Boston?

    Yes. Cheapflights offers flight deals from Florence to Boston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Boston?

Book flights to Boston if you plan to visit one of these locations
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Seabrook
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