$69+ Cheap flights from South Carolina to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Apr 23 — Apr 301
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indiana with Cheapflights
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Cheapest flights from South Carolina to IndianaExplore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 24, 2026.
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
- ORD
1 stop13h 21m
Frontier
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/23![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/22![Frontier logo]()
$116
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:09 pm
CLT
- ORD
Nonstop2h 30m
Frontier
Sun 4/2612:38 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/20![Frontier logo]()
$117
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:43 pm
CLT
- ORD
Nonstop2h 21m
Frontier
Sun 4/2612:38 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/20![Frontier logo]()
$118
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Frontier
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/23![Frontier logo]()
$119
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:23 pm
CLT
- ORD
1 stop10h 36m
Frontier
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Deal found 3/22![Frontier logo]()
$120
This Trip.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1910:31 pm
CLT
- ORD
1 stop27h 38m
Frontier
Sun 4/2612:38 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/20![Frontier logo]()
$121
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:24 pm
CLT
- ORD
Nonstop2h 20m
Frontier
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Deal found 3/23![Frontier logo]()
$123
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:26 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 3/23![Frontier logo]()
$124
This CheapOair deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:49 pm
CLT
- ORD
1 stop15h 01m
Frontier
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Deal found 3/20![Frontier logo]()
$125
This Super.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:26 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Deal found 3/24![Frontier logo]()
$126
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:50 am
CLT
- IND
1 stop26h 59m
Frontier
Tue 5/51:46 pm
IND
- CLT
1 stop26h 57m
Frontier
Deal found 3/24![Frontier logo]()
$140
Best flights from South Carolina to IndianaDiscover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
Discover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 24, 2026.
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:05 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Wed 4/226:55 am
ORD
- CLT
Nonstop2h 11m
United Airlines
Deal found 3/23![United Airlines logo]()
$167
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Tue 4/286:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 3/22![Southwest logo]()
$168
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:45 am
GSP
- ORD
1 stop3h 49m
Delta
Wed 9/29:30 am
ORD
- GSP
1 stop5h 43m
Delta
Deal found 3/22![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:40 am
CLT
- ORD
1 stop7h 10m
Southwest
Tue 4/282:40 pm
ORD
- CLT
1 stop6h 00m
Southwest
Deal found 3/23![Southwest logo]()
$188
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:41 pm
SAV
- ORD
Nonstop2h 34m
American Airlines
Mon 9/218:05 am
ORD
- SAV
Nonstop2h 12m
American Airlines
Deal found 3/19![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Wed 4/226:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 3/23![Southwest logo]()
$202
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:05 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Sun 5/107:07 am
ORD
- CLT
Nonstop2h 23m
United Airlines
Deal found 3/19![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Thu 4/235:55 pm
MDW
- CLT
1 stop3h 45m
Southwest
Deal found 3/23![Southwest logo]()
$212
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:30 am
CLT
- MDW
1 stop5h 26m
Delta
Tue 4/219:27 am
MDW
- CLT
1 stop5h 33m
Delta
Deal found 3/22![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:31 am
SAV
- ORD
Nonstop2h 41m
United Airlines
Sat 4/183:55 pm
ORD
- SAV
Nonstop2h 20m
United Airlines
Deal found 3/19![United Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
GSP
- ORD
1 stop5h 45m
Southwest
Sat 5/91:55 pm
ORD
- GSP
1 stop5h 45m
Southwest
Deal found 3/22![Southwest logo]()
$219
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Sun 6/79:25 pm
ORD
- CLT
Nonstop2h 20m
United Airlines
Deal found 3/23![United Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:59 pm
GSP
- ORD
1 stop5h 00m
Delta
Sun 4/265:15 am
ORD
- GSP
1 stop4h 05m
Delta
Deal found 3/22![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Mon 5/47:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 3/21![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:06 pm
GSP
- ORD
1 stop4h 39m
Delta
Sun 7/128:03 am
ORD
- GSP
1 stop4h 58m
Delta
Deal found 3/22![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:35 pm
GSP
- ORD
1 stop5h 09m
United Airlines
