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$113+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/261:59 pm
DTW
-
GSP
2 stops41h 34m
Multiple Airlines
Mon 6/14:10 pm
GSP
-
DTW
1 stop19h 50m
Multiple Airlines
Deal found 4/27$259
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
DTW
-
GSP
1 stop10h 15m
Multiple Airlines
Fri 6/58:28 pm
GSP
-
DTW
1 stop15h 32m
Multiple Airlines
Deal found 4/26$265
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:44 pm
DTW
-
GSP
1 stop18h 49m
Multiple Airlines
Sun 5/318:23 am
GSP
-
DTW
1 stop27h 37m
Multiple Airlines
Deal found 4/24$280
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:29 pm
DTW
-
GSP
1 stop20h 00m
Multiple Airlines
Mon 7/206:19 pm
GSP
-
DTW
2 stops46h 31m
Multiple Airlines
Deal found 4/26$282
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:57 pm
DTW
-
GSP
1 stop19h 34m
Multiple Airlines
Sun 6/148:19 am
GSP
-
DTW
1 stop27h 28m
Multiple Airlines
Deal found 4/28$289
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:29 pm
DTW
-
GSP
1 stop18h 12m
Multiple Airlines
Mon 8/38:13 pm
GSP
-
DTW
2 stops27h 37m
Multiple Airlines
Deal found 4/28$294
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
DTW
-
GSP
1 stop15h 01m
Multiple Airlines
Mon 6/229:51 pm
GSP
-
DTW
1 stop11h 04m
Multiple Airlines
Deal found 4/24$308
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:00 am
DTW
-
GSP
1 stop8h 41m
Multiple Airlines
Mon 7/1312:06 pm
GSP
-
DTW
1 stop11h 44m
Multiple Airlines
Deal found 4/23$309
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:44 pm
DTW
-
GSP
1 stop15h 02m
Multiple Airlines
Thu 6/184:09 pm
GSP
-
DTW
1 stop16h 46m
Multiple Airlines
Deal found 4/27$329

Find flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(Kiwi.com)

One-way from

$113
(Kiwi.com)

Popular in

January

Cheapest in

June

Average price

$464

Good round-trip deal

$439 or less

Good one-way deal

$333 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Greenville flights.
Search Deals
From Detroit Metropolitan Wayne County to Greenville
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Greenville
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($107 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals
Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 5/26

6:10 am-12:10 pm

1 stop6h 00m

Greenville

Mon 6/1

8:10 am-12:20 pm

1 stop4h 10m

$375
Quickest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 5/26

7:59 pm-9:38 pm

Nonstop1h 39m

Greenville

Tue 6/2

6:35 pm-8:24 pm

Nonstop1h 49m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 8/21

8:40 am-10:28 am

Nonstop1h 48m

Greenville

Wed 8/26

7:15 am-9:05 am

Nonstop1h 50m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 8/25

8:40 am-10:28 am

Nonstop1h 48m

Greenville

Sun 8/30

7:15 am-9:05 am

Nonstop1h 50m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 5/29

4:05 pm-5:53 pm

Nonstop1h 48m

Greenville

Fri 6/5

11:43 am-1:29 pm

Nonstop1h 46m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 5/29

4:00 pm-10:35 pm

1 stop6h 35m

Greenville

Tue 6/2

12:50 pm-8:15 pm

2 stops7h 25m

$403

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 5/29

3:35 pm-10:35 pm

2 stops7h 00m

Greenville

Wed 6/3

12:50 pm-10:30 pm

2 stops9h 40m

$408

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 5/29

6:27 pm-11:43 pm

1 stop5h 16m

Greenville

Sun 5/31

11:43 am-1:29 pm

Nonstop1h 46m

$409

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sun 7/12

5:17 am-10:47 am

1 stop5h 30m

Greenville

Mon 7/20

6:47 pm-8:38 pm

Nonstop1h 51m

$409

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 5/29

4:05 pm-5:53 pm

Nonstop1h 48m

Greenville

Tue 6/2

5:05 pm-9:31 pm

1 stop4h 26m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Detroit to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville

What is the cheapest time of day to fly from DTW to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Greenville as you normally would.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated April 29, 2026.
See what other customers who have flown with Southwest and Delta from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,314 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,314 reviews
Southwest
8.0
Very good
4,314 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,465 reviews
Southwest
8.0
Very good
4,314 reviews

Overall

8.0

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    If you book a flight from Detroit to Greenville, you will be flying from Detroit Metropolitan Wayne County to Greenville. Flights to Greenville (GSP) from Detroit Metropolitan Wayne County (DTW) take 1h 39m for a nonstop flight. There are 9 flights from Detroit Metropolitan Wayne County to Greenville per day from 2 airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Southwest and Delta can get you from Detroit Metropolitan Wayne County Airport to Greenville in just under 1h 39m. Your travel time can differ by up to 4h 21m. The distance between Detroit Metropolitan Wayne County Airport and Greenville is about 510 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Greenville round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Greenville round-trip from $293. Another airline that can offer you cheap pricing is Delta. Southwest is currently priced 41% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Greenville on time: WestJet (73%), Virgin Atlantic (71%), SkyWest Airlines (71%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville?

    While on average a flight from Detroit Metropolitan Wayne County Airport to Greenville is generally $431, our data shows the cheapest flight currently is $333. When looking at the most popular route, (Detroit Metropolitan Wayne County - Greenville), you can expect to pay $259 for that flight.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Detroit to Greenville

Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$293Average$323FlexibilityNo cancel feeOn-time63%
DeltaCheapest$399Average$526FlexibilityNo cancel feeOn-timeN/A

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