$71+ Cheap flights from South Carolina to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Indiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Indiana
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Cheapest flights from South Carolina to IndianaExplore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from South Carolina to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:23 pm -
1 stop27h 22m
Wed 9/167:11 am -
1 stop8h 04m
Deal found 8/11![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:23 pm -
1 stop27h 22m
Sat 9/127:11 am -
1 stop8h 04m
Deal found 8/11![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:32 pm -
1 stop7h 04m
Mon 9/148:56 pm -
1 stop11h 39m
Deal found 8/7![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:56 am -
1 stop9h 42m
Tue 9/1511:21 am -
1 stop21h 14m
Deal found 8/10![Frontier logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop21h 44m
Tue 9/158:56 pm -
1 stop18h 20m
Deal found 8/11![Frontier logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:23 pm -
1 stop27h 22m
Wed 9/307:11 am -
1 stop8h 04m
Deal found 8/9![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:56 am -
1 stop8h 57m
Wed 9/27:00 pm -
1 stop13h 01m
Deal found 8/10![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop12h 33m
Wed 9/1611:21 am -
1 stop21h 14m
Deal found 8/9![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:32 am -
1 stop10h 04m
Tue 9/298:56 pm -
1 stop18h 20m
Deal found 8/9![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:23 pm -
1 stop27h 22m
Sat 9/267:11 am -
1 stop8h 04m
Deal found 8/12![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
2 stops21h 01m
Tue 9/1511:21 am -
1 stop21h 14m
Deal found 8/11![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:40 pm -
1 stop12h 45m
Wed 9/237:48 pm -
2 stops22h 33m
Deal found 8/7![Frontier logo]()
$196
Best flights from South Carolina to IndianaDiscover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from South Carolina to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:00 pm -
1 stop4h 59m
Sun 9/66:40 am -
1 stop4h 14m
Deal found 8/7![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:34 pm -
Nonstop2h 25m
Sat 9/128:45 am -
1 stop4h 33m
Deal found 8/11![United Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:25 pm -
Nonstop2h 00m
Mon 9/288:00 am -
Nonstop2h 10m
Deal found 8/7![Southwest logo]()
$283
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:17 am -
Nonstop2h 43m
Thu 10/2911:38 am -
Nonstop2h 17m
Deal found 8/11![American Airlines logo]()
$325
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:25 pm -
1 stop4h 34m
Sun 9/66:40 am -
1 stop3h 51m
Deal found 8/7![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
Nonstop2h 31m
Mon 9/286:29 am -
Nonstop2h 17m
Deal found 8/10![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:30 pm -
2 stops9h 15m
Tue 9/156:50 am -
2 stops12h 15m
Deal found 8/10![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am -
1 stop4h 17m
Mon 11/95:09 pm -
1 stop5h 45m
Deal found 8/10![Delta logo]()
$273
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:25 am -
Nonstop2h 30m
Mon 9/76:29 am -
Nonstop2h 14m
Deal found 8/12![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:35 pm -
1 stop7h 40m
Sun 9/208:35 am -
Nonstop2h 10m
Deal found 8/11![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:17 pm -
1 stop4h 42m
Sun 9/69:24 am -
1 stop5h 43m
Deal found 8/7![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:22 am -
Nonstop2h 34m
Thu 10/86:29 am -
Nonstop2h 17m
Deal found 8/9![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:20 pm -
1 stop6h 25m
Mon 9/283:20 pm -
1 stop5h 20m
Deal found 8/7![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:20 am -
Nonstop2h 07m
Mon 9/146:15 pm -
Nonstop2h 03m
Deal found 8/11![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:10 am -
1 stop6h 49m
Fri 9/256:40 am -
1 stop5h 27m
Deal found 8/11![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:31 pm -
1 stop6h 00m
Sun 9/278:59 am -
1 stop5h 37m
Deal found 8/12![American Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:20 pm -
1 stop3h 50m
Sat 10/176:45 am -
1 stop4h 25m
Deal found 8/8![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:46 pm -
Nonstop2h 19m
Sun 10/256:29 am -
Nonstop2h 01m
Deal found 8/10![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:59 pm -
1 stop5h 57m
Sun 9/135:30 am -
1 stop4h 42m
Deal found 8/7![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:55 pm -
1 stop4h 25m
Sun 8/307:35 am -
1 stop4h 05m
