$92+ Cheap flights from South Carolina to Indiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to IndianaExplore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:43 am -
1 stop9h 00m
Thu 12/3111:08 am -
1 stop21h 05m
Deal found 11/9![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:43 am -
1 stop9h 00m
Tue 12/227:43 pm -
2 stops37h 49m
Deal found 11/8![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:03 pm -
1 stop19h 50m
Thu 12/37:52 pm -
2 stops15h 52m
Deal found 11/5![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:42 pm -
1 stop27h 13m
Wed 12/2311:08 am -
1 stop20h 45m
Deal found 11/8![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:58 pm -
1 stop16h 26m
Mon 12/74:55 pm -
1 stop15h 43m
Deal found 11/5![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:42 pm -
1 stop27h 13m
Thu 12/247:43 pm -
2 stops24h 29m
Deal found 11/8![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:03 pm -
1 stop19h 50m
Sun 11/2210:56 am -
1 stop21h 07m
Deal found 11/8![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:42 pm -
1 stop26h 38m
Fri 11/276:53 pm -
1 stop13h 01m
Deal found 11/8![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:42 pm -
1 stop21h 43m
Mon 12/147:39 pm -
2 stops19h 50m
Deal found 11/9![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:15 pm -
1 stop20h 34m
Mon 12/74:55 pm -
1 stop15h 43m
Deal found 11/5![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:15 pm -
1 stop24h 28m
Tue 12/297:43 pm -
2 stops36h 55m
Deal found 11/9![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:15 pm -
1 stop20h 34m
Sun 12/138:27 pm -
2 stops36h 11m
Deal found 11/6![Multiple Airlines logo]()
$261
Best flights from South Carolina to IndianaDiscover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:03 pm -
1 stop5h 39m
Mon 1/46:00 am -
1 stop4h 45m
Deal found 11/5![Delta logo]()
$271
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:47 pm -
1 stop5h 54m
Thu 12/106:00 am -
1 stop4h 30m
Deal found 11/5![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:35 pm -
1 stop20h 06m
Tue 1/122:30 pm -
1 stop18h 08m
Deal found 11/9![Multiple Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:05 am -
1 stop5h 25m
Thu 12/106:00 am -
2 stops8h 10m
Deal found 11/5![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:57 pm -
1 stop5h 02m
Sun 12/67:35 am -
1 stop6h 25m
Deal found 11/5![United Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:40 am -
1 stop3h 28m
Thu 12/36:30 pm -
1 stop5h 17m
Deal found 11/5![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:03 pm -
2 stops7h 11m
Tue 12/159:00 am -
1 stop4h 26m
Deal found 11/9![United Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:09 pm -
1 stop4h 22m
Tue 1/56:00 am -
2 stops6h 15m
Deal found 11/5![American Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:10 am -
1 stop3h 55m
Tue 12/225:40 am -
1 stop4h 20m
Deal found 11/5![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop3h 38m
Tue 12/156:00 am -
1 stop5h 13m
Deal found 11/9![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:04 pm -
1 stop4h 26m
Sat 12/57:15 am -
2 stops7h 09m
Deal found 11/8![United Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:09 pm -
1 stop13h 44m
Tue 12/2910:01 am -
1 stop11h 44m
Deal found 11/9![Multiple Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/24:55 pm -
1 stop5h 23m
Wed 3/37:00 am -
2 stops8h 14m
Deal found 11/5![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1312:55 pm -
2 stops8h 10m
Tue 2/167:05 am -
2 stops8h 15m
Deal found 11/9![Southwest logo]()
$343
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:00 am -
1 stop6h 13m
Sun 12/206:00 pm -
1 stop4h 11m
Deal found 11/9![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/135:05 pm -
1 stop4h 27m
Tue 2/169:00 am -
1 stop4h 26m
Deal found 11/9![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:50 pm -
2 stops8h 00m
Tue 12/156:00 am -
2 stops8h 10m
Deal found 11/9![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
2 stops10h 41m
Fri 12/114:36 pm -
1 stop4h 45m
Deal found 11/8![United Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:28 pm -
1 stop4h 08m
Sun 11/228:06 pm -
1 stop3h 51m
Deal found 11/6![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:25 pm -
2 stops7h 25m
Thu 12/108:15 am -
2 stops10h 10m
Deal found 11/5![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:59 pm -
1 stop4h 35m
Sun 1/36:32 pm -
1 stop4h 30m
Deal found 11/7![Delta logo]()
$360
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:17 pm -
1 stop4h 22m
Mon 12/144:57 pm -
1 stop6h 42m
Deal found 11/8![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:15 pm -
1 stop21h 05m
Wed 11/2510:30 pm -
2 stops34h 15m
Deal found 11/8![Multiple Airlines logo]()
$461
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/145:33 pm -
1 stop4h 25m
Mon 1/189:15 am -
1 stop4h 35m
Deal found 11/7![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:05 pm -
1 stop4h 40m
Fri 12/255:30 am -
1 stop5h 15m
Deal found 11/6![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
1 stop6h 27m
Thu 12/316:00 am -
1 stop4h 01m
Deal found 11/7![Delta logo]()
$360
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:55 pm -
1 stop7h 04m
Fri 12/2511:46 am -
2 stops12h 13m
Deal found 11/7![United Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:47 am -
2 stops7h 23m
Mon 12/74:16 pm -
1 stop4h 44m
Deal found 11/9![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:30 pm -
2 stops9h 20m
Mon 12/79:40 am -
2 stops10h 25m
Deal found 11/5![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:00 pm -
1 stop16h 04m
Fri 1/18:00 am -
1 stop6h 46m
Deal found 11/9![Delta logo]()
$371
Last-minute flights from South Carolina to IndianaDiscover last-minute flight deals from South Carolina to Indiana. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indiana. Data last updated November 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:03 pm -
1 stop19h 50m
Sun 11/2210:56 am -
1 stop21h 07m
Deal found 11/8![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:03 pm -
