$97+ Cheap flights from South Carolina to Indiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Indiana
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Cheapest flights from South Carolina to IndianaExplore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:12 pm -
2 stops18h 50m
Tue 11/171:33 pm -
1 stop19h 40m
Deal found 9/26![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:00 pm -
2 stops27h 57m
Tue 11/311:25 am -
1 stop21h 13m
Deal found 9/29![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:00 pm -
1 stop19h 30m
Wed 10/287:52 pm -
2 stops23h 45m
Deal found 9/27![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops12h 57m
Fri 11/62:19 pm -
1 stop18h 19m
Deal found 9/27![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:00 pm -
1 stop19h 30m
Sat 11/71:47 pm -
2 stops23h 50m
Deal found 9/27![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:53 pm -
1 stop22h 50m
Mon 11/97:52 pm -
2 stops39h 52m
Deal found 9/27![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:58 pm -
2 stops16h 04m
Mon 11/26:00 am -
1 stop26h 38m
Deal found 9/25![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:45 am -
2 stops11h 47m
Sat 12/511:04 am -
1 stop21h 34m
Deal found 9/27![Multiple Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:07 am -
1 stop5h 55m
Mon 11/94:24 pm -
1 stop6h 05m
Deal found 9/28![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:50 am -
1 stop4h 05m
Tue 11/39:40 am -
2 stops8h 45m
Deal found 9/28![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:37 pm -
1 stop6h 26m
Sat 11/711:25 am -
1 stop4h 42m
Deal found 9/28![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
2 stops10h 47m
Sat 11/147:09 am -
2 stops10h 02m
Deal found 9/29![United Airlines logo]()
$282
Best flights from South Carolina to IndianaDiscover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:12 pm -
1 stop4h 15m
Sat 11/146:00 am -
1 stop3h 48m
Deal found 9/29![American Airlines logo]()
$271
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:27 am -
1 stop6h 14m
Sat 11/149:10 am -
2 stops8h 01m
Deal found 9/29![United Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:40 am -
1 stop4h 45m
Mon 11/96:26 pm -
1 stop4h 30m
Deal found 9/29![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:05 am -
1 stop3h 20m
Mon 11/95:30 pm -
2 stops5h 30m
Deal found 9/29![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:32 pm -
1 stop13h 54m
Wed 10/217:59 pm -
2 stops21h 19m
Deal found 9/29![Multiple Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:12 am -
1 stop4h 14m
Mon 11/94:24 pm -
1 stop6h 05m
Deal found 9/25![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:45 am -
1 stop3h 45m
Mon 11/25:30 pm -
1 stop4h 45m
Deal found 9/25![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:05 pm -
1 stop5h 20m
Tue 10/2712:58 pm -
1 stop3h 37m
Deal found 9/28![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:18 pm -
1 stop6h 10m
Tue 1/56:15 pm -
1 stop5h 40m
Deal found 9/24![American Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:12 am -
2 stops9h 35m
Sun 11/16:40 am -
1 stop4h 41m
Deal found 9/24![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:19 pm -
1 stop4h 05m
Tue 12/18:00 am -
1 stop5h 14m
Deal found 9/24![Delta logo]()
$316
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:00 pm -
1 stop11h 20m
Sat 11/76:40 am -
2 stops9h 20m
Deal found 9/27![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:21 pm -
2 stops9h 28m
Wed 11/410:03 am -
1 stop4h 14m
Deal found 9/29![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:28 am -
1 stop6h 19m
Sun 11/16:00 am -
1 stop3h 30m
Deal found 9/28![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:05 pm -
1 stop4h 40m
Thu 10/296:45 am -
2 stops12h 40m
Deal found 9/24![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:31 pm -
1 stop6h 08m
Mon 1/185:10 am -
1 stop4h 41m
Deal found 9/26![United Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:54 pm -
1 stop4h 05m
Sun 12/1310:20 am -
1 stop4h 02m
Deal found 9/29![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
2 stops7h 20m
Tue 1/56:45 am -
2 stops6h 30m
Deal found 9/28![Southwest logo]()
$328
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/263:39 pm -
1 stop6h 37m
Tue 1/54:15 pm -
1 stop6h 10m
Deal found 9/25![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:29 pm -
1 stop5h 17m
Mon 11/238:00 am -
1 stop6h 27m
Deal found 9/29![United Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:05 pm -
1 stop4h 40m
Tue 10/279:50 am -
2 stops10h 35m
Deal found 9/26![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:08 pm -
1 stop3h 51m
Wed 10/215:27 pm -
1 stop6h 32m
Deal found 9/29![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1010:10 am -
1 stop6h 27m
Mon 2/1512:13 pm -
1 stop5h 44m
Deal found 9/29![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:55 pm -
1 stop4h 25m
Sun 11/85:30 am -
1 stop4h 35m
Deal found 9/27![Southwest logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:52 pm -
1 stop4h 07m
Sun 11/156:00 am -
1 stop5h 21m
Deal found 9/25![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 am -
1 stop6h 47m
Mon 10/196:14 pm -
1 stop5h 33m
Deal found 9/29![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/186:45 am -
1 stop6h 01m
Mon 3/224:15 pm -
1 stop3h 59m
Deal found 9/25![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
1 stop5h 05m
Sun 11/16:50 am -
2 stops6h 10m
Deal found 9/27![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1012:24 pm -
2 stops9h 30m
Mon 2/158:15 pm -
1 stop4h 20m
Deal found 9/29![United Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/294:13 pm -
1 stop5h 59m
Sun 11/16:32 am -
2 stops8h 58m
Deal found 9/29![Delta logo]()
$360
