$37+ Cheap flights from Ohio to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Ohio to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Ohio to South CarolinaExplore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:27 pm -
Nonstop1h 43m
Thu 12/103:00 pm -
Nonstop1h 47m
Deal found 11/4![Allegiant Air logo]()
$67
This Booking.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:27 pm -
Nonstop1h 43m
Sun 12/67:00 am -
Nonstop1h 51m
Deal found 10/31![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:22 pm -
Nonstop1h 43m
Sun 12/136:45 am -
Nonstop1h 44m
Deal found 11/3![Breeze Airways logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:37 pm -
Nonstop1h 43m
Thu 12/36:45 am -
Nonstop1h 44m
Deal found 11/4![Breeze Airways logo]()
$97
This Breeze Airways deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:22 pm -
Nonstop1h 48m
Thu 12/107:05 am -
Nonstop1h 53m
Deal found 11/2![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:57 pm -
Nonstop1h 39m
Thu 12/103:00 pm -
Nonstop1h 47m
Deal found 11/3![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
Nonstop1h 37m
Sat 12/1210:08 am -
Nonstop1h 52m
Deal found 11/3![Breeze Airways logo]()
$106
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:58 am -
Nonstop1h 39m
Thu 11/193:04 pm -
Nonstop1h 45m
Deal found 10/31![Allegiant Air logo]()
$106
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:57 pm -
Nonstop1h 39m
Sun 12/137:00 am -
Nonstop1h 51m
Deal found 11/4![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:22 pm -
Nonstop1h 48m
Tue 1/57:05 am -
Nonstop1h 53m
Deal found 11/3![Breeze Airways logo]()
$118
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
Nonstop1h 37m
Mon 12/710:17 am -
Nonstop1h 52m
Deal found 11/2![Breeze Airways logo]()
$127
This Breeze Airways deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:22 pm -
Nonstop1h 48m
Thu 12/107:05 am -
Nonstop1h 53m
Deal found 10/31![Breeze Airways logo]()
$128
Best flights from Ohio to South CarolinaDiscover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/148:22 pm -
Nonstop1h 48m
Tue 1/197:05 am -
Nonstop1h 53m
Deal found 10/31![Breeze Airways logo]()
$91
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/297:10 am -
2 stops8h 10m
Mon 2/15:35 pm -
1 stop4h 35m
Deal found 11/2![Southwest logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:32 pm -
Nonstop1h 20m
Mon 12/148:52 pm -
3 stops15h 06m
Deal found 11/4![Multiple Airlines logo]()
$168
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:04 pm -
1 stop4h 58m
Sat 1/308:10 am -
1 stop6h 42m
Deal found 11/4![Delta logo]()
$177
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/178:22 pm -
Nonstop1h 48m
Sun 1/247:05 am -
Nonstop1h 53m
Deal found 11/4![Breeze Airways logo]()
$103
This Breeze Airways deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/78:22 pm -
Nonstop1h 48m
Sun 1/107:05 am -
Nonstop1h 53m
Deal found 10/31![Breeze Airways logo]()
$113
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:13 am -
1 stop7h 44m
Tue 12/86:50 am -
1 stop5h 31m
Deal found 11/4![American Airlines logo]()
$279
This Breeze Airways deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/148:22 pm -
Nonstop1h 48m
Tue 2/167:05 am -
Nonstop1h 53m
Deal found 11/3![Breeze Airways logo]()
$118
This JetBlue deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
1 stop5h 56m
Tue 2/22:00 pm -
1 stop7h 11m
Deal found 11/1![JetBlue logo]()
$303
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:15 am -
1 stop5h 48m
Sat 12/56:45 am -
2 stops14h 16m
Deal found 11/3![United Airlines logo]()
$322
This Breeze Airways deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:22 pm -
Nonstop1h 48m
Thu 12/107:05 am -
Nonstop1h 53m
Deal found 10/31![Breeze Airways logo]()
$128
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:04 pm -
1 stop4h 58m
Mon 2/19:47 am -
1 stop5h 25m
Deal found 11/4![Delta logo]()
$177
This Breeze Airways deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:13 pm -
Nonstop1h 46m
Sun 2/74:47 pm -
Nonstop1h 46m
Deal found 11/1![Breeze Airways logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:32 pm -
Nonstop1h 20m
Mon 11/234:27 pm -
Nonstop1h 25m
Deal found 11/2![Breeze Airways logo]()
$140
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:00 am -
1 stop4h 15m
Thu 12/105:10 am -
1 stop6h 15m
Deal found 11/4![Delta logo]()
$207
This Breeze Airways deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/34:36 pm -
Nonstop1h 48m
Sat 3/61:29 pm -
Nonstop1h 53m
Deal found 11/1![Breeze Airways logo]()
$158
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:20 am -
2 stops7h 50m
Tue 12/88:05 am -
1 stop4h 05m
Deal found 10/31![Southwest logo]()
$284
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:10 am -
1 stop4h 17m
Mon 11/308:35 pm -
1 stop3h 22m
Deal found 11/4![American Airlines logo]()
$298
This JetBlue deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:00 am -
1 stop6h 03m
Sun 12/131:53 pm -
1 stop5h 39m
