$63+ Cheap flights from Louisville to Myrtle Beach (SDF - MYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — MYR
Aug 14 — Aug 211
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Myrtle Beach
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Cheapest flights from Louisville to Myrtle BeachExplore the most affordable flight options available from Louisville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
Explore the most affordable flight options available from Louisville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$63
This Super.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:21 am
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/810:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/13![Allegiant Air logo]()
$78
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/18:57 am
MYR
- SDF
Nonstop1h 34m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/2510:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$95
Best flights from Louisville to Myrtle BeachDiscover carefully curated flight deals from Louisville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
Discover carefully curated flight deals from Louisville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:17 am
SDF
- MYR
1 stop3h 53m
Delta
Sat 9/56:00 am
MYR
- SDF
1 stop4h 32m
Delta
Deal found 7/11![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/103:35 pm
SDF
- MYR
1 stop3h 55m
Southwest
Sat 10/171:10 pm
MYR
- SDF
1 stop6h 45m
Southwest
Deal found 7/12![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 pm
SDF
- MYR
1 stop3h 42m
Delta
Mon 9/286:59 pm
MYR
- SDF
1 stop5h 00m
Delta
Deal found 7/15![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:15 pm
SDF
- MYR
2 stops6h 05m
Southwest
Tue 8/182:25 pm
MYR
- SDF
1 stop7h 05m
Southwest
Deal found 7/14![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
SDF
- MYR
1 stop4h 47m
Delta
Wed 9/24:10 pm
MYR
- SDF
1 stop5h 58m
Delta
Deal found 7/11![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:45 am
SDF
- MYR
2 stops8h 55m
Southwest
Sat 9/55:00 pm
MYR
- SDF
1 stop4h 20m
Southwest
Deal found 7/14![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:05 am
SDF
- MYR
1 stop3h 42m
Delta
Wed 8/196:00 am
MYR
- SDF
1 stop4h 32m
Delta
Deal found 7/15![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:15 pm
SDF
- MYR
1 stop4h 25m
Southwest
Fri 8/212:30 pm
MYR
- SDF
1 stop6h 00m
Southwest
Deal found 7/15![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:05 am
SDF
- MYR
1 stop3h 42m
Delta
Sun 9/66:00 am
MYR
- SDF
1 stop4h 32m
Delta
Deal found 7/11![Delta logo]()
$310
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:45 am
SDF
- MYR
2 stops10h 25m
Southwest
Sat 9/261:40 pm
MYR
- SDF
2 stops7h 40m
Southwest
Deal found 7/15![Southwest logo]()
$316
Last-minute flights from Louisville to Myrtle BeachDiscover last-minute flight deals from Louisville to Myrtle Beach. Data last updated July 15, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Myrtle Beach. Data last updated July 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 7/2510:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Deal found 7/12![Allegiant Air logo]()
$95
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/18:57 am
MYR
- SDF
Nonstop1h 34m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$82
This Super.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:21 am
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Sat 8/810:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/13![Allegiant Air logo]()
$78
This Booking.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:11 pm
SDF
- MYR
Nonstop1h 32m
Allegiant Air
Sat 8/1510:39 am
MYR
- SDF
Nonstop1h 42m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$63
One-way flights from Louisville to Myrtle BeachSearch for one-way flight options from Louisville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
Search for one-way flight options from Louisville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:25 am
SDF
- MYR
1 stop10h 57m
Breeze Airways
Deal found 7/14![Breeze Airways logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:55 pm
SDF
- MYR
1 stop20h 11m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:25 am
SDF
- MYR
1 stop10h 57m
Breeze Airways
Deal found 7/14![Breeze Airways logo]()
$135
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:10 am
SDF
- MYR
1 stop6h 24m
American Airlines
Deal found 7/15![American Airlines logo]()
$137
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:15 pm
SDF
- MYR
2 stops6h 05m
Southwest
Deal found 7/15![Southwest logo]()
$142
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:20 pm
SDF
- MYR
1 stop4h 00m
Southwest
Deal found 7/15![Southwest logo]()
$145
