HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$111+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
Jul 10 — Jul 171
Fri 7/10
Fri 7/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Greenville

Cheapest flights from Detroit to Greenville
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
-
GSP
1 stop20h 57m
Multiple Airlines
Mon 8/244:55 pm
GSP
-
DTW
1 stop20h 12m
Multiple Airlines
Deal found 6/7$211
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:00 am
DTW
-
GSP
1 stop7h 30m
Multiple Airlines
Mon 9/283:18 pm
GSP
-
DTW
1 stop21h 49m
Multiple Airlines
Deal found 6/5$222
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:00 am
DTW
-
GSP
1 stop7h 30m
Multiple Airlines
Fri 9/252:18 pm
GSP
-
DTW
1 stop22h 49m
Multiple Airlines
Deal found 6/5$230
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:00 am
DTW
-
GSP
1 stop20h 57m
Multiple Airlines
Mon 9/712:06 pm
GSP
-
DTW
1 stop25h 01m
Multiple Airlines
Deal found 6/9$232
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:00 am
DTW
-
GSP
1 stop27h 28m
Multiple Airlines
Mon 9/283:18 pm
GSP
-
DTW
1 stop21h 49m
Multiple Airlines
Deal found 6/5$233
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:00 am
DTW
-
GSP
1 stop27h 28m
Multiple Airlines
Fri 9/252:18 pm
GSP
-
DTW
1 stop22h 49m
Multiple Airlines
Deal found 6/5$241
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:12 am
DTW
-
GSP
2 stops10h 21m
Multiple Airlines
Sun 8/23:35 pm
GSP
-
DTW
1 stop21h 20m
Multiple Airlines
Deal found 6/8$242
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:00 am
DTW
-
GSP
1 stop27h 56m
Multiple Airlines
Mon 9/73:18 pm
GSP
-
DTW
1 stop21h 49m
Multiple Airlines
Deal found 6/9$243

Find flight deals from Detroit to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$211
(Kiwi.com)

One-way from

$111
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$409

Good round-trip deal

$509 or less

Good one-way deal

$333 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Greenville flights.
Search Deals
From Detroit Metropolitan Wayne County to Greenville
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Greenville
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals
Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 9/2

12:55 pm-8:55 pm

2 stops8h 00m

Greenville

Mon 9/7

7:00 am-3:10 pm

2 stops8h 10m

$356

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/26

6:25 am-4:45 pm

2 stops10h 20m

Greenville

Sun 8/30

8:40 am-4:45 pm

2 stops8h 05m

$356
Quickest round-trip

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Fri 8/21

7:45 pm-9:26 pm

Nonstop1h 41m

Greenville

Wed 8/26

7:00 pm-8:49 pm

Nonstop1h 49m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 8/25

4:24 pm-6:15 pm

Nonstop1h 51m

Greenville

Sun 8/30

11:10 am-12:58 pm

Nonstop1h 48m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/19

8:25 am-10:15 am

Nonstop1h 50m

Greenville

Mon 8/24

7:15 am-9:02 am

Nonstop1h 47m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/12

7:45 pm-9:26 pm

Nonstop1h 41m

Greenville

Mon 8/17

7:00 pm-8:49 pm

Nonstop1h 49m

$399

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Wed 8/26

6:20 am-11:07 am

1 stop4h 47m

Greenville

Sun 8/30

11:10 am-12:58 pm

Nonstop1h 48m

$409

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Sat 7/18

7:20 am-2:01 pm

1 stop6h 41m

Greenville

Sat 7/25

12:46 pm-2:35 pm

Nonstop1h 49m

$409

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Mon 7/20

8:05 pm-9:47 pm

Nonstop1h 42m

Greenville

Tue 7/28

3:06 pm-8:13 pm

1 stop5h 07m

$409

DetroitGreenville

DTW - GSP

DTWGSP

Detroit Metropolitan Wayne County

Tue 8/11

7:20 am-1:14 pm

1 stop5h 54m

Greenville

Sat 8/15

7:15 am-9:02 am

Nonstop1h 47m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/5

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Detroit to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville

What is the cheapest time of day to fly from DTW to GSP?

Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 10, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Greenville as you normally would.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 10, 2026.
See what other customers who have flown with Southwest and Delta from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,234 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
Southwest
7.9
Good
4,234 reviews
Southwest
7.9
Good
4,234 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
Delta
7.9
Good
8,399 reviews
Southwest
7.9
Good
4,234 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Overall

7.9

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Greenville?

    If you book a flight from Detroit to Greenville, you will be flying from Detroit Metropolitan Wayne County to Greenville. Flights to Greenville (GSP) from Detroit Metropolitan Wayne County (DTW) take 1h 42m for a nonstop flight. There are 11 flights from Detroit Metropolitan Wayne County to Greenville per day from 2 airlines.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Greenville?

    Southwest and Delta can get you from Detroit Metropolitan Wayne County Airport to Greenville in just under 1h 41m. Your travel time can differ by up to 6h 19m. The distance between Detroit Metropolitan Wayne County Airport and Greenville is about 510 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Greenville round-trip?

    Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to Greenville round-trip from $293. Another airline that can offer you cheap pricing is Delta. Southwest is currently priced 46% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Greenville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Greenville on time: KLM (71%), Virgin Atlantic (71%), Korean Air (71%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Greenville?

    While on average a flight from Detroit Metropolitan Wayne County Airport to Greenville is generally $465, our data shows the cheapest flight currently is $333. When looking at the most popular route, (Detroit Metropolitan Wayne County - Greenville), you can expect to pay $226 for that flight.

  • Can I find deals for flights from Detroit to Greenville that include hotel bookings?

    Yes. In addition to deals on Detroit to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Greenville.

  • Can I find deals for business class flights from Detroit to Greenville?

    Yes. Cheapflights offers flight deals from Detroit to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Greenwood
Duncan
Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Detroit to Greenville

Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$293Average$323FlexibilityNo cancel feeOn-time63%
DeltaCheapest$399Average$559FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.