$92+ Cheap flights from Indiana to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
Oct 11 — Oct 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Indiana to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Indiana to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Indiana to South CarolinaExplore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:38 pm -
1 stop6h 35m
Sun 11/155:38 pm -
1 stop18h 15m
Deal found 9/11![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:22 pm -
1 stop12h 43m
Tue 10/2012:05 pm -
1 stop7h 55m
Deal found 9/10![Frontier logo]()
$201
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:22 pm -
1 stop12h 43m
Tue 10/2012:05 pm -
1 stop7h 55m
Deal found 9/9![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:20 pm -
1 stop11h 15m
Tue 10/69:40 pm -
1 stop12h 45m
Deal found 9/9![Frontier logo]()
$211
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:21 am -
1 stop21h 14m
Thu 10/19:40 pm -
1 stop12h 45m
Deal found 9/9![Frontier logo]()
$216
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:25 pm -
1 stop23h 42m
Tue 12/89:34 am -
1 stop8h 51m
Deal found 9/9![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:06 pm -
1 stop11h 31m
Mon 11/29:32 am -
1 stop24h 58m
Deal found 9/11![Frontier logo]()
$227
This CheapOair deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:25 am -
1 stop21h 12m
Thu 10/294:47 pm -
1 stop22h 21m
Deal found 9/10![Frontier logo]()
$231
This Frontier deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:22 pm -
1 stop12h 43m
Thu 10/222:13 pm -
1 stop7h 14m
Deal found 9/8![Frontier logo]()
$232
This Priceline deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 pm -
1 stop6h 19m
Wed 12/210:00 am -
1 stop7h 59m
Deal found 9/11![Frontier logo]()
$234
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:21 am -
1 stop25h 14m
Wed 10/149:32 am -
1 stop10h 49m
Deal found 9/7![Frontier logo]()
$235
This Orbitz deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:50 pm -
1 stop25h 31m
Tue 9/299:32 am -
1 stop14h 27m
Deal found 9/9![Frontier logo]()
$240
Best flights from Indiana to South CarolinaDiscover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Indiana to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:45 am -
1 stop5h 20m
Sat 10/248:25 am -
Nonstop2h 00m
Deal found 9/8![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:58 pm -
Nonstop2h 06m
Mon 11/96:00 am -
1 stop6h 38m
Deal found 9/9![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:29 am -
1 stop6h 37m
Mon 10/265:01 pm -
1 stop4h 37m
Deal found 9/9![Delta logo]()
$289
This KAYAK deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:11 am -
1 stop6h 04m
Thu 10/17:49 am -
1 stop4h 52m
Deal found 9/10![American Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:05 am -
Nonstop1h 50m
Thu 10/1510:40 am -
1 stop5h 25m
Deal found 9/10![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:13 am -
2 stops9h 27m
Thu 10/294:56 pm -
1 stop5h 34m
Deal found 9/8![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:30 pm -
1 stop6h 29m
Tue 10/65:01 pm -
1 stop6h 32m
Deal found 9/10![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:17 pm -
Nonstop2h 00m
Tue 10/205:46 pm -
Nonstop2h 19m
Deal found 9/11![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:55 pm -
1 stop6h 32m
Sun 10/185:40 am -
1 stop3h 59m
Deal found 9/9![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:45 pm -
1 stop5h 45m
Mon 10/59:00 pm -
1 stop3h 55m
Deal found 9/9![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:15 am -
1 stop5h 45m
Wed 10/76:25 am -
1 stop6h 14m
Deal found 9/9![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:25 pm -
1 stop7h 02m
Sat 10/247:00 am -
1 stop6h 13m
Deal found 9/10![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:15 am -
1 stop5h 45m
Fri 10/24:23 pm -
1 stop7h 36m
Deal found 9/8![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:30 am -
2 stops8h 00m
Wed 11/2512:55 pm -
2 stops9h 10m
Deal found 9/8![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:55 pm -
1 stop4h 00m
Mon 10/56:36 pm -
1 stop5h 23m
Deal found 9/8![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:30 pm -
Nonstop2h 10m
Fri 10/237:15 pm -
Nonstop2h 10m
Deal found 9/9![Southwest logo]()
$338
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:25 am -
Nonstop1h 56m
Mon 11/97:43 pm -
1 stop5h 19m
Deal found 9/9![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:00 pm -
1 stop4h 12m
Mon 10/57:39 pm -
1 stop4h 05m
Deal found 9/8![Delta logo]()