Deal found 11/4![JetBlue logo]()
$303
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:05 am -
1 stop6h 10m
Tue 12/110:27 am -
1 stop3h 39m
Deal found 11/4![Delta logo]()
$258
This Southwest deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:50 am -
1 stop4h 15m
Mon 1/258:00 am -
2 stops12h 50m
Deal found 10/31![Southwest logo]()
$290
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:10 pm -
2 stops9h 49m
Thu 12/103:30 pm -
2 stops8h 29m
Deal found 11/4![United Airlines logo]()
$327
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:55 am -
1 stop5h 19m
Sat 12/1210:08 am -
Nonstop1h 52m
Deal found 11/4![Breeze Airways logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:57 pm -
2 stops44h 35m
Tue 12/811:28 am -
1 stop5h 58m
Deal found 11/4![Multiple Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/144:25 pm -
1 stop4h 41m
Sat 2/208:20 am -
1 stop4h 07m
Deal found 11/1![Delta logo]()
$271
This JetBlue deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:00 am -
1 stop6h 03m
Mon 12/71:53 pm -
1 stop5h 39m
Deal found 11/1![JetBlue logo]()
$334
This Breeze Airways deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/174:36 pm -
Nonstop1h 48m
Wed 3/242:01 pm -
Nonstop1h 49m
Deal found 10/31![Breeze Airways logo]()
$173
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:00 am -
1 stop4h 10m
Thu 12/247:05 am -
1 stop5h 25m
Deal found 11/2![Southwest logo]()
$308
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:00 am -
1 stop5h 00m
Mon 12/76:00 am -
1 stop7h 18m
Deal found 11/4![United Airlines logo]()
$346
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:00 pm -
1 stop5h 49m
Mon 12/77:10 pm -
1 stop4h 49m
Deal found 10/31![Delta logo]()
$279
Last-minute flights from Ohio to South CarolinaDiscover last-minute flight deals from Ohio to South Carolina. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to South Carolina. Data last updated November 5, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:58 am -
Nonstop1h 39m
Thu 11/193:04 pm -
Nonstop1h 45m
Deal found 10/31![Allegiant Air logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:37 pm -
Nonstop1h 43m
Thu 12/36:45 am -
Nonstop1h 44m
Deal found 11/4![Breeze Airways logo]()
$97
This Booking.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:27 pm -
Nonstop1h 43m
Sun 12/67:00 am -
Nonstop1h 51m
Deal found 10/31![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
Nonstop1h 37m
Sat 12/1210:08 am -
Nonstop1h 52m
Deal found 11/3![Breeze Airways logo]()
$106
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
Nonstop1h 37m
Mon 12/710:17 am -
Nonstop1h 52m
Deal found 11/2![Breeze Airways logo]()
$127
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:27 pm -
Nonstop1h 43m
Thu 12/103:00 pm -
Nonstop1h 47m
Deal found 11/4![Allegiant Air logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:22 pm -
Nonstop1h 43m
Sun 12/136:45 am -
Nonstop1h 44m
Deal found 11/3![Breeze Airways logo]()
$96
This Breeze Airways deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:22 pm -
Nonstop1h 48m
Thu 12/107:05 am -
Nonstop1h 53m
Deal found 10/31![Breeze Airways logo]()
$128
This Breeze Airways deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:22 pm -
Nonstop1h 48m
Thu 12/107:05 am -
Nonstop1h 53m
Deal found 11/2![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:57 pm -
Nonstop1h 39m
Thu 12/103:00 pm -
Nonstop1h 47m
Deal found 11/3![Multiple Airlines logo]()
$105
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:57 pm -
Nonstop1h 39m
Sun 12/137:00 am -
Nonstop1h 51m
Deal found 11/4![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:22 pm -
Nonstop1h 48m
Tue 1/57:05 am -
Nonstop1h 53m
Deal found 11/3![Breeze Airways logo]()
$118
One-way flights from Ohio to South CarolinaSearch for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1312:27 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Allegiant Air logo]()
$37
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:22 pm -
Nonstop1h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Breeze Airways logo]()
$43
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:37 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Breeze Airways logo]()
$48
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:22 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Breeze Airways logo]()
$50
This Super.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1511:58 am -
Nonstop1h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Allegiant Air logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:22 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:57 pm -
Nonstop1h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Breeze Airways logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:57 pm -
Nonstop1h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Breeze Airways logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:22 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:37 pm -
