$138+ Cheap flights from Knoxville to Myrtle Beach (TYS - MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MYR
Jun 10 — Jun 171
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Myrtle Beach
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Myrtle BeachExplore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:27 pm
TYS
- MYR
1 stop16h 12m
Multiple Airlines
Thu 6/44:22 pm
MYR
- TYS
2 stops29h 28m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:02 pm
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Fri 6/122:28 pm
MYR
- TYS
1 stop9h 06m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:33 pm
TYS
- MYR
1 stop4h 25m
Delta
Wed 6/106:00 am
MYR
- TYS
1 stop3h 53m
Delta
Deal found 5/11![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
TYS
- MYR
1 stop5h 25m
Southwest
Tue 6/162:10 pm
MYR
- TYS
1 stop7h 05m
Southwest
Deal found 5/8![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:00 am
TYS
- MYR
1 stop5h 50m
Southwest
Sat 10/37:55 am
MYR
- TYS
2 stops9h 45m
Southwest
Deal found 5/7![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:35 am
TYS
- MYR
1 stop3h 09m
Delta
Tue 7/76:00 am
MYR
- TYS
1 stop3h 36m
Delta
Deal found 5/7![Delta logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:02 pm
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Fri 6/192:28 pm
MYR
- TYS
1 stop9h 10m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:40 pm
TYS
- MYR
2 stops18h 34m
Multiple Airlines
Wed 7/153:17 pm
MYR
- TYS
1 stop20h 52m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:01 am
TYS
- MYR
1 stop4h 31m
American Airlines
Tue 7/76:50 am
MYR
- TYS
1 stop3h 48m
American Airlines
Deal found 5/10![American Airlines logo]()
$316
Best flights from Knoxville to Myrtle BeachDiscover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:00 am
TYS
- MYR
1 stop5h 50m
Southwest
Sat 10/37:55 am
MYR
- TYS
2 stops9h 45m
Southwest
Deal found 5/7![Southwest logo]()
$302
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:46 pm
TYS
- MYR
1 stop4h 13m
Delta
Mon 6/157:57 pm
MYR
- TYS
1 stop3h 57m
Delta
Deal found 5/11![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
TYS
- MYR
1 stop5h 25m
Southwest
Wed 7/152:10 pm
MYR
- TYS
1 stop7h 05m
Southwest
Deal found 5/11![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:40 am
TYS
- MYR
1 stop6h 45m
Southwest
Sat 6/203:50 pm
MYR
- TYS
1 stop5h 30m
Southwest
Deal found 5/7![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:33 pm
TYS
- MYR
1 stop4h 25m
Delta
Wed 6/106:00 am
MYR
- TYS
1 stop3h 53m
Delta
Deal found 5/10![Delta logo]()
$395
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
TYS
- MYR
2 stops13h 25m
Southwest
Tue 6/92:10 pm
MYR
- TYS
1 stop7h 05m
Southwest
Deal found 5/11![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:00 am
TYS
- MYR
2 stops9h 10m
Southwest
Sat 6/207:50 am
MYR
- TYS
2 stops11h 45m
Southwest
Deal found 5/8![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:40 am
TYS
- MYR
1 stop6h 45m
Southwest
Mon 6/152:00 pm
MYR
- TYS
2 stops7h 10m
Southwest
Deal found 5/7![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:40 am
TYS
- MYR
1 stop5h 30m
Southwest
Sat 6/63:50 pm
MYR
- TYS
1 stop5h 30m
Southwest
Deal found 5/7![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:40 am
TYS
- MYR
2 stops11h 55m
Southwest
Tue 6/98:30 am
MYR
- TYS
2 stops11h 50m
Southwest
Deal found 5/10![Southwest logo]()
$389
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:35 am
TYS
- MYR
2 stops14h 15m
Southwest
Fri 6/52:00 pm
MYR
- TYS
2 stops7h 10m
Southwest
Deal found 5/8![Southwest logo]()
$433
Last-minute flights from Knoxville to Myrtle BeachDiscover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated May 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:27 pm
TYS
- MYR
1 stop16h 12m
Multiple Airlines
Thu 6/44:22 pm
MYR
- TYS
2 stops29h 28m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$268
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:33 pm
TYS
- MYR
1 stop4h 25m
Delta
Wed 6/106:00 am
MYR
- TYS
1 stop3h 53m
Delta
Deal found 5/11![Delta logo]()
$295
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
TYS
- MYR
1 stop5h 25m
Southwest
Tue 6/162:10 pm
MYR
- TYS
1 stop7h 05m
Southwest
Deal found 5/8![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:00 am
TYS
- MYR
1 stop5h 25m
Southwest
Sat 6/133:50 pm
MYR
- TYS
1 stop5h 30m
Southwest
Deal found 5/7![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:46 pm
TYS
- MYR
1 stop4h 13m
Delta
Mon 6/157:57 pm
MYR
- TYS
1 stop3h 57m
Delta
Deal found 5/11![Delta logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:02 pm
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Fri 6/122:28 pm
MYR
- TYS
1 stop9h 06m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:02 pm
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Fri 6/192:28 pm
MYR
- TYS
