$49+ Cheap flights from Indiana to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
6월 3 — 6월 101
Round-trip
1 adult, Economy
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Cheapest flights from Indiana to South CarolinaExplore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5월 4, 2026.
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5월 4, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/3012:29 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
목 6/47:30 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$112
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2910:03 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
월 6/17:33 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/316:44 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
금 6/56:00 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$119
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2910:03 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
일 5/319:11 pm
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$123
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 8/79:47 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
월 8/101:12 pm
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$126
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 5/149:07 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 5/232:56 pm
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/3012:29 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
월 6/17:33 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$129
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 7/98:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
일 7/126:12 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$131
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 6/216:33 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 6/278:48 pm
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 6/276:23 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 7/49:09 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$135
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/179:07 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 5/2310:27 am
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$136
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 5/147:30 am
ORD
- CLT
1 stop9h 18m
Frontier
토 5/237:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/29![Frontier logo]()
$160
Best flights from Indiana to South CarolinaDiscover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 5월 4, 2026.
Discover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 5월 4, 2026.
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 6/176:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
수 6/245:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Deal found 5/1![United Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/307:00 am
ORD
- GSP
1 stop3h 55m
Delta
화 6/23:00 pm
GSP
- ORD
1 stop4h 41m
Delta
Deal found 4/30![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 6/48:10 am
MDW
- CHS
Nonstop2h 15m
Southwest
월 6/84:45 pm
CHS
- MDW
1 stop3h 50m
Southwest
Deal found 4/29![Southwest logo]()
$275
This Contour deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 5/2711:20 am
ORD
- CLT
1 stop4h 40m
Contour
수 6/36:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 4/29![Contour logo]()
$285
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/298:00 am
ORD
- CLT
1 stop4h 26m
American Airlines
월 6/13:25 pm
CLT
- ORD
Nonstop2h 18m
American Airlines
Deal found 5/3![American Airlines logo]()
$307
This Frontier deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/227:52 pm
ORD
- CLT
1 stop11h 01m
Frontier
일 5/2410:58 am
CLT
- ORD
1 stop8h 46m
Frontier
Deal found 5/3![Frontier logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 7/188:05 am
ORD
- SAV
1 stop6h 46m
Multiple Airlines
토 7/2512:19 pm
SAV
- ORD
1 stop25h 06m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 7/167:08 am
ORD
- GSP
Nonstop2h 06m
United Airlines
일 7/196:00 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 4/29![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 7/39:48 am
ORD
- CLT
1 stop5h 30m
Delta
토 7/118:05 am
CLT
- ORD
1 stop7h 20m
Delta
Deal found 4/29![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 6/210:05 am
MDW
- CHS
2 stops7h 30m
Southwest
화 6/98:20 am
CHS
- MDW
2 stops6h 45m
Southwest
Deal found 5/2![Southwest logo]()
$281
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 8/16:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
토 8/86:00 am
CLT
- ORD
1 stop6h 53m
United Airlines
Deal found 5/1![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/237:00 am
ORD
- GSP
1 stop3h 55m
Delta
토 5/308:45 am
GSP
- ORD
1 stop5h 16m
Delta
Deal found 4/30![Delta logo]()
$282
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2911:55 am
ORD
- CHS
1 stop4h 53m
American Airlines
월 6/17:19 pm
CHS
- ORD
1 stop6h 23m
American Airlines
Deal found 5/3![American Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 7/16:25 pm
ORD
- CHS
Nonstop2h 23m
United Airlines
수 7/86:00 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 4/29![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 6/248:20 am
MDW
- SAV
2 stops8h 25m
Southwest
화 6/306:45 am
SAV
- MDW
2 stops7h 50m
