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$125+ Cheap flights from the United States to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from USA to Panama

Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated July 31, 2025.

Round-trip from

$274
(Cheapflightsfares)

One-way from

$125
(FlightHub)

Popular in

December

Cheapest in

October

Average price

$608

Good round-trip deal

$285 or less

Good one-way deal

$148 or less
From USA to Panama
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One-way flight from USA to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from USA to Panama.
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Price to beat on a one-way flight from USA to Panama.
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Find flight deals from USA to Panama

Cheapest flights from USA to Panama
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/18:05 amMIA - PTY
1 stop13h 55mAvianca
Sat 11/89:55 pmPTY - MIA
1 stop13h 45mAvianca
Deal found 7/30$274
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/134:59 amMIA - PTY
Nonstop3h 07mCopa Airlines
Sat 11/228:01 amPTY - MIA
Nonstop3h 11mCopa Airlines
Deal found 7/31$349
This Cheapflightsfares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:55 pmMCO - PTY
1 stop10h 25mAvianca
Fri 11/73:19 amPTY - MCO
1 stop8h 56mAvianca
Deal found 7/29$377
This Copa Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/174:10 pmATL - PTY
Nonstop4h 23mCopa Airlines
Sun 8/319:25 amPTY - ATL
Nonstop4h 20mCopa Airlines
Deal found 7/31$391
This Avianca Connect deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1911:42 amATL - PTY
2 stops13h 28mMultiple Airlines
Mon 8/253:25 amPTY - ATL
2 stops15h 42mMultiple Airlines
Deal found 7/31$408
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/139:13 amMCO - PTY
1 stop28h 22mMultiple Airlines
Wed 8/201:30 pmPTY - MCO
1 stop26h 25mMultiple Airlines
Deal found 7/30$420
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:35 amDFW - PTY
2 stops18h 35mMultiple Airlines
Tue 9/2310:05 pmPTY - DFW
2 stops25h 49mMultiple Airlines
Deal found 7/28$445
This Avianca Connect deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2410:10 amEWR - PTY
2 stops12h 00mMultiple Airlines
Sun 9/283:20 amPTY - EWR
2 stops19h 09mMultiple Airlines
Deal found 7/30$448
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/203:20 pmIAD - PTY
1 stop9h 50mAvianca
Fri 9/2610:05 pmPTY - IAD
1 stop14h 55mAvianca
Deal found 7/29$453
This Avianca deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:35 amJFK - PTY
1 stop7h 50mAvianca
Mon 10/1311:00 amPTY - JFK
1 stop18h 00mAvianca
Deal found 7/29$454
This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/84:50 pmBOS - PTY
2 stops24h 40mAvianca
Mon 9/1511:00 amPTY - BOS
1 stop19h 15mAvianca
Deal found 7/30$456
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:00 amMCO - PTY
1 stop6h 55mDelta
Fri 10/32:10 pmPTY - MCO
1 stop9h 18mDelta
Deal found 7/31$457

