$50+ Cheap flights from Pittsburgh (PIT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — CHS
May 26 — Jun 21
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to South Carolina with Cheapflights
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Cheapest flights from Pittsburgh to South CarolinaExplore the most affordable flight options available from Pittsburgh to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
Explore the most affordable flight options available from Pittsburgh to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 26, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:52 pm
PIT
- SAV
Nonstop1h 43m
Allegiant Air
Sat 6/66:23 pm
SAV
- PIT
Nonstop1h 47m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$89
This Booking.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:32 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Tue 8/1811:11 am
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$115
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:07 pm
PIT
- MYR
Nonstop1h 31m
Allegiant Air
Mon 7/209:15 pm
MYR
- PIT
Nonstop1h 32m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$116
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:22 pm
PIT
- MYR
Nonstop1h 27m
Allegiant Air
Mon 6/89:36 pm
MYR
- PIT
Nonstop1h 35m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:22 pm
PIT
- MYR
Nonstop1h 27m
Allegiant Air
Fri 6/59:36 pm
MYR
- PIT
Nonstop1h 35m
Allegiant Air
Deal found 4/25![Allegiant Air logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Fri 11/63:06 pm
MYR
- PIT
Nonstop1h 30m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:47 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Fri 8/281:13 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:25 pm
PIT
- MYR
Nonstop1h 38m
Breeze Airways
Fri 9/185:09 pm
MYR
- PIT
Nonstop1h 36m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:32 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Wed 8/194:08 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:25 pm
PIT
- MYR
Nonstop1h 38m
Multiple Airlines
Fri 10/163:00 pm
MYR
- PIT
Nonstop1h 30m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:54 pm
PIT
- SAV
Nonstop1h 39m
Allegiant Air
Fri 10/211:56 am
SAV
- PIT
Nonstop1h 46m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Fri 10/163:00 pm
MYR
- PIT
Nonstop1h 30m
Allegiant Air
Deal found 4/21![Allegiant Air logo]()
$131
Best flights from Pittsburgh to South CarolinaDiscover carefully curated flight deals from Pittsburgh to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
Discover carefully curated flight deals from Pittsburgh to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 26, 2026.
This Breeze Airways deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:47 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Thu 6/183:23 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$233
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:40 am
PIT
- GSP
1 stop3h 27m
Delta
Tue 5/265:40 am
GSP
- PIT
1 stop3h 22m
Delta
Deal found 4/26![Delta logo]()
$253
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:10 am
PIT
- CHS
2 stops7h 55m
Southwest
Sat 6/65:30 am
CHS
- PIT
1 stop4h 45m
Southwest
Deal found 4/21![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1610:35 am
PIT
- SAV
1 stop4h 10m
United Airlines
Tue 5/198:08 am
SAV
- PIT
1 stop5h 03m
United Airlines
Deal found 4/23![United Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:55 am
PIT
- CAE
1 stop7h 00m
American Airlines
Sat 5/1610:49 am
CAE
- PIT
1 stop3h 51m
American Airlines
Deal found 4/24![American Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:54 pm
PIT
- GSP
1 stop22h 45m
Multiple Airlines
Sun 7/53:51 pm
GSP
- PIT
1 stop7h 48m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:55 pm
PIT
- AGS
1 stop4h 40m
Delta
Tue 6/168:24 pm
AGS
- PIT
1 stop4h 20m
Delta
Deal found 4/24![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:50 am
PIT
- GSP
2 stops9h 30m
Southwest
Tue 5/1912:50 pm
GSP
- PIT
2 stops9h 20m
Southwest
Deal found 4/22![Southwest logo]()
$282
This Breeze Airways deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/83:37 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Fri 6/121:13 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/22![Breeze Airways logo]()
