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$372+ Cheap flights from Florence, SC to Denver (FLO - DEN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DEN
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Florence to Denver

Cheapest flights from Florence to Denver
Explore the most affordable flight options available from Florence to Denver. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:22 am
FLO
-
DEN
1 stop5h 49m
American Airlines
Sat 8/153:02 pm
DEN
-
FLO
1 stop5h 57m
American Airlines
Deal found 7/26$399
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:09 am
FLO
-
DEN
1 stop6h 08m
American Airlines
Mon 10/124:07 pm
DEN
-
FLO
1 stop5h 50m
American Airlines
Deal found 7/24$607
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 am
FLO
-
DEN
1 stop8h 08m
American Airlines
Tue 8/113:02 pm
DEN
-
FLO
1 stop5h 57m
American Airlines
Deal found 7/23$613

Find flight deals from Florence to Denver

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Denver (DEN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$399
(American Airlines)

One-way from

$372
(American Airlines)
Provider with most accurate pricing for Florence-Denver Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Denver Intl flights.
Search Deals
From Florence to Denver Intl
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One-way flight from Florence to Denver Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Denver that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Florence to Denver that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceDenver

FLO - DEN

FLODEN

Florence

Tue 8/11

6:22 am-10:11 am

1 stop5h 49m

Denver Intl

Sat 8/15

3:02 pm-10:59 pm

1 stop5h 57m

$399

FlorenceDenver

FLO - DEN

FLODEN

Florence

Fri 10/9

5:09 am-9:17 am

1 stop6h 08m

Denver Intl

Mon 10/12

4:07 pm-11:57 pm

1 stop5h 50m

$607

FlorenceDenver

FLO - DEN

FLODEN

Florence

Fri 8/7

6:22 am-12:30 pm

1 stop8h 08m

Denver Intl

Tue 8/11

3:02 pm-10:59 pm

1 stop5h 57m

$613
Cheapest one-way

FlorenceDenver

FLO - DEN

FLODEN

Florence

Mon 9/21

1:43 pm-12:17 am

2 stops12h 34m

$372
Quickest one-way

FlorenceDenver

FLO - DEN

FLODEN

Florence

Sat 8/1

2:35 pm-12:17 am

2 stops11h 42m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/23

Sorted by cheapest first

Compare providers for flights from Florence to Denver

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Denver in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Denver flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Denver flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Denver flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Denver flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Denver flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Denver

Have a flexible travel schedule? Discover the best time to fly to Denver from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Florence to Denver. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Denver?

    For as low as $399, American Airlines can have you in Denver from Florence, South Carolina in 5h 49m. Florence, South Carolina and Denver are separated by a distance of 1425 mi.

  • Can I find deals for flights from Florence to Denver that include hotel bookings?

    Yes. In addition to deals on Florence to Denver flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Denver?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Denver.

  • Can I find deals for business class flights from Florence to Denver?

    Yes. Cheapflights offers flight deals from Florence to Denver by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Denver?

Book flights to Denver if you plan to visit one of these locations
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