Last-minute flights from South Carolina to IndianaDiscover last-minute flight deals from South Carolina to Indiana. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indiana. Data last updated September 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:33 pm -
1 stop4h 04m
Mon 10/261:58 pm -
1 stop5h 55m
Deal found 9/27![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:33 pm -
1 stop4h 04m
Sat 10/247:58 pm -
1 stop3h 23m
Deal found 9/28![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:27 pm -
1 stop19h 03m
Wed 10/2811:25 am -
1 stop21h 13m
Deal found 9/28![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:00 pm -
2 stops27h 57m
Tue 11/311:25 am -
1 stop21h 13m
Deal found 9/29![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:00 pm -
1 stop19h 30m
Wed 10/287:52 pm -
2 stops23h 45m
Deal found 9/27![Multiple Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:22 am -
1 stop5h 54m
Tue 11/36:32 pm -
1 stop3h 57m
Deal found 9/28![American Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:50 am -
1 stop4h 05m
Tue 11/39:40 am -
2 stops8h 45m
Deal found 9/28![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:13 pm -
2 stops20h 44m
Sat 10/3112:38 pm -
1 stop6h 34m
Deal found 9/27![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:58 pm -
2 stops16h 04m
Mon 11/26:00 am -
1 stop26h 38m
Deal found 9/25![Multiple Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:22 am -
1 stop5h 54m
Sat 10/316:00 am -
1 stop5h 13m
Deal found 9/26![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:55 pm -
2 stops8h 50m
Sat 10/315:20 am -
1 stop6h 50m
Deal found 9/26![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:45 am -
1 stop3h 45m
Mon 11/25:30 pm -
1 stop4h 45m
Deal found 9/28![Southwest logo]()
$304
One-way flights from South Carolina to IndianaSearch for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:18 pm -
2 stops27h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:28 am -
2 stops31h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
2 stops13h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:27 pm -
1 stop19h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:28 am -
2 stops31h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/273:00 pm -
1 stop19h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$133
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:45 am -
2 stops36h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$137
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Delta logo]()
$140
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:55 pm -
2 stops8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:57 pm -
1 stop19h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$142
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:00 am -
1 stop5h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$149
Find flight deals from South Carolina to Indiana
Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $97 (Kiwi.com) |
Popular in | April |
Cheapest in | June |
Average price | $476 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Tue 10/20
11:28 am-7:04 pm
2 stops31h 36m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$103
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Sat 10/24
6:30 am-10:03 am
1 stop3h 33m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/22
6:30 am-1:08 pm
1 stop6h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Mon 10/19
7:14 pm-12:25 am
1 stop5h 11m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Tue 10/20
6:00 am-2:06 pm
1 stop8h 06m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Thu 10/22
7:00 am-11:49 am
1 stop4h 49m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Quickest round-trip
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Tue 10/27
5:00 pm-8:28 pm
1 stop3h 28m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sat 12/5
7:00 am-12:59 pm
1 stop5h 59m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Myrtle BeachIndianapolis
MYR Myrtle Beach Intl - IND Indianapolis
MYRIND
Myrtle Beach Intl
Thu 10/22
3:55 pm-12:15 am
2 stops8h 20m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Wed 10/21
6:00 am-2:22 pm
2 stops8h 22m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
GSP-IND
MYR-IND
CHS-IND
HHH-IND
CAE-IND
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indiana
USSC-USIN
GSP-IND
MYR-IND
CHS-IND
HHH-IND
What is the cheapest month to book a flight from South Carolina to Indiana?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $306). Flying from South Carolina to Indiana in April is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IN?
Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 29, 2026.
One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 42% on airfare.
How much does it cost to fly round-trip from South Carolina to Indiana?
Airfare is below average for this route at the moment.
South Carolina to Indiana flights typically cost between $352 and $474 in October.The cheapest round-trip price found within the last 5 days was $204 on Multiple Airlines (Oct 21-Oct 26).
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated September 29, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indiana by cabin class
Find flights from South Carolina to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Indiana flights
Browse other South Carolina and Indiana flight options. Last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to South Carolina after your stay in Indiana
South Carolina to Indiana flights
Consider these flights traveling from South Carolina to Indiana.
Top 5 airlines flying from South Carolina to Indiana
Discover the top 5 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$151 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$408 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$420 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$388 | FlexibilityNo cancel fee | On-time69% |