$283
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:20 pm
PIT
- CHS
1 stop6h 25m
Delta
Thu 6/185:10 am
CHS
- PIT
1 stop3h 55m
Delta
Deal found 4/21![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:40 pm
PIT
- MYR
Nonstop1h 30m
Southwest
Thu 6/117:50 am
MYR
- PIT
1 stop3h 55m
Southwest
Deal found 4/21![Southwest logo]()
$292
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:46 pm
PIT
- CHS
1 stop5h 30m
Delta
Sat 6/209:00 am
CHS
- PIT
1 stop3h 52m
Delta
Deal found 4/23![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:04 pm
PIT
- CAE
1 stop4h 12m
American Airlines
Sun 5/246:39 pm
CAE
- PIT
1 stop5h 20m
American Airlines
Deal found 4/22![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:25 am
PIT
- CHS
1 stop4h 48m
Delta
Sat 7/118:05 am
CHS
- PIT
1 stop4h 47m
Delta
Deal found 4/21![Delta logo]()
$269
This Breeze Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:17 pm
PIT
- MYR
Nonstop1h 34m
Breeze Airways
Fri 7/1710:00 am
MYR
- PIT
Nonstop1h 37m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$328
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:00 am
PIT
- MYR
2 stops11h 40m
Southwest
Mon 6/88:10 pm
MYR
- PIT
1 stop3h 20m
Southwest
Deal found 4/21![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:10 am
PIT
- CAE
1 stop3h 37m
United Airlines
Sat 9/56:30 am
CAE
- PIT
1 stop6h 34m
United Airlines
Deal found 4/22![United Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:33 am
PIT
- CAE
1 stop3h 40m
American Airlines
Sat 5/910:36 am
CAE
- PIT
1 stop5h 37m
American Airlines
Deal found 4/23![American Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:13 am
PIT
- CHS
1 stop5h 40m
Delta
Wed 7/157:00 am
CHS
- PIT
1 stop5h 16m
Delta
Deal found 4/21![Delta logo]()
$269
This Breeze Airways deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:37 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Fri 6/261:13 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$333
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:45 pm
PIT
- MYR
2 stops9h 00m
Southwest
Sun 6/285:50 pm
MYR
- PIT
1 stop6h 00m
Southwest
Deal found 4/25![Southwest logo]()
$306
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:39 pm
PIT
- AGS
1 stop4h 19m
American Airlines
Mon 5/115:00 am
AGS
- PIT
1 stop4h 43m
American Airlines
Deal found 4/22![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:10 am
PIT
- MYR
1 stop5h 19m
Delta
Sun 6/147:54 pm
MYR
- PIT
1 stop5h 01m
Delta
Deal found 4/21![Delta logo]()
$273
This Breeze Airways deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:37 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Mon 5/251:13 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/21![Breeze Airways logo]()
$333
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:50 am
PIT
- GSP
2 stops9h 30m
Southwest
Mon 8/31:55 pm
GSP
- PIT
2 stops9h 10m
Southwest
Deal found 4/21![Southwest logo]()
$310
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:15 am
PIT
- HHH
1 stop6h 26m
United Airlines
Mon 5/113:08 pm
HHH
- PIT
1 stop5h 22m
United Airlines
Deal found 4/22![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:39 pm
PIT
- AGS
1 stop4h 19m
American Airlines
Sat 5/95:00 am
AGS
- PIT
2 stops8h 00m
American Airlines
Deal found 4/22![American Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:50 pm
PIT
- MYR
1 stop3h 50m
Southwest
Fri 6/127:50 am
MYR
- PIT
2 stops8h 10m
Southwest
Deal found 4/25![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 pm
PIT
- SAV
1 stop4h 59m
United Airlines
Mon 9/2811:26 am
SAV
- PIT
1 stop8h 08m
United Airlines
Deal found 4/21![United Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:20 pm
PIT
- GSP
1 stop5h 39m
Delta
Thu 6/181:09 pm
GSP
- PIT
1 stop5h 55m
Delta
Deal found 4/25![Delta logo]()
$293
Last-minute flights from Pittsburgh to South CarolinaDiscover last-minute flight deals from Pittsburgh to South Carolina. Data last updated April 26, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to South Carolina. Data last updated April 26, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:15 pm
PIT
- CLT
1 stop20h 28m
Frontier
