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Indiana

$64+ Cheap flights from South Carolina to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from South Carolina to Indiana

Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated September 16, 2025.

Round-trip from

$114
(Priceline)

One-way from

$64
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$308

Good one-way deal

$119 or less
From South Carolina to Indiana
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One-way flight from South Carolina to Indiana
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Highest demand for flights based on searches. 34% potential increase in price ($192 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a one-way flight from South Carolina to Indiana.
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Find flight deals from South Carolina to Indiana

Cheapest flights from South Carolina to Indiana
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:51 pmCLT - ORD
Nonstop2h 22mFrontier
Sun 11/25:00 amORD - CLT
1 stop10h 17mFrontier
Deal found 9/15$114
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:42 amCLT - ORD
1 stop9h 33mFrontier
Sun 10/266:00 amORD - CLT
Nonstop2h 08mFrontier
Deal found 9/15$115
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/168:48 amCLT - ORD
1 stop9h 52mFrontier
Sun 10/196:00 amORD - CLT
Nonstop2h 08mFrontier
Deal found 9/15$116
This Flightnetwork deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:07 pmCLT - ORD
1 stop7h 09mFrontier
Fri 11/711:53 amORD - CLT
Nonstop2h 05mFrontier
Deal found 9/16$117
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:50 pmCLT - ORD
Nonstop2h 22mFrontier
Sun 11/96:00 amORD - CLT
1 stop10h 35mFrontier
Deal found 9/16$118
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:38 pmCLT - ORD
1 stop7h 21mFrontier
Sun 10/57:40 amORD - CLT
Nonstop2h 20mFrontier
Deal found 9/15$121
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:50 amCLT - ORD
Nonstop2h 22mFrontier
Sun 10/57:40 amORD - CLT
Nonstop2h 20mFrontier
Deal found 9/15$122
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:40 pmCLT - ORD
1 stop7h 53mMultiple Airlines
Sun 10/196:00 amORD - CLT
Nonstop2h 08mMultiple Airlines
Deal found 9/14$124
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmCLT - ORD
1 stop7h 39mFrontier
Mon 10/67:40 amORD - CLT
Nonstop2h 20mFrontier
Deal found 9/14$125
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amCLT - ORD
1 stop5h 13mMultiple Airlines
Sat 11/111:51 amORD - CLT
Nonstop2h 05mMultiple Airlines
Deal found 9/14$126
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:30 amCLT - MDW
Nonstop1h 55mSouthwest
Wed 11/56:00 pmMDW - CLT
Nonstop1h 50mSouthwest
Deal found 9/16$139
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:50 pmCLT - MDW
1 stop9h 21mFrontier
Fri 10/31:49 pmMDW - CLT
1 stop6h 36mFrontier
Deal found 9/15$143

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

Fly from

South Carolina

Fly to

Indiana

Route

Depart

Return

Price

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 10/30

6:07 pm-12:43 am

1 stop7h 36m

Chicago O'Hare Intl

Mon 11/3

11:53 am-2:58 pm

Nonstop2h 05m

$115

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Fri 10/10

5:34 pm-1:49 am

1 stop8h 15m

Cincinnati Cinci./N. Kentucky

Mon 10/13

12:01 pm-6:34 pm

1 stop6h 33m

$143

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Fri 9/26

12:17 pm-10:02 pm

1 stop9h 45m

Cincinnati Cinci./N. Kentucky

Sun 9/28

6:05 am-3:03 pm

1 stop8h 58m

$143

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Thu 10/2

1:11 pm-11:59 pm

1 stop10h 48m

Cincinnati Cinci./N. Kentucky

Sun 10/5

6:05 am-3:03 pm

1 stop8h 58m

$143

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 10/14

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

Tue 10/21

11:20 am-2:42 pm

Nonstop2h 22m

$147

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 10/17

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

Tue 10/21

11:20 am-2:42 pm

Nonstop2h 22m

$147

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 10/14

10:25 am-11:36 am

Nonstop2h 11m

Chicago O'Hare Intl

Tue 10/21

1:55 pm-5:05 pm

Nonstop2h 10m

$149

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 10/25

6:30 am-7:25 am

Nonstop1h 55m

Chicago Midway

Sun 10/26

8:25 pm-11:15 pm

Nonstop1h 50m

$151

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 10/24

7:26 pm-11:50 pm

1 stop5h 24m

Chicago O'Hare Intl

Mon 10/27

6:36 pm-11:59 pm

1 stop4h 23m

$151

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 11/1

6:30 am-7:25 am

Nonstop1h 55m

Chicago Midway

Mon 11/3

1:30 pm-4:20 pm

Nonstop1h 50m

$151

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indiana

What is the cheapest month to book a flight from South Carolina to Indiana?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $286). Flying from South Carolina to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IN?

Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indiana as you normally would.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,924 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,019 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Indiana flight route?

    The South Carolina to Indiana flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Indiana?

    Frontier, United Airlines, and Southwest can get you from South Carolina to Indiana in just under 1h 55m. Your travel time can differ by up to 5h 41m. The distance from South Carolina to Indiana is about 583 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Indiana one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $66. Users have also found prices from $70 and $72 on Southwest and Frontier, respectively.

  • Can I find deals for flights from South Carolina to Indiana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indiana.

  • Can I find deals for business class flights from South Carolina to Indiana?

    Yes. Cheapflights offers flight deals from South Carolina to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indiana?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $286). Flying from South Carolina to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indiana

Discover the top 6 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$45Average$133FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$149Average$251FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$189Average$374FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$190Average$405FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$369FlexibilityNo cancel feeOn-timeN/A

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