$29+ Cheap flights from Ohio to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — CHS
Oct 17 — Oct 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Ohio to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Ohio to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Ohio to South CarolinaExplore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:43 pm -
Nonstop1h 54m
Thu 12/1010:58 am -
Nonstop1h 55m
Deal found 9/15![Allegiant Air logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:25 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$97
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:05 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/14![Allegiant Air logo]()
$98
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:13 pm -
Nonstop1h 41m
Thu 11/510:56 am -
Nonstop1h 48m
Deal found 9/15![Allegiant Air logo]()
$103
This Orbitz deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:20 pm -
Nonstop1h 37m
Fri 11/610:17 am -
Nonstop1h 52m
Deal found 9/13![Multiple Airlines logo]()
$106
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:43 pm -
Nonstop1h 54m
Sun 12/610:58 am -
Nonstop1h 55m
Deal found 9/14![Allegiant Air logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:25 pm -
Nonstop1h 37m
Thu 10/222:32 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:20 pm -
Nonstop1h 37m
Wed 11/49:53 am -
Nonstop1h 52m
Deal found 9/14![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:25 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/14![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:00 am -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/15![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:44 pm -
Nonstop1h 38m
Mon 11/165:28 pm -
Nonstop1h 36m
Deal found 9/13![Breeze Airways logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:44 pm -
Nonstop1h 38m
Fri 10/235:28 pm -
Nonstop1h 36m
Deal found 9/16![Breeze Airways logo]()
$152
Best flights from Ohio to South CarolinaDiscover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Ohio to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:35 am -
Nonstop2h 00m
Thu 10/19:44 pm -
Nonstop2h 00m
Deal found 9/14![Breeze Airways logo]()
$128
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/173:55 pm -
1 stop3h 40m
Wed 10/215:00 pm -
1 stop4h 15m
Deal found 9/16![Southwest logo]()
$235
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:08 pm -
1 stop8h 34m
Tue 10/278:44 am -
1 stop8h 05m
Deal found 9/16![JetBlue logo]()
$266
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:55 pm -
Nonstop2h 09m
Mon 11/165:30 am -
1 stop3h 57m
Deal found 9/15![Delta logo]()
$289
This Breeze Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:34 pm -
Nonstop2h 00m
Thu 10/89:44 pm -
Nonstop2h 00m
Deal found 9/12![Breeze Airways logo]()
$148
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:47 pm -
1 stop7h 27m
Mon 12/145:00 pm -
1 stop6h 59m
Deal found 9/15![United Airlines logo]()
$334
This Breeze Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 am -
Nonstop1h 37m
Mon 11/910:17 am -
Nonstop1h 52m
Deal found 9/12![Breeze Airways logo]()
$193
This Breeze Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:42 am -
Nonstop1h 37m
Sat 10/249:53 am -
Nonstop1h 52m
Deal found 9/12![Breeze Airways logo]()
$208
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:55 am -
2 stops9h 55m
Sat 11/146:40 am -
1 stop6h 10m
Deal found 9/15![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:25 am -
Nonstop2h 09m
Sat 11/71:03 pm -
Nonstop2h 15m
Deal found 9/13![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 pm -
1 stop3h 30m
Wed 10/72:10 pm -
2 stops8h 55m
Deal found 9/14![Southwest logo]()
$284
This Breeze Airways deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:42 am -
Nonstop1h 37m
Wed 10/79:53 am -
Nonstop1h 52m
Deal found 9/13![Breeze Airways logo]()
$243
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
2 stops10h 25m
Mon 11/27:55 pm -
1 stop4h 00m
Deal found 9/16![Southwest logo]()
$289
This Breeze Airways deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:42 am -
Nonstop1h 37m
Wed 9/309:48 am -
Nonstop1h 52m
Deal found 9/12![Breeze Airways logo]()
$243
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:33 pm -
1 stop6h 24m
Mon 10/128:09 pm -
1 stop4h 48m
Deal found 9/15![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:05 am -
2 stops8h 20m
Thu 11/196:40 am -
1 stop6h 00m
Deal found 9/16![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:09 pm -
1 stop4h 10m
Mon 12/148:15 pm -
1 stop4h 53m
Deal found 9/16![Delta logo]()
$325
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:45 am -
1 stop6h 27m
Tue 10/203:04 pm -
1 stop7h 23m
Deal found 9/16![JetBlue logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:45 am -
2 stops11h 26m
Sun 11/2211:27 am -
2 stops12h 32m
Deal found 9/12![United Airlines logo]()
$399
This Breeze Airways deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1012:25 pm -
Nonstop1h 37m
Sat 10/179:53 am -
Nonstop1h 52m
Deal found 9/14![Breeze Airways logo]()