1 stop19h 50m
Thu 12/37:52 pm -
2 stops15h 52m
Deal found 11/5![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:42 pm -
1 stop26h 38m
Fri 11/276:53 pm -
1 stop13h 01m
Deal found 11/8![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:15 pm -
1 stop20h 34m
Mon 12/74:55 pm -
1 stop15h 43m
Deal found 11/5![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:58 pm -
1 stop16h 26m
Mon 12/74:55 pm -
1 stop15h 43m
Deal found 11/5![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:15 pm -
1 stop20h 34m
Sun 12/138:27 pm -
2 stops36h 11m
Deal found 11/6![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:42 pm -
1 stop21h 43m
Mon 12/147:39 pm -
2 stops19h 50m
Deal found 11/9![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:43 am -
1 stop9h 00m
Tue 12/227:43 pm -
2 stops37h 49m
Deal found 11/8![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:42 pm -
1 stop27h 13m
Wed 12/2311:08 am -
1 stop20h 45m
Deal found 11/8![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:42 pm -
1 stop27h 13m
Thu 12/247:43 pm -
2 stops24h 29m
Deal found 11/8![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:15 pm -
1 stop24h 28m
Tue 12/297:43 pm -
2 stops36h 55m
Deal found 11/9![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/248:43 am -
1 stop9h 00m
Thu 12/3111:08 am -
1 stop21h 05m
Deal found 11/9![Multiple Airlines logo]()
$201
One-way flights from South Carolina to IndianaSearch for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:09 pm -
1 stop16h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/103:31 pm -
1 stop19h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/183:15 pm -
1 stop28h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Allegiant Air logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:42 pm -
2 stops26h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:57 pm -
1 stop24h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$140
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:54 am -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:09 pm -
1 stop21h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/143:31 pm -
1 stop29h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Allegiant Air logo]()
$149
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:00 am -
1 stop5h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Delta logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/610:15 pm -
1 stop20h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$154
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/18:10 am -
1 stop5h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:04 am -
1 stop8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$156
Find flight deals from South Carolina to Indiana
Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $201 (Kiwi.com) |
One-way from | $92 (Kiwi.com) |
Popular in | August |
Cheapest in | October |
Average price | $365 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Wed 12/9
6:40 am-12:25 pm
3 stops29h 45m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Mon 11/23
4:57 pm-5:20 pm
1 stop24h 23m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sat 12/5
10:54 am-4:22 pm
1 stop5h 28m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sat 12/5
7:00 am-12:59 pm
1 stop5h 59m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Sun 12/6
10:15 pm-6:49 pm
1 stop20h 34m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$154
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Sat 2/20
6:00 am-12:41 pm
1 stop6h 41m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
CharlestonIndianapolis
CHS Charleston - IND Indianapolis
CHSIND
Charleston
Fri 1/1
8:10 am-1:48 pm
1 stop5h 38m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sun 12/6
7:05 am-12:24 pm
1 stop5h 19m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$169
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Sun 1/10
10:12 am-1:45 pm
3 stops51h 33m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
GreenvilleIndianapolis
GSP Greenville - IND Indianapolis
GSPIND
Greenville
Fri 12/18
8:52 pm-4:50 pm
3 stops19h 58m
Indianapolis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$186
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
GSP-IND
MYR-IND
CHS-IND
MYR-SBN
CHS-SBN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indiana
USSC-USIN
GSP-IND
MYR-IND
CHS-IND
MYR-SBN
What is the cheapest month to book a flight from South Carolina to Indiana?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $326). Flying from South Carolina to Indiana in September is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IN?
Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2026.
One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 42% on airfare.
How much does it cost to fly round-trip from South Carolina to Indiana?
Airfare is below average for this route at the moment.
South Carolina to Indiana flights typically cost between $308 and $464 in December.The cheapest round-trip price found within the last 5 days was $232 on Multiple Airlines (Dec 4-Dec 7).
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated November 10, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.4
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indiana by cabin class
Find flights from South Carolina to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Indiana flights
Browse other South Carolina and Indiana flight options. Last updated on November 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to South Carolina after your stay in Indiana
South Carolina to Indiana flights
Consider these flights traveling from South Carolina to Indiana.
Top 5 airlines flying from South Carolina to Indiana
Discover the top 5 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$133 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$412 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$403 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$396 | FlexibilityNo cancel fee | On-time69% |