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

USA

Fly to

Panama

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 9/18

11:15 am-9:10 pm

1 stop10h 55m

Panama City Tocumen Intl

Sun 9/21

10:05 pm-12:30 pm

1 stop13h 25m

$310

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 10/23

6:27 am-8:30 am

Nonstop3h 03m

Panama City Tocumen Intl

Tue 11/4

3:19 am-11:40 am

1 stop8h 21m

$372

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Sat 11/1

2:55 pm-12:20 am

1 stop10h 25m

Panama City Tocumen Intl

Fri 11/7

3:19 am-12:15 pm

1 stop8h 56m

$377

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Sun 8/17

4:10 pm-7:33 pm

Nonstop4h 23m

Panama City Tocumen Intl

Sun 8/31

9:25 am-2:45 pm

Nonstop4h 20m

$391

AtlantaPanama City

ATL - PTY

ATLPTY

Atlanta Hartsfield-Jackson

Tue 8/19

11:42 am-12:10 am

2 stops13h 28m

Panama City Tocumen Intl

Mon 8/25

3:25 am-8:07 pm

2 stops15h 42m

$408

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Wed 8/13

9:13 am-12:35 pm

1 stop28h 22m

Panama City Tocumen Intl

Wed 8/20

1:30 pm-4:55 pm

1 stop26h 25m

$420

DallasPanama City

DFW - PTY

DFWPTY

Dallas/Fort Worth

Sat 9/13

5:35 am-12:10 am

2 stops18h 35m

Panama City Tocumen Intl

Tue 9/23

10:05 pm-11:54 pm

2 stops25h 49m

$445

NewarkPanama City

EWR - PTY

EWRPTY

Newark

Wed 9/24

10:10 am-9:10 pm

2 stops12h 00m

Panama City Tocumen Intl

Sun 9/28

3:20 am-11:29 pm

2 stops19h 09m

$448

OrlandoPanama City

MCO - PTY

MCOPTY

Orlando

Thu 1/22

2:25 pm-5:53 pm

Nonstop3h 28m

Panama City Tocumen Intl

Mon 2/2

5:51 pm-9:22 pm

Nonstop3h 31m

$453

Washington, D.C.Panama City

IAD - PTY

IADPTY

Washington, D.C. Dulles Intl

Sat 9/20

3:20 pm-12:10 am

1 stop9h 50m

Panama City Tocumen Intl

Fri 9/26

10:05 pm-2:00 pm

1 stop14h 55m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 results
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Best time to book a flight from USA to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Panama

What is the cheapest month to book a flight from USA to Panama?

Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to PA?

Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to Panama as you normally would.

Weekly flight availability from USA to Panama

Explore weekly flight availability from USA to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 31, 2025.

The most flights from US0 to PA0 are scheduled on a Thursday (9 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from the United States to Panama, such as Delta, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,388 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this USA to Panama flight route?

    Within the past month, 161 users have taken a look at flights from United States to Panama.

  • What are the cheapest airlines to fly from USA to Panama one-way?

    One-way options have recently been found by users for as low as $125 on Avianca. Other airlines that offer cheap prices include Copa Airlines from $158 and American Airlines from $160 one-way.

  • Can I find deals for flights from USA to Panama that include hotel bookings?

    Yes. In addition to deals on USA to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Panama.

  • Can I find deals for business class flights from USA to Panama?

    Yes. Cheapflights offers flight deals from USA to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Panama?

    Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for USA to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to San Salvador flights
John F Kennedy Intl to San José flights
Newark to San José flights
Dulles Intl to San Salvador flights
John F Kennedy Intl to Panama City flights
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Dallas/Fort Worth to Panama City flights
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Dallas/Fort Worth to San Salvador flights
George Bush Intcntl to San Salvador flights
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LaGuardia to San José flights
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Miami to San José flights
Hobby to San José flights
Dulles Intl to San José flights
Los Angeles to Panama City flights
Newark to San Salvador flights
San Francisco to San José flights
O'Hare Intl to San José flights
Atlanta to San José flights
LaGuardia to Panama City flights
Orlando to Panama City flights
John F Kennedy Intl to Liberia flights
Baltimore to San Salvador flights
Newark to Liberia flights
George Bush Intcntl to San José flights
Denver to San José flights
Dulles Intl to Panama City flights
Boston to Panama City flights
Atlanta to Panama City flights
Dulles Intl to Guatemala City flights
Miami to San Salvador flights
O'Hare Intl to Liberia flights
Baltimore to San José flights
Fort Lauderdale to San José flights
O'Hare Intl to Panama City flights
Los Angeles to Liberia flights
Reagan-National to San Salvador flights
Dallas/Fort Worth to Guatemala City flights
LaGuardia to Guatemala City flights
Reagan-National to San José flights
Dallas/Fort Worth to San José flights
San Francisco to Guatemala City flights
Fort Lauderdale to Panama City flights

Top 5 airlines flying from USA to Panama

Discover the top 5 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$130Average$506FlexibilityNo cancel feeOn-time71%
DeltaCheapest$167Average$614FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$551FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$221Average$657FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$290Average$1,005FlexibilityNo cancel feeOn-time69%

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