$328
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 pm -
1 stop3h 20m
Mon 11/26:40 am -
1 stop5h 30m
Deal found 9/11![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:55 am -
Nonstop2h 25m
Sat 10/312:30 pm -
Nonstop2h 25m
Deal found 9/8![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:55 pm -
Nonstop1h 55m
Sun 11/228:10 am -
Nonstop2h 00m
Deal found 9/9![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:55 pm -
1 stop4h 02m
Sun 10/185:30 am -
1 stop3h 27m
Deal found 9/10![Delta logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops8h 27m
Fri 10/309:50 am -
1 stop4h 57m
Deal found 9/11![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:55 pm -
Nonstop1h 55m
Fri 11/138:10 am -
Nonstop2h 00m
Deal found 9/11![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:55 pm -
1 stop6h 56m
Mon 11/97:15 pm -
1 stop5h 39m
Deal found 9/7![Delta logo]()
$361
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:05 pm -
Nonstop2h 00m
Fri 11/278:10 am -
Nonstop2h 00m
Deal found 9/6![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
Nonstop2h 24m
Mon 10/1912:46 pm -
Nonstop2h 35m
Deal found 9/10![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:32 am -
1 stop6h 47m
Thu 11/263:00 pm -
1 stop5h 05m
Deal found 9/11![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:15 am -
2 stops12h 15m
Tue 10/67:25 am -
2 stops6h 30m
Deal found 9/9![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:03 pm -
Nonstop2h 12m
Mon 10/197:50 pm -
1 stop4h 42m
Deal found 9/6![United Airlines logo]()
$363
Last-minute flights from Indiana to South CarolinaDiscover last-minute flight deals from Indiana to South Carolina. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Indiana to South Carolina. Data last updated September 11, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:26 am -
1 stop22h 09m
Wed 9/309:32 am -
1 stop23h 59m
Deal found 9/8![Frontier logo]()
$240
This Orbitz deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:50 pm -
1 stop25h 31m
Tue 9/299:32 am -
1 stop14h 27m
Deal found 9/9![Frontier logo]()
$240
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:21 am -
1 stop21h 14m
Thu 10/19:40 pm -
1 stop12h 45m
Deal found 9/9![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:20 pm -
1 stop11h 15m
Tue 10/69:40 pm -
1 stop12h 45m
Deal found 9/9![Frontier logo]()
$211
This CheapOair deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:21 am -
1 stop21h 14m
Wed 10/214:47 pm -
1 stop19h 14m
Deal found 9/8![Frontier logo]()
$220
This CheapOair deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:21 am -
1 stop25h 14m
Wed 10/149:32 am -
1 stop10h 49m
Deal found 9/7![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:22 pm -
1 stop12h 43m
Tue 10/2012:05 pm -
1 stop7h 55m
Deal found 9/10![Frontier logo]()
$201
This Expedia deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:22 pm -
1 stop12h 43m
Tue 10/1312:05 pm -
1 stop7h 55m
Deal found 9/11![Frontier logo]()
$234
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:22 pm -
1 stop12h 43m
Tue 10/2012:05 pm -
1 stop7h 55m
Deal found 9/9![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:04 am -
1 stop7h 16m
Thu 10/225:14 pm -
1 stop23h 16m
Deal found 9/8![Multiple Airlines logo]()
$240
This Frontier deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:22 pm -
1 stop12h 43m
Thu 10/222:13 pm -
1 stop7h 14m
Deal found 9/8![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:06 pm -
1 stop11h 31m
Mon 11/29:32 am -
1 stop24h 58m
Deal found 9/11![Frontier logo]()
$227
One-way flights from Indiana to South CarolinaSearch for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
Search for one-way flight options from Indiana to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:52 pm -
2 stops17h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:59 pm -
2 stops17h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:48 pm -
2 stops36h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$102
This Super.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:38 pm -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:25 am -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:48 pm -
2 stops17h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$109
This Super.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:21 am -
1 stop21h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:59 pm -
2 stops36h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:52 pm -
