$139+ Cheap flights from Detroit Metropolitan Wayne County Airport to Greenville (DTW - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — GSP
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Greenville
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Cheapest flights from Detroit to GreenvilleExplore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Detroit to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
1 stop15h 25m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 10/23![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Mon 11/98:32 pm -
2 stops22h 10m
Deal found 10/23![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:33 pm -
2 stops11h 59m
Mon 12/72:58 pm -
1 stop20h 23m
Deal found 10/22![Multiple Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:30 am -
1 stop5h 15m
Tue 11/177:05 am -
1 stop6h 15m
Deal found 10/20![Southwest logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Thu 11/1210:12 am -
2 stops13h 25m
Deal found 10/24![Multiple Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/319:29 pm -
1 stop10h 44m
Mon 1/42:42 pm -
1 stop18h 18m
Deal found 10/23![Multiple Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
2 stops8h 40m
Wed 11/1811:20 am -
1 stop6h 40m
Deal found 10/22![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop4h 55m
Thu 11/121:00 pm -
1 stop10h 55m
Deal found 10/23![Southwest logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:50 am -
1 stop12h 22m
Mon 12/142:42 pm -
1 stop20h 39m
Deal found 10/23![Multiple Airlines logo]()
$320
Best flights from Detroit to GreenvilleDiscover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Detroit to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/114:58 pm -
1 stop20h 10m
Mon 1/183:44 pm -
2 stops49h 25m
Deal found 10/24![Multiple Airlines logo]()
$230
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/129:02 am -
1 stop11h 48m
Tue 1/1910:23 am -
1 stop11h 32m
Deal found 10/24![American Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/128:35 am -
2 stops9h 40m
Tue 1/1911:10 am -
2 stops10h 45m
Deal found 10/24![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:25 am -
Nonstop1h 46m
Tue 11/2410:56 am -
Nonstop1h 46m
Deal found 10/20![Delta logo]()
$437
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:30 pm -
2 stops9h 30m
Tue 11/107:05 am -
1 stop6h 15m
Deal found 10/22![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/48:15 pm -
Nonstop1h 43m
Sun 4/117:15 am -
Nonstop1h 51m
Deal found 10/20![Delta logo]()
$437
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:30 am -
2 stops8h 40m
Thu 11/1911:20 am -
2 stops9h 10m
Deal found 10/23![Southwest logo]()
$399
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:24 pm -
Nonstop1h 46m
Mon 11/307:19 pm -
1 stop5h 38m
Deal found 10/20![Delta logo]()
$447
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:40 am -
1 stop5h 50m
Sat 12/58:25 am -
2 stops9h 00m
Deal found 10/24![Southwest logo]()
$419
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:49 pm -
Nonstop1h 44m
Sun 12/67:00 am -
Nonstop1h 51m
Deal found 10/24![Delta logo]()
$453
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:20 am -
1 stop4h 50m
Fri 11/276:40 am -
1 stop6h 05m
Deal found 10/23![Southwest logo]()
$431
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/28:15 pm -
Nonstop1h 43m
Sun 4/47:15 am -
Nonstop1h 51m
Deal found 10/24![Delta logo]()
$453
Last-minute flights from Detroit to GreenvilleDiscover last-minute flight deals from Detroit to Greenville. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Greenville. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Mon 11/98:32 pm -
2 stops22h 10m
Deal found 10/23![Multiple Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Thu 11/1210:12 am -
2 stops13h 25m
Deal found 10/24![Multiple Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop4h 55m
Thu 11/121:00 pm -
1 stop10h 55m
Deal found 10/23![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:30 am -
1 stop5h 15m
Tue 11/177:05 am -
1 stop6h 15m
Deal found 10/20![Southwest logo]()
$294
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:55 am -
2 stops11h 15m
Sat 11/148:25 am -
2 stops9h 05m
Deal found 10/23![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:30 am -
2 stops8h 40m
Wed 11/1811:20 am -
1 stop6h 40m
Deal found 10/22![Southwest logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
1 stop15h 25m
Thu 11/1910:12 am -
2 stops13h 25m
Deal found 10/23![Multiple Airlines logo]()
$226
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:30 am -
1 stop10h 14m
Sat 12/512:14 pm -
1 stop8h 52m
Deal found 10/24![American Airlines logo]()
$321
One-way flights from Detroit to GreenvilleSearch for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Detroit to Greenville. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:29 pm -
1 stop15h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$139
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:50 pm -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/912:44 pm -
3 stops55h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:50 am -
1 stop12h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:15 am -
2 stops22h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/242:55 pm -
2 stops24h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:35 pm -
2 stops35h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$192
Find flight deals from Detroit to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $226 (Kiwi.com) |
One-way from | $139 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $466 |
Good round-trip deal | $447 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Mon 11/9
4:50 pm-9:45 pm
1 stop4h 55m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Sun 11/8
4:29 pm-8:12 pm
2 stops27h 43m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$172
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Tue 12/22
5:15 am-9:50 am
1 stop4h 35m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Sun 11/1
4:29 pm-8:12 pm
2 stops27h 43m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$230
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Mon 1/11
4:58 pm-1:08 pm
1 stop20h 10m
Greenville
Mon 1/18
3:44 pm-5:09 pm
2 stops49h 25m
$230
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 12/23
5:30 pm-9:45 pm
1 stop4h 15m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$237
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
12:45 pm-11:25 pm
1 stop10h 40m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$315
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Wed 11/25
4:25 pm-11:38 pm
1 stop7h 13m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$318
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Tue 1/12
9:02 am-8:50 pm
1 stop11h 48m
Greenville
Tue 1/19
10:23 am-9:55 pm
1 stop11h 32m
$321
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Tue 1/12
8:35 am-6:15 pm
2 stops9h 40m
Greenville
Tue 1/19
11:10 am-9:55 pm
2 stops10h 45m
$387
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Detroit to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Greenville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Detroit with our price prediction graph.
DTW-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Greenville
Prices
Airlines
What is the cheapest time of day to fly from DTW to GSP?
Find hourly flight availability from Detroit to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit Metropolitan Wayne County Airport to Greenville as you normally would.
How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Greenville?
Airfare is below average for this route at the moment.
Detroit Metropolitan Wayne County Airport to Greenville flights typically cost between $455 and $576 in November.The cheapest round-trip price found within the last 5 days was $226 on Multiple Airlines (Nov 18-Nov 19).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 25, 2026.
See what other customers who have flown with Southwest and Delta from Detroit Metropolitan Wayne County Airport to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Entertainment
7.4
Food
7.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Detroit to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Detroit and Greenville flights
Browse other Detroit and Greenville flight options. Last updated on October 25, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Detroit to Greenville
Discover the top 2 airlines that operate flights from Detroit to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$271 | Average$391 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$399 | Average$498 | FlexibilityNo cancel fee | On-timeN/A |