$81+ Cheap flights from South Carolina to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Jun 11 — Jun 181
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indiana with Cheapflights
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Cheapest flights from South Carolina to IndianaExplore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:10 am
CLT
- IND
1 stop6h 34m
Frontier
Wed 6/241:44 pm
IND
- CLT
1 stop9h 57m
Frontier
Deal found 5/9![Frontier logo]()
$190
This Expedia deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Tue 6/164:59 pm
ORD
- CLT
1 stop17h 35m
Frontier
Deal found 5/12![Frontier logo]()
$190
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:58 pm
CLT
- CVG
1 stop27h 48m
Frontier
Tue 6/169:30 pm
CVG
- CLT
1 stop14h 04m
Frontier
Deal found 5/11![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:05 am
SAV
- ORD
1 stop27h 20m
Multiple Airlines
Wed 9/27:55 am
ORD
- SAV
1 stop6h 56m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Wed 6/175:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Deal found 5/10![Frontier logo]()
$203
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Sat 6/135:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Deal found 5/11![Frontier logo]()
$204
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:58 pm
CLT
- CVG
1 stop17h 09m
Frontier
Wed 6/39:30 pm
CVG
- CLT
1 stop19h 13m
Frontier
Deal found 5/11![Frontier logo]()
$204
This Priceline deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:45 am
CLT
- IND
1 stop6h 09m
Frontier
Mon 6/151:44 pm
IND
- CLT
1 stop10h 02m
Frontier
Deal found 5/10![Frontier logo]()
$210
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Thu 8/69:34 pm
ORD
- CLT
1 stop12h 42m
Frontier
Deal found 5/10![Frontier logo]()
$210
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
CLT
- CVG
1 stop8h 32m
Frontier
Wed 6/249:30 pm
CVG
- CLT
1 stop14h 04m
Frontier
Deal found 5/9![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Sat 7/188:05 pm
ORD
- CLT
1 stop11h 34m
Frontier
Deal found 5/7![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Thu 7/1612:44 am
ORD
- CLT
1 stop11h 08m
Frontier
Deal found 5/10![Frontier logo]()
$212
Best flights from South Carolina to IndianaDiscover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:57 pm
MYR
- ORD
1 stop5h 02m
Delta
Tue 6/166:22 pm
ORD
- MYR
1 stop4h 37m
Delta
Deal found 5/8![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:30 am
SAV
- ORD
Nonstop2h 37m
United Airlines
Tue 6/236:20 pm
ORD
- SAV
Nonstop2h 36m
United Airlines
Deal found 5/10![United Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:06 am
CHS
- ORD
1 stop5h 19m
American Airlines
Thu 8/137:52 am
ORD
- CHS
1 stop6h 46m
American Airlines
Deal found 5/6![American Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:25 pm
GSP
- MDW
1 stop6h 05m
Southwest
Mon 6/13:50 pm
MDW
- GSP
1 stop5h 45m
Southwest
Deal found 5/8![Southwest logo]()
$282
This Contour deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Mon 7/2011:20 am
ORD
- CLT
1 stop4h 40m
Contour
Deal found 5/10![Contour logo]()
$312
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:41 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Mon 6/16:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Deal found 5/8![United Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:15 pm
MYR
- ORD
1 stop7h 15m
Delta
Tue 9/295:30 am
ORD
- MYR
1 stop7h 08m
Delta
Deal found 5/9![Delta logo]()
$264
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:44 pm
CHS
- ORD
Nonstop2h 34m
American Airlines
Tue 7/77:45 pm
ORD
- CHS
Nonstop2h 24m
American Airlines
Deal found 5/6![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:40 pm
GSP
- MDW
1 stop3h 35m
Southwest
Sat 6/136:35 am
MDW
- GSP