Deal found 8/7![Southwest logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:00 am -
Nonstop2h 18m
Sat 9/125:52 pm -
Nonstop2h 15m
Deal found 8/7![United Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:28 am -
1 stop6h 35m
Mon 10/195:27 am -
1 stop4h 16m
Deal found 8/11![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:25 pm -
1 stop7h 00m
Wed 10/141:40 pm -
2 stops5h 20m
Deal found 8/8![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:24 pm -
Nonstop2h 36m
Wed 9/211:27 am -
Nonstop2h 26m
Deal found 8/7![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:53 pm -
1 stop5h 59m
Sun 10/185:27 am -
1 stop4h 16m
Deal found 8/7![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:40 am -
Nonstop2h 05m
Sun 12/1311:10 am -
2 stops6h 40m
Deal found 8/11![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:23 am -
1 stop5h 03m
Sun 10/186:29 am -
Nonstop2h 17m
Deal found 8/7![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:09 pm -
1 stop6h 50m
Sun 9/135:30 am -
1 stop4h 42m
Deal found 8/7![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:40 pm -
2 stops6h 45m
Tue 9/1511:10 am -
2 stops8h 50m
Deal found 8/7![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:50 pm -
1 stop4h 41m
Mon 9/286:03 pm -
Nonstop2h 12m
Deal found 8/7![United Airlines logo]()
$293
Last-minute flights from South Carolina to IndianaDiscover last-minute flight deals from South Carolina to Indiana. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Indiana. Data last updated August 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:56 am -
1 stop9h 42m
Tue 9/1511:21 am -
1 stop21h 14m
Deal found 8/10![Frontier logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:56 am -
1 stop8h 57m
Wed 9/27:00 pm -
1 stop13h 01m
Deal found 8/10![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop21h 44m
Tue 9/158:56 pm -
1 stop18h 20m
Deal found 8/11![Frontier logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop12h 33m
Wed 9/1611:21 am -
1 stop21h 14m
Deal found 8/9![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
2 stops21h 01m
Tue 9/1511:21 am -
1 stop21h 14m
Deal found 8/11![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:23 pm -
1 stop27h 22m
Wed 9/167:11 am -
1 stop8h 04m
Deal found 8/11![Multiple Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:23 pm -
1 stop27h 22m
Sat 9/127:11 am -
1 stop8h 04m
Deal found 8/11![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:32 pm -
1 stop7h 04m
Mon 9/148:56 pm -
1 stop11h 39m
Deal found 8/7![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:32 pm -
1 stop7h 04m
Sun 9/138:56 pm -
1 stop11h 39m
Deal found 8/10![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:32 am -
1 stop10h 04m
Tue 9/298:56 pm -
1 stop18h 20m
Deal found 8/9![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:23 pm -
1 stop27h 22m
Wed 9/307:11 am -
1 stop8h 04m
Deal found 8/9![Multiple Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:23 pm -
1 stop27h 22m
Sat 9/267:11 am -
1 stop8h 04m
Deal found 8/12![Multiple Airlines logo]()
$189
One-way flights from South Carolina to IndianaSearch for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from South Carolina to Indiana. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:37 am -
1 stop28h 53m
Deal found 8/11![Frontier logo]()
$71
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:23 pm -
1 stop27h 22m
Deal found 8/11![Multiple Airlines logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:34 pm -
1 stop20h 16m
Deal found 8/10![Multiple Airlines logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop12h 33m
Deal found 8/10![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:11 pm -
1 stop20h 35m
Deal found 8/11![Frontier logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:50 pm -
1 stop25h 30m
Deal found 8/9![Multiple Airlines logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:40 pm -
1 stop12h 45m
Deal found 8/8![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:40 pm -
1 stop26h 01m
Deal found 8/7![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/89:52 pm -
1 stop21h 44m
Deal found 8/8![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:18 pm -
1 stop26h 02m
Deal found 8/7![Multiple Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:40 pm -
1 stop12h 01m
Deal found 8/11![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:32 am -
1 stop10h 04m
Deal found 8/11![Frontier logo]()
$92
Find flight deals from South Carolina to Indiana
Keep the following information in mind while searching for South Carolina to Indiana flight deals. Data was last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $159 (Kiwi.com) |
