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Myrtle Beach

$151+ Cheap flights from Knoxville to Myrtle Beach (TYS - MYR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MYR
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Knoxville to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$272
(Kiwi.com)

One-way from

$151
(American Airlines)

Popular in

January

Cheapest in

August

Average price

$938
Provider with most accurate pricing for Knoxville McGhee Tyson-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Myrtle Beach Intl flights.
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From Knoxville McGhee Tyson to Myrtle Beach Intl
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One-way flight from Knoxville McGhee Tyson to Myrtle Beach Intl
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Highest demand for flights based on searches. 32% potential increase in price ($197 potential increase over avg. RT price).
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Cheapest flight prices on average. 13% potential price decrease ($48 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Knoxville to Myrtle Beach

Cheapest flights from Knoxville to Myrtle Beach
Explore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/139:36 pm
TYS
-
MYR
1 stop10h 37m
Multiple Airlines
Fri 2/209:09 am
MYR
-
TYS
1 stop27h 55m
Multiple Airlines
Deal found 1/14$272
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:05 am
TYS
-
MYR
1 stop7h 05m
Southwest
Thu 4/161:45 pm
MYR
-
TYS
1 stop7h 30m
Southwest
Deal found 1/14$287
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:10 am
TYS
-
MYR
1 stop11h 16m
Multiple Airlines
Wed 5/277:51 pm
MYR
-
TYS
1 stop16h 22m
Multiple Airlines
Deal found 1/14$295
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:15 am
TYS
-
MYR
1 stop7h 40m
Multiple Airlines
Thu 2/199:09 am
MYR
-
TYS
1 stop27h 32m
Multiple Airlines
Deal found 1/13$297
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:02 pm
TYS
-
MYR
1 stop6h 35m
Multiple Airlines
Mon 6/82:28 pm
MYR
-
TYS
1 stop9h 06m
Multiple Airlines
Deal found 1/13$301
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:40 am
TYS
-
MYR
1 stop9h 59m
Multiple Airlines
Mon 3/236:37 pm
MYR
-
TYS
1 stop19h 33m
Multiple Airlines
Deal found 1/14$313
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:47 pm
TYS
-
MYR
1 stop6h 08m
American Airlines
Sun 2/225:10 am
MYR
-
TYS
1 stop6h 10m
American Airlines
Deal found 1/13$317
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/229:29 am
TYS
-
MYR
1 stop28h 44m
Multiple Airlines
Sun 1/251:07 pm
MYR
-
TYS
1 stop21h 03m
Multiple Airlines
Deal found 1/13$327
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:45 am
TYS
-
MYR
1 stop8h 25m
Southwest
Wed 5/277:35 am
MYR
-
TYS
2 stops12h 05m
Southwest
Deal found 1/14$329
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:35 am
TYS
-
MYR
1 stop4h 10m
Delta
Fri 2/206:55 pm
MYR
-
TYS
1 stop4h 57m
Delta
Deal found 1/15$332

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Knoxville to Myrtle Beach that are best for you.

Fly from

Knoxville

Fly to

Myrtle Beach

Route

Depart

Return

Price

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Fri 2/13

9:36 pm-8:13 am

1 stop10h 37m

Myrtle Beach Intl

Fri 2/20

9:09 am-1:04 pm

1 stop27h 55m

$272

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Mon 4/13

8:05 am-3:10 pm

1 stop7h 05m

Myrtle Beach Intl

Thu 4/16

1:45 pm-9:15 pm

1 stop7h 30m

$287

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Mon 2/16

7:15 am-2:55 pm

1 stop7h 40m

Myrtle Beach Intl

Thu 2/19

9:09 am-12:41 pm

1 stop27h 32m

$297

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Fri 3/20

7:40 am-5:39 pm

1 stop9h 59m

Myrtle Beach Intl

Mon 3/23

6:37 pm-2:10 pm

1 stop19h 33m

$313

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Fri 2/20

5:47 pm-11:55 pm

1 stop6h 08m

Myrtle Beach Intl

Sun 2/22

5:10 am-11:20 am

1 stop6h 10m

$317

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Fri 3/27

7:50 am-3:00 pm

1 stop7h 10m

Myrtle Beach Intl

Fri 4/3

3:35 pm-9:15 pm

1 stop5h 40m

$327

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Thu 1/22

9:29 am-2:13 pm

1 stop28h 44m

Myrtle Beach Intl

Sun 1/25

1:07 pm-10:10 am

1 stop21h 03m

$327

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Fri 2/6

6:05 am-9:48 am

1 stop3h 43m

Myrtle Beach Intl

Sun 2/8

7:19 pm-10:54 pm

1 stop3h 35m

$347

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Tue 2/17

4:04 pm-8:45 pm

1 stop4h 41m

$151

KnoxvilleMyrtle Beach

TYS - MYR

TYSMYR

Knoxville McGhee Tyson

Tue 2/17

4:04 pm-11:57 pm

2 stops31h 53m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 14 results
1
2

Compare providers for flights from Knoxville to Myrtle Beach

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Myrtle Beach in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Myrtle Beach flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Myrtle Beach flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Myrtle Beach flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Myrtle Beach flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Myrtle Beach

What is the cheapest month to book a flight from Knoxville to Myrtle Beach?

Currently, June is the cheapest month in which you can book a flight from Knoxville to Myrtle Beach (average of $174). Flying from Knoxville to Myrtle Beach in March is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Knoxville to Myrtle Beach, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,048 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,048 reviews
Delta
7.9
Good
8,048 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,129 reviews
Delta
7.9
Good
8,048 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Myrtle Beach?

    Southwest can get you from Knoxville to Myrtle Beach in just under 7h 05m. Your travel time can differ by up to . Airlines will cover a distance of 323 mi.

  • What are the cheapest airlines flying from Knoxville to Myrtle Beach round-trip?

    Delta, at $125, was found to be the cheapest airline from Knoxville to Myrtle Beach. An alternate airline flying to your destination would be American Airlines. Users have found that Delta is 69% cheaper than the other options available to this destination.

  • Can I find deals for flights from Knoxville to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Knoxville to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Myrtle Beach.

  • Can I find deals for business class flights from Knoxville to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Knoxville to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Myrtle Beach?

    Currently, June is the cheapest month in which you can book a flight from Knoxville to Myrtle Beach (average of $174). Flying from Knoxville to Myrtle Beach in March is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

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Top 2 airlines flying from Knoxville to Myrtle Beach

Discover the top 2 airlines that operate flights from Knoxville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$125Average$512FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$311FlexibilityNo cancel feeOn-time71%

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