$42+ Cheap flights from Ohio to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
Jun 7 — Jun 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Ohio to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Ohio to South CarolinaExplore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:32 pm
CAK
- SAV
Nonstop1h 47m
Allegiant Air
Sun 7/128:00 am
SAV
- CAK
Nonstop1h 48m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$85
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:32 pm
CAK
- SAV
Nonstop1h 42m
Allegiant Air
Sun 5/248:00 am
SAV
- CAK
Nonstop1h 47m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$89
This Super.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:00 pm
CLE
- MYR
Nonstop1h 46m
Frontier
Thu 5/143:31 pm
MYR
- CLE
Nonstop1h 52m
Frontier
Deal found 5/2![Frontier logo]()
$93
This Cheapflightsfares deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:00 pm
CAK
- SAV
Nonstop1h 45m
Allegiant Air
Thu 7/308:15 am
SAV
- CAK
Nonstop1h 48m
Allegiant Air
Deal found 5/6![Allegiant Air logo]()
$94
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/171:00 pm
CLE
- MYR
Nonstop1h 46m
Frontier
Thu 5/213:31 pm
MYR
- CLE
Nonstop1h 52m
Frontier
Deal found 5/2![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Sun 5/241:00 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/5![Allegiant Air logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/102:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Thu 5/145:01 pm
MYR
- CAK
Nonstop1h 41m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$99
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:00 pm
CAK
- SAV
Nonstop1h 43m
Allegiant Air
Thu 6/411:15 am
SAV
- CAK
Nonstop1h 49m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:38 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Thu 7/231:06 pm
MYR
- CAK
Nonstop1h 39m
Allegiant Air
Deal found 5/6![Allegiant Air logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Thu 5/211:00 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:53 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Thu 8/61:07 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/5![Allegiant Air logo]()
$102
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:00 pm
CAK
- SAV
Nonstop1h 45m
Allegiant Air
Mon 7/2010:56 am
SAV
- CAK
Nonstop1h 48m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$103
Best flights from Ohio to South CarolinaDiscover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
Discover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 8, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:41 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Tue 9/110:38 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$111
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:10 am
PIT
- MYR
2 stops9h 10m
Southwest
Tue 8/112:25 pm
MYR
- PIT
1 stop3h 10m
Southwest
Deal found 5/6![Southwest logo]()
$274
This Breeze Airways deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:34 pm
CAK
- SAV
Nonstop2h 00m
Breeze Airways
Thu 10/89:39 pm
SAV
- CAK
Nonstop2h 00m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$138
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:13 am
PIT
- CHS
1 stop7h 03m
Delta
Sat 7/188:05 am
CHS
- PIT
1 stop4h 37m
Delta
Deal found 5/4![Delta logo]()
$279
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:35 pm
CAK
- MYR
Nonstop1h 38m
Multiple Airlines
Fri 7/179:45 am
MYR
- CAK
Nonstop1h 43m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:00 am
CAK
- SAV
1 stop6h 16m
United Airlines
Thu 6/46:10 pm
SAV
- CAK
1 stop5h 39m
United Airlines
Deal found 5/4![United Airlines logo]()
$384
This Breeze Airways deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/29:41 am
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Thu 8/66:25 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$178
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:08 pm
CLE
- CLT
Nonstop1h 39m
American Airlines
Mon 7/138:44 pm
CLT
- CLE
Nonstop1h 38m
American Airlines
Deal found 5/7![American Airlines logo]()
$393
This Breeze Airways deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/315:47 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Wed 6/31:30 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$223
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:50 pm
PIT
- CHS
1 stop7h 00m
Southwest
Mon 6/297:35 pm
CHS
- PIT
1 stop3h 55m
Southwest
Deal found 5/3![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:55 pm
PIT
- CHS
1 stop5h 11m
Delta
Fri 6/125:10 am
CHS
- PIT
1 stop5h 35m
Delta
Deal found 5/5![Delta logo]()
$279
This Breeze Airways deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Mon 6/89:45 am
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$223
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:25 pm
PIT
- CHS
1 stop4h 20m
Southwest
Sat 7/185:30 am
CHS
- PIT
1 stop4h 45m
Southwest
Deal found 5/5![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:29 am
PIT
- CHS
1 stop5h 41m
Delta
Sat 6/136:00 am
CHS
- PIT
1 stop5h 45m
Delta
Deal found 5/3![Delta logo]()
$279