One-way from | $71 (Kiwi.com) |
Popular in | August |
Cheapest in | April |
Average price | $546 |
Good round-trip deal | $96 or less |
Good one-way deal | $107 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from South Carolina to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonChicago
CHS Charleston - ORD Chicago O'Hare Intl
CHSORD
Charleston
Sat 9/5
3:00 pm-6:59 pm
1 stop4h 59m
Chicago O'Hare Intl
Sun 9/6
6:40 am-11:54 am
1 stop4h 14m
$257
SavannahChicago
SAV Savannah/Hilton Head - ORD Chicago O'Hare Intl
SAVORD
Savannah/Hilton Head
Sat 9/5
3:25 pm-6:59 pm
1 stop4h 34m
Chicago O'Hare Intl
Sun 9/6
6:40 am-11:31 am
1 stop3h 51m
$257
CharlotteChicago
CLT Charlotte Douglas - MDW Chicago Midway
CLTMDW
Charlotte Douglas
Fri 11/6
6:00 am-9:17 am
1 stop4h 17m
Chicago Midway
Mon 11/9
5:09 pm-11:54 pm
1 stop5h 45m
$273
CharlotteChicago
CLT Charlotte Douglas - ORD Chicago O'Hare Intl
CLTORD
Charlotte Douglas
Wed 9/2
12:34 pm-1:59 pm
Nonstop2h 25m
Chicago O'Hare Intl
Sat 9/12
8:45 am-2:18 pm
1 stop4h 33m
$275
ColumbiaChicago
CAE Columbia Metropolitan - ORD Chicago O'Hare Intl
CAEORD
Columbia Metropolitan
Thu 9/24
6:15 am-7:46 am
Nonstop2h 31m
Chicago O'Hare Intl
Mon 9/28
6:29 am-9:46 am
Nonstop2h 17m
$279
ColumbiaChicago
CAE Columbia Metropolitan - ORD Chicago O'Hare Intl
CAEORD
Columbia Metropolitan
Thu 9/3
6:25 am-7:55 am
Nonstop2h 30m
Chicago O'Hare Intl
Mon 9/7
6:29 am-9:43 am
Nonstop2h 14m
$279
CharlotteChicago
CLT Charlotte Douglas - MDW Chicago Midway
CLTMDW
Charlotte Douglas
Sat 9/5
1:17 pm-4:59 pm
1 stop4h 42m
Chicago Midway
Sun 9/6
9:24 am-4:07 pm
1 stop5h 43m
$279
ColumbiaChicago
CAE Columbia Metropolitan - ORD Chicago O'Hare Intl
CAEORD
Columbia Metropolitan
Thu 10/1
10:22 am-11:56 am
Nonstop2h 34m
Chicago O'Hare Intl
Thu 10/8
6:29 am-9:46 am
Nonstop2h 17m
$279
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Thu 9/10
6:20 am-7:27 am
Nonstop2h 07m
Chicago O'Hare Intl
Mon 9/14
6:15 pm-9:18 pm
Nonstop2h 03m
$279
GreenvilleChicago
GSP Greenville - ORD Chicago O'Hare Intl
GSPORD
Greenville
Fri 10/23
5:46 pm-7:05 pm
Nonstop2h 19m
Chicago O'Hare Intl
Sun 10/25
6:29 am-9:30 am
Nonstop2h 01m
$279
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from South Carolina with our price prediction graph.
SAV-ORD
CLT-CVG
CLT-IND
CHS-ORD
CLT-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Indiana
USSC-USIN
SAV-ORD
CLT-CVG
CLT-IND
CHS-ORD
What is the cheapest month to book a flight from South Carolina to Indiana?
Currently, March is the cheapest month in which you can book a flight from South Carolina to Indiana (average of $306). Flying from South Carolina to Indiana in April is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to IN?
Find hourly flight availability from South Carolina to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 12, 2026.
One of the essential ways to save on airfare from South Carolina to Indiana is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 42% on airfare.
How much does it cost to fly round-trip from South Carolina to Indiana?
Airfare is below average for this route at the moment.
South Carolina to Indiana flights typically cost between $345 and $561 in September.The cheapest round-trip price found within the last 5 days was $166 on Multiple Airlines (Sep 1-Sep 8).
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated August 12, 2026.
Read through reviews of airlines operating flights from South Carolina to Indiana, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Indiana by cabin class
Find flights from South Carolina to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Indiana flights
Browse other South Carolina and Indiana flight options. Last updated on August 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Indiana
Find the right flight back to South Carolina after your stay in Indiana
South Carolina to Indiana flights
Consider these flights traveling from South Carolina to Indiana.
Top 5 airlines flying from South Carolina to Indiana
Discover the top 5 airlines that operate flights from South Carolina to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$76 | Average$151 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$183 | Average$343 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$189 | Average$381 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$190 | Average$349 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$403 | FlexibilityNo cancel fee | On-time71% |