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 am
SDF
- MYR
2 stops10h 35m
Southwest
Deal found 7/15![Southwest logo]()
$150
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:30 am
SDF
- MYR
1 stop5h 20m
Southwest
Deal found 7/11![Southwest logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:24 pm
SDF
- MYR
2 stops23h 26m
Allegiant Air
Deal found 7/11![Allegiant Air logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:12 am
SDF
- MYR
2 stops22h 38m
Breeze Airways
Deal found 7/15![Breeze Airways logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:25 am
SDF
- MYR
2 stops22h 43m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$194
Find flight deals from Louisville to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $63 (Booking.com) |
Popular in | January |
Cheapest in | June |
Average price | $320 |
Good round-trip deal | $80 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
Use the filters below to find and compare flights from Louisville to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 9/1
11:17 am-3:10 pm
1 stop3h 53m
Myrtle Beach Intl
Sat 9/5
6:00 am-10:32 am
1 stop4h 32m
$273
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Sat 9/26
6:00 pm-9:42 pm
1 stop3h 42m
Myrtle Beach Intl
Mon 9/28
6:59 pm-11:59 pm
1 stop5h 00m
$273
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 9/1
6:00 am-10:47 am
1 stop4h 47m
Myrtle Beach Intl
Wed 9/2
4:10 pm-10:08 pm
1 stop5h 58m
$273
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Sat 10/10
3:35 pm-7:30 pm
1 stop3h 55m
Myrtle Beach Intl
Sat 10/17
1:10 pm-7:55 pm
1 stop6h 45m
$281
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 8/11
1:15 pm-7:20 pm
2 stops6h 05m
Myrtle Beach Intl
Tue 8/18
2:25 pm-9:30 pm
1 stop7h 05m
$286
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Sat 8/29
6:45 am-3:40 pm
2 stops8h 55m
Myrtle Beach Intl
Sat 9/5
5:00 pm-9:20 pm
1 stop4h 20m
$286
Quickest round-trip
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Fri 8/14
7:05 am-10:47 am
1 stop3h 42m
Myrtle Beach Intl
Wed 8/19
6:00 am-10:32 am
1 stop4h 32m
$310
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 8/18
1:15 pm-5:40 pm
1 stop4h 25m
Myrtle Beach Intl
Fri 8/21
2:30 pm-8:30 pm
1 stop6h 00m
$310
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Mon 8/31
7:05 am-10:47 am
1 stop3h 42m
Myrtle Beach Intl
Sun 9/6
6:00 am-10:32 am
1 stop4h 32m
$310
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 9/22
8:45 am-7:10 pm
2 stops10h 25m
Myrtle Beach Intl
Sat 9/26
1:40 pm-9:20 pm
2 stops7h 40m
$316
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Louisville to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Myrtle Beach in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Louisville with our price prediction graph.
SDF-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Myrtle Beach
How far ahead should I book a flight from Louisville to Myrtle Beach?
The price you pay for your flight from Louisville to Myrtle Beach may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Louisville to Myrtle Beach?
Currently, June is the cheapest month in which you can book a flight from Louisville to Myrtle Beach (average of $274). Flying from Louisville to Myrtle Beach in January is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to MYR?
Find hourly flight availability from Louisville to Myrtle Beach. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 15, 2026.
It’s typically best to fly out from Louisville to Myrtle Beach in the evening. Doing so could potentially save you 34% on the flight price compared to flying in the morning, which is usually more expensive.
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated July 15, 2026.
Read through reviews of airlines operating flights from Louisville to Myrtle Beach, such as Southwest,Delta, andAllegiant Air. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Louisville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Little River
Garden City Beach
Surfside Beach
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Complete your trip to Myrtle Beach by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 15, 2026.
Louisville and Myrtle Beach flights
Browse other Louisville and Myrtle Beach flight options. Last updated on July 15, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on July 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Louisville to Myrtle Beach
Discover the top 4 airlines that operate flights from Louisville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$144 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$196 | Average$327 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$241 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$318 | Average$386 | FlexibilityNo cancel fee | On-time63% |