$255+ Cheap flights from Florence, SC
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
Find flights from Florence within your budget
Fly to
Route
Depart
Return
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 3/13
5:09 am-9:00 am
1 stop4h 51m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
FlorenceNew York
FLO Florence - LGA New York LaGuardia
FLOLGA
Florence
Thu 12/24
2:35 pm-11:49 pm
2 stops9h 14m
New York LaGuardia
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
FlorenceNew York
FLO Florence - LGA New York LaGuardia
FLOLGA
Florence
Mon 12/21
2:35 pm-6:29 pm
1 stop3h 54m
New York LaGuardia
Tue 1/19
11:29 am-3:34 pm
1 stop4h 05m
FlorenceDallas
FLO Florence - DFW Dallas/Fort Worth
FLODFW
Florence
Wed 12/9
6:24 am-11:12 am
1 stop5h 48m
Dallas/Fort Worth
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
FlorenceNew York
FLO Florence - LGA New York LaGuardia
FLOLGA
Florence
Wed 12/23
2:35 pm-6:29 pm
1 stop3h 54m
New York LaGuardia
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Tue 12/29
5:09 am-11:00 am
1 stop6h 51m
Chicago O'Hare Intl
Thu 12/31
6:50 am-2:10 pm
1 stop6h 20m
FlorenceDallas
FLO Florence - DFW Dallas/Fort Worth
FLODFW
Florence
Mon 11/23
2:35 pm-7:15 pm
1 stop5h 40m
Dallas/Fort Worth
Wed 12/2
9:15 am-3:12 pm
1 stop4h 57m
FlorencePhoenix
FLO Florence - PHX Phoenix Sky Harbor Intl
FLOPHX
Florence
Wed 2/3
4:03 pm-8:55 pm
1 stop6h 52m
Phoenix Sky Harbor Intl
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
FlorenceFort Lauderdale
FLO Florence - FLL Fort Lauderdale
FLOFLL
Florence
Thu 11/26
8:00 am-3:06 pm
1 stop7h 06m
Fort Lauderdale
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
FlorenceNew York
FLO Florence - LGA New York LaGuardia
FLOLGA
Florence
Wed 11/4
6:24 am-11:23 am
1 stop4h 59m
New York LaGuardia
Sun 11/8
9:29 am-2:10 pm
1 stop4h 41m
Best time to book a flight from Florence
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Travel insights for flights from Florence
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What is the cheapest place to fly to from Florence, South Carolina?
The cheapest city to fly to from Florence, South Carolina is Charlotte Douglas, with prices starting at $273. Explore other affordable destinations below.
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Airports servicing Florence
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Fly from other United States cities
Consider departing from one of these cities also located in United States. Flight origins are based on user searches made on Cheapflights and were last updated on October 21, 2026.
Popular Round-Trip Flight Destinations
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Related info for your journey
Access useful and relevant information related to your journey from Florence. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated October 21, 2026.