Wed 5/137:58 pm
CLT
- PIT
1 stop22h 07m
Frontier
Deal found 4/23![Frontier logo]()
$153
This Super.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:06 am
PIT
- SAV
Nonstop1h 41m
Allegiant Air
Mon 5/117:30 am
SAV
- PIT
Nonstop1h 46m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:15 pm
PIT
- CLT
1 stop15h 50m
Multiple Airlines
Tue 5/123:16 pm
CLT
- PIT
1 stop26h 24m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:15 pm
PIT
- CLT
1 stop15h 50m
Multiple Airlines
Wed 5/135:35 pm
CLT
- PIT
1 stop28h 32m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:15 pm
PIT
- CLT
1 stop20h 28m
Multiple Airlines
Sat 5/236:00 am
CLT
- PIT
1 stop16h 07m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:15 pm
PIT
- CLT
1 stop15h 57m
Frontier
Thu 5/147:38 pm
CLT
- PIT
1 stop13h 11m
Frontier
Deal found 4/23![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:15 pm
PIT
- CLT
1 stop22h 58m
Frontier
Wed 5/137:58 pm
CLT
- PIT
1 stop22h 07m
Frontier
Deal found 4/24![Frontier logo]()
$162
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:02 pm
PIT
- CHS
Nonstop1h 44m
Breeze Airways
Thu 5/283:23 pm
CHS
- PIT
Nonstop1h 44m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
PIT
- MYR
1 stop14h 36m
Multiple Airlines
Mon 6/19:20 pm
MYR
- PIT
Nonstop1h 31m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
PIT
- MYR
1 stop14h 36m
Multiple Airlines
Sat 6/610:23 am
MYR
- PIT
Nonstop1h 35m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$154
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
PIT
- MYR
1 stop14h 36m
Multiple Airlines
Mon 6/19:20 pm
MYR
- PIT
Nonstop1h 31m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
PIT
- MYR
1 stop14h 36m
Multiple Airlines
Fri 6/59:36 pm
MYR
- PIT
Nonstop1h 35m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$155
One-way flights from Pittsburgh to South CarolinaSearch for one-way flight options from Pittsburgh to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
Search for one-way flight options from Pittsburgh to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$50
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$51
This Cheapflightsfares deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/101:33 pm
PIT
- MYR
Nonstop1h 33m
Allegiant Air
Deal found 4/22![Allegiant Air logo]()
$55
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:22 pm
PIT
- MYR
Nonstop1h 27m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$56
This Cheapflightsfares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:07 pm
PIT
- MYR
Nonstop1h 31m
Allegiant Air
Deal found 4/24![Allegiant Air logo]()
$60
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:00 am
PIT
- MYR
Nonstop1h 32m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$65
This Booking.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:44 pm
PIT
- GSP
Nonstop1h 27m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/291:19 pm
PIT
- MYR
Nonstop1h 33m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$68
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
PIT
- CLT
1 stop14h 02m
Spirit Airlines
Deal found 4/25![Spirit Airlines logo]()
$73
This Booking.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/178:15 pm
PIT
- CLT
1 stop15h 50m
Frontier
Deal found 4/24![Frontier logo]()
$76
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:15 pm
PIT
- SAV
Nonstop1h 44m
Allegiant Air
Deal found 4/23![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:15 pm
PIT
- CLT
1 stop15h 50m
Frontier
Deal found 4/21![Frontier logo]()
$79
Find flight deals from Pittsburgh to South Carolina
Keep the following information in mind while searching for Pittsburgh to South Carolina flight deals. Data was last updated April 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $89 (Cheapflightsfares) |
One-way from | $50 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $280 |
Good round-trip deal | $158 or less |
Good one-way deal | $64 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
Use the filters below to find and compare flights from Pittsburgh to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Thu 6/11
5:47 pm-7:31 pm
Nonstop1h 44m
Charleston
Thu 6/18
3:23 pm-5:07 pm
Nonstop1h 44m