Nonstop1h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Breeze Airways logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:25 pm -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Breeze Airways logo]()
$73
Find flight deals from Ohio to South Carolina
Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $67 (CheapOair) |
One-way from | $37 (CheapOair) |
Popular in | March |
Cheapest in | April |
Average price | $386 |
Good round-trip deal | $108 or less |
Good one-way deal | $53 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
AkronMyrtle Beach
CAK Akron/Canton - MYR Myrtle Beach Intl
CAKMYR
Akron/Canton
Fri 12/4
8:00 am-9:37 am
Nonstop1h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$53
AkronMyrtle Beach
CAK Akron/Canton - MYR Myrtle Beach Intl
CAKMYR
Akron/Canton
Wed 11/18
12:25 pm-2:02 pm
Nonstop1h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$78
ColumbusGreenville
CMH Columbus - GSP Greenville
CMHGSP
Columbus
Wed 12/9
1:24 pm-9:32 am
2 stops20h 08m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
CincinnatiCharleston
CVG Cincinnati Cinci./N. Kentucky - CHS Charleston
CVGCHS
Cincinnati Cinci./N. Kentucky
Fri 11/27
5:50 am-10:20 am
1 stop4h 30m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
CincinnatiCharleston
CVG Cincinnati Cinci./N. Kentucky - CHS Charleston
CVGCHS
Cincinnati Cinci./N. Kentucky
Wed 11/25
8:53 am-3:20 pm
1 stop6h 27m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$80
CincinnatiCharleston
CVG Cincinnati Cinci./N. Kentucky - CHS Charleston
CVGCHS
Cincinnati Cinci./N. Kentucky
Fri 12/4
6:45 pm-12:04 am
1 stop5h 19m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$89
CincinnatiCharleston
CVG Cincinnati Cinci./N. Kentucky - CHS Charleston
CVGCHS
Cincinnati Cinci./N. Kentucky
Fri 1/29
7:04 pm-10:53 pm
1 stop3h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$89
ClevelandGreenville
CLE Cleveland Hopkins Intl - GSP Greenville
CLEGSP
Cleveland Hopkins Intl
Wed 11/18
8:18 pm-9:32 am
2 stops13h 14m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$91
AkronCharleston
CAK Akron/Canton - CHS Charleston
CAKCHS
Akron/Canton
Thu 1/14
8:22 pm-10:10 pm
Nonstop1h 48m
Charleston
Tue 1/19
7:05 am-8:58 am
Nonstop1h 53m
$91
ClevelandGreenville
CLE Cleveland Hopkins Intl - GSP Greenville
CLEGSP
Cleveland Hopkins Intl
Thu 11/12
9:18 pm-8:13 am
1 stop10h 55m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$92
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
CAK-MYR
CMH-GSP
CVG-CHS
CLE-CHS
CLE-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to South Carolina
USOH-USSC
CAK-MYR
CMH-GSP
CVG-CHS
CLE-CHS
What is the cheapest month to book a flight from Ohio to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $178). Flying from Ohio to South Carolina in December is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to SC?
Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 33% on flights from Ohio to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Ohio to South Carolina?
Airfare is below average for this route at the moment.
Ohio to South Carolina flights typically cost between $321 and $440 in January.The cheapest round-trip price found within the last 5 days was $185 on Multiple Airlines (Jan 4-Feb 2).
How far ahead should I book a flight from Ohio to South Carolina?
The price you pay for your flight from Ohio to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Ohio to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on October 31, 2026.
Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Wednesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 5, 2026.
Read reviews from past customers who have flown Breeze Airways,Delta, andAllegiant Air from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Boarding
8.4
Food
6.7
Comfort
8.2
Crew
8.8
Entertainment
6.8
Overall
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Related info for your journey
Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Ohio to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to South Carolina by cabin class
Find flights from Ohio to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and South Carolina flights
Browse other Ohio and South Carolina flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Ohio after your stay in South Carolina
Ohio to South Carolina flights
Consider these flights traveling from Ohio to South Carolina.
Top 8 airlines flying from Ohio to South Carolina
Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$181 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$73 | Average$159 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$81 | Average$173 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$88 | Average$368 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$158 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$169 | Average$402 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$186 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$334 | FlexibilityNo cancel fee | On-time62% |