$124+ Cheap flights from Knoxville to Myrtle Beach (TYS - MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MYR
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Myrtle Beach
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Cheapest flights from Knoxville to Myrtle BeachExplore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 pm -
1 stop3h 21m
Fri 9/115:45 pm -
1 stop5h 05m
Deal found 8/6![American Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:28 pm -
1 stop14h 30m
Mon 10/261:48 pm -
1 stop27h 26m
Deal found 8/6![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:51 pm -
1 stop19h 14m
Fri 8/281:13 pm -
1 stop5h 52m
Deal found 8/8![Multiple Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 am -
2 stops8h 50m
Fri 9/113:20 pm -
1 stop4h 40m
Deal found 8/6![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:54 am -
1 stop6h 51m
Tue 9/83:53 pm -
1 stop18h 11m
Deal found 8/6![Multiple Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:25 pm -
1 stop3h 13m
Mon 8/315:15 pm -
1 stop5h 43m
Deal found 8/5![American Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:15 am -
1 stop5h 05m
Mon 9/147:25 pm -
1 stop3h 25m
Deal found 8/7![American Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:40 pm -
1 stop21h 37m
Fri 9/181:48 pm -
1 stop20h 26m
Deal found 8/5![Multiple Airlines logo]()
$282
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:10 am -
2 stops12h 30m
Mon 8/312:30 pm -
1 stop4h 05m
Deal found 8/5![Southwest logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop11h 40m
Mon 10/266:12 pm -
2 stops23h 02m
Deal found 8/10![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:52 pm -
1 stop16h 58m
Sun 8/232:58 pm -
1 stop28h 07m
Deal found 8/6![Multiple Airlines logo]()
$286
Best flights from Knoxville to Myrtle BeachDiscover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 am -
2 stops8h 50m
Fri 9/113:20 pm -
1 stop4h 40m
Deal found 8/6![Southwest logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:28 pm -
1 stop11h 40m
Mon 10/266:12 pm -
2 stops23h 02m
Deal found 8/10![Multiple Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:40 am -
1 stop4h 27m
Sun 9/136:58 pm -
1 stop4h 57m
Deal found 8/5![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:10 am -
2 stops12h 30m
Mon 8/312:30 pm -
1 stop4h 05m
Deal found 8/5![Southwest logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:46 pm -
2 stops20h 33m
Fri 9/42:36 pm -
1 stop8h 20m
Deal found 8/8![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:52 am -
1 stop24h 51m
Fri 9/111:48 pm -
1 stop20h 26m
Deal found 8/5![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:00 am -
2 stops26h 05m
Fri 9/181:48 pm -
1 stop20h 26m
Deal found 8/5![Multiple Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:25 pm -
2 stops14h 25m
Mon 10/261:25 pm -
2 stops9h 15m
Deal found 8/10![Southwest logo]()
$419
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am -
2 stops10h 40m
Sat 8/2911:45 am -
1 stop7h 35m
Deal found 8/10![Southwest logo]()
$458
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:15 am -
2 stops14h 10m
Tue 10/68:40 am -
2 stops12h 20m
Deal found 8/9![Southwest logo]()
$519
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am -
2 stops12h 15m
Sun 9/207:30 am -
2 stops13h 20m
Deal found 8/9![Southwest logo]()
$561
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:30 am -
1 stop5h 40m
Tue 9/297:50 am -
2 stops11h 10m
Deal found 8/8![Southwest logo]()
$595
Last-minute flights from Knoxville to Myrtle BeachDiscover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:08 pm -
1 stop12h 57m
Mon 8/248:41 pm -
1 stop12h 59m
Deal found 8/10![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:52 pm -
1 stop16h 58m
Sun 8/232:58 pm -
1 stop28h 07m
Deal found 8/6![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:51 pm -
1 stop19h 14m
Fri 8/281:13 pm -
1 stop5h 52m
Deal found 8/8![Multiple Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:25 pm -
1 stop3h 13m
Mon 8/315:15 pm -
1 stop5h 43m
Deal found 8/5![American Airlines logo]()
$272
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:10 am -
2 stops12h 30m
Mon 8/312:30 pm -
1 stop4h 05m
Deal found 8/5![Southwest logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:54 am -
1 stop6h 51m
Tue 9/83:53 pm -
1 stop18h 11m
Deal found 8/6![Multiple Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 pm -
1 stop3h 21m
Fri 9/115:45 pm -
1 stop5h 05m
Deal found 8/9![American Airlines logo]()
$211