1 stop9h 10m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:35 am
TYS
- MYR
1 stop3h 09m
Delta
Tue 7/76:00 am
MYR
- TYS
1 stop3h 36m
Delta
Deal found 5/7![Delta logo]()
$305
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:01 am
TYS
- MYR
1 stop4h 31m
American Airlines
Tue 7/76:50 am
MYR
- TYS
1 stop3h 48m
American Airlines
Deal found 5/10![American Airlines logo]()
$316
One-way flights from Knoxville to Myrtle BeachSearch for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:02 pm
TYS
- MYR
1 stop26h 35m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$138
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:00 am
TYS
- MYR
1 stop3h 44m
American Airlines
Deal found 5/10![American Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:02 pm
TYS
- MYR
1 stop6h 35m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$150
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:10 am
TYS
- MYR
2 stops11h 15m
Southwest
Deal found 5/10![Southwest logo]()
$159
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:05 am
TYS
- MYR
1 stop6h 25m
Southwest
Deal found 5/6![Southwest logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:45 pm
TYS
- MYR
2 stops42h 40m
Allegiant Air
Deal found 5/10![Allegiant Air logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:40 pm
TYS
- MYR
2 stops32h 28m
Allegiant Air
Deal found 5/8![Allegiant Air logo]()
$175
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:40 am
TYS
- MYR
2 stops12h 50m
Southwest
Deal found 5/7![Southwest logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:19 pm
TYS
- MYR
2 stops20h 46m
Allegiant Air
Deal found 5/10![Allegiant Air logo]()
$184
Find flight deals from Knoxville to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $268 (Kiwi.com) |
One-way from | $138 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $330 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Knoxville to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Wed 9/30
8:00 am-1:50 pm
1 stop5h 50m
Myrtle Beach Intl
Sat 10/3
7:55 am-5:40 pm
2 stops9h 45m
$302
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Sat 7/11
8:00 am-1:25 pm
1 stop5h 25m
Myrtle Beach Intl
Wed 7/15
2:10 pm-9:15 pm
1 stop7h 05m
$316
Quickest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Mon 6/8
7:46 pm-11:59 pm
1 stop4h 13m
Myrtle Beach Intl
Mon 6/15
7:57 pm-11:54 pm
1 stop3h 57m
$321
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 6/12
6:40 am-1:25 pm
1 stop6h 45m
Myrtle Beach Intl
Sat 6/20
3:50 pm-9:20 pm
1 stop5h 30m
$342
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Wed 6/3
7:05 am-8:30 pm
2 stops13h 25m
Myrtle Beach Intl
Tue 6/9
2:10 pm-9:15 pm
1 stop7h 05m
$347
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Sat 6/13
7:00 am-4:10 pm
2 stops9h 10m
Myrtle Beach Intl
Sat 6/20
7:50 am-7:35 pm
2 stops11h 45m
$347
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 6/12
6:40 am-1:25 pm
1 stop6h 45m
Myrtle Beach Intl
Mon 6/15
2:00 pm-9:10 pm
2 stops7h 10m
$348
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Sat 5/23
6:40 am-12:10 pm
1 stop5h 30m
Myrtle Beach Intl
Sat 6/6
3:50 pm-9:20 pm
1 stop5h 30m
$368
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 6/5
6:40 am-6:35 pm
2 stops11h 55m
Myrtle Beach Intl
Tue 6/9
8:30 am-8:20 pm
2 stops11h 50m
$389
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Wed 6/3
7:33 pm-11:58 pm
1 stop4h 25m
Myrtle Beach Intl
Wed 6/10
6:00 am-9:53 am
1 stop3h 53m
$395
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Myrtle Beach in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Knoxville with our price prediction graph.
TYS-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Myrtle Beach
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated May 11, 2026.
Read through reviews of airlines operating flights from Knoxville to Myrtle Beach, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Surfside Beach
Pawleys Island
Little River
Garden City Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Myrtle Beach flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Myrtle Beach
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Myrtle Beach by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Myrtle Beach by cabin class
Find flights from Knoxville to Myrtle Beach, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Myrtle Beach
Explore flights to Myrtle Beach departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
Knoxville and Myrtle Beach flights
Browse other Knoxville and Myrtle Beach flight options. Last updated on May 11, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Myrtle Beach
Discover the top 2 airlines that operate flights from Knoxville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$315 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$366 | FlexibilityNo cancel fee | On-timeN/A |