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$104+ Cheap flights from the United States to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — PTY
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from USA to Panama

Keep the following information in mind while searching for USA to Panama flight deals. Data was last updated September 15, 2025.

Round-trip from

$272
(Cheapflightsfares)

One-way from

$104
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$494

Good round-trip deal

$279 or less

Good one-way deal

$134 or less
From USA to Panama
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One-way flight from USA to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from USA to Panama.
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Price to beat on a one-way flight from USA to Panama.
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Find flight deals from USA to Panama

Cheapest flights from USA to Panama
Explore the most affordable flight options available from USA to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2012:46 pmMIA - PTY
Nonstop3h 08mCopa Airlines
Tue 11/259:33 pmPTY - MIA
Nonstop3h 12mCopa Airlines
Deal found 9/15$276
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:55 amMIA - PTY
1 stop14h 15mAvianca
Mon 10/611:00 amPTY - MIA
1 stop16h 05mAvianca
Deal found 9/14$277
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:55 amMIA - PTY
1 stop14h 15mAvianca
Tue 10/2110:05 pmPTY - MIA
3 stops14h 50mAvianca
Deal found 9/13$278
This Gotogate deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:55 amMIA - PTY
1 stop9h 35mAvianca
Sun 10/51:30 pmPTY - MIA
2 stops9h 25mAvianca
Deal found 9/14$279
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/111:15 amMIA - PTY
1 stop10h 55mAvianca
Sun 10/51:30 pmPTY - MIA
2 stops9h 25mAvianca
Deal found 9/13$282
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:35 amMIA - PTY
2 stops8h 00mAvianca
Mon 10/2010:05 pmPTY - MIA
2 stops13h 10mAvianca
Deal found 9/14$283
This Trip.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:35 amMIA - PTY
2 stops8h 00mAvianca
Sat 10/255:25 pmPTY - MIA
1 stop9h 40mAvianca
Deal found 9/13$284
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:45 pmMIA - PTY
2 stops17h 40mAvianca
Tue 10/73:20 amPTY - MIA
1 stop13h 35mAvianca
Deal found 9/14$285
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:35 amMIA - PTY
2 stops8h 00mAvianca
Tue 10/219:55 amPTY - MIA
1 stop7h 00mAvianca
Deal found 9/13$286
This Viajes Éxito deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Éxito is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:35 amMIA - PTY
1 stop8h 00mAvianca
Thu 10/233:20 amPTY - MIA
1 stop13h 35mAvianca
Deal found 9/14$287
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/142:50 pmDFW - PTY
1 stop9h 20mAvianca
Sun 9/285:25 pmPTY - DFW
1 stop19h 55mAvianca
Deal found 9/14$371
This Avianca Connect deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/410:05 amEWR - PTY
2 stops12h 05mMultiple Airlines
Tue 10/73:20 amPTY - EWR
2 stops19h 09mMultiple Airlines
Deal found 9/13$376

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from the United States to Panama that are best for you.

