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$62+ Cheap flights from South Carolina to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from South Carolina to Indiana

Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$157
(Cheapflightsfares)

One-way from

$62
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$287

Good round-trip deal

$81 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
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From South Carolina to Indiana
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One-way flight from South Carolina to Indiana
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Highest demand for flights based on searches. 34% potential increase in price ($194 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from South Carolina to Indiana.
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Find flight deals from South Carolina to Indiana

Cheapest flights from South Carolina to Indiana
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:34 pmCLT - IND
1 stop5h 25mSpirit Airlines
Sun 6/19:14 pmIND - CLT
Nonstop1h 45mSpirit Airlines
Deal found 4/30$157
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/99:40 amCLT - ORD
1 stop5h 26mMultiple Airlines
Thu 6/126:06 pmORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 4/30$157
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2512:07 pmSAV - ORD
Nonstop2h 38mAmerican Airlines
Mon 7/288:15 amORD - SAV
Nonstop2h 12mAmerican Airlines
Deal found 4/30$157
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/126:34 pmCLT - ORD
1 stop5h 55mSpirit Airlines
Sat 5/177:47 amORD - CLT
1 stop7h 04mSpirit Airlines
Deal found 4/30$162
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1710:19 pmCLT - ORD
Nonstop2h 25mFrontier
Tue 7/297:00 amORD - CLT
1 stop8h 36mFrontier
Deal found 4/30$168
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/121:18 pmCAE - ORD
1 stop6h 26mSpirit Airlines
Sun 6/155:15 amORD - CAE
1 stop6h 08mSpirit Airlines
Deal found 4/30$175
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:36 pmCLT - IND
1 stop11h 05mFrontier
Sun 5/189:18 amIND - CLT
1 stop7h 21mFrontier
Deal found 4/29$180
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/164:21 pmCLT - CVG
1 stop8h 38mFrontier
Sun 5/185:20 amCVG - CLT
1 stop11h 19mFrontier
Deal found 4/29$180
This Priceline deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:38 pmCLT - IND
Nonstop1h 41mMultiple Airlines
Sun 5/189:18 amIND - CLT
1 stop7h 21mMultiple Airlines
Deal found 4/29$182
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:35 amCLT - MDW
Nonstop1h 55mSouthwest
Tue 7/87:45 pmMDW - CLT
Nonstop1h 50mSouthwest
Deal found 4/30$185
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:22 pmCLT - ORD
Nonstop2h 13mAmerican Airlines
Sat 7/267:05 amORD - CLT
Nonstop2h 04mAmerican Airlines
Deal found 4/30$185
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/98:26 pmSAV - ORD
1 stop4h 32mDelta
Fri 6/205:59 pmORD - SAV
1 stop3h 48mDelta
Deal found 4/30$197

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

Fly from

South Carolina

Fly to

Indiana

Route

Depart

Return

Price

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Fri 5/30

6:34 pm-11:59 pm

1 stop5h 25m

Indianapolis

Sun 6/1

9:14 pm-10:59 pm

Nonstop1h 45m

$157

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Mon 6/9

9:40 am-2:06 pm

1 stop5h 26m

Chicago O'Hare Intl

Thu 6/12

6:06 pm-9:13 pm

Nonstop2h 07m

$157

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Fri 7/25

12:07 pm-1:45 pm

Nonstop2h 38m

Chicago O'Hare Intl

Mon 7/28

8:15 am-11:27 am

Nonstop2h 12m

$157

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Mon 5/12

6:34 pm-11:29 pm

1 stop5h 55m

Chicago O'Hare Intl

Sat 5/17

7:47 am-3:51 pm

1 stop7h 04m

$162

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Thu 7/17

10:19 pm-11:44 pm

Nonstop2h 25m

Chicago O'Hare Intl

Tue 7/29

7:00 am-4:36 pm

1 stop8h 36m

$168

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

Thu 6/12

1:18 pm-6:44 pm

1 stop6h 26m

Chicago O'Hare Intl

Sun 6/15

5:15 am-12:23 pm

1 stop6h 08m

$175

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

10:36 pm-9:41 am

1 stop11h 05m

Indianapolis

Sun 5/18

9:18 am-4:39 pm

1 stop7h 21m

$180

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Fri 5/16

4:21 pm-12:59 am

1 stop8h 38m

Cincinnati Cinci./N. Kentucky

Sun 5/18

5:20 am-4:39 pm

1 stop11h 19m

$180

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

6:38 pm-8:19 pm

Nonstop1h 41m

Indianapolis

Sun 5/18

9:18 am-4:39 pm

1 stop7h 21m

$182

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Fri 7/4

6:35 am-7:30 am

Nonstop1h 55m

Chicago Midway

Tue 7/8

7:45 pm-10:35 pm

Nonstop1h 50m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indiana

What is the cheapest month to book a flight from South Carolina to Indiana?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $297). Flying from South Carolina to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IN?

Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indiana as you normally would.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Alaska Airlines, Southwest and Delta from South Carolina to Indiana. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,972 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,294 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Avelo Airlines
7.5
Good
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Comfort

7.9

Boarding

8.1

Entertainment

7.1

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Indiana flight route?

    The South Carolina to Indiana flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indiana one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $62. Users have also found prices from $79 and $81 on American Airlines and Southwest, respectively.

  • Can I find deals for flights from South Carolina to Indiana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indiana.

  • Can I find deals for business class flights from South Carolina to Indiana?

    Yes. Cheapflights offers flight deals from South Carolina to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indiana?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $297). Flying from South Carolina to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indiana

Discover the top 6 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$67Average$136FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$115Average$235FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$198Average$390FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$388FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$337FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$286Average$402FlexibilityNo cancel feeOn-time63%

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