$293+ Cheap flights from Knoxville to Columbia (TYS - CAE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CAE
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Columbia
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Cheapest flights from Knoxville to ColumbiaExplore the most affordable flight options available from Knoxville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Knoxville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:38 pm -
1 stop5h 38m
Sun 12/68:17 pm -
1 stop3h 42m
Deal found 10/22![American Airlines logo]()
$417
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:40 am -
1 stop3h 41m
Mon 11/231:59 pm -
1 stop6h 10m
Deal found 10/24![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 am -
1 stop3h 41m
Sun 11/157:55 pm -
1 stop4h 04m
Deal found 10/25![Delta logo]()
$467
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop5h 08m
Fri 11/131:59 pm -
1 stop3h 23m
Deal found 10/22![Delta logo]()
$487
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:49 am -
1 stop3h 28m
Mon 11/96:20 am -
1 stop3h 25m
Deal found 10/21![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop3h 50m
Wed 11/117:00 am -
1 stop2h 55m
Deal found 10/22![Delta logo]()
$517
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:18 am -
1 stop4h 07m
Tue 12/298:50 am -
1 stop6h 30m
Deal found 10/23![American Airlines logo]()
$530
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:38 pm -
1 stop5h 32m
Sun 10/257:19 pm -
1 stop4h 40m
Deal found 10/21![Delta logo]()
$572
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops12h 06m
Thu 11/128:32 pm -
1 stop3h 26m
Deal found 10/22![American Airlines logo]()
$606
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:45 pm -
1 stop4h 02m
Mon 11/27:00 am -
1 stop3h 45m
Deal found 10/24![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:40 am -
1 stop5h 03m
Sun 10/255:59 pm -
1 stop6h 00m
Deal found 10/21![Delta logo]()
$627
Best flights from Knoxville to ColumbiaDiscover carefully curated flight deals from Knoxville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Knoxville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:00 pm -
1 stop5h 41m
Fri 11/272:07 pm -
1 stop6h 02m
Deal found 10/21![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:49 am -
1 stop3h 28m
Mon 11/96:20 am -
1 stop3h 25m
Deal found 10/21![American Airlines logo]()
$497
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/69:45 am -
1 stop9h 39m
Wed 2/109:45 am -
1 stop14h 14m
Deal found 10/22![United Airlines logo]()
$683
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 am -
1 stop4h 08m
Sat 11/2810:05 am -
1 stop3h 50m
Deal found 10/23![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop3h 50m
Wed 11/117:00 am -
1 stop2h 55m
Deal found 10/22![Delta logo]()
$517
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:45 am -
1 stop24h 14m
Wed 11/117:54 pm -
1 stop15h 36m
Deal found 10/23![United Airlines logo]()
$723
Last-minute flights from Knoxville to ColumbiaDiscover last-minute flight deals from Knoxville to Columbia. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Columbia. Data last updated October 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:40 am -
1 stop5h 03m
Sun 10/255:59 pm -
1 stop6h 00m
Deal found 10/21![Delta logo]()
$627
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:38 pm -
1 stop5h 32m
Sun 10/257:19 pm -
1 stop4h 40m
Deal found 10/21![Delta logo]()
$572
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:45 pm -
1 stop4h 02m
Mon 11/27:00 am -
1 stop3h 45m
Deal found 10/24![Delta logo]()
$622
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop5h 08m
Fri 11/131:59 pm -
1 stop3h 23m
Deal found 10/22![Delta logo]()
$487
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:49 am -
1 stop3h 28m
Mon 11/96:20 am -
1 stop3h 25m
Deal found 10/21![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:40 am -
1 stop3h 50m
Wed 11/117:00 am -
1 stop2h 55m
Deal found 10/22![Delta logo]()
$517
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops12h 06m
Thu 11/128:32 pm -
1 stop3h 26m
Deal found 10/22![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:04 pm -
1 stop3h 49m
Tue 11/105:21 pm -
1 stop5h 27m
Deal found 10/22![American Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:01 am -
1 stop6h 12m
Fri 11/134:11 pm -
1 stop5h 30m
Deal found 10/25![American Airlines logo]()
$685
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:40 am -
1 stop3h 41m
Sun 11/157:55 pm -
1 stop4h 04m
Deal found 10/25![Delta logo]()
$467
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:40 am -
1 stop3h 41m
Mon 11/231:59 pm -
1 stop6h 10m
Deal found 10/24![Delta logo]()
$427
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:00 pm -
1 stop5h 41m
Fri 11/272:07 pm -
1 stop6h 02m
Deal found 10/21![Delta logo]()
$417
One-way flights from Knoxville to ColumbiaSearch for one-way flight options from Knoxville to Columbia. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Knoxville to Columbia. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:01 pm -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:40 am -
1 stop3h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Delta logo]()
$423
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:55 pm -
1 stop20h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$454
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:07 pm -
2 stops27h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$598
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:45 am -
2 stops12h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$653
Find flight deals from Knoxville to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $417 (American Airlines) |
One-way from | $293 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Fri 11/20
4:00 pm-9:41 pm
1 stop5h 41m
Columbia Metropolitan
Fri 11/27
2:07 pm-8:09 pm
1 stop6h 02m
$417
Quickest round-trip
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Mon 11/2
5:40 am-9:30 am
1 stop3h 50m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$423
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Sat 11/21
7:00 am-11:08 am
1 stop4h 08m
Columbia Metropolitan
Sat 11/28
10:05 am-1:55 pm
1 stop3h 50m
$427
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Thu 11/5
8:49 am-12:17 pm
1 stop3h 28m
Columbia Metropolitan
Mon 11/9
6:20 am-9:45 am
1 stop3h 25m
$497
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Thu 11/5
5:40 am-9:30 am
1 stop3h 50m
Columbia Metropolitan
Wed 11/11
7:00 am-9:55 am
1 stop2h 55m
$517
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Tue 12/1
2:07 pm-5:09 pm
2 stops27h 02m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$598
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Mon 11/2
6:45 am-7:08 pm
2 stops12h 23m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$653
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Sat 2/6
9:45 am-7:24 pm
1 stop9h 39m
Columbia Metropolitan
Wed 2/10
9:45 am-11:59 pm
1 stop14h 14m
$683
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Sat 11/7
9:45 am-9:59 am
1 stop24h 14m
Columbia Metropolitan
Wed 11/11
7:54 pm-11:30 am
1 stop15h 36m
$723
Sorted by cheapest first
Compare providers for flights from Knoxville to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Columbia in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Columbia flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Knoxville with our price prediction graph.
TYS-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsIrmo
Orangeburg
West Columbia
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