$46+ Cheap flights from South Carolina to Ohio
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CLE
Aug 12 — Aug 191
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Ohio with Cheapflights
1. Tell us where you want to go
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Cheapest flights from South Carolina to OhioExplore the most affordable flight options available from South Carolina to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from South Carolina to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:32 pm
MYR
- CAK
Nonstop1h 36m
Allegiant Air
Sun 11/112:20 pm
CAK
- MYR
Nonstop1h 37m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm
MYR
- CAK
Nonstop1h 40m
Allegiant Air
Sun 8/302:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$81
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Sun 8/1610:39 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$89
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Sun 8/232:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$99
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:15 pm
MYR
- CAK
Nonstop1h 37m
Multiple Airlines
Mon 9/148:00 am
CAK
- MYR
Nonstop1h 37m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$102
This Trip.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:15 pm
MYR
- CAK
Nonstop1h 40m
Allegiant Air
Sun 8/232:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$112
This Mytrip deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:17 am
MYR
- CAK
Nonstop1h 52m
Multiple Airlines
Sun 9/202:47 pm
CAK
- MYR
Nonstop1h 38m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:48 am
MYR
- CAK
Nonstop1h 52m
Breeze Airways
Fri 10/28:00 am
CAK
- MYR
Nonstop1h 37m
Breeze Airways
Deal found 7/11![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:21 pm
MYR
- CAK
Nonstop1h 39m
Multiple Airlines
Tue 8/44:45 pm
CAK
- MYR
Nonstop1h 40m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$142
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:21 pm
MYR
- CAK
Nonstop1h 39m
Allegiant Air
Sun 8/210:53 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Mon 8/310:53 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:13 pm
GSP
- DTW
1 stop16h 31m
Multiple Airlines
Sat 8/2910:18 am
DTW
- GSP
1 stop21h 39m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$195
Best flights from South Carolina to OhioDiscover carefully curated flight deals from South Carolina to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from South Carolina to Ohio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Multiple Airlines
Sun 8/236:00 am
CAK
- MYR
1 stop9h 14m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:30 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Mon 8/310:53 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$228
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:35 am
CLT
- CLE
1 stop6h 00m
Southwest
Sat 8/155:40 am
CLE
- CLT
1 stop4h 15m
Southwest
Deal found 7/8![Southwest logo]()
$240
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:33 am
MYR
- DTW
Nonstop1h 57m
Delta
Sun 8/168:41 am
DTW
- MYR
Nonstop1h 57m
Delta
Deal found 7/12![Delta logo]()
$299
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:50 pm
SAV
- DTW
1 stop7h 00m
JetBlue
Thu 10/226:00 am
DTW
- SAV
1 stop7h 18m
JetBlue
Deal found 7/12![JetBlue logo]()
$302
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:10 am
CHS
- DTW
2 stops6h 50m
Southwest
Mon 9/145:30 am
DTW
- CHS
1 stop5h 20m
Southwest
Deal found 7/10![Southwest logo]()
$241
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:25 am
CLT
- CVG
2 stops13h 30m
United Airlines
Wed 8/1211:17 am
CVG
- CLT
1 stop10h 24m
United Airlines
Deal found 7/9![United Airlines logo]()
$498
This Breeze Airways deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:30 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Sun 8/26:00 am
CAK
- MYR
1 stop9h 14m
Breeze Airways
Deal found 7/11![Breeze Airways logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:53 pm
MYR
- DTW
1 stop25h 29m
Multiple Airlines
Sat 8/295:21 pm
DTW
- MYR