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 am -
2 stops8h 50m
Fri 9/113:20 pm -
1 stop4h 40m
Deal found 8/6![Southwest logo]()
$267
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:15 am -
1 stop5h 05m
Mon 9/147:25 pm -
1 stop3h 25m
Deal found 8/7![American Airlines logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:40 pm -
1 stop21h 37m
Fri 9/181:48 pm -
1 stop20h 26m
Deal found 8/5![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:17 pm -
1 stop14h 41m
Sun 9/272:46 pm -
1 stop20h 46m
Deal found 8/10![Multiple Airlines logo]()
$292
One-way flights from Knoxville to Myrtle BeachSearch for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:30 am -
1 stop3h 17m
Deal found 8/7![Delta logo]()
$124
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:50 am -
2 stops8h 50m
Deal found 8/5![Southwest logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:52 pm -
1 stop16h 58m
Deal found 8/10![Multiple Airlines logo]()
$144
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:05 pm -
1 stop4h 33m
Deal found 8/6![American Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:08 pm -
2 stops18h 31m
Deal found 8/6![Multiple Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:29 pm -
1 stop15h 36m
Deal found 8/9![Multiple Airlines logo]()
$157
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:22 pm -
1 stop6h 16m
Deal found 8/9![American Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
2 stops10h 40m
Deal found 8/9![Southwest logo]()
$179
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:25 pm -
2 stops14h 20m
Deal found 8/7![Southwest logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:55 pm -
3 stops21h 30m
Deal found 8/5![Multiple Airlines logo]()
$193
Find flight deals from Knoxville to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (American Airlines) |
One-way from | $124 (Delta) |
Popular in | March |
Cheapest in | August |
Average price | $278 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Knoxville to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Sat 9/5
6:50 am-3:40 pm
2 stops8h 50m
Myrtle Beach Intl
Fri 9/11
3:20 pm-8:00 pm
1 stop4h 40m
$267
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Fri 8/28
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Mon 8/31
2:30 pm-6:35 pm
1 stop4h 05m
$283
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Fri 10/23
9:28 pm-9:08 am
1 stop11h 40m
Myrtle Beach Intl
Mon 10/26
6:12 pm-5:14 pm
2 stops23h 02m
$285
Quickest round-trip
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Tue 9/8
5:40 am-10:07 am
1 stop4h 27m
Myrtle Beach Intl
Sun 9/13
6:58 pm-11:55 pm
1 stop4h 57m
$297
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Wed 9/2
3:46 pm-12:19 pm
2 stops20h 33m
Myrtle Beach Intl
Fri 9/4
2:36 pm-10:56 pm
1 stop8h 20m
$310
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Fri 9/4
10:52 am-11:43 am
1 stop24h 51m
Myrtle Beach Intl
Fri 9/11
1:48 pm-10:14 am
1 stop20h 26m
$366
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Mon 9/14
8:00 am-10:05 am
2 stops26h 05m
Myrtle Beach Intl
Fri 9/18
1:48 pm-10:14 am
1 stop20h 26m
$370
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Fri 10/23
7:25 pm-9:50 am
2 stops14h 25m
Myrtle Beach Intl
Mon 10/26
1:25 pm-10:40 pm
2 stops9h 15m
$419
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Tue 8/25
7:00 am-5:40 pm
2 stops10h 40m
Myrtle Beach Intl
Sat 8/29
11:45 am-7:20 pm
1 stop7h 35m
$458
KnoxvilleMyrtle Beach
TYS Knoxville McGhee Tyson - MYR Myrtle Beach Intl
TYSMYR
Knoxville McGhee Tyson
Fri 10/2
7:15 am-9:25 pm
2 stops14h 10m
Myrtle Beach Intl
Tue 10/6
8:40 am-9:00 pm
2 stops12h 20m
$519
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Myrtle Beach in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Knoxville with our price prediction graph.
TYS-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated August 10, 2026.
Read through reviews of airlines operating flights from Knoxville to Myrtle Beach, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Food
7.2
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Pawleys Island
Sunset Beach
Garden City Beach
Surfside Beach
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Top 2 airlines flying from Knoxville to Myrtle Beach
Discover the top 2 airlines that operate flights from Knoxville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$366 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$336 | FlexibilityNo cancel fee | On-timeN/A |