2 stops36h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:41 pm -
1 stop15h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:59 pm -
2 stops36h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:04 am -
1 stop7h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$118
Find flight deals from Indiana to South Carolina
Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $201 (Kiwi.com) |
One-way from | $92 (Kiwi.com) |
Popular in | March |
Cheapest in | July |
Average price | $374 |
Good round-trip deal | $159 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Thu 9/17
11:30 am-5:00 pm
1 stop4h 30m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$135
ChicagoCharlotte
MDW Chicago Midway - CLT Charlotte Douglas
MDWCLT
Chicago Midway
Thu 10/1
6:05 am-1:30 pm
1 stop6h 25m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$139
ChicagoCharlotte
MDW Chicago Midway - CLT Charlotte Douglas
MDWCLT
Chicago Midway
Wed 9/30
6:05 am-1:30 pm
1 stop6h 25m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$139
ChicagoCharlotte
MDW Chicago Midway - CLT Charlotte Douglas
MDWCLT
Chicago Midway
Thu 11/26
12:05 pm-7:33 pm
1 stop6h 28m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$139
ChicagoMyrtle Beach
ORD Chicago O'Hare Intl - MYR Myrtle Beach Intl
ORDMYR
Chicago O'Hare Intl
Thu 11/5
8:00 am-8:03 am
1 stop23h 03m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$140
LouisvilleSavannah
SDF Louisville Intl - SAV Savannah/Hilton Head
SDFSAV
Louisville Intl
Tue 11/17
11:57 am-5:16 pm
1 stop5h 19m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Quickest round-trip
ChicagoCharlotte
MDW Chicago Midway - CLT Charlotte Douglas
MDWCLT
Chicago Midway
Fri 10/2
6:55 pm-9:45 pm
Nonstop1h 50m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$141
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Fri 10/23
6:03 pm-9:15 pm
Nonstop2h 12m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$141
ChicagoCharlotte
ORD Chicago O'Hare Intl - CLT Charlotte Douglas
ORDCLT
Chicago O'Hare Intl
Fri 11/13
6:29 am-9:46 am
Nonstop2h 17m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$141
LouisvilleSavannah
SDF Louisville Intl - SAV Savannah/Hilton Head
SDFSAV
Louisville Intl
Wed 11/18
5:40 am-3:55 pm
2 stops10h 15m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Indiana to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
IND-CLT
SDF-SAV
ORD-MYR
ORD-SAV
ORD-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indiana to South Carolina
USIN-USSC
IND-CLT
SDF-SAV
ORD-MYR
ORD-SAV
What is the cheapest month to book a flight from Indiana to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $259). Flying from Indiana to South Carolina in March is currently the most expensive (average of $414). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IN to SC?
Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2026.
One of the essential ways to save on airfare from Indiana to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 51% on airfare.
How much does it cost to fly round-trip from Indiana to South Carolina?
Airfare is below average for this route at the moment.
Indiana to South Carolina flights typically cost between $320 and $466 in October.The cheapest round-trip price found within the last 5 days was $218 on Multiple Airlines (Oct 20-Nov 3).
How far ahead should I book a flight from Indiana to South Carolina?
The best time to book flights from Indiana to South Carolina is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 11, 2026.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Indiana to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Indiana to South Carolina by cabin class
Find flights from Indiana to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Indiana and South Carolina flights
Browse other Indiana and South Carolina flight options. Last updated on September 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Indiana after your stay in South Carolina
Indiana to South Carolina flights
Consider these flights traveling from Indiana to South Carolina.
Top 5 airlines flying from Indiana to South Carolina
Discover the top 5 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$74 | Average$137 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$377 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$213 | Average$371 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$230 | Average$428 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$279 | Average$404 | FlexibilityNo cancel fee | On-time63% |