Ohio

$49+ Cheap flights from South Carolina to Ohio

CHS — CLE
Dec 9 — Dec 161
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Cheap flight deals from South Carolina to Ohio

Cheapest flights from South Carolina to Ohio

Thu 12/177:46 pm -
Nonstop1h 44m
Sun 12/205:17 pm -
Nonstop1h 39m
Deal found 11/7$66
Thu 12/33:00 pm -
Nonstop1h 47m
Sun 12/612:27 pm -
Nonstop1h 43m
Deal found 11/6$69
Thu 12/33:00 pm -
Nonstop1h 47m
Sun 12/1312:27 pm -
Nonstop1h 43m
Deal found 11/6$71
Tue 12/87:00 am -
Nonstop1h 51m
Thu 12/1012:27 pm -
Nonstop1h 43m
Deal found 11/4$97
Fri 12/44:27 pm -
Nonstop1h 25m
Fri 12/116:32 pm -
Nonstop1h 20m
Deal found 11/5$97
Thu 11/193:04 pm -
Nonstop1h 45m
Sun 11/2212:38 pm -
Nonstop1h 36m
Deal found 11/5$98
Fri 12/44:27 pm -
Nonstop1h 25m
Mon 12/76:32 pm -
Nonstop1h 20m
Deal found 11/8$98
Sun 12/137:00 am -
Nonstop1h 51m
Sun 12/1312:27 pm -
Nonstop1h 43m
Deal found 11/7$100
Thu 12/106:45 am -
Nonstop1h 44m
Sun 12/131:22 pm -
Nonstop1h 43m
Deal found 11/8$103
Sun 12/66:45 am -
Nonstop1h 44m
Sun 12/131:22 pm -
Nonstop1h 43m
Deal found 11/8$108
Thu 11/122:57 pm -
Nonstop1h 42m
Sun 11/1511:58 am -
Nonstop1h 39m
Deal found 11/4$108
Fri 12/184:27 pm -
Nonstop1h 25m
Fri 1/16:32 pm -
Nonstop1h 20m
Deal found 11/5$128

Find flight deals from South Carolina to Ohio

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$66
(CheapOair)

One-way from

$48
(Kiwi.com)

Popular in

November

Cheapest in

April

Average price

$516

Good round-trip deal

$114 or less

Good one-way deal

$52 or less
Provider with most accurate pricing for Myrtle Beach Intl-Cleveland Hopkins Intl flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Cleveland Hopkins Intl flights.
From South Carolina to Ohio
One-way flight from South Carolina to Ohio
Highest demand for flights based on searches. 18% potential increase in price ($72 potential increase over avg. RT price).
Cheapest flight prices on average. 6% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in November 2026
Price to beat on a round-trip flight from South Carolina to Ohio.
Price to beat on a one-way flight from South Carolina to Ohio.

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from South Carolina to Ohio that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonCincinnati

CHS Charleston - CVG Cincinnati Cinci./N. Kentucky

CHSCVG

Charleston

Thu 11/19

3:04 pm-4:49 pm

Nonstop1h 45m

Cincinnati Cinci./N. Kentucky

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$58

Myrtle BeachAkron

MYR Myrtle Beach Intl - CAK Akron/Canton

MYRCAK

Myrtle Beach Intl

Wed 12/16

10:08 am-12:00 pm

Nonstop1h 52m

Akron/Canton

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$58
Quickest round-trip

GreenvilleColumbus

GSP Greenville - CMH Columbus

GSPCMH

Greenville

Mon 11/23

4:27 pm-5:52 pm

Nonstop1h 25m

Columbus

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$72

CharlestonCincinnati

CHS Charleston - CVG Cincinnati Cinci./N. Kentucky

CHSCVG

Charleston

Tue 12/1

2:04 pm-5:40 pm

1 stop3h 36m

Cincinnati Cinci./N. Kentucky

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$89

CharlestonCincinnati

CHS Charleston - CVG Cincinnati Cinci./N. Kentucky

CHSCVG

Charleston

Tue 12/1

1:21 pm-3:59 pm

2 stops26h 38m

Cincinnati Cinci./N. Kentucky

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$103

GreenvilleColumbus

GSP Greenville - CMH Columbus

GSPCMH

Greenville

Fri 12/4

4:27 pm-5:52 pm

Nonstop1h 25m

Columbus

Fri 12/11

6:32 pm-7:52 pm

Nonstop1h 20m

$103

CharlestonColumbus

CHS Charleston - CMH Columbus

CHSCMH

Charleston

Sun 11/15

6:45 am-8:29 am

Nonstop1h 44m

Columbus

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$108

CharlestonColumbus

CHS Charleston - CMH Columbus

CHSCMH

Charleston

Sun 12/6

6:45 am-8:29 am

Nonstop1h 44m

Columbus

Sun 12/13

1:22 pm-3:05 pm

Nonstop1h 43m

$108

CharlestonCincinnati

CHS Charleston - CVG Cincinnati Cinci./N. Kentucky

CHSCVG

Charleston

Sun 11/22

7:00 am-8:51 am

Nonstop1h 51m

Cincinnati Cinci./N. Kentucky

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$113

CharlestonCincinnati

CHS Charleston - CVG Cincinnati Cinci./N. Kentucky

CHSCVG

Charleston

Thu 12/10

7:00 am-8:51 am

Nonstop1h 51m

Cincinnati Cinci./N. Kentucky

Thu 1/7

7:13 pm-8:59 pm

Nonstop1h 46m

$113

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from South Carolina with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Ohio

What is the cheapest month to book a flight from South Carolina to Ohio?

Currently, July is the cheapest month in which you can book a flight from South Carolina to Ohio (average of $241). Flying from South Carolina to Ohio in October is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to OH?

When flying from South Carolina to Ohio, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 20% versus a flight in the morning.

How much does it cost to fly round-trip from South Carolina to Ohio?

Airfare is below average for this route at the moment.
South Carolina to Ohio flights typically cost between $359 and $536 in February.
The cheapest round-trip price found within the last 5 days was $193 on Multiple Airlines (Feb 17-Feb 23).

What is the cheapest day to fly from South Carolina to Ohio?

Travelers seeking maximum savings on their South Carolina to Ohio flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Ohio

Read through reviews of airlines operating flights from South Carolina to Ohio, such as Breeze Airways,Southwest, andDelta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Comfort

8.2

Overall

8.2

Boarding

8.4

Crew

8.8

Food

6.7

Entertainment

6.8

Reviews

1 / 17
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Related info for your journey

  • How long is the flight from South Carolina to Ohio?

    Breeze Airways and Delta can get you from South Carolina to Ohio in just under 1h 25m. Your travel time can differ by up to 3h 40m. The distance from South Carolina to Ohio is about 354 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Ohio one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $124. However, be on the lookout for offers from Aeromexico and American Airlines, as they are both options that can get you from South Carolina to Ohio for a low price.

  • Can I find deals for flights from South Carolina to Ohio that include hotel bookings?

    Yes. In addition to deals on South Carolina to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Ohio.

  • Can I find deals for business class flights from South Carolina to Ohio?

    Yes. Cheapflights offers flight deals from South Carolina to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Ohio?

    Currently, July is the cheapest month in which you can book a flight from South Carolina to Ohio (average of $241). Flying from South Carolina to Ohio in October is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Carolina to Ohio

Top 7 airlines flying from South Carolina to Ohio

AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$40Average$141FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$69Average$176FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$74Average$90FlexibilityNo cancel feeOn-time62%
DeltaCheapest$88Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$158Average$407FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$394FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$246Average$395FlexibilityNo cancel feeOn-time69%

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