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$49+ Cheap flights from South Carolina to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CVG
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from South Carolina to Ohio

Keep the following information in mind while searching for South Carolina to Ohio flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$101
(Priceline)

One-way from

$49
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$399

Good round-trip deal

$85 or less

Good one-way deal

$69 or less
Provider with most accurate pricing for Myrtle Beach Intl-Cleveland Hopkins Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Cleveland Hopkins Intl flights.
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From South Carolina to Ohio
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One-way flight from South Carolina to Ohio
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Highest demand for flights based on searches. 23% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Price to beat on a round-trip flight from South Carolina to Ohio.
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Price to beat on a one-way flight from South Carolina to Ohio.
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Find flight deals from South Carolina to Ohio

Cheapest flights from South Carolina to Ohio
Explore the most affordable flight options available from South Carolina to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Priceline deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/225:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Mon 1/268:00 amDTW - CHS
1 stop9h 36mSpirit Airlines
Deal found 1/7$101
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/225:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Sun 1/2510:08 pmDTW - CHS
1 stop18h 02mSpirit Airlines
Deal found 1/6$114
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/225:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Sun 2/15:00 amDTW - CHS
1 stop11h 10mSpirit Airlines
Deal found 1/5$118
This Mytrip deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Sun 2/85:00 amDTW - CHS
1 stop11h 10mSpirit Airlines
Deal found 1/7$122
This Cheapflightsfares deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:35 pmCHS - PIT
1 stop5h 09mSpirit Airlines
Mon 2/26:00 amPIT - CHS
1 stop11h 39mSpirit Airlines
Deal found 1/7$122
This Mytrip deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:00 pmCHS - DTW
1 stop7h 09mSpirit Airlines
Sat 2/285:09 amDTW - CHS
1 stop10h 56mSpirit Airlines
Deal found 1/7$127
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Mon 2/25:00 amDTW - CHS
1 stop11h 10mSpirit Airlines
Deal found 1/6$129
This Expedia deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:00 amCLT - CLE
1 stop12h 06mSpirit Airlines
Mon 1/267:01 pmCLE - CLT
1 stop5h 39mSpirit Airlines
Deal found 1/7$130
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/95:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Wed 2/185:09 amDTW - CHS
1 stop10h 46mSpirit Airlines
Deal found 1/7$130
This Cheapflightsfares deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:35 pmCHS - PIT
1 stop5h 09mSpirit Airlines
Sun 2/86:00 amPIT - CHS
1 stop11h 39mSpirit Airlines
Deal found 1/7$133
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:05 pmCHS - DTW
1 stop7h 14mSpirit Airlines
Sun 2/2210:59 pmDTW - CHS
1 stop17h 06mSpirit Airlines
Deal found 1/7$135
This Cheapflightsfares deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:00 amCLT - CLE
1 stop12h 06mSpirit Airlines
Sun 1/257:01 pmCLE - CLT
1 stop5h 39mSpirit Airlines
Deal found 1/6$136

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from South Carolina to Ohio that are best for you.

