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$54+ Cheap flights from South Carolina to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Find flight deals from South Carolina to Indiana

Cheapest flights from South Carolina to Indiana
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Frontier deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/1310:51 pmCLT - ORD
1 stop9h 35mFrontier
sáb. 11/1511:51 amORD - CLT
Nonstop2h 05mFrontier
Deal found 10/29$94
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/49:17 amCLT - ORD
Nonstop2h 13mFrontier
dom. 12/79:47 amORD - CLT
1 stop7h 00mFrontier
Deal found 10/30$96
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/83:07 pmCLT - ORD
1 stop9h 50mFrontier
dom. 12/148:55 amORD - CLT
Nonstop2h 07mFrontier
Deal found 10/29$97
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/143:07 pmCLT - ORD
1 stop8h 34mFrontier
lun. 12/158:50 amORD - CLT
Nonstop2h 07mFrontier
Deal found 10/30$99
This Booking.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:33 pmCLT - ORD
1 stop15h 43mFrontier
dom. 12/148:55 amORD - CLT
Nonstop2h 07mFrontier
Deal found 10/30$100
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/134:31 pmSAV - CVG
Nonstop1h 40mAllegiant Air
lun. 11/177:00 amCVG - SAV
Nonstop1h 34mAllegiant Air
Deal found 10/30$105
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/52:58 pmCLT - ORD
1 stop6h 03mMultiple Airlines
dom. 12/78:55 amORD - CLT
Nonstop2h 07mMultiple Airlines
Deal found 10/29$107
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/136:00 amCLT - ORD
1 stop9h 31mMultiple Airlines
sáb. 11/158:00 amORD - CLT
1 stop7h 10mMultiple Airlines
Deal found 10/29$108
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/274:17 pmCLT - ORD
Nonstop2h 22mMultiple Airlines
mié. 12/310:59 amORD - CLT
1 stop6h 42mMultiple Airlines
Deal found 10/30$109
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/151:18 pmCLT - MDW
1 stop20h 54mFrontier
lun. 11/179:27 amMDW - CLT
1 stop27h 05mFrontier
Deal found 10/30$110
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/176:12 pmCLT - CVG
1 stop7h 27mFrontier
mar. 11/188:00 amCVG - CLT
1 stop5h 32mFrontier
Deal found 10/28$110
This Booking.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/149:24 amSAV - CVG
Nonstop1h 40mAllegiant Air
dom. 11/162:07 pmCVG - SAV
Nonstop1h 34mAllegiant Air
Deal found 10/29$111

Cheap flight deals from South Carolina to Indiana

Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$94
(Frontier)

One-way from

$54
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$333

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indiana
Search Deals
One-way flight from South Carolina to Indiana
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($187 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a one-way flight from South Carolina to Indiana.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

Fly from

South Carolina

Fly to

Indiana

Route

Depart

Return

Price

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

dom. 1/25

4:50 pm-6:41 pm

Nonstop1h 51m

Cincinnati Cinci./N. Kentucky

dom. 2/1

7:31 pm-9:08 pm

Nonstop1h 37m

$95

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

jue. 1/15

4:50 pm-6:41 pm

Nonstop1h 51m

Cincinnati Cinci./N. Kentucky

dom. 1/18

7:31 pm-9:08 pm

Nonstop1h 37m

$95

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

jue. 11/13

4:31 pm-6:11 pm

Nonstop1h 40m

Cincinnati Cinci./N. Kentucky

lun. 11/17

7:00 am-8:34 am

Nonstop1h 34m

$105

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

vie. 11/14

9:24 am-11:04 am

Nonstop1h 40m

Cincinnati Cinci./N. Kentucky

dom. 11/16

2:07 pm-3:41 pm

Nonstop1h 34m

$111

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

vie. 11/14

9:24 am-11:04 am

Nonstop1h 40m

Cincinnati Cinci./N. Kentucky

sáb. 1/3

9:31 pm-11:05 pm

Nonstop1h 34m

$119

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

jue. 11/13

6:07 pm-12:15 am

1 stop7h 08m

Chicago O'Hare Intl

dom. 11/16

11:43 am-2:48 pm

Nonstop2h 05m

$124

SavannahCincinnati

SAV - CVG

SAVCVG

Savannah/Hilton Head

vie. 1/23

7:00 am-1:17 pm

1 stop6h 17m

Cincinnati Cinci./N. Kentucky

dom. 1/25

7:31 pm-9:08 pm

Nonstop1h 37m

$137

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

vie. 11/7

3:53 pm-5:15 pm

Nonstop2h 22m

Chicago O'Hare Intl

sáb. 11/15

8:00 am-4:10 pm

1 stop7h 10m

$149

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

mié. 12/3

10:45 am-5:44 pm

1 stop6h 59m

Cincinnati Cinci./N. Kentucky

jue. 12/4

5:05 am-1:41 pm

1 stop8h 36m

$150

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

lun. 12/8

6:30 am-7:52 am

Nonstop2h 22m

Chicago O'Hare Intl

mar. 12/9

6:19 pm-9:39 pm

Nonstop2h 20m

$151

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indiana

What is the cheapest month to book a flight from South Carolina to Indiana?

Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in April is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IN?

Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 12% on airfare.

What is the cheapest day to fly from South Carolina to Indiana?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Indiana. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Indiana flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated octubre 30, 2025.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,116 reviews
Southwest
8.0
Very good
4,243 reviews

Comfort

8.0

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this South Carolina to Indiana flight route?

    The South Carolina to Indiana flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from South Carolina to Indiana?

    Allegiant Air, Frontier, and United Airlines can get you from South Carolina to Indiana in just under 1h 51m. Your travel time can differ by up to 5h 17m. The distance from South Carolina to Indiana is about 516 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Indiana one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $55. Users have also found prices from $62 and $70 on Allegiant Air and Spirit Airlines, respectively.

  • Can I find deals for flights from South Carolina to Indiana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indiana.

  • Can I find deals for business class flights from South Carolina to Indiana?

    Yes. Cheapflights offers flight deals from South Carolina to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indiana?

    Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in April is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indiana

Discover the top 6 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$45Average$133FlexibilityNo cancel feeOn-time88%
DeltaCheapest$125Average$366FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$146Average$257FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$189Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$190Average$395FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$371FlexibilityNo cancel feeOn-time71%

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