$114+ Cheap flights from Knoxville to Charleston (TYS - CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CHS
Sep 12 — Sep 191
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Charleston
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Cheapest flights from Knoxville to CharlestonExplore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
Explore the most affordable flight options available from Knoxville to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:24 pm -
1 stop3h 27m
Fri 10/305:30 am -
1 stop5h 24m
Deal found 8/12![Delta logo]()
$230
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop4h 28m
Wed 9/166:40 am -
1 stop2h 49m
Deal found 8/10![Delta logo]()
$241
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
1 stop4h 51m
Tue 9/86:26 pm -
1 stop4h 01m
Deal found 8/10![Delta logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:21 pm -
1 stop27h 35m
Mon 9/143:27 pm -
1 stop5h 12m
Deal found 8/8![Multiple Airlines logo]()
$251
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:40 am -
1 stop4h 28m
Sun 9/66:00 am -
1 stop3h 44m
Deal found 8/12![Delta logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:15 am -
1 stop9h 48m
Mon 10/194:57 pm -
1 stop25h 17m
Deal found 8/9![Multiple Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:18 pm -
1 stop3h 47m
Sun 9/138:41 pm -
1 stop3h 10m
Deal found 8/10![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am -
1 stop5h 54m
Sun 9/66:41 pm -
1 stop3h 58m
Deal found 8/9![Delta logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:00 am -
1 stop25h 38m
Fri 10/308:58 pm -
2 stops13h 07m
Deal found 8/12![Multiple Airlines logo]()
$299
Best flights from Knoxville to CharlestonDiscover carefully curated flight deals from Knoxville to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
Discover carefully curated flight deals from Knoxville to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:23 pm -
1 stop4h 28m
Fri 10/306:30 am -
1 stop4h 24m
Deal found 8/12![Delta logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:21 pm -
1 stop27h 35m
Mon 9/143:27 pm -
1 stop5h 12m
Deal found 8/8![Multiple Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:04 pm -
1 stop3h 53m
Sun 12/68:32 pm -
1 stop3h 26m
Deal found 8/12![American Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:05 am -
1 stop4h 30m
Sat 10/38:05 am -
2 stops9h 45m
Deal found 8/9![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
1 stop4h 51m
Tue 9/86:26 pm -
1 stop4h 01m
Deal found 8/10![Delta logo]()
$242
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:40 am -
1 stop4h 28m
Sun 9/66:00 am -
1 stop3h 44m
Deal found 8/12![Delta logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:25 pm -
2 stops19h 25m
Mon 10/194:57 pm -
1 stop25h 17m
Deal found 8/9![Multiple Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:25 pm -
2 stops14h 45m
Fri 10/306:35 am -
2 stops14h 55m
Deal found 8/12![Southwest logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am -
1 stop9h 48m
Sun 10/410:05 pm -
1 stop21h 19m
Deal found 8/8![Multiple Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/155:57 pm -
1 stop3h 49m
Sun 1/175:30 am -
1 stop3h 42m
Deal found 8/11![Delta logo]()
$347
Last-minute flights from Knoxville to CharlestonDiscover last-minute flight deals from Knoxville to Charleston. Data last updated August 13, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Charleston. Data last updated August 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm -
1 stop17h 57m
Sun 8/237:47 pm -
1 stop22h 17m
Deal found 8/9![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:52 pm -
2 stops29h 14m
Mon 8/312:16 pm -
1 stop4h 47m
Deal found 8/12![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:22 pm -
1 stop4h 42m
Sat 9/59:13 am -
1 stop6h 00m
Deal found 8/9![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:40 am -
1 stop4h 28m
Sun 9/66:00 am -
1 stop3h 44m
Deal found 8/12![Delta logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:33 pm -
1 stop17h 55m
Tue 9/811:15 am -
1 stop22h 49m
Deal found 8/10![Multiple Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 pm -
1 stop4h 51m
Tue 9/86:26 pm -
1 stop4h 01m
Deal found 8/10![Delta logo]()
$242
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am -
1 stop5h 54m
Sun 9/66:41 pm -
1 stop3h 58m
Deal found 8/9![Delta logo]()
$296
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop4h 28m
Wed 9/166:40 am -
1 stop2h 49m
Deal found 8/10![Delta logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:21 pm -
1 stop27h 35m