Southwest
Deal found 4/30![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 6/277:01 am
ORD
- GSP
1 stop4h 05m
Delta
월 6/297:10 am
GSP
- ORD
1 stop6h 54m
Delta
Deal found 4/29![Delta logo]()
$282
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 6/77:29 pm
ORD
- CHS
Nonstop2h 20m
American Airlines
화 6/912:58 pm
CHS
- ORD
1 stop4h 45m
American Airlines
Deal found 5/3![American Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 7/117:00 am
ORD
- GSP
1 stop4h 14m
Delta
일 7/1211:38 am
GSP
- ORD
1 stop6h 34m
Delta
Deal found 5/2![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 7/215:35 am
CVG
- SAV
2 stops7h 05m
Southwest
금 7/243:55 pm
SAV
- CVG
2 stops8h 30m
Southwest
Deal found 5/3![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 6/97:11 am
ORD
- MYR
Nonstop2h 33m
United Airlines
월 6/1510:34 am
MYR
- ORD
1 stop7h 28m
United Airlines
Deal found 4/29![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 6/29:49 am
ORD
- HHH
1 stop4h 44m
Delta
화 6/94:15 pm
HHH
- ORD
1 stop7h 19m
Delta
Deal found 4/29![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 6/57:45 pm
MDW
- CHS
Nonstop2h 05m
Southwest
화 6/94:15 pm
CHS
- MDW
1 stop6h 45m
Southwest
Deal found 4/30![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 7/187:02 am
ORD
- HHH
1 stop7h 51m
American Airlines
토 7/254:28 pm
HHH
- ORD
1 stop6h 14m
American Airlines
Deal found 5/3![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 7/36:00 am
CVG
- SAV
2 stops8h 43m
United Airlines
화 7/711:30 am
SAV
- CVG
1 stop5h 19m
United Airlines
Deal found 5/1![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 5/256:06 pm
ORD
- MYR
1 stop4h 52m
Delta
토 5/3011:28 am
MYR
- ORD
1 stop8h 41m
Delta
Deal found 4/30![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 6/77:45 pm
MDW
- CHS
Nonstop2h 05m
Southwest
화 6/98:15 pm
CHS
- MDW
1 stop3h 55m
Southwest
Deal found 5/3![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/97:07 am
ORD
- CLT
Nonstop2h 23m
United Airlines
토 5/95:28 pm
CLT
- ORD
Nonstop2h 25m
United Airlines
Deal found 5/3![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/235:44 pm
CVG
- SAV
1 stop3h 16m
Delta
목 5/286:33 pm
SAV
- CVG
1 stop3h 56m
Delta
Deal found 4/28![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 6/276:10 pm
MDW
- CHS
Nonstop2h 05m
Southwest
수 7/11:50 pm
CHS
- MDW
1 stop6h 15m
Southwest
Deal found 5/1![Southwest logo]()
$331
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 6/156:48 am
ORD
- CLT
Nonstop2h 14m
United Airlines
목 6/186:15 am
CLT
- ORD
Nonstop2h 15m
United Airlines
Deal found 4/29![United Airlines logo]()
$323
Last-minute flights from Indiana to South CarolinaDiscover last-minute flight deals from Indiana to South Carolina. Data last updated 5월 4, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to South Carolina. Data last updated 5월 4, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 5/149:07 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 5/232:56 pm
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$128
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
목 5/147:30 am
ORD
- CLT
1 stop9h 18m
Frontier
토 5/237:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/29![Frontier logo]()
$160
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/179:07 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 5/2310:27 am
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$136
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/2312:29 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
금 5/297:33 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$131
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2910:03 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
월 6/17:33 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$117
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2910:03 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
일 5/319:11 pm
SAV
- CVG
Nonstop1h 42m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$123
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/3012:29 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
목 6/47:30 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$112
This Cheapflightsfares deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 5/3012:29 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
월 6/17:33 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$129
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/316:44 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
금 6/56:00 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$119
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 6/128:46 am
CVG
- SAV
Nonstop1h 35m
Allegiant Air
금 6/196:15 am
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$137
This Cheapflightsfares deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 6/216:33 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 6/278:48 pm
SAV
- CVG
Nonstop1h 41m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
토 6/276:23 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
토 7/49:09 pm
SAV
- CVG
Nonstop1h 40m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$135
One-way flights from Indiana to South CarolinaSearch for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated 5월 4, 2026.