$248
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:45 am -
1 stop6h 27m
Sat 10/3110:50 am -
1 stop5h 59m
Deal found 9/12![JetBlue logo]()
$397
This Breeze Airways deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:42 am -
Nonstop1h 37m
Sat 10/179:53 am -
Nonstop1h 52m
Deal found 9/13![Breeze Airways logo]()
$248
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 am -
1 stop4h 10m
Wed 10/286:40 am -
1 stop6h 25m
Deal found 9/15![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:00 am -
1 stop5h 45m
Tue 12/155:00 pm -
1 stop6h 59m
Deal found 9/15![United Airlines logo]()
$409
This Breeze Airways deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 am -
Nonstop1h 37m
Mon 11/1610:17 am -
Nonstop1h 52m
Deal found 9/13![Breeze Airways logo]()
$248
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:40 pm -
2 stops10h 10m
Tue 11/37:40 am -
2 stops10h 45m
Deal found 9/14![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:51 am -
1 stop7h 50m
Sun 12/610:00 am -
1 stop7h 22m
Deal found 9/15![United Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:49 pm -
Nonstop2h 16m
Sat 10/317:10 am -
Nonstop2h 08m
Deal found 9/12![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 pm -
1 stop3h 35m
Wed 10/216:40 am -
2 stops8h 40m
Deal found 9/17![Southwest logo]()
$312
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/223:50 pm -
Nonstop2h 12m
Tue 12/296:47 pm -
Nonstop2h 13m
Deal found 9/15![Delta logo]()
$389
Last-minute flights from Ohio to South CarolinaDiscover last-minute flight deals from Ohio to South Carolina. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Ohio to South Carolina. Data last updated September 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:07 pm -
Nonstop2h 00m
Sat 9/267:47 pm -
Nonstop2h 00m
Deal found 9/16![Breeze Airways logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:35 am -
Nonstop2h 00m
Thu 10/19:44 pm -
Nonstop2h 00m
Deal found 9/16![Breeze Airways logo]()
$127
This Breeze Airways deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/42:34 pm -
Nonstop2h 00m
Thu 10/89:44 pm -
Nonstop2h 00m
Deal found 9/15![Breeze Airways logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:25 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/181:25 pm -
Nonstop1h 37m
Thu 10/222:32 pm -
Nonstop1h 36m
Deal found 9/15![Allegiant Air logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:00 am -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/15![Multiple Airlines logo]()
$120
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:05 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/14![Allegiant Air logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/252:34 pm -
Nonstop2h 00m
Thu 11/59:44 pm -
Nonstop2h 00m
Deal found 9/16![Breeze Airways logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:25 pm -
Nonstop1h 37m
Thu 10/292:32 pm -
Nonstop1h 36m
Deal found 9/14![Multiple Airlines logo]()
$119
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:05 pm -
Nonstop1h 37m
Wed 12/210:08 am -
Nonstop1h 52m
Deal found 9/14![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:34 pm -
Nonstop2h 00m
Thu 11/59:44 pm -
Nonstop2h 00m
Deal found 9/13![Breeze Airways logo]()
$142
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:58 pm -
Nonstop1h 41m
Thu 11/510:56 am -
Nonstop1h 48m
Deal found 9/15![Allegiant Air logo]()
$145
One-way flights from Ohio to South CarolinaSearch for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Ohio to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:20 pm -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Allegiant Air logo]()
$29
This CheapOair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:00 am -
Nonstop1h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Allegiant Air logo]()
$45
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:10 pm -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$47
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:18 pm -
Nonstop1h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Allegiant Air logo]()
$55
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:34 pm -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Breeze Airways logo]()
$58
This Super.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:13 pm -
Nonstop1h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Allegiant Air logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:44 pm -
Nonstop1h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Breeze Airways logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:00 am -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Breeze Airways logo]()
$63
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:35 am -
Nonstop1h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:00 am -
Nonstop1h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Breeze Airways logo]()
$64
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:38 am -
Nonstop1h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Allegiant Air logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/157:44 pm -