Fly from

South Carolina

Fly to

Ohio

Route

Depart

Return

Price

CharlestonPittsburgh

CHS - PIT

CHSPIT

Charleston

Fri 2/6

6:35 pm-11:44 pm

1 stop5h 09m

Pittsburgh

Sun 2/8

6:00 am-5:39 pm

1 stop11h 39m

$133

CharlotteCleveland

CLT - CLE

CLTCLE

Charlotte Douglas

Fri 2/6

6:00 am-6:16 pm

1 stop12h 16m

Cleveland Hopkins Intl

Sun 2/8

7:21 pm-8:11 am

1 stop12h 50m

$136

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

Mon 2/9

5:05 pm-12:19 am

1 stop7h 14m

Detroit Metropolitan Wayne County

Tue 2/17

5:09 am-3:55 pm

1 stop10h 46m

$137

CharlestonDetroit

CHS - DTW

CHSDTW

Charleston

Mon 1/26

5:05 pm-12:19 am

1 stop7h 14m

Detroit Metropolitan Wayne County

Fri 1/30

10:08 pm-5:36 pm

2 stops19h 28m

$140

CharlotteColumbus

CLT - CMH

CLTCMH

Charlotte Douglas

Thu 2/5

1:24 pm-11:27 pm

1 stop10h 03m

Columbus

Sat 2/7

5:22 pm-12:40 am

1 stop7h 18m

$145

SavannahDetroit

SAV - DTW

SAVDTW

Savannah/Hilton Head

Fri 1/23

1:17 pm-12:19 am

1 stop11h 02m

Detroit Metropolitan Wayne County

Sun 1/25

10:08 pm-12:22 pm

1 stop14h 14m

$145

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Mon 2/23

5:00 pm-6:51 pm

Nonstop1h 51m

Detroit Metropolitan Wayne County

Mon 3/2

6:05 pm-11:49 pm

1 stop5h 44m

$149

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Thu 2/26

6:00 am-7:52 am

Nonstop1h 52m

Detroit Metropolitan Wayne County

Mon 3/2

4:10 pm-8:38 pm

1 stop4h 28m

$149

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Thu 2/5

9:59 am-3:09 pm

1 stop5h 10m

Detroit Metropolitan Wayne County

Mon 2/9

7:05 am-9:07 am

Nonstop2h 02m

$149

CharlotteDetroit

CLT - DTW

CLTDTW

Charlotte Douglas

Wed 2/25

9:54 am-3:05 pm

1 stop5h 11m

Detroit Metropolitan Wayne County

Sat 2/28

2:15 pm-4:05 pm

Nonstop1h 50m

$149

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Ohio

What is the cheapest month to book a flight from South Carolina to Ohio?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Ohio (average of $40). Flying from South Carolina to Ohio in December is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to OH?

Find hourly flight availability from South Carolina to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 8, 2026.

When flying from South Carolina to Ohio, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 22% versus a flight in the morning.

What is the cheapest day to fly from South Carolina to Ohio?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Ohio. Price data was last updated on January 3, 2026.

Travelers seeking maximum savings on their South Carolina to Ohio flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated January 8, 2026.
Read through reviews of airlines operating flights from South Carolina to Ohio, such as Breeze Airways, Southwest, and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
255 reviews
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Southwest
8.0
Very good
4,250 reviews
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Delta
7.9
Good
8,031 reviews
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,095 reviews
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Allegiant Air
7.2
Good
702 reviews
Breeze Airways
8.2
Very good
255 reviews

Boarding

8.3

Entertainment

6.7

Food

6.7

Comfort

8.2

Crew

8.8

Overall

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Ohio flight route?

    This flight path from South Carolina to Ohio was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Ohio?

    Spirit Airlines, Delta, and Frontier can get you from South Carolina to Ohio in just under 1h 51m. Your travel time can differ by up to 12h. The distance from South Carolina to Ohio is about 500 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Ohio one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $123. However, be on the lookout for offers from Spirit Airlines and Aeromexico, as they are both options that can get you from South Carolina to Ohio for a low price.

  • Can I find deals for flights from South Carolina to Ohio that include hotel bookings?

    Yes. In addition to deals on South Carolina to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Ohio.

  • Can I find deals for business class flights from South Carolina to Ohio?

    Yes. Cheapflights offers flight deals from South Carolina to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Ohio?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Ohio (average of $40). Flying from South Carolina to Ohio in December is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from South Carolina to Ohio

Discover the top 8 airlines that operate flights from South Carolina to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$51Average$152FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$56Average$105FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$76Average$162FlexibilityNo cancel feeOn-time65%
FrontierCheapest$80Average$126FlexibilityNo cancel feeOn-time62%
DeltaCheapest$118Average$319FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$156Average$338FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$196Average$343FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$346FlexibilityNo cancel feeOn-time69%

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