Sat 5/97:50 pm
ORD
- GSP
Nonstop2h 08m
United Airlines
Deal found 3/22![United Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:05 pm
GSP
- ORD
1 stop5h 11m
Delta
Mon 6/226:00 am
ORD
- GSP
1 stop6h 08m
Delta
Deal found 3/20![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:30 pm
CLT
- MDW
1 stop4h 00m
Southwest
Wed 4/2212:50 pm
MDW
- CLT
2 stops6h 55m
Southwest
Deal found 3/23![Southwest logo]()
$244
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:35 pm
CAE
- ORD
Nonstop2h 30m
United Airlines
Wed 4/226:45 am
ORD
- CAE
Nonstop2h 06m
United Airlines
Deal found 3/20![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:42 pm
GSP
- ORD
1 stop5h 35m
Delta
Sun 8/308:15 am
ORD
- GSP
1 stop5h 37m
Delta
Deal found 3/20![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:30 am
MYR
- ORD
Nonstop2h 39m
United Airlines
Mon 5/1811:00 am
ORD
- MYR
Nonstop2h 18m
United Airlines
Deal found 3/20![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:00 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Sun 4/197:30 pm
MDW
- CLT
Nonstop2h 00m
Southwest
Deal found 3/20![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:10 am
GSP
- ORD
1 stop4h 27m
Delta
Mon 7/138:03 am
ORD
- GSP
1 stop4h 58m
Delta
Deal found 3/23![Delta logo]()
$289
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:29 pm
CLT
- IND
Nonstop1h 40m
American Airlines
Sun 4/198:16 am
IND
- CLT
Nonstop1h 49m
American Airlines
Deal found 3/19![American Airlines logo]()
$467
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:50 pm
GSP
- ORD
1 stop4h 54m
United Airlines
Mon 4/278:50 am
ORD
- GSP
Nonstop2h 04m
United Airlines
Deal found 3/21![United Airlines logo]()
$272
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:15 am
CLT
- MDW
1 stop6h 55m
Southwest
Sun 4/191:15 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 3/19![Southwest logo]()
$267
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:27 pm
CLT
- IND
Nonstop1h 41m
American Airlines
Mon 5/185:34 pm
IND
- CLT
Nonstop1h 48m
American Airlines
Deal found 3/19![American Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:50 am
CAE
- ORD
1 stop4h 37m
United Airlines
Tue 4/286:45 am
ORD
- CAE
Nonstop2h 06m
United Airlines
Deal found 3/23![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:30 pm
CLT
- ORD
1 stop5h 23m
Delta
Sun 6/147:01 am
ORD
- CLT
1 stop4h 25m
Delta
Deal found 3/22![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:45 am
GSP
- ORD
1 stop7h 05m
Southwest
Wed 4/292:40 pm
ORD
- GSP
1 stop6h 00m
Southwest
Deal found 3/21![Southwest logo]()
$275
Last-minute flights from South Carolina to IndianaDiscover last-minute flight deals from South Carolina to Indiana. Data last updated March 24, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indiana. Data last updated March 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:15 am
CLT
- MDW
1 stop8h 46m
Multiple Airlines
Tue 4/147:30 am
MDW
- CLT
1 stop5h 22m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$171
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:30 pm
CLT
- CVG
1 stop5h 50m
Frontier
Fri 4/178:17 pm
CVG
- CLT
1 stop20h 39m
Frontier
Deal found 3/24![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
- CVG
1 stop12h 58m
Frontier
Mon 4/205:20 pm
CVG
- CLT
1 stop23h 15m
Frontier
Deal found 3/23![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:56 am
CLT
- CVG
1 stop12h 58m
Frontier
Tue 4/215:20 pm
CVG
- CLT
1 stop23h 15m
Frontier
Deal found 3/23![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:32 pm
CLT
- CVG
1 stop12h 11m
Multiple Airlines
Mon 4/275:20 pm
CVG
- CLT
1 stop16h 57m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$166
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:35 am
CLT
- MDW
Nonstop2h 10m
Southwest
Tue 4/286:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 3/24![Southwest logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:32 pm
CLT
- CVG
1 stop21h 32m
Multiple Airlines
Mon 4/276:00 am
CVG
- CLT
1 stop14h 37m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
- CVG
1 stop12h 43m
Multiple Airlines
Mon 4/275:20 pm
CVG
- CLT
1 stop16h 57m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:30 am
CLT
- CVG
1 stop7h 56m
Multiple Airlines
Mon 4/2710:00 am
CVG
- CLT
1 stop10h 37m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$159
This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:09 pm
CLT
- IND
1 stop15h 02m
Frontier
Mon 5/411:29 am
IND
- CLT
1 stop24h 36m
Frontier
Deal found 3/24![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:09 pm
CLT
- IND
1 stop11h 34m
Frontier
Fri 5/18:23 am
IND
- CLT
1 stop8h 07m
Frontier
Deal found 3/24![Frontier logo]()
$160
This Expedia deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:09 pm
CLT
- MDW
1 stop12h 12m
Frontier
Thu 4/308:25 am
MDW
- CLT
1 stop6h 32m
Frontier
Deal found 3/21![Frontier logo]()
$160
One-way flights from South Carolina to IndianaSearch for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
Search for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated March 24, 2026.