Fly from

USA

Fly to

Panama

Route

Depart

Return

Price

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 11/20

12:46 pm-3:54 pm

Nonstop3h 08m

Panama City Tocumen Intl

Mon 11/24

10:38 am-1:49 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 10/1

6:27 am-8:30 am

Nonstop3h 03m

Panama City Tocumen Intl

Wed 10/8

3:44 pm-7:55 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Thu 11/13

4:59 am-8:06 am

Nonstop3h 07m

Panama City Tocumen Intl

Mon 11/17

6:11 pm-9:22 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 11/19

4:59 am-8:06 am

Nonstop3h 07m

Panama City Tocumen Intl

Tue 11/25

3:39 pm-6:51 pm

Nonstop3h 12m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Fri 10/17

6:27 am-8:30 am

Nonstop3h 03m

Panama City Tocumen Intl

Sun 10/19

3:44 pm-7:55 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Wed 10/29

5:12 pm-7:20 pm

Nonstop3h 08m

Panama City Tocumen Intl

Mon 11/3

6:34 pm-9:45 pm

Nonstop3h 11m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Tue 10/14

8:37 am-10:40 am

Nonstop3h 03m

Panama City Tocumen Intl

Fri 10/24

10:25 am-2:35 pm

Nonstop3h 10m

$276

MiamiPanama City

MIA - PTY

MIAPTY

Miami

Sun 11/16

5:24 am-8:30 am

Nonstop3h 06m

Panama City Tocumen Intl

Wed 11/19

10:38 am-1:49 pm

Nonstop3h 11m

$276

NewarkPanama City

EWR - PTY

EWRPTY

Newark

Fri 10/24

10:05 am-9:10 pm

2 stops12h 05m

Panama City Tocumen Intl

Sun 10/26

2:55 am-11:29 pm

2 stops19h 34m

$388

DallasPanama City

DFW - PTY

DFWPTY

Dallas/Fort Worth

Mon 11/3

2:00 pm-8:50 am

1 stop17h 50m

Panama City Tocumen Intl

Sat 11/8

5:55 pm-12:35 pm

1 stop19h 40m

$403

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
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Best time to book a flight from USA to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to Panama

What is the cheapest month to book a flight from USA to Panama?

Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to PA?

Find hourly flight availability from USA to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to Panama as you normally would.

Weekly flight availability from USA to Panama

Explore weekly flight availability from USA to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from US0 to PA0 are scheduled on a Monday (9 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from the United States to Panama, such as Delta, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,435 reviews
Delta
8.0
Very good
7,954 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from USA to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this USA to Panama flight route?

    Within the past month, 160 users have taken a look at flights from United States to Panama.

  • How long is the flight from USA to Panama?

    Airlines like Copa Airlines and Avianca fly from USA to Panama in about 3h 08m. The time it takes to get you to your destination can typically vary by up to 14h 42m. There are 1156 mi between USA and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from USA to Panama that include hotel bookings?

    Yes. In addition to deals on USA to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to Panama.

  • Can I find deals for business class flights from USA to Panama?

    Yes. Cheapflights offers flight deals from USA to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to Panama?

    Currently, October is the cheapest month in which you can book a flight from USA to Panama (average of $478). Flying from USA to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for USA to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San José flights
Los Angeles to Guatemala City flights
Los Angeles to San Salvador flights
Newark to San José flights
Dulles Intl to San Salvador flights
John F Kennedy Intl to Panama City flights
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John F Kennedy Intl to Guatemala City flights
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George Bush Intcntl to San Salvador flights
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LaGuardia to San José flights
Hobby to San José flights
Dulles Intl to Panama City flights
Los Angeles to Panama City flights
Dulles Intl to San José flights
Dallas/Fort Worth to San José flights
Miami to Panama City flights
Atlanta to San José flights
George Bush Intcntl to San José flights
LaGuardia to Panama City flights
John F Kennedy Intl to Liberia flights
O'Hare Intl to Panama City flights
Boston to San José flights
Dulles Intl to Guatemala City flights
Miami to Managua flights
O'Hare Intl to Guatemala City flights
Denver to San José flights
Dallas/Fort Worth to Panama City flights
Baltimore to San Salvador flights
Hobby to Panama City flights
San Francisco to San José flights
Baltimore to San José flights
Reagan-National to San José flights
LaGuardia to Guatemala City flights
Reagan-National to San Salvador flights
Atlanta to San Salvador flights
Orlando to Panama City flights
Miami to San Salvador flights
O'Hare Intl to Liberia flights
Miami to San José flights
LaGuardia to San Salvador flights
Ontario to San Salvador flights
Los Angeles to Liberia flights
LaGuardia to Liberia flights

Top 5 airlines flying from USA to Panama

Discover the top 5 airlines that operate flights from USA to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$132Average$503FlexibilityNo cancel feeOn-time71%
DeltaCheapest$167Average$616FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$203Average$554FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$222Average$644FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$290Average$1,005FlexibilityNo cancel feeOn-time69%

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