Indiana

$84+ Cheap flights from South Carolina to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Jul 31 — Aug 71
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Cheap flight deals from South Carolina to Indiana

Cheapest flights from South Carolina to Indiana
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2026.

This Expedia deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:24 pm
CLT
-
IND
1 stop21h 24m
Frontier
Wed 8/1210:53 am
IND
-
CLT
1 stop20h 58m
Frontier
Deal found 6/30$210
This Frontier deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:24 pm
CLT
-
CVG
1 stop11h 18m
Frontier
Wed 8/129:23 pm
CVG
-
CLT
1 stop10h 28m
Frontier
Deal found 6/30$210
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:19 pm
SAV
-
ORD
1 stop24h 56m
Multiple Airlines
Sat 8/158:05 am
ORD
-
SAV
1 stop8h 50m
Multiple Airlines
Deal found 6/27$210
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:41 pm
CLT
-
CVG
1 stop18h 01m
Multiple Airlines
Fri 8/142:03 pm
CVG
-
CLT
1 stop7h 10m
Multiple Airlines
Deal found 6/30$211
This CheapOair deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:24 pm
CLT
-
IND
1 stop21h 24m
Frontier
Tue 8/188:49 pm
IND
-
CLT
1 stop19h 37m
Frontier
Deal found 6/27$220
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:46 am
CLT
-
CVG
1 stop10h 42m
Multiple Airlines
Sun 8/233:38 pm
CVG
-
CLT
1 stop29h 05m
Multiple Airlines
Deal found 6/26$227
This Frontier deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:24 pm
CLT
-
CVG
1 stop11h 22m
Frontier
Tue 7/287:15 am
CVG
-
CLT
1 stop9h 23m
Frontier
Deal found 6/30$230
This Frontier deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:24 pm
CLT
-
IND
1 stop5h 51m
Frontier
Sat 8/87:38 pm
IND
-
CLT
1 stop12h 13m
Frontier
Deal found 6/30$233
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:01 pm
CLT
-
CVG
1 stop6h 21m
Frontier
Tue 8/187:15 am
CVG
-
CLT
1 stop9h 43m
Frontier
Deal found 6/30$233
This Kiwi.com deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:38 pm
CLT
-
CVG
2 stops21h 35m
Multiple Airlines
Wed 7/298:00 am
CVG
-
CLT
1 stop13h 07m
Multiple Airlines
Deal found 6/27$234
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:53 pm
SAV
-
ORD
Nonstop2h 37m
United Airlines
Sat 8/155:55 pm
ORD
-
SAV
Nonstop2h 24m
United Airlines
Deal found 6/27$237
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:38 pm
CLT
-
CVG
2 stops22h 10m
Multiple Airlines
Fri 8/146:30 am
CVG
-
CLT
1 stop14h 43m
Multiple Airlines
Deal found 6/30$238

Find flight deals from South Carolina to Indiana

Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated July 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$210
(Expedia)

One-way from

$84
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$373

Good round-trip deal

$99 or less

Good one-way deal

$69 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
From South Carolina to Indiana
One-way flight from South Carolina to Indiana
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in July 2026
Price to beat on a round-trip flight from South Carolina to Indiana.
Price to beat on a one-way flight from South Carolina to Indiana.

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteCincinnati

CLT - CVG

CLTCVG

Charlotte Douglas

Tue 8/11

12:24 pm-11:42 pm

1 stop11h 18m

Cincinnati Cinci./N. Kentucky

Sun 8/16

7:15 am-12:22 pm

1 stop5h 07m

$233

SavannahChicago

SAV - ORD

SAVORD

Savannah/Hilton Head

Wed 10/21

4:00 pm-5:34 pm

Nonstop2h 34m

Chicago O'Hare Intl

Sat 10/24

8:50 am-2:38 pm

1 stop4h 48m

$247

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Tue 12/1

6:00 am-10:33 am

1 stop5h 33m

Chicago O'Hare Intl

Sat 12/5

1:15 pm-8:18 pm

1 stop6h 03m

$267

CharlotteChicago

CLT - ORD

CLTORD

Charlotte Douglas

Sat 9/5

11:50 am-4:51 pm

1 stop6h 01m

Chicago O'Hare Intl

Tue 9/8

7:05 am-12:15 pm

1 stop4h 10m

$267

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Thu 8/13

6:34 pm-8:04 pm

Nonstop2h 30m

Chicago O'Hare Intl

Sun 8/16

8:00 am-11:00 am

Nonstop2h 00m

$269

ColumbiaChicago

CAE - ORD

CAEORD

Columbia Metropolitan

Fri 8/21

6:25 am-7:55 am

Nonstop2h 30m

Chicago O'Hare Intl

Sat 8/22

1:55 pm-5:03 pm

Nonstop2h 08m

$269

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Sat 8/29

5:43 pm-7:03 pm

Nonstop2h 20m

Chicago O'Hare Intl

Sat 9/5

5:59 pm-9:07 pm

Nonstop2h 08m

$269
Quickest round-trip

GreenvilleChicago

GSP - ORD

GSPORD

Greenville

Fri 7/24

5:43 pm-7:00 pm

Nonstop2h 17m

Chicago O'Hare Intl

Sun 7/26

6:55 am-9:55 am

Nonstop2h 00m

$269

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Sat 8/8

5:15 pm-8:30 pm

1 stop4h 15m

Chicago Midway

Mon 8/10

8:00 am-11:10 am

Nonstop2h 10m

$270

CharlotteChicago

CLT - MDW

CLTMDW

Charlotte Douglas

Wed 8/12

8:30 am-1:30 pm

2 stops6h 00m

Chicago Midway

Sat 8/15

8:05 am-2:25 pm

1 stop5h 20m

$272

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indiana

What is the cheapest month to book a flight from South Carolina to Indiana?

Currently, June is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $49). Flying from South Carolina to Indiana in March is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IN?

Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2026.

One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 34% on airfare.

How much does it cost to fly round-trip from South Carolina to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated July 1, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Overall

7.9

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Libby,Jun 2026

TUS - LAS

One delay in a 2 layover flight=a good trip. The crew was great.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this South Carolina to Indiana flight route?

  • How long is the flight from South Carolina to Indiana?

    Frontier, United Airlines, and Delta can get you from South Carolina to Indiana in just under 2h 34m. Your travel time can differ by up to 8h 44m. The distance from South Carolina to Indiana is about 773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Indiana one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $38. Users have also found prices from $75 and $98 on Southwest and Delta, respectively.

  • Can I find deals for flights from South Carolina to Indiana that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indiana.

  • Can I find deals for business class flights from South Carolina to Indiana?

    Yes. Cheapflights offers flight deals from South Carolina to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indiana?

    Currently, June is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $49). Flying from South Carolina to Indiana in March is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Indiana

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from South Carolina to Indiana

Discover the top 5 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$50Average$154FlexibilityNo cancel feeOn-time88%
DeltaCheapest$183Average$353FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$189Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$190Average$355FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$403FlexibilityNo cancel feeOn-time71%

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