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South Carolina

$49+ Cheap flights from Indiana to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — CHS
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Indiana to South Carolina

Keep the following information in mind while searching for Indiana to South Carolina flight deals. Data was last updated July 1, 2025.

Round-trip from

$82
(Mytrip)

One-way from

$49
(Booking.com)

Popular in

December

Cheapest in

September

Average price

$271

Good round-trip deal

$54 or less

Good one-way deal

$49 or less
From Indiana to South Carolina
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One-way flight from Indiana to South Carolina
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Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Indiana to South Carolina.
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Price to beat on a one-way flight from Indiana to South Carolina.
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Find flight deals from Indiana to South Carolina

Cheapest flights from Indiana to South Carolina
Explore the most affordable flight options available from Indiana to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/151:47 pmCVG - MYR
Nonstop1h 32mAllegiant Air
Mon 8/189:51 pmMYR - CVG
Nonstop1h 41mAllegiant Air
Deal found 6/30$82
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1410:12 amORD - MYR
Nonstop2h 01mSpirit Airlines
Thu 8/212:18 pmMYR - ORD
Nonstop2h 25mSpirit Airlines
Deal found 6/30$106
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3111:11 amORD - MYR
Nonstop2h 00mMultiple Airlines
Mon 8/410:40 amMYR - ORD
1 stop9h 47mMultiple Airlines
Deal found 6/30$150
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/211:44 pmCVG - MYR
Nonstop1h 30mMultiple Airlines
Sat 7/266:10 amMYR - CVG
1 stop14h 23mMultiple Airlines
Deal found 6/30$151
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/811:05 amORD - SAV
Nonstop2h 29mUnited Airlines
Mon 8/1111:41 amSAV - ORD
Nonstop2h 34mUnited Airlines
Deal found 7/1$157
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:45 pmMDW - CLT
Nonstop1h 55mSouthwest
Mon 8/258:10 amCLT - MDW
2 stops6h 50mSouthwest
Deal found 7/1$158
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/88:26 amORD - SAV
Nonstop2h 11mAmerican Airlines
Mon 8/1112:29 pmSAV - ORD
Nonstop2h 31mAmerican Airlines
Deal found 7/1$158
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/296:00 amORD - CLT
1 stop9h 37mFrontier
Mon 9/111:57 amCLT - ORD
1 stop7h 31mFrontier
Deal found 6/30$159
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/162:06 pmORD - CLT
Nonstop2h 10mUnited Airlines
Tue 8/195:30 pmCLT - ORD
Nonstop2h 25mUnited Airlines
Deal found 7/1$160
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/157:35 amORD - CLT
Nonstop2h 08mAmerican Airlines
Fri 8/229:47 pmCLT - ORD
Nonstop2h 12mAmerican Airlines
Deal found 7/1$161
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1312:10 pmORD - CLT
1 stop9h 48mMultiple Airlines
Sun 8/1710:19 pmCLT - ORD
Nonstop2h 25mMultiple Airlines
Deal found 6/30$163
This Priceline deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/292:05 pmMDW - CLT
1 stop6h 56mFrontier
Sun 8/319:09 amCLT - MDW
1 stop9h 32mFrontier
Deal found 6/29$175

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Indiana to South Carolina that are best for you.

Fly from

Indiana

Fly to

South Carolina

Route

Depart

Return

Price

CincinnatiMyrtle Beach

CVG - MYR

CVGMYR

Cincinnati Cinci./N. Kentucky

Fri 8/15

1:47 pm-3:19 pm

Nonstop1h 32m

Myrtle Beach Intl

Mon 8/18

9:51 pm-11:32 pm

Nonstop1h 41m

$82

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 8/14

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

Thu 8/21

2:18 pm-3:43 pm

Nonstop2h 25m

$106

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 7/31

11:11 am-2:11 pm

Nonstop2h 00m

Myrtle Beach Intl

Mon 8/4

10:40 am-7:27 pm

1 stop9h 47m

$150

CincinnatiMyrtle Beach

CVG - MYR

CVGMYR

Cincinnati Cinci./N. Kentucky

Mon 7/21

1:44 pm-3:14 pm

Nonstop1h 30m

Myrtle Beach Intl

Sat 7/26

6:10 am-8:33 pm

1 stop14h 23m

$151

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Fri 8/8

11:05 am-2:34 pm

Nonstop2h 29m

Savannah/Hilton Head

Mon 8/11

11:41 am-1:15 pm

Nonstop2h 34m

$157

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 8/22

6:45 pm-9:40 pm

Nonstop1h 55m

Charlotte Douglas

Mon 8/25

8:10 am-2:00 pm

2 stops6h 50m

$158

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Fri 8/8

8:26 am-11:37 am

Nonstop2h 11m

Savannah/Hilton Head

Mon 8/11

12:29 pm-2:00 pm

Nonstop2h 31m

$158

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 8/29

6:00 am-4:37 pm

1 stop9h 37m

Charlotte Douglas

Mon 9/1

11:57 am-6:28 pm

1 stop7h 31m

$159

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 8/16

2:06 pm-5:16 pm

Nonstop2h 10m

Charlotte Douglas

Tue 8/19

5:30 pm-6:55 pm

Nonstop2h 25m

$160

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Fri 8/15

7:35 am-10:43 am

Nonstop2h 08m

Charlotte Douglas

Fri 8/22

9:47 pm-10:59 pm

Nonstop2h 12m

$161

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to South Carolina

What is the cheapest month to book a flight from Indiana to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SC?

Find hourly flight availability from Indiana to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

When flying from Indiana to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 1, 2025.
Read through reviews of airlines operating flights from Indiana to South Carolina, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,273 reviews
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,973 reviews
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,858 reviews
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
JetBlue
7.3
Good
2,919 reviews
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,273 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Indiana to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Indiana to South Carolina flight route?

    This flight path from Indiana to South Carolina was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Indiana to South Carolina one-way?

    $49 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Spirit Airlines and Frontier, with prices starting from $51 and $53, respectively.

  • Can I find deals for flights from Indiana to South Carolina that include hotel bookings?

    Yes. In addition to deals on Indiana to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to South Carolina.

  • Can I find deals for business class flights from Indiana to South Carolina?

    Yes. Cheapflights offers flight deals from Indiana to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Indiana to South Carolina (average of $217). Flying from Indiana to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Indiana to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to South Carolina

Discover the top 6 airlines that operate flights from Indiana to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$86Average$122FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$128Average$214FlexibilityNo cancel feeOn-time65%
DeltaCheapest$197Average$338FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$396FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$366FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$257Average$373FlexibilityNo cancel feeOn-time63%

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