$555+ Cheap flights from Pittsburgh to Florence, SC (PIT - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — FLO
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to Florence
Cheapest
Best
Last-minute
Cheapest flights from Pittsburgh to FlorenceExplore the most affordable flight options available from Pittsburgh to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Pittsburgh to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:49 pm -
1 stop6h 07m
Mon 11/93:37 pm -
1 stop5h 13m
Deal found 10/23![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:21 pm -
2 stops17h 56m
Tue 12/156:24 am -
1 stop6h 13m
Deal found 10/25![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:21 pm -
2 stops17h 56m
Sun 12/132:42 pm -
1 stop4h 28m
Deal found 10/25![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:40 am -
1 stop4h 29m
Fri 11/132:35 pm -
1 stop4h 55m
Deal found 10/25![American Airlines logo]()
$931
Best flights from Pittsburgh to FlorenceDiscover carefully curated flight deals from Pittsburgh to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Pittsburgh to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:49 pm -
1 stop6h 07m
Mon 11/93:37 pm -
1 stop5h 13m
Deal found 10/23![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:21 pm -
2 stops17h 56m
Tue 12/156:24 am -
1 stop6h 13m
Deal found 10/25![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/105:47 am -
2 stops8h 30m
Sun 12/132:42 pm -
2 stops6h 35m
Deal found 10/25![American Airlines logo]()
$719
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:40 am -
1 stop4h 29m
Fri 11/132:35 pm -
1 stop4h 55m
Deal found 10/25![American Airlines logo]()
$931
Last-minute flights from Pittsburgh to FlorenceDiscover last-minute flight deals from Pittsburgh to Florence. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to Florence. Data last updated October 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:49 pm -
1 stop6h 07m
Mon 11/93:37 pm -
1 stop5h 13m
Deal found 10/23![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:40 am -
1 stop4h 29m
Fri 11/132:35 pm -
1 stop4h 55m
Deal found 10/25![American Airlines logo]()
$931
Find flight deals from Pittsburgh to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Pittsburgh (PIT) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $555 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Pittsburgh to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghFlorence
PIT Pittsburgh - FLO Florence
PITFLO
Pittsburgh
Fri 11/6
5:49 pm-11:56 pm
1 stop6h 07m
Florence
Mon 11/9
3:37 pm-8:50 pm
1 stop5h 13m
$555
PittsburghFlorence
PIT Pittsburgh - FLO Florence
PITFLO
Pittsburgh
Thu 12/10
8:21 pm-2:17 pm
2 stops17h 56m
Florence
Tue 12/15
6:24 am-12:37 pm
1 stop6h 13m
$562
PittsburghFlorence
PIT Pittsburgh - FLO Florence
PITFLO
Pittsburgh
Thu 12/10
5:47 am-2:17 pm
2 stops8h 30m
Florence
Sun 12/13
2:42 pm-9:17 pm
2 stops6h 35m
$719
Quickest round-trip
PittsburghFlorence
PIT Pittsburgh - FLO Florence
PITFLO
Pittsburgh
Mon 11/9
10:40 am-3:09 pm
1 stop4h 29m
Florence
Fri 11/13
2:35 pm-7:30 pm
1 stop4h 55m
$931
Sorted by cheapest first
Compare providers for flights from Pittsburgh to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Pittsburgh to Florence in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Pittsburgh-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Pittsburgh-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Pittsburgh-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Pittsburgh-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Pittsburgh-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Pittsburgh to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Pittsburgh with our price prediction graph.
PIT-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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