This Super.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/274:47 pm
CLT
- ORD
1 stop9h 05m
Frontier
Deal found 3/21![Frontier logo]()
$69
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:43 pm
CLT
- ORD
Nonstop2h 21m
Frontier
Deal found 3/20![Frontier logo]()
$73
This Super.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:09 pm
CLT
- ORD
Nonstop2h 30m
Frontier
Deal found 3/23![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1910:31 pm
CLT
- ORD
1 stop27h 38m
Frontier
Deal found 3/20![Frontier logo]()
$75
This Frontier deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:09 pm
CLT
- IND
1 stop11h 29m
Frontier
Deal found 3/23![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:09 pm
CLT
- MDW
1 stop12h 50m
Frontier
Deal found 3/20![Frontier logo]()
$76
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:56 am
CLT
- ORD
1 stop13h 21m
Frontier
Deal found 3/22![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:31 pm
CLT
- CVG
1 stop10h 51m
Frontier
Deal found 3/23![Frontier logo]()
$76
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/38:50 am
CLT
- IND
1 stop26h 59m
Frontier
Deal found 3/20![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:17 am
CLT
- CVG
1 stop12h 03m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:04 pm
CHS
- MDW
1 stop25h 56m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:18 am
CLT
- MDW
1 stop28h 42m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$79
Find flight deals from South Carolina to Indiana
Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated March 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $114 (Expedia) |
One-way from | $69 (Super.com) |
Popular in | March |
Cheapest in | August |
Average price | $486 |
Good round-trip deal | $83 or less |
Good one-way deal | $119 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteChicago
CLT - ORD
CLTORD
Charlotte Douglas
Tue 4/21
8:05 am-9:23 am
Nonstop2h 18m
Chicago O'Hare Intl
Wed 4/22
6:55 am-10:06 am
Nonstop2h 11m
$167
CharlotteChicago
CLT - MDW
CLTMDW
Charlotte Douglas
Tue 4/21
6:20 pm-7:25 pm
Nonstop2h 05m
Chicago Midway
Tue 4/28
6:00 pm-8:55 pm
Nonstop1h 55m
$168
CharlotteChicago
CLT - ORD
CLTORD
Charlotte Douglas
Tue 4/21
6:40 am-12:50 pm
1 stop7h 10m
Chicago O'Hare Intl
Tue 4/28
2:40 pm-9:40 pm
1 stop6h 00m
$188
CharlotteChicago
CLT - MDW
CLTMDW
Charlotte Douglas
Tue 4/21
6:20 pm-7:25 pm
Nonstop2h 05m
Chicago Midway
Wed 4/22
6:00 pm-8:55 pm
Nonstop1h 55m
$202
CharlotteChicago
CLT - MDW
CLTMDW
Charlotte Douglas
Tue 4/21
6:20 pm-7:25 pm
Nonstop2h 05m
Chicago Midway
Thu 4/23
5:55 pm-10:40 pm
1 stop3h 45m
$212
GreenvilleChicago
GSP - ORD
GSPORD
Greenville
Sat 5/2
10:45 am-3:30 pm
1 stop5h 45m
Chicago O'Hare Intl
Sat 5/9
1:55 pm-8:40 pm
1 stop5h 45m
$219
CharlotteChicago
CLT - ORD
CLTORD
Charlotte Douglas
Fri 5/8
8:05 am-9:23 am
Nonstop2h 18m
Chicago O'Hare Intl
Sun 5/10
7:07 am-10:30 am
Nonstop2h 23m
$237
CharlotteChicago
CLT - MDW
CLTMDW
Charlotte Douglas
Fri 5/1
7:00 pm-8:05 pm
Nonstop2h 05m
Chicago Midway
Mon 5/4
7:05 pm-10:00 pm
Nonstop1h 55m
$237
CharlotteChicago
CLT - MDW
CLTMDW
Charlotte Douglas
Mon 4/20
8:30 pm-11:30 pm
1 stop4h 00m
Chicago Midway
Wed 4/22
12:50 pm-8:45 pm
2 stops6h 55m
$244
SavannahChicago
SAV - ORD
SAVORD
Savannah/Hilton Head
Wed 4/15
11:31 am-1:12 pm
Nonstop2h 41m
Chicago O'Hare Intl
Sat 4/18
3:55 pm-7:15 pm
Nonstop2h 20m
$254
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
CLT-CVG
CLT-IND
CLT-MDW
CLT-ORD
CHS-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indiana
USSC-USIN
CLT-CVG
CLT-IND
CLT-MDW
CLT-ORD
What is the cheapest month to book a flight from South Carolina to Indiana?
Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in April is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IN?
Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 24, 2026.
One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 72% on airfare.
What is the cheapest day to fly from South Carolina to Indiana?
Use this chart to determine the cheapest time to fly round-trip from South Carolina to Indiana. Price data was last updated on March 23, 2026.
Travelers seeking maximum savings on their South Carolina to Indiana flight should consider departing on Tuesday at noon when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated March 24, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Delta,United Airlines, andAllegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indiana by cabin class
Find flights from South Carolina to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Indiana flights
Browse other South Carolina and Indiana flight options. Last updated on March 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to South Carolina after your stay in Indiana
South Carolina to Indiana flights
Consider these flights traveling from South Carolina to Indiana.
Top 5 airlines flying from South Carolina to Indiana
Discover the top 5 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$45 | Average$123 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$83 | Average$201 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$125 | Average$335 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$190 | Average$348 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$375 | FlexibilityNo cancel fee | On-time71% |