1 stop4h 40m
Southwest
Deal found 5/7![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:30 pm
MYR
- ORD
Nonstop2h 34m
United Airlines
Wed 6/107:03 am
ORD
- MYR
Nonstop2h 33m
United Airlines
Deal found 5/11![United Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:05 am
CLT
- ORD
1 stop5h 24m
Delta
Wed 5/276:06 pm
ORD
- CLT
1 stop4h 47m
Delta
Deal found 5/7![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:30 pm
CLT
- MDW
Nonstop2h 00m
Southwest
Wed 8/268:45 am
MDW
- CLT
Nonstop2h 10m
Southwest
Deal found 5/7![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:00 am
SAV
- ORD
Nonstop2h 39m
United Airlines
Wed 6/108:40 am
ORD
- SAV
1 stop5h 03m
United Airlines
Deal found 5/10![United Airlines logo]()
$267
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:10 am
GSP
- ORD
1 stop4h 25m
Delta
Sat 7/117:00 am
ORD
- GSP
1 stop4h 14m
Delta
Deal found 5/11![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:30 am
GSP
- MDW
2 stops6h 35m
Southwest
Sat 6/63:30 pm
MDW
- GSP
1 stop3h 30m
Southwest
Deal found 5/9![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:41 pm
CAE
- ORD
Nonstop2h 24m
United Airlines
Thu 6/255:55 pm
ORD
- CAE
Nonstop2h 21m
United Airlines
Deal found 5/11![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:44 am
GSP
- ORD
1 stop5h 29m
Delta
Sun 7/56:35 am
ORD
- GSP
1 stop4h 43m
Delta
Deal found 5/11![Delta logo]()
$282
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:55 pm
GSP
- MDW
2 stops9h 00m
Southwest
Fri 6/127:15 am
MDW
- GSP
1 stop4h 00m
Southwest
Deal found 5/6![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Sat 6/66:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Deal found 5/9![United Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:13 pm
CAE
- ORD
Nonstop2h 31m
American Airlines
Sat 7/115:07 am
ORD
- CAE
1 stop6h 13m
American Airlines
Deal found 5/6![American Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:01 pm
CAE
- ORD
1 stop6h 52m
Delta
Sun 7/195:30 am
ORD
- CAE
1 stop4h 37m
Delta
Deal found 5/11![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Fri 7/176:55 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 5/9![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:51 pm
CHS
- ORD
1 stop4h 49m
United Airlines
Mon 9/77:25 am
ORD
- CHS
Nonstop2h 31m
United Airlines
Deal found 5/8![United Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:50 pm
CAE
- ORD
1 stop7h 13m
Delta
Mon 6/15:30 am
ORD
- CAE
1 stop6h 44m
Delta
Deal found 5/9![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:50 am
CLT
- MDW
Nonstop1h 55m
Southwest
Wed 6/175:20 pm
MDW
- CLT
1 stop3h 45m
Southwest
Deal found 5/8![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:00 am
MYR
- ORD
1 stop5h 46m
United Airlines
Tue 9/297:04 am
ORD
- MYR
Nonstop2h 33m
United Airlines
Deal found 5/9![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:42 pm
GSP
- ORD
1 stop5h 17m
Delta
Sun 6/75:30 am
ORD
- GSP
1 stop5h 48m
Delta
Deal found 5/11![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:25 pm
GSP
- MDW
1 stop6h 05m
Southwest
Sun 5/2412:30 pm
MDW
- GSP
1 stop3h 45m
Southwest
Deal found 5/6![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:40 pm
GSP
- ORD
1 stop4h 46m
United Airlines
Mon 6/156:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Deal found 5/10![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:11 pm
CLT
- CVG
Nonstop1h 27m
American Airlines
Tue 6/169:13 am
CVG
- CLT
Nonstop1h 45m
American Airlines
Deal found 5/11![American Airlines logo]()
$458
Last-minute flights from South Carolina to IndianaDiscover last-minute flight deals from South Carolina to Indiana. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indiana. Data last updated May 12, 2026 and is based on user searches.