This Breeze Airways deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Thu 8/66:25 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$233
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:50 pm
PIT
- CHS
1 stop4h 09m
Delta
Wed 6/36:38 pm
CHS
- PIT
1 stop4h 00m
Delta
Deal found 5/3![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:50 pm
PIT
- CHS
1 stop7h 00m
Southwest
Tue 7/282:10 pm
CHS
- PIT
2 stops7h 35m
Southwest
Deal found 5/6![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:01 pm
PIT
- CHS
1 stop3h 48m
Delta
Fri 6/53:45 pm
CHS
- PIT
1 stop7h 13m
Delta
Deal found 5/6![Delta logo]()
$284
This Breeze Airways deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Sat 8/18:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$238
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:40 am
PIT
- CHS
1 stop4h 20m
Southwest
Fri 6/54:45 pm
CHS
- PIT
1 stop5h 45m
Southwest
Deal found 5/7![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:00 am
CLE
- MYR
1 stop5h 12m
United Airlines
Sun 5/246:30 pm
MYR
- CLE
1 stop5h 28m
United Airlines
Deal found 5/5![United Airlines logo]()
$387
This Breeze Airways deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/41:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Sun 7/126:25 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$238
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:09 am
PIT
- CHS
1 stop7h 06m
Delta
Sun 6/77:59 pm
CHS
- PIT
1 stop4h 56m
Delta
Deal found 5/7![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:00 am
CAK
- SAV
1 stop6h 16m
United Airlines
Tue 6/93:14 pm
SAV
- CAK
1 stop5h 14m
United Airlines
Deal found 5/5![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:50 am
PIT
- CHS
2 stops6h 50m
Southwest
Thu 6/44:10 pm
CHS
- PIT
2 stops8h 40m
Southwest
Deal found 5/6![Southwest logo]()
$299
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:50 pm
PIT
- MYR
1 stop4h 08m
Delta
Mon 6/87:57 pm
MYR
- PIT
1 stop4h 58m
Delta
Deal found 5/4![Delta logo]()
$289
This Breeze Airways deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/271:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Sat 7/48:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$243
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:45 pm
PIT
- MYR
1 stop5h 40m
Southwest
Sat 6/207:50 am
MYR
- PIT
1 stop5h 20m
Southwest
Deal found 5/7![Southwest logo]()
$301
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/204:25 pm
CLE
- MYR
1 stop4h 15m
Southwest
Tue 6/237:05 pm
MYR
- CLE
1 stop3h 30m
Southwest
Deal found 5/3![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:40 pm
CLE
- MYR
1 stop7h 10m
Delta
Tue 7/711:00 am
MYR
- CLE
1 stop8h 03m
Delta
Deal found 5/2![Delta logo]()
$309
Last-minute flights from Ohio to South CarolinaDiscover last-minute flight deals from Ohio to South Carolina. Data last updated May 8, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to South Carolina. Data last updated May 8, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/101:00 pm
CLE
- MYR
Nonstop1h 46m
Frontier
Thu 5/143:31 pm
MYR
- CLE
Nonstop1h 52m
Frontier
Deal found 5/2![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/102:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Thu 5/145:01 pm
MYR
- CAK
Nonstop1h 41m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$99
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:32 pm
CAK
- SAV
Nonstop1h 42m
Allegiant Air
Sun 5/248:00 am
SAV
- CAK
Nonstop1h 47m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$89
This Frontier deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/171:00 pm
CLE
- MYR
Nonstop1h 46m
Frontier
Thu 5/213:31 pm
MYR
- CLE
Nonstop1h 52m
Frontier
Deal found 5/2![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Sun 5/241:00 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/5![Allegiant Air logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Thu 5/211:00 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$101
This Cheapflightsfares deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:32 pm
CAK
- SAV
Nonstop1h 42m
Allegiant Air
Thu 5/218:00 am
SAV
- CAK
Nonstop1h 47m
Allegiant Air
Deal found 5/6![Allegiant Air logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Thu 5/281:00 pm
MYR
- CAK
Nonstop1h 42m
Allegiant Air
Deal found 5/5![Allegiant Air logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:10 pm
CAK
- MYR
Nonstop1h 40m
Multiple Airlines
Thu 5/281:00 pm
MYR
- CAK
Nonstop1h 42m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:10 pm
CAK
- MYR
Nonstop1h 40m
Multiple Airlines
Sun 5/241:00 pm
MYR
- CAK
Nonstop1h 42m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/201:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Wed 5/208:44 pm
MYR
- CAK
Nonstop1h 43m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$100
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:00 pm
CAK
- SAV
Nonstop1h 43m
Allegiant Air
Thu 6/411:15 am
SAV
- CAK
Nonstop1h 49m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$99
One-way flights from Ohio to South CarolinaSearch for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
Search for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 8, 2026.
