$559+ Cheap flights from Florence, SC to San Antonio (FLO - SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — SAT
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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Find cheap flights from Florence to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to San Antonio
Cheapest
Best
Last-minute
Cheapest flights from Florence to San AntonioExplore the most affordable flight options available from Florence to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from Florence to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:24 am -
1 stop5h 12m
Sat 10/37:10 am -
1 stop5h 08m
Deal found 9/14![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop4h 59m
Thu 10/17:10 am -
1 stop5h 08m
Deal found 9/12![American Airlines logo]()
$943
Best flights from Florence to San AntonioDiscover carefully curated flight deals from Florence to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from Florence to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:24 am -
1 stop5h 12m
Sat 10/37:10 am -
1 stop5h 08m
Deal found 9/14![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop4h 59m
Thu 10/112:41 pm -
2 stops9h 17m
Deal found 9/12![American Airlines logo]()
$984
Last-minute flights from Florence to San AntonioDiscover last-minute flight deals from Florence to San Antonio. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to San Antonio. Data last updated September 16, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:09 am -
1 stop4h 59m
Thu 10/17:10 am -
1 stop5h 08m
Deal found 9/12![American Airlines logo]()
$943
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:24 am -
1 stop5h 12m
Sat 10/37:10 am -
1 stop5h 08m
Deal found 9/14![American Airlines logo]()
$559
Find flight deals from Florence to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $559 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from Florence to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
FlorenceSan Antonio
FLO Florence - SAT San Antonio
FLOSAT
Florence
Tue 9/29
6:24 am-10:36 am
1 stop5h 12m
San Antonio
Sat 10/3
7:10 am-1:18 pm
1 stop5h 08m
$559
FlorenceSan Antonio
FLO Florence - SAT San Antonio
FLOSAT
Florence
Sun 9/27
5:09 am-9:08 am
1 stop4h 59m
San Antonio
Thu 10/1
12:41 pm-10:58 pm
2 stops9h 17m
$984
Sorted by cheapest first
Compare providers for flights from Florence to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to San Antonio in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Florence, South Carolina-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, South Carolina-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Florence with our price prediction graph.
FLO-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Florence to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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