$272+ Cheap flights from Knoxville to Columbia (TYS - CAE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CAE
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Columbia
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Cheapest flights from Knoxville to ColumbiaExplore the most affordable flight options available from Knoxville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Knoxville to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:23 pm -
1 stop5h 24m
Sat 10/318:00 am -
1 stop5h 31m
Deal found 9/9![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop3h 00m
Sun 10/257:19 pm -
1 stop4h 40m
Deal found 9/6![Delta logo]()
$407
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 pm -
1 stop4h 24m
Mon 9/281:59 pm -
1 stop4h 41m
Deal found 9/9![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:18 pm -
1 stop3h 47m
Sat 9/267:33 pm -
1 stop3h 17m
Deal found 9/6![American Airlines logo]()
$536
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am -
1 stop3h 45m
Thu 10/15:59 pm -
1 stop5h 56m
Deal found 9/8![Delta logo]()
$542
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 am -
1 stop5h 32m
Sat 9/267:30 am -
1 stop5h 28m
Deal found 9/7![Delta logo]()
$584
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:58 pm -
1 stop3h 58m
Sun 10/2511:03 am -
1 stop5h 15m
Deal found 9/8![American Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:06 pm -
1 stop4h 59m
Thu 10/16:25 am -
1 stop3h 19m
Deal found 9/8![American Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:13 pm -
1 stop5h 36m
Thu 9/245:40 am -
1 stop3h 49m
Deal found 9/9![Delta logo]()
$725
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 am -
1 stop8h 41m
Mon 9/2810:23 am -
1 stop9h 56m
Deal found 9/9![United Airlines logo]()
$747
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:20 pm -
1 stop19h 01m
Sat 9/2610:23 am -
1 stop24h 14m
Deal found 9/6![United Airlines logo]()
$756
Best flights from Knoxville to ColumbiaDiscover carefully curated flight deals from Knoxville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Knoxville to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop3h 00m
Sun 10/257:00 am -
1 stop3h 54m
Deal found 9/5![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:35 pm -
1 stop18h 41m
Wed 2/102:40 pm -
1 stop9h 25m
Deal found 9/9![United Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 am -
1 stop5h 32m
Sat 9/267:30 am -
1 stop5h 28m
Deal found 9/7![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:13 pm -
1 stop5h 36m
Thu 9/245:40 am -
1 stop3h 49m
Deal found 9/9![Delta logo]()
$725
Last-minute flights from Knoxville to ColumbiaDiscover last-minute flight deals from Knoxville to Columbia. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Columbia. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am -
1 stop3h 45m
Thu 10/15:59 pm -
1 stop5h 56m
Deal found 9/8![Delta logo]()
$542
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:06 pm -
1 stop4h 59m
Thu 10/16:25 am -
1 stop3h 19m
Deal found 9/8![American Airlines logo]()
$638
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:13 pm -
1 stop5h 36m
Thu 9/245:40 am -
1 stop3h 49m
Deal found 9/9![Delta logo]()
$725
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:18 pm -
1 stop3h 47m
Sat 9/267:33 pm -
1 stop3h 17m
Deal found 9/6![American Airlines logo]()
$536
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 am -
1 stop5h 32m
Sat 9/267:30 am -
1 stop5h 28m
Deal found 9/7![Delta logo]()
$584
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:20 pm -
1 stop19h 01m
Sat 9/2610:23 am -
1 stop24h 14m
Deal found 9/6![United Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:25 pm -
1 stop4h 24m
Mon 9/281:59 pm -
1 stop4h 41m
Deal found 9/9![Delta logo]()
$457
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:45 am -
1 stop8h 41m
Mon 9/2810:23 am -
1 stop9h 56m
Deal found 9/9![United Airlines logo]()
$747
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:23 pm -
1 stop3h 00m
Sun 10/257:19 pm -
1 stop4h 40m
Deal found 9/6![Delta logo]()
$407
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:58 pm -
1 stop3h 58m
Sun 10/2511:03 am -
1 stop5h 15m
Deal found 9/8![American Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:23 pm -
1 stop5h 24m
Sat 10/318:00 am -
1 stop5h 31m
Deal found 9/9![Delta logo]()
$377
One-way flights from Knoxville to ColumbiaSearch for one-way flight options from Knoxville to Columbia. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Knoxville to Columbia. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:56 am -
1 stop3h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:26 am -
1 stop2h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:06 pm -
1 stop4h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:40 am -
1 stop3h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:20 pm -
2 stops25h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:45 am -
2 stops11h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:35 pm -
2 stops21h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![United Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:02 pm -
2 stops25h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$716
Find flight deals from Knoxville to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbia (CAE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $377 (Delta) |
One-way from | $272 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Knoxville to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Wed 10/21
6:56 am-10:33 am
1 stop3h 37m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$272
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Fri 10/23
6:23 pm-9:23 pm
1 stop3h 00m
Columbia Metropolitan
Sun 10/25
7:00 am-10:54 am
1 stop3h 54m
$407
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Fri 9/18
5:40 am-9:25 am
1 stop3h 45m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$413
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Fri 9/18
7:20 pm-9:13 pm
2 stops25h 53m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$485
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Wed 10/21
5:45 am-4:57 pm
2 stops11h 12m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$527
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Tue 9/22
5:40 am-11:12 am
1 stop5h 32m
Columbia Metropolitan
Sat 9/26
7:30 am-12:58 pm
1 stop5h 28m
$584
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Sat 2/6
7:35 pm-2:16 pm
1 stop18h 41m
Columbia Metropolitan
Wed 2/10
2:40 pm-12:05 am
1 stop9h 25m
$601
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Mon 9/28
1:35 pm-11:15 am
2 stops21h 40m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$613
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Thu 9/17
6:02 pm-7:07 pm
2 stops25h 05m
Columbia Metropolitan
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$716
KnoxvilleColumbia
TYS Knoxville McGhee Tyson - CAE Columbia Metropolitan
TYSCAE
Knoxville McGhee Tyson
Mon 9/21
6:13 pm-11:49 pm
1 stop5h 36m
Columbia Metropolitan
Thu 9/24
5:40 am-9:29 am
1 stop3h 49m
$725
Sorted by cheapest first
Compare providers for flights from Knoxville to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Columbia flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Columbia flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Columbia flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Columbia flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Columbia flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Knoxville with our price prediction graph.
TYS-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsIrmo
West Columbia
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