1 stop15h 34m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 pm
CLT
- PIT
1 stop3h 30m
Southwest
Sat 9/51:55 pm
PIT
- CLT
1 stop4h 25m
Southwest
Deal found 7/8![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:30 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Mon 8/1710:53 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 7/12![Breeze Airways logo]()
$267
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:33 am
MYR
- DTW
Nonstop1h 57m
Delta
Sun 8/308:41 am
DTW
- MYR
Nonstop1h 57m
Delta
Deal found 7/10![Delta logo]()
$299
This JetBlue deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:50 am
CHS
- DTW
1 stop5h 00m
JetBlue
Sun 11/18:10 am
DTW
- CHS
1 stop6h 56m
JetBlue
Deal found 7/11![JetBlue logo]()
$302
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:50 am
CLT
- PIT
1 stop5h 55m
Southwest
Wed 9/232:00 pm
PIT
- CLT
1 stop7h 10m
Southwest
Deal found 7/9![Southwest logo]()
$257
This Breeze Airways deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:25 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Sun 8/29:41 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 7/9![Breeze Airways logo]()
$268
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:10 am
CHS
- DTW
Nonstop2h 07m
Delta
Sat 9/197:59 pm
DTW
- CHS
Nonstop2h 14m
Delta
Deal found 7/13![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:20 pm
CLT
- CMH
1 stop3h 30m
Southwest
Thu 10/15:50 am
CMH
- CLT
1 stop4h 10m
Southwest
Deal found 7/8![Southwest logo]()
$257
This Breeze Airways deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:48 am
MYR
- CAK
Nonstop1h 52m
Breeze Airways
Thu 10/86:55 am
CAK
- MYR
1 stop5h 19m
Breeze Airways
Deal found 7/8![Breeze Airways logo]()
$275
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:02 pm
MYR
- DTW
1 stop5h 57m
Delta
Wed 8/128:41 am
DTW
- MYR
Nonstop1h 57m
Delta
Deal found 7/8![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:25 am
CLT
- CVG
1 stop4h 15m
Southwest
Tue 9/85:40 am
CVG
- CLT
1 stop4h 35m
Southwest
Deal found 7/8![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:30 am
CLT
- PIT
2 stops9h 20m
Southwest
Sat 10/36:20 am
PIT
- CLT
1 stop6h 45m
Southwest
Deal found 7/9![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:02 pm
MYR
- DTW
1 stop5h 57m
Delta
Mon 8/175:20 am
DTW
- MYR
1 stop5h 27m
Delta
Deal found 7/9![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:35 am
CLT
- PIT
2 stops7h 05m
Southwest
Mon 8/314:10 pm
PIT
- CLT
1 stop4h 30m
Southwest
Deal found 7/10![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:02 pm
MYR
- DTW
1 stop5h 57m
Delta
Sat 8/85:20 am
DTW
- MYR
1 stop5h 27m
Delta
Deal found 7/8![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:50 am
SAV
- DTW
1 stop6h 25m
Southwest
Tue 10/136:10 am
DTW
- SAV
1 stop6h 35m
Southwest
Deal found 7/8![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:17 pm
CLT
- DTW
Nonstop1h 43m
Delta
Sat 8/2910:30 am
DTW
- CLT
Nonstop1h 47m
Delta
Deal found 7/12![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:25 am
CLT
- CVG
2 stops10h 18m
United Airlines
Tue 8/1811:17 am
CVG
- CLT
1 stop10h 24m
United Airlines
Deal found 7/10![United Airlines logo]()
$535
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:30 pm
CLT
- PIT
2 stops8h 00m
Southwest
Sat 8/296:10 am
PIT
- CLT
2 stops8h 15m
Southwest
Deal found 7/8![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:59 pm
CHS
- DTW
Nonstop2h 09m
Delta
Mon 9/148:55 am
DTW
- CHS
1 stop5h 03m
Delta
Deal found 7/10![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
CLT
- CVG
2 stops9h 33m
United Airlines
Tue 8/411:17 am
CVG
- CLT
1 stop10h 12m
United Airlines
Deal found 7/8![United Airlines logo]()
$535
Last-minute flights from South Carolina to OhioDiscover last-minute flight deals from South Carolina to Ohio. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Ohio. Data last updated July 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Mon 8/310:53 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:21 pm
MYR
- CAK
Nonstop1h 39m
Multiple Airlines
Tue 8/44:45 pm
CAK
- MYR