$233
PittsburghGreenville
PIT - GSP
PITGSP
Pittsburgh
Sat 5/23
5:40 am-9:07 am
1 stop3h 27m
Greenville
Tue 5/26
5:40 am-9:02 am
1 stop3h 22m
$253
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Sat 5/30
6:10 am-2:05 pm
2 stops7h 55m
Charleston
Sat 6/6
5:30 am-10:15 am
1 stop4h 45m
$265
PittsburghAugusta
PIT - AGS
PITAGS
Pittsburgh
Tue 6/9
4:55 pm-9:35 pm
1 stop4h 40m
Augusta Bush Field
Tue 6/16
8:24 pm-12:44 am
1 stop4h 20m
$267
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Thu 6/11
6:20 pm-12:45 am
1 stop6h 25m
Charleston
Thu 6/18
5:10 am-9:05 am
1 stop3h 55m
$269
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Sat 6/13
5:46 pm-11:16 pm
1 stop5h 30m
Charleston
Sat 6/20
9:00 am-12:52 pm
1 stop3h 52m
$269
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Thu 7/9
5:25 am-10:13 am
1 stop4h 48m
Charleston
Sat 7/11
8:05 am-12:52 pm
1 stop4h 47m
$269
PittsburghCharleston
PIT - CHS
PITCHS
Pittsburgh
Thu 7/9
10:13 am-3:53 pm
1 stop5h 40m
Charleston
Wed 7/15
7:00 am-12:16 pm
1 stop5h 16m
$269
PittsburghMyrtle Beach
PIT - MYR
PITMYR
Pittsburgh
Wed 6/10
10:10 am-3:29 pm
1 stop5h 19m
Myrtle Beach Intl
Sun 6/14
7:54 pm-12:55 am
1 stop5h 01m
$273
PittsburghGreenville
PIT - GSP
PITGSP
Pittsburgh
Tue 5/12
6:50 am-4:20 pm
2 stops9h 30m
Greenville
Tue 5/19
12:50 pm-10:10 pm
2 stops9h 20m
$282
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Pittsburgh with our price prediction graph.
PIT-CHS
PIT-GSP
PIT-SAV
PIT-CAE
PIT-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to South Carolina
PIT-USSC
PIT-CHS
PIT-GSP
PIT-SAV
PIT-CAE
How far ahead should I book a flight from Pittsburgh to South Carolina?
Booking 50 days in advance of your planned departure date is, on average, the best time to get cheap flights from Pittsburgh to South Carolina. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Pittsburgh to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Pittsburgh to South Carolina (average of $47). Flying from Pittsburgh to South Carolina in August is currently the most expensive (average of $676). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to SC?
Find hourly flight availability from Pittsburgh to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 26, 2026.
A simple way to save on the total cost of your ticket is to fly from Pittsburgh to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 14% on your trip compared to booking a flight in the morning.
What is the cheapest day to fly from Pittsburgh to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Pittsburgh to South Carolina. Price data was last updated on August 17, 2025.
Travelers seeking maximum savings on their Pittsburgh to South Carolina flight should consider departing on Thursday mornings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from Pittsburgh to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 26, 2026.
See what other customers who have flown with Breeze Airways,Southwest, andAllegiant Air from Pittsburgh to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Entertainment
6.6
Overall
8.1
Comfort
8.2
Food
6.6
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to South Carolina by cabin class
Find flights from Pittsburgh to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and South Carolina flights
Browse other Pittsburgh and South Carolina flight options. Last updated on April 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Pittsburgh to South Carolina flights
Consider these flights traveling from Pittsburgh to South Carolina.
Top 7 airlines flying from Pittsburgh to South Carolina
Discover the top 7 airlines that operate flights from Pittsburgh to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$49 | Average$171 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$83 | Average$133 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$84 | Average$154 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$140 | Average$295 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$176 | Average$352 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$176 | Average$341 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$198 | Average$313 | FlexibilityNo cancel fee | On-time69% |