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$54+ Cheap flights from South Carolina to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from South Carolina to Indiana

Cheapest flights from South Carolina to Indiana
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:27 amCLT - ORD
Nonstop2h 13mFrontier
Thu 1/15:25 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/16$78
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:27 amCLT - ORD
Nonstop2h 13mFrontier
Tue 12/306:50 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/16$113
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:39 pmCLT - ORD
1 stop6h 27mFrontier
Fri 1/25:45 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/16$121
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:52 amCLT - ORD
Nonstop2h 13mFrontier
Sun 1/45:05 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/16$125
This Super.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:47 amCLT - ORD
Nonstop2h 13mFrontier
Sun 1/45:05 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/15$128
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:27 amCLT - ORD
Nonstop2h 13mMultiple Airlines
Wed 1/145:57 pmORD - CLT
2 stops37h 21mMultiple Airlines
Deal found 12/16$136
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:09 pmCLT - ORD
Nonstop2h 31mUnited Airlines
Thu 12/256:05 pmORD - CLT
Nonstop2h 15mUnited Airlines
Deal found 12/16$139
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:09 pmCLT - ORD
Nonstop2h 31mUnited Airlines
Wed 1/142:18 pmORD - CLT
Nonstop2h 06mUnited Airlines
Deal found 12/16$149
This Super.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:39 pmCLT - ORD
1 stop6h 27mFrontier
Thu 12/255:25 amORD - CLT
Nonstop2h 07mFrontier
Deal found 12/16$155
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:14 pmCLT - ORD
1 stop27h 52mMultiple Airlines
Thu 1/15:25 amORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 12/17$160
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:17 pmCLT - CVG
1 stop13h 51mFrontier
Sat 1/109:00 amCVG - CLT
1 stop7h 42mFrontier
Deal found 12/16$187
This Southwest deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:20 pmCLT - MDW
Nonstop2h 05mSouthwest
Wed 12/316:00 pmMDW - CLT
Nonstop1h 50mSouthwest
Deal found 12/17$209

Find flight deals from South Carolina to Indiana

Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$77
(Super.com)

One-way from

$54
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$326

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indiana
Search Deals
One-way flight from South Carolina to Indiana
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($162 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a one-way flight from South Carolina to Indiana.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

Fly from

South Carolina

Fly to

Indiana

Route

Depart

Return

Price

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Tue 1/13

5:38 pm-6:50 pm

1 stop25h 12m

Cincinnati Cinci./N. Kentucky

Tue 1/20

4:23 pm-10:40 am

1 stop18h 17m

$133

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sun 1/18

10:44 am-12:12 pm

Nonstop2h 28m

Chicago O'Hare Intl

Sun 1/18

6:15 pm-9:37 pm

Nonstop2h 22m

$139

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Tue 1/13

5:38 pm-6:50 pm

1 stop25h 12m

Cincinnati Cinci./N. Kentucky

Tue 1/20

9:00 am-12:40 am

2 stops15h 40m

$145

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 1/17

1:05 pm-5:20 pm

1 stop5h 15m

Chicago Midway

Sun 1/18

1:30 pm-4:20 pm

Nonstop1h 50m

$149

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Wed 1/14

6:10 am-7:43 am

Nonstop2h 33m

Chicago O'Hare Intl

Sat 1/17

6:15 pm-9:37 pm

Nonstop2h 22m

$149

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 1/22

11:12 am-7:36 pm

1 stop8h 24m

Indianapolis

Sun 1/25

9:34 pm-9:30 am

1 stop11h 56m

$154

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Mon 1/26

1:24 pm-10:48 pm

1 stop9h 24m

Indianapolis

Thu 1/29

10:38 am-4:54 pm

1 stop6h 16m

$157

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Thu 1/15

6:20 pm-7:25 pm

Nonstop2h 05m

Chicago Midway

Sun 1/18

1:30 pm-4:20 pm

Nonstop1h 50m

$158

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 1/27

10:44 am-12:12 pm

Nonstop2h 28m

Chicago O'Hare Intl

Sun 2/22

7:10 am-10:26 am

Nonstop2h 16m

$158

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Thu 1/15

6:00 am-2:57 pm

1 stop8h 57m

Cincinnati Cinci./N. Kentucky

Sun 1/18

6:55 am-5:58 pm

1 stop11h 03m

$160

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indiana

What is the cheapest month to book a flight from South Carolina to Indiana?

Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in April is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IN?

Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 14% on airfare.

What is the cheapest day to fly from South Carolina to Indiana?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Indiana. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Indiana flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Delta, United Airlines, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
700 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,191 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Indiana flight route?

    The South Carolina to Indiana flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Indiana?

    Frontier, United Airlines, and Southwest can get you from South Carolina to Indiana in just under 2h 28m. Your travel time can differ by up to 22h 44m. The distance from South Carolina to Indiana is about 599 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Indiana one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $38. Users have also found prices from $75 and $98 on Spirit Airlines and Delta, respectively.

  • Can I find deals for flights from South Carolina to Indiana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indiana.

  • Can I find deals for business class flights from South Carolina to Indiana?

    Yes. Cheapflights offers flight deals from South Carolina to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indiana?

    Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in April is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indiana

Discover the top 6 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$45Average$133FlexibilityNo cancel feeOn-time88%
DeltaCheapest$125Average$363FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$146Average$202FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$189Average$388FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$190Average$362FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$363FlexibilityNo cancel feeOn-time71%

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