Nonstop1h 40m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$142
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:21 pm
MYR
- CAK
Nonstop1h 39m
Allegiant Air
Sun 8/210:53 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:21 pm
MYR
- CAK
Nonstop1h 39m
Multiple Airlines
Mon 8/310:53 am
CAK
- MYR
Nonstop1h 40m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$164
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Sun 8/1610:39 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$89
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Sun 8/232:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$99
This Booking.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:07 pm
MYR
- CAK
Nonstop1h 42m
Multiple Airlines
Sun 8/236:00 am
CAK
- MYR
1 stop9h 14m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Wed 8/2610:18 am
DTW
- SAV
1 stop7h 37m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$196
This Trip.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:15 pm
MYR
- CAK
Nonstop1h 40m
Allegiant Air
Sun 8/232:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/10![Allegiant Air logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:13 pm
GSP
- DTW
1 stop16h 31m
Multiple Airlines
Sat 8/2910:18 am
DTW
- GSP
1 stop21h 39m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm
MYR
- CAK
Nonstop1h 40m
Allegiant Air
Sun 8/302:46 pm
CAK
- MYR
Nonstop1h 39m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:15 pm
MYR
- CAK
Nonstop1h 40m
Multiple Airlines
Sun 8/307:25 am
CAK
- MYR
2 stops26h 25m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$170
One-way flights from South Carolina to OhioSearch for one-way flight options from South Carolina to Ohio. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from South Carolina to Ohio. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:05 pm
MYR
- CAK
Nonstop1h 36m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$46
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:44 pm
MYR
- CAK
Nonstop1h 52m
Breeze Airways
Deal found 7/11![Breeze Airways logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 7/11![Breeze Airways logo]()
$68
This Super.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:38 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 7/10![Breeze Airways logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 7/12![Breeze Airways logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:04 pm
CHS
- DTW
1 stop18h 58m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:17 am
MYR
- CAK
Nonstop1h 52m
Breeze Airways
Deal found 7/11![Breeze Airways logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:38 pm
CLT
- DTW
1 stop21h 54m
Frontier
Deal found 7/12![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:38 pm
CLT
- DTW
1 stop21h 54m
Frontier
Deal found 7/13![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:52 pm
CLT
- CLE
1 stop10h 04m
Frontier
Deal found 7/11![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:29 pm
GSP
- DTW
1 stop24h 38m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:38 pm
CLT
- PIT
2 stops27h 29m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$98
Find flight deals from South Carolina to Ohio
Keep the following information in mind while searching for South Carolina to Ohio flight deals. Data was last updated July 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $75 (Kiwi.com) |
One-way from | $46 (Kiwi.com) |
Popular in | March |
Cheapest in | April |
Average price | $151 |
Good round-trip deal | $86 or less |
Good one-way deal | $58 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from South Carolina to Ohio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachAkron
MYR - CAK
MYRCAK
Myrtle Beach Intl
Thu 8/13
1:07 pm-2:49 pm
Nonstop1h 42m
Akron/Canton
Sun 8/23
6:00 am-3:14 pm
1 stop9h 14m
$177
Quickest round-trip
Myrtle BeachAkron
MYR - CAK
MYRCAK
Myrtle Beach Intl
Fri 7/31
8:30 am-10:13 am
Nonstop1h 43m
Akron/Canton
Mon 8/3
10:53 am-12:33 pm
Nonstop1h 40m
$228
CharlotteCleveland
CLT - CLE
CLTCLE
Charlotte Douglas
