$293+ Cheap flights from Columbia to Knoxville (CAE - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
CAE — TYS
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Columbia to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Knoxville
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Cheapest flights from Columbia to KnoxvilleExplore the most affordable flight options available from Columbia to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Columbia to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:21 pm -
1 stop3h 32m
Thu 12/313:06 pm -
1 stop4h 45m
Deal found 10/25![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:12 pm -
1 stop3h 36m
Wed 11/1112:20 pm -
1 stop4h 35m
Deal found 10/23![American Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:00 pm -
1 stop4h 47m
Sun 10/259:12 am -
1 stop5h 56m
Deal found 10/22![Delta logo]()
$592
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
1 stop4h 28m
Fri 11/135:40 am -
1 stop3h 41m
Deal found 10/24![Delta logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:52 pm -
1 stop20h 38m
Sat 11/149:45 am -
1 stop24h 14m
Deal found 10/25![United Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:54 pm -
2 stops17h 19m
Wed 11/117:35 pm -
1 stop18h 42m
Deal found 10/23![United Airlines logo]()
$803
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:37 pm -
2 stops30h 22m
Fri 11/131:55 pm -
1 stop20h 04m
Deal found 10/24![United Airlines logo]()
$817
Best flights from Columbia to KnoxvilleDiscover carefully curated flight deals from Columbia to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Columbia to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:00 am -
1 stop3h 12m
Mon 1/185:30 am -
1 stop5h 42m
Deal found 10/22![Delta logo]()
$437
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:12 pm -
1 stop3h 36m
Wed 11/1112:20 pm -
1 stop4h 35m
Deal found 10/23![American Airlines logo]()
$497
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:37 am -
2 stops13h 22m
Sat 11/149:45 am -
1 stop24h 14m
Deal found 10/25![United Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
1 stop4h 28m
Fri 11/135:40 am -
1 stop3h 41m
Deal found 10/24![Delta logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:54 pm -
2 stops17h 19m
Wed 11/117:35 pm -
1 stop18h 42m
Deal found 10/23![United Airlines logo]()
$803
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2610:47 am -
2 stops8h 44m
Thu 12/319:26 am -
2 stops11h 07m
Deal found 10/25![American Airlines logo]()
$852
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/1610:05 am -
3 stops25h 40m
Mon 1/187:10 pm -
2 stops16h 38m
Deal found 10/22![United Airlines logo]()
$809
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:37 pm -
2 stops30h 22m
Fri 11/131:55 pm -
1 stop20h 04m
Deal found 10/24![United Airlines logo]()
$817
Last-minute flights from Columbia to KnoxvilleDiscover last-minute flight deals from Columbia to Knoxville. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to Knoxville. Data last updated October 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:00 pm -
1 stop4h 47m
Sun 10/259:12 am -
1 stop5h 56m
Deal found 10/22![Delta logo]()
$592
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
2 stops13h 30m
Sun 10/259:45 am -
1 stop24h 14m
Deal found 10/22![United Airlines logo]()
$1,050
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:12 pm -
1 stop3h 36m
Wed 11/1112:20 pm -
1 stop4h 35m
Deal found 10/23![American Airlines logo]()
$497
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:54 pm -
2 stops17h 19m
Wed 11/117:35 pm -
1 stop18h 42m
Deal found 10/23![United Airlines logo]()
$803
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
1 stop4h 28m
Fri 11/135:40 am -
1 stop3h 41m
Deal found 10/24![Delta logo]()
$685
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:37 pm -
2 stops30h 22m
Fri 11/131:55 pm -
1 stop20h 04m
Deal found 10/24![United Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:52 pm -
1 stop20h 38m
Sat 11/149:45 am -
1 stop24h 14m
Deal found 10/25![United Airlines logo]()
$742
One-way flights from Columbia to KnoxvilleSearch for one-way flight options from Columbia to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Columbia to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 am -
1 stop3h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:54 pm -
2 stops21h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$566
Find flight deals from Columbia to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Columbia (CAE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $437 (Delta) |
One-way from | $293 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Columbia to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Tue 11/24
5:00 am-8:49 am
1 stop3h 49m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Sat 1/16
6:00 am-9:12 am
1 stop3h 12m
Knoxville McGhee Tyson
Mon 1/18
5:30 am-11:12 am
1 stop5h 42m
$437
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Sat 11/7
7:12 pm-10:48 pm
1 stop3h 36m
Knoxville McGhee Tyson
Wed 11/11
12:20 pm-4:55 pm
1 stop4h 35m
$497
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Tue 11/24
7:54 pm-4:59 pm
2 stops21h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$566
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Mon 11/9
7:00 am-11:28 am
1 stop4h 28m
Knoxville McGhee Tyson
Fri 11/13
5:40 am-9:21 am
1 stop3h 41m
$685
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Tue 11/10
10:37 am-11:59 pm
2 stops13h 22m
Knoxville McGhee Tyson
Sat 11/14
9:45 am-9:59 am
1 stop24h 14m
$777
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Sat 11/7
7:54 pm-1:13 pm
2 stops17h 19m
Knoxville McGhee Tyson
Wed 11/11
7:35 pm-2:17 pm
1 stop18h 42m
$803
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Sat 1/16
10:05 am-11:45 am
3 stops25h 40m
Knoxville McGhee Tyson
Mon 1/18
7:10 pm-11:48 am
2 stops16h 38m
$809
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Mon 11/9
5:37 pm-11:59 pm
2 stops30h 22m
Knoxville McGhee Tyson
Fri 11/13
1:55 pm-9:59 am
1 stop20h 04m
$817
ColumbiaKnoxville
CAE Columbia Metropolitan - TYS Knoxville McGhee Tyson
CAETYS
Columbia Metropolitan
Sat 12/26
10:47 am-7:31 pm
2 stops8h 44m
Knoxville McGhee Tyson
Thu 12/31
9:26 am-8:33 pm
2 stops11h 07m
$852
Sorted by cheapest first
Compare providers for flights from Columbia to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbia-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbia-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbia to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Columbia with our price prediction graph.
CAE-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Columbia to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Newport
Bryson City
Murphy
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