South Carolina

$36+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
Jul 17 — Jul 241
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Cheap flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 17, 2026.

This Jettzy deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jettzy is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:14 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Tue 8/256:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/12$77
This Breeze Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:50 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Tue 8/256:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$78
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:03 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Sun 9/66:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$81
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:50 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Sun 9/66:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$91
This Breeze Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:50 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Sun 8/236:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$98
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:03 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Tue 9/157:05 am
CHS
-
CAK
Nonstop1h 53m
Breeze Airways
Deal found 6/16$101
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:14 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Thu 8/206:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/15$102
This Super.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:39 pm
CLE
-
MYR
Nonstop1h 45m
Frontier
Thu 9/178:19 pm
MYR
-
CLE
Nonstop1h 49m
Frontier
Deal found 6/14$103
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:39 am
CAK
-
MYR
Nonstop1h 38m
Allegiant Air
Thu 8/131:07 pm
MYR
-
CAK
Nonstop1h 42m
Allegiant Air
Deal found 6/13$105
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:39 am
CAK
-
MYR
Nonstop1h 38m
Multiple Airlines
Sun 8/236:25 pm
MYR
-
CAK
Nonstop1h 43m
Multiple Airlines
Deal found 6/15$106
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:50 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Thu 7/306:00 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$107
This Breeze Airways deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:50 pm
CAK
-
CHS
Nonstop1h 46m
Breeze Airways
Sat 9/510:46 am
CHS
-
CAK
Nonstop1h 48m
Breeze Airways
Deal found 6/16$108

Find flight deals from Ohio to South Carolina

Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated June 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$77
(Kiwi.com)

One-way from

$36
(CheapOair)

Popular in

March

Cheapest in

August

Average price

$237

Good round-trip deal

$90 or less

Good one-way deal

$50 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Myrtle Beach Intl flights.
From Ohio to South Carolina
One-way flight from Ohio to South Carolina
Highest demand for flights based on searches. 14% potential increase in price ($42 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in June 2026
Price to beat on a round-trip flight from Ohio to South Carolina.
Price to beat on a one-way flight from Ohio to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Sat 8/29

3:50 pm-5:36 pm

Nonstop1h 46m

Charleston

Tue 9/1

6:00 am-7:48 am

Nonstop1h 48m

$78

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 8/20

7:03 pm-8:49 pm

Nonstop1h 46m

Charleston

Mon 8/24

10:46 am-12:34 pm

Nonstop1h 48m

$118

AkronSavannah

CAK - SAV

CAKSAV

Akron/Canton

Sun 10/4

2:34 pm-4:34 pm

Nonstop2h 00m

Savannah/Hilton Head

Thu 10/8

9:39 pm-11:39 pm

Nonstop2h 00m

$133
Quickest round-trip

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Thu 8/20

9:41 am-11:21 am

Nonstop1h 40m

Myrtle Beach Intl

Sun 8/23

6:25 pm-8:08 pm

Nonstop1h 43m

$138

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Thu 8/27

9:41 am-11:21 am

Nonstop1h 40m

Myrtle Beach Intl

Tue 9/1

10:38 am-12:21 pm

Nonstop1h 43m

$138

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Fri 8/28

10:53 am-12:33 pm

Nonstop1h 40m

Myrtle Beach Intl

Mon 8/31

8:30 am-10:13 am

Nonstop1h 43m

$143

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Mon 9/14

8:00 am-9:37 am

Nonstop1h 37m

Myrtle Beach Intl

Fri 9/18

10:17 am-12:09 pm

Nonstop1h 52m

$143

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Sat 8/15

1:19 pm-2:59 pm

Nonstop1h 40m

Myrtle Beach Intl

Fri 8/21

8:30 am-10:13 am

Nonstop1h 43m

$148

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 11/5

8:22 pm-10:10 pm

Nonstop1h 48m

Charleston

Sun 11/8

7:05 am-8:58 am

Nonstop1h 53m

$173

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 10/15

8:22 pm-10:10 pm

Nonstop1h 48m

Charleston

Tue 10/20

7:05 am-8:58 am

Nonstop1h 53m

$198

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South Carolina

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, December is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $46). Flying from Ohio to South Carolina in November is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 17, 2026.

Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Ohio to South Carolina by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Ohio to South Carolina?

How far ahead should I book a flight from Ohio to South Carolina?

The price you pay for your flight from Ohio to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest day to fly from Ohio to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on June 13, 2026.

Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 17, 2026.
Read reviews from past customers who have flown Breeze Airways,Southwest, andDelta from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Overall

8.2

Crew

8.8

Boarding

8.3

Entertainment

6.6

Comfort

8.2

Food

6.7

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Ohio to South Carolina?

    There are many flights that can get you from Ohio to South Carolina in 1h 46m. Fly via Breeze Airways, Southwest, or Delta to get the fastest option. Ohio and South Carolina are separated by a distance of 559 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $39. However, be on the lookout for offers from Frontier and Allegiant Air, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, December is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $46). Flying from Ohio to South Carolina in November is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Ohio to South Carolina

Discover the top 7 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$49Average$164FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$55Average$146FlexibilityNo cancel feeOn-time88%
FrontierCheapest$67Average$138FlexibilityNo cancel feeOn-time62%
DeltaCheapest$88Average$339FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$128Average$360FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$195Average$383FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$370FlexibilityNo cancel feeOn-time63%

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