Thu 8/13
6:35 am-12:35 pm
1 stop6h 00m
Cleveland Hopkins Intl
Sat 8/15
5:40 am-9:55 am
1 stop4h 15m
$240
CharlestonDetroit
CHS - DTW
CHSDTW
Charleston
Wed 9/2
8:10 am-3:00 pm
2 stops6h 50m
Detroit Metropolitan Wayne County
Mon 9/14
5:30 am-10:50 am
1 stop5h 20m
$241
Myrtle BeachAkron
MYR - CAK
MYRCAK
Myrtle Beach Intl
Fri 7/31
8:30 am-10:13 am
Nonstop1h 43m
Akron/Canton
Sun 8/2
6:00 am-3:14 pm
1 stop9h 14m
$252
CharlottePittsburgh
CLT - PIT
CLTPIT
Charlotte Douglas
Sat 8/29
5:15 pm-8:45 pm
1 stop3h 30m
Pittsburgh
Sat 9/5
1:55 pm-6:20 pm
1 stop4h 25m
$257
CharlottePittsburgh
CLT - PIT
CLTPIT
Charlotte Douglas
Tue 9/8
6:50 am-12:45 pm
1 stop5h 55m
Pittsburgh
Wed 9/23
2:00 pm-9:10 pm
1 stop7h 10m
$257
CharlotteColumbus
CLT - CMH
CLTCMH
Charlotte Douglas
Mon 9/28
7:20 pm-10:50 pm
1 stop3h 30m
Columbus
Thu 10/1
5:50 am-10:00 am
1 stop4h 10m
$257
CharlotteCincinnati
CLT - CVG
CLTCVG
Charlotte Douglas
Sat 9/5
8:25 am-12:40 pm
1 stop4h 15m
Cincinnati Cinci./N. Kentucky
Tue 9/8
5:40 am-10:15 am
1 stop4h 35m
$257
Myrtle BeachDetroit
MYR - DTW
MYRDTW
Myrtle Beach Intl
Tue 8/25
3:53 pm-5:22 pm
1 stop25h 29m
Detroit Metropolitan Wayne County
Sat 8/29
5:21 pm-8:55 am
1 stop15h 34m
$262
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Ohio
Have a flexible travel schedule? Discover the best time to fly to Ohio from South Carolina with our price prediction graph.
MYR-CAK
GSP-DTW
CHS-DTW
CLT-DTW
CLT-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Ohio
USSC-USOH
MYR-CAK
GSP-DTW
CHS-DTW
CLT-DTW
What is the cheapest month to book a flight from South Carolina to Ohio?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Ohio (average of $40). Flying from South Carolina to Ohio in February is currently the most expensive (average of $98). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to OH?
Find hourly flight availability from South Carolina to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 13, 2026.
When flying from South Carolina to Ohio, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 49% versus a flight in the morning.
How much does it cost to fly round-trip from South Carolina to Ohio?
What is the cheapest day to fly from South Carolina to Ohio?
Use this chart to determine the cheapest time to fly round-trip from South Carolina to Ohio. Price data was last updated on July 11, 2026.
Travelers seeking maximum savings on their South Carolina to Ohio flight should consider departing on Monday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Ohio
Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated July 13, 2026.
Read through reviews of airlines operating flights from South Carolina to Ohio, such as Breeze Airways,Southwest, andDelta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.7
Overall
8.2
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Top destinations
Alternative routes for South Carolina to Ohio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Ohio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Ohio by cabin class
Find flights from South Carolina to Ohio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Ohio flights
Browse other South Carolina and Ohio flight options. Last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Ohio
Find the right flight back to South Carolina after your stay in Ohio
South Carolina to Ohio flights
Consider these flights traveling from South Carolina to Ohio.
Top 7 airlines flying from South Carolina to Ohio
Discover the top 7 airlines that operate flights from South Carolina to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$40 | Average$127 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$53 | Average$173 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$74 | Average$90 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$88 | Average$353 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$194 | Average$367 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$355 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$246 | Average$376 | FlexibilityNo cancel fee | On-time69% |