Mon 9/143:27 pm -
1 stop5h 12m
Deal found 8/8![Multiple Airlines logo]()
$251
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:18 pm -
1 stop3h 47m
Sun 9/138:41 pm -
1 stop3h 10m
Deal found 8/10![American Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:25 pm -
1 stop3h 46m
Sun 9/275:25 am -
1 stop4h 04m
Deal found 8/12![Delta logo]()
$317
One-way flights from Knoxville to CharlestonSearch for one-way flight options from Knoxville to Charleston. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
Search for one-way flight options from Knoxville to Charleston. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:55 am -
1 stop4h 50m
Deal found 8/10![Southwest logo]()
$114
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop4h 13m
Deal found 8/10![Delta logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3012:55 pm -
3 stops44h 42m
Deal found 8/8![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:50 pm -
2 stops31h 44m
Deal found 8/10![Multiple Airlines logo]()
$163
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:25 pm -
1 stop3h 35m
Deal found 8/9![American Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:01 pm -
2 stops20h 02m
Deal found 8/10![Multiple Airlines logo]()
$178
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:41 pm -
1 stop4h 18m
Deal found 8/8![Delta logo]()
$194
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:25 am -
2 stops12h 25m
Deal found 8/11![Southwest logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:56 pm -
1 stop18h 08m
Deal found 8/12![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:39 pm -
3 stops58h 59m
Deal found 8/11![Multiple Airlines logo]()
$259
Find flight deals from Knoxville to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $230 (Delta) |
One-way from | $114 (Southwest) |
Popular in | May |
Cheapest in | August |
Average price | $348 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Knoxville to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Mon 10/26
6:23 pm-10:51 pm
1 stop4h 28m
Charleston
Fri 10/30
6:30 am-10:54 am
1 stop4h 24m
$230
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Sat 9/5
5:00 pm-9:51 pm
1 stop4h 51m
Charleston
Tue 9/8
6:26 pm-10:27 pm
1 stop4h 01m
$242
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Thu 9/10
5:21 pm-8:56 pm
1 stop27h 35m
Charleston
Mon 9/14
3:27 pm-8:39 pm
1 stop5h 12m
$251
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Thu 9/3
5:40 am-10:08 am
1 stop4h 28m
Charleston
Sun 9/6
6:00 am-9:44 am
1 stop3h 44m
$260
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Thu 10/15
6:25 pm-1:50 pm
2 stops19h 25m
Charleston
Mon 10/19
4:57 pm-6:14 pm
1 stop25h 17m
$324
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Thu 10/1
6:15 am-4:03 pm
1 stop9h 48m
Charleston
Sun 10/4
10:05 pm-7:24 pm
1 stop21h 19m
$337
Quickest round-trip
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Fri 12/4
8:04 pm-11:57 pm
1 stop3h 53m
Charleston
Sun 12/6
8:32 pm-11:58 pm
1 stop3h 26m
$347
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Fri 1/15
5:57 pm-9:46 pm
1 stop3h 49m
Charleston
Sun 1/17
5:30 am-9:12 am
1 stop3h 42m
$347
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Wed 9/30
8:05 am-12:35 pm
1 stop4h 30m
Charleston
Sat 10/3
8:05 am-5:50 pm
2 stops9h 45m
$368
KnoxvilleCharleston
TYS Knoxville McGhee Tyson - CHS Charleston
TYSCHS
Knoxville McGhee Tyson
Mon 10/26
7:25 pm-10:10 am
2 stops14h 45m
Charleston
Fri 10/30
6:35 am-9:30 pm
2 stops14h 55m
$369
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Charleston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Charleston in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Knoxville with our price prediction graph.
TYS-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated August 13, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Knoxville to Charleston to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Overall
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Knoxville to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Charleston flights
Browse other Knoxville and Charleston flight options. Last updated on August 13, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on August 13, 2026.
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Top 2 airlines flying from Knoxville to Charleston
Discover the top 2 airlines that operate flights from Knoxville to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$527 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$412 | FlexibilityNo cancel fee | On-timeN/A |