This Mytrip deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:53 am
CAK
- MYR
Nonstop1h 38m
Allegiant Air
Deal found 5/5![Allegiant Air logo]()
$42
This Priceline deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:02 pm
CLE
- MYR
Nonstop1h 45m
Frontier
Deal found 5/6![Frontier logo]()
$42
This Frontier deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:02 pm
CLE
- MYR
Nonstop1h 45m
Frontier
Deal found 5/4![Frontier logo]()
$47
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:25 pm
PIT
- MYR
Nonstop1h 38m
Breeze Airways
Deal found 5/5![Breeze Airways logo]()
$49
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/172:38 pm
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Deal found 5/6![Allegiant Air logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$50
This Cheapflightsfares deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:00 pm
CAK
- SAV
Nonstop1h 45m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$52
This Booking.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 5/4![Breeze Airways logo]()
$53
This Priceline deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:00 pm
CLE
- MYR
Nonstop1h 46m
Frontier
Deal found 5/5![Frontier logo]()
$53
This Super.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:19 pm
CAK
- MYR
Nonstop1h 40m
Breeze Airways
Deal found 5/3![Breeze Airways logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:37 am
CAK
- MYR
Nonstop1h 33m
Allegiant Air
Deal found 5/7![Allegiant Air logo]()
$55
This Cheapflightsfares deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:22 pm
PIT
- MYR
Nonstop1h 27m
Allegiant Air
Deal found 5/4![Allegiant Air logo]()
$55
Find flight deals from Ohio to South Carolina
Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated May 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $85 (Cheapflightsfares) |
One-way from | $42 (Mytrip) |
Popular in | March |
Cheapest in | August |
Average price | $132 |
Good round-trip deal | $68 or less |
Good one-way deal | $41 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Thu 8/27
9:41 am-11:21 am
Nonstop1h 40m
Myrtle Beach Intl
Tue 9/1
10:38 am-12:21 pm
Nonstop1h 43m
$111
AkronSavannah
CAK - SAV
CAKSAV
Akron/Canton
Sun 10/4
2:34 pm-4:34 pm
Nonstop2h 00m
Savannah/Hilton Head
Thu 10/8
9:39 pm-11:39 pm
Nonstop2h 00m
$138
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Sun 8/2
9:41 am-11:21 am
Nonstop1h 40m
Myrtle Beach Intl
Thu 8/6
6:25 pm-8:08 pm
Nonstop1h 43m
$178
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Sun 5/31
5:47 pm-7:31 pm
Nonstop1h 44m
Charleston
Wed 6/3
1:30 pm-3:14 pm
Nonstop1h 44m
$223
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Wed 6/3
1:19 pm-2:59 pm
Nonstop1h 40m
Myrtle Beach Intl
Mon 6/8
9:45 am-11:28 am
Nonstop1h 43m
$223
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Sat 8/1
1:19 pm-2:59 pm
Nonstop1h 40m
Myrtle Beach Intl
Thu 8/6
6:25 pm-8:08 pm
Nonstop1h 43m
$233
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Sat 7/25
1:19 pm-2:59 pm
Nonstop1h 40m
Myrtle Beach Intl
Sat 8/1
8:44 pm-10:27 pm
Nonstop1h 43m
$238
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Sat 7/4
1:19 pm-2:59 pm
Nonstop1h 40m
Myrtle Beach Intl
Sun 7/12
6:25 pm-8:08 pm
Nonstop1h 43m
$238
AkronMyrtle Beach
CAK - MYR
CAKMYR
Akron/Canton
Sat 6/27
1:19 pm-2:59 pm
Nonstop1h 40m
Myrtle Beach Intl
Sat 7/4
8:44 pm-10:27 pm
Nonstop1h 43m
$243
PittsburghMyrtle Beach
PIT - MYR
PITMYR
Pittsburgh
Wed 8/5
10:10 am-7:20 pm
2 stops9h 10m
Myrtle Beach Intl
Tue 8/11
2:25 pm-5:35 pm
1 stop3h 10m
$274
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
CAK-MYR
CLE-MYR
PIT-MYR
CAK-SAV
CLE-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to South Carolina
USOH-USSC
CAK-MYR
CLE-MYR
PIT-MYR
CAK-SAV
How far ahead should I book a flight from Ohio to South Carolina?
The price you pay for your flight from Ohio to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 47 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Ohio to South Carolina?
Currently, December is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $46). Flying from Ohio to South Carolina in November is currently the most expensive (average of $415). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to SC?
Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 8, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 21% on flights from Ohio to South Carolina by exploring options for tickets in the evening.
What is the cheapest day to fly from Ohio to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Ohio to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 8, 2026.
Read reviews from past customers who have flown Breeze Airways,Delta, andAllegiant Air from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Crew
8.7
Food
6.6
Overall
8.1
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Ohio to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to South Carolina by cabin class
Find flights from Ohio to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and South Carolina flights
Browse other Ohio and South Carolina flight options. Last updated on May 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Ohio after your stay in South Carolina
Ohio to South Carolina flights
Consider these flights traveling from Ohio to South Carolina.
Top 8 airlines flying from Ohio to South Carolina
Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$46 | Average$163 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$56 | Average$140 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$57 | Average$128 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$64 | Average$163 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$118 | Average$328 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$128 | Average$363 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$158 | Average$365 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$196 | Average$363 | FlexibilityNo cancel fee | On-time63% |