This Gotogate deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 pm
CLT
- ORD
1 stop17h 35m
Multiple Airlines
Wed 5/275:11 pm
ORD
- CLT
1 stop18h 01m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$232
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:58 pm
CLT
- CVG
1 stop17h 09m
Frontier
Wed 6/39:30 pm
CVG
- CLT
1 stop19h 13m
Frontier
Deal found 5/11![Frontier logo]()
$204
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:00 pm
CLT
- IND
1 stop24h 01m
Frontier
Tue 7/78:53 pm
IND
- CLT
1 stop24h 30m
Frontier
Deal found 5/9![Frontier logo]()
$218
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:14 pm
CLT
- IND
1 stop24h 40m
Frontier
Mon 6/87:32 pm
IND
- CLT
1 stop16h 02m
Frontier
Deal found 5/11![Frontier logo]()
$234
This Priceline deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:45 am
CLT
- IND
1 stop6h 09m
Frontier
Mon 6/151:44 pm
IND
- CLT
1 stop10h 02m
Frontier
Deal found 5/10![Frontier logo]()
$210
This Trip.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
CLT
- CVG
1 stop8h 32m
Frontier
Thu 6/183:47 pm
CVG
- CLT
1 stop7h 54m
Frontier
Deal found 5/11![Frontier logo]()
$226
This Trip.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:00 am
CLT
- CVG
1 stop8h 32m
Frontier
Fri 6/123:47 pm
CVG
- CLT
1 stop7h 59m
Frontier
Deal found 5/11![Frontier logo]()
$227
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
CLT
- CVG
1 stop8h 32m
Frontier
Wed 6/249:30 pm
CVG
- CLT
1 stop14h 04m
Frontier
Deal found 5/9![Frontier logo]()
$210
This Priceline deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
CLT
- IND
1 stop6h 44m
Frontier
Mon 6/151:44 pm
IND
- CLT
1 stop10h 02m
Frontier
Deal found 5/8![Frontier logo]()
$230
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:00 am
CLT
- IND
1 stop6h 44m
Frontier
Tue 6/167:08 pm
IND
- CLT
1 stop21h 45m
Frontier
Deal found 5/8![Frontier logo]()
$233
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:10 am
CLT
- IND
1 stop6h 34m
Frontier
Wed 6/241:44 pm
IND
- CLT
1 stop9h 57m
Frontier
Deal found 5/9![Frontier logo]()
$190
This Expedia deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:58 pm
CLT
- CVG
1 stop27h 48m
Frontier
Sun 6/213:47 pm
CVG
- CLT
1 stop7h 54m
Frontier
Deal found 5/11![Frontier logo]()
$230
One-way flights from South Carolina to IndianaSearch for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:34 pm
CHS
- ORD
1 stop7h 40m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$81
This Super.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/7![Frontier logo]()
$94
This Priceline deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:10 am
CLT
- IND
1 stop6h 34m
Frontier
Deal found 5/9![Frontier logo]()
$95
This Frontier deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/11![Frontier logo]()
$95
This Trip.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:00 pm
CLT
- CVG
1 stop10h 38m
Frontier
Deal found 5/7![Frontier logo]()
$100
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:14 pm
CLT
- IND
1 stop21h 52m
Frontier
Deal found 5/7![Frontier logo]()
$101
This Gotogate deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Deal found 5/11![Frontier logo]()
$101
This Frontier deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:00 pm
CLT
- CVG
1 stop10h 38m
Frontier
Deal found 5/9![Frontier logo]()
$101
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 pm
CLT
- ORD
1 stop25h 00m
Contour
Deal found 5/11![Contour logo]()
$105
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:05 pm
CLT
- ORD
1 stop23h 10m
Contour
Deal found 5/11![Contour logo]()
$106
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/10![Contour logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/71:19 pm
CLT
- IND
2 stops21h 46m
Frontier
Deal found 5/11![Frontier logo]()
$108
Find flight deals from South Carolina to Indiana
Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Priceline) |
One-way from | $81 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $404 |
Good round-trip deal | $110 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachChicago
MYR - ORD
MYRORD
Myrtle Beach Intl
Wed 6/10
7:57 pm-11:59 pm
1 stop5h 02m
Chicago O'Hare Intl
Tue 6/16
6:22 pm-11:59 pm
1 stop4h 37m
$237
SavannahChicago
SAV - ORD
SAVORD
Savannah/Hilton Head
Tue 6/16
11:30 am-1:07 pm
Nonstop2h 37m
Chicago O'Hare Intl
Tue 6/23
6:20 pm-9:56 pm
Nonstop2h 36m
$257
GreenvilleChicago
GSP - ORD
GSPORD
Greenville
Fri 5/29
5:41 pm-6:58 pm
Nonstop2h 17m
Chicago O'Hare Intl
Mon 6/1
6:55 am-9:55 am
Nonstop2h 00m
$262
Myrtle BeachChicago
MYR - ORD
MYRORD
Myrtle Beach Intl
Thu 9/24
2:15 pm-8:30 pm
1 stop7h 15m
Chicago O'Hare Intl
Tue 9/29
5:30 am-1:38 pm
1 stop7h 08m
$264
Myrtle BeachChicago
MYR - ORD
MYRORD
Myrtle Beach Intl
Thu 5/28
6:30 pm-8:04 pm
Nonstop2h 34m
Chicago O'Hare Intl
Wed 6/10
7:03 am-10:36 am
Nonstop2h 33m
$266
SavannahChicago
SAV - ORD
SAVORD
Savannah/Hilton Head
Wed 6/3
8:00 am-9:39 am
Nonstop2h 39m
Chicago O'Hare Intl
Wed 6/10
8:40 am-2:43 pm
1 stop5h 03m
$267
ColumbiaChicago
CAE - ORD
CAEORD
Columbia Metropolitan
Tue 6/9
5:41 pm-7:05 pm
Nonstop2h 24m
Chicago O'Hare Intl
Thu 6/25
5:55 pm-9:16 pm
Nonstop2h 21m
$269
GreenvilleChicago
GSP - ORD
GSPORD
Greenville
Wed 6/3
5:43 pm-7:00 pm
Nonstop2h 17m
Chicago O'Hare Intl
Sat 6/6
6:55 am-9:55 am
Nonstop2h 00m
$269
CharlestonChicago
CHS - ORD
CHSORD
Charleston
Wed 8/26
7:51 pm-11:40 pm
1 stop4h 49m
Chicago O'Hare Intl
Mon 9/7
7:25 am-10:56 am
Nonstop2h 31m
$275
Myrtle BeachChicago
MYR - ORD
MYRORD
Myrtle Beach Intl
Thu 9/24
10:00 am-2:46 pm
1 stop5h 46m
Chicago O'Hare Intl
Tue 9/29
7:04 am-10:37 am
Nonstop2h 33m
$278
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
CLT-IND
CLT-ORD
CLT-CVG
SAV-ORD
MYR-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indiana
USSC-USIN
CLT-IND
CLT-ORD
CLT-CVG
SAV-ORD
How far ahead should I book a flight from South Carolina to Indiana?
The price you pay for your flight from South Carolina to Indiana may vary depending on when you book. For the best chance of a lower fare, look to book 79 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from South Carolina to Indiana?
Currently, July is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $45). Flying from South Carolina to Indiana in March is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IN?
Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 12, 2026.
One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 27% on airfare.
How much does it cost to fly round-trip from South Carolina to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated May 12, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Delta,United Airlines, andAllegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.9
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indiana by cabin class
Find flights from South Carolina to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Indiana flights
Browse other South Carolina and Indiana flight options. Last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to South Carolina after your stay in Indiana
South Carolina to Indiana flights
Consider these flights traveling from South Carolina to Indiana.
Top 6 airlines flying from South Carolina to Indiana
Discover the top 6 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$45 | Average$138 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$83 | Average$188 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$179 | Average$330 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$189 | Average$376 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$190 | Average$346 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$389 | FlexibilityNo cancel fee | On-time71% |