Nonstop1h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Breeze Airways logo]()
$68
Find flight deals from Ohio to South Carolina
Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $87 (CheapOair) |
One-way from | $29 (CheapOair) |
Popular in | March |
Cheapest in | April |
Average price | $249 |
Good round-trip deal | $108 or less |
Good one-way deal | $44 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
AkronSavannah
CAK Akron/Canton - SAV Savannah/Hilton Head
CAKSAV
Akron/Canton
Sun 10/18
6:18 pm-7:59 pm
Nonstop1h 41m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$56
AkronMyrtle Beach
CAK Akron/Canton - MYR Myrtle Beach Intl
CAKMYR
Akron/Canton
Fri 12/11
8:00 am-9:37 am
Nonstop1h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$73
AkronSavannah
CAK Akron/Canton - SAV Savannah/Hilton Head
CAKSAV
Akron/Canton
Thu 9/24
7:42 pm-9:26 pm
Nonstop1h 44m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$80
AkronSavannah
CAK Akron/Canton - SAV Savannah/Hilton Head
CAKSAV
Akron/Canton
Thu 10/29
2:34 pm-4:34 pm
Nonstop2h 00m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$84
PittsburghMyrtle Beach
PIT Pittsburgh - MYR Myrtle Beach Intl
PITMYR
Pittsburgh
Fri 9/25
7:44 pm-9:22 pm
Nonstop1h 38m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$94
ClevelandCharlotte
CLE Cleveland Hopkins Intl - CLT Charlotte Douglas
CLECLT
Cleveland Hopkins Intl
Wed 10/28
9:59 pm-8:37 am
1 stop10h 38m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$109
AkronMyrtle Beach
CAK Akron/Canton - MYR Myrtle Beach Intl
CAKMYR
Akron/Canton
Wed 10/14
12:25 pm-2:02 pm
Nonstop1h 37m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$109
PittsburghMyrtle Beach
PIT Pittsburgh - MYR Myrtle Beach Intl
PITMYR
Pittsburgh
Tue 11/17
6:10 am-10:45 am
1 stop4h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
PittsburghMyrtle Beach
PIT Pittsburgh - MYR Myrtle Beach Intl
PITMYR
Pittsburgh
Wed 10/28
9:55 am-4:15 pm
1 stop6h 20m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
ClevelandCharlotte
CLE Cleveland Hopkins Intl - CLT Charlotte Douglas
CLECLT
Cleveland Hopkins Intl
Fri 11/6
9:59 pm-8:37 am
1 stop10h 38m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$119
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Ohio to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
CAK-MYR
CAK-SAV
PIT-MYR
CLE-CLT
CLE-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ohio to South Carolina
USOH-USSC
CAK-MYR
CAK-SAV
PIT-MYR
CLE-CLT
What is the cheapest month to book a flight from Ohio to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $179). Flying from Ohio to South Carolina in December is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from OH to SC?
Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2026.
Unlike at noon, when flights are generally more expensive, you can save up to 32% on flights from Ohio to South Carolina by exploring options for tickets in the evening.
How much does it cost to fly round-trip from Ohio to South Carolina?
Airfare is below average for this route at the moment.
Ohio to South Carolina flights typically cost between $352 and $529 in October.The cheapest round-trip price found within the last 5 days was $181 on Multiple Airlines (Oct 19-Oct 22).
How far ahead should I book a flight from Ohio to South Carolina?
The price you pay for your flight from Ohio to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Ohio to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on August 1, 2026.
Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Saturday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 17, 2026.
Read reviews from past customers who have flown Breeze Airways,Delta, andAllegiant Air from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.4
Comfort
8.2
Entertainment
6.8
Crew
8.8
Food
6.8
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Ohio to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Ohio to South Carolina by cabin class
Find flights from Ohio to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ohio and South Carolina flights
Browse other Ohio and South Carolina flight options. Last updated on September 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Ohio after your stay in South Carolina
Ohio to South Carolina flights
Consider these flights traveling from Ohio to South Carolina.
Top 8 airlines flying from Ohio to South Carolina
Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$58 | Average$179 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$73 | Average$157 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$81 | Average$173 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$88 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$130 | Average$379 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$186 | Average$381 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$210 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$218 | Average$334 | FlexibilityNo cancel fee | On-time62% |