Search for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated 5월 4, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 7/268:42 pm
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$49
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/2910:03 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$55
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 7/208:30 am
CVG
- SAV
Nonstop1h 36m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/316:44 pm
CVG
- SAV
Nonstop1h 37m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$61
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 5/109:07 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 4/29![Allegiant Air logo]()
$62
This Super.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
금 5/229:18 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$63
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 5/2510:02 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 4/30![Allegiant Air logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
일 6/146:33 pm
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 5/2![Allegiant Air logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 8/267:55 am
ORD
- SAV
1 stop6h 56m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$74
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
화 5/2612:26 pm
IND
- CLT
1 stop11h 14m
Spirit Airlines
Deal found 4/30![Spirit Airlines logo]()
$74
This Cheapflightsfares deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
월 6/228:46 am
CVG
- SAV
Nonstop1h 35m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
수 6/177:52 am
ORD
- CLT
1 stop27h 22m
Frontier
Deal found 4/28![Frontier logo]()
$78
Find flight deals from Indiana to South Carolina
Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated 5월 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $112 (Cheapflightsfares) |
One-way from | $49 (Cheapflightsfares) |
Popular in | March |
Cheapest in | August |
Average price | $322 |
Good round-trip deal | $108 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 5월 4, 2026.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
수 6/17
6:55 am-9:55 am
Nonstop2h 00m
Greenville
수 6/24
5:43 pm-7:00 pm
Nonstop2h 17m
$255
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
목 7/16
7:08 am-10:14 am
Nonstop2h 06m
Greenville
일 7/19
6:00 am-7:20 am
Nonstop2h 20m
$269
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
토 8/1
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
토 8/8
6:00 am-11:53 am
1 stop6h 53m
$269
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
토 5/30
7:00 am-11:55 am
1 stop3h 55m
Greenville
화 6/2
3:00 pm-6:41 pm
1 stop4h 41m
$275
ChicagoCharleston
MDW - CHS
MDWCHS
Chicago Midway
목 6/4
8:10 am-11:25 am
Nonstop2h 15m
Charleston
월 6/8
4:45 pm-7:35 pm
1 stop3h 50m
$275
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
금 7/3
9:48 am-4:18 pm
1 stop5h 30m
Charlotte Douglas
토 7/11
8:05 am-2:25 pm
1 stop7h 20m
$279
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
수 7/1
6:25 pm-9:48 pm
Nonstop2h 23m
Charleston
수 7/8
6:00 am-7:33 am
Nonstop2h 33m
$279
ChicagoCharleston
MDW - CHS
MDWCHS
Chicago Midway
화 6/2
10:05 am-6:35 pm
2 stops7h 30m
Charleston
화 6/9
8:20 am-2:05 pm
2 stops6h 45m
$281
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
토 5/23
7:00 am-11:55 am
1 stop3h 55m
Greenville
토 5/30
8:45 am-1:01 pm
1 stop5h 16m
$282
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
토 6/27
7:01 am-12:06 pm
1 stop4h 05m
Greenville
월 6/29
7:10 am-1:04 pm
1 stop6h 54m
$282
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
IND-CLT
MDW-CHS
CVG-SAV
ORD-CHS
ORD-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to South Carolina
USIN-USSC
IND-CLT
MDW-CHS
CVG-SAV
ORD-CHS
How far ahead should I book a flight from Indiana to South Carolina?
The best time to book flights from Indiana to South Carolina is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Indiana to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $41). Flying from Indiana to South Carolina in January is currently the most expensive (average of $185). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to SC?
Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 5월 4, 2026.
One of the essential ways to save on airfare from Indiana to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 57% on airfare.
How much does it cost to fly round-trip from Indiana to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 5월 4, 2026.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Delta,United Airlines, andAllegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Indiana to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to South Carolina by cabin class
Find flights from Indiana to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and South Carolina flights
Browse other Indiana and South Carolina flight options. Last updated on 5월 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Indiana after your stay in South Carolina
Indiana to South Carolina flights
Consider these flights traveling from Indiana to South Carolina.
Top 6 airlines flying from Indiana to South Carolina
Discover the top 6 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 5월 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$61 | Average$131 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$95 | Average$177 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$166 | Average$404 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$183 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$342 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$247 | Average$408 | FlexibilityNo cancel fee | On-time63% |