$131+ Cheap flights from Knoxville to Myrtle Beach (TYS - MYR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MYR
Jul 27 — Aug 31
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Myrtle Beach with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Myrtle Beach
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Last-minute
One-way
Cheapest flights from Knoxville to Myrtle BeachExplore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
Explore the most affordable flight options available from Knoxville to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:25 pm
TYS
- MYR
1 stop3h 13m
American Airlines
Mon 8/175:15 pm
MYR
- TYS
1 stop3h 44m
American Airlines
Deal found 6/27![American Airlines logo]()
$217
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:04 pm
TYS
- MYR
1 stop3h 04m
American Airlines
Wed 10/75:31 am
MYR
- TYS
1 stop2h 51m
American Airlines
Deal found 6/26![American Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:43 pm
TYS
- MYR
1 stop4h 12m
Delta
Wed 7/221:51 pm
MYR
- TYS
1 stop3h 25m
Delta
Deal found 6/24![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:00 am
TYS
- MYR
2 stops6h 50m
Southwest
Tue 8/182:25 pm
MYR
- TYS
1 stop5h 25m
Southwest
Deal found 6/23![Southwest logo]()
$270
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:05 pm
TYS
- MYR
1 stop4h 33m
American Airlines
Sun 8/96:32 pm
MYR
- TYS
1 stop3h 18m
American Airlines
Deal found 6/26![American Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am
TYS
- MYR
1 stop6h 50m
Southwest
Wed 10/77:10 am
MYR
- TYS
2 stops11h 20m
Southwest
Deal found 6/23![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Mon 8/172:30 pm
MYR
- TYS
1 stop4h 05m
Southwest
Deal found 6/27![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:29 pm
TYS
- MYR
1 stop13h 21m
Multiple Airlines
Mon 8/171:13 pm
MYR
- TYS
1 stop9h 31m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:12 pm
TYS
- MYR
1 stop5h 18m
Delta
Mon 8/176:00 am
MYR
- TYS
1 stop3h 36m
Delta
Deal found 6/25![Delta logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:26 am
TYS
- MYR
2 stops26h 13m
Multiple Airlines
Fri 8/211:13 pm
MYR
- TYS
1 stop5h 52m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MYR
1 stop15h 36m
Multiple Airlines
Fri 8/213:31 pm
MYR
- TYS
1 stop21h 33m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$285
Best flights from Knoxville to Myrtle BeachDiscover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
Discover carefully curated flight deals from Knoxville to Myrtle Beach that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Mon 8/176:40 am
MYR
- TYS
2 stops11h 55m
Southwest
Deal found 6/27![Southwest logo]()
$290
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Mon 8/172:30 pm
MYR
- TYS
1 stop4h 05m
Southwest
Deal found 6/25![Southwest logo]()
$292
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:55 am
TYS
- MYR
1 stop6h 05m
Southwest
Sat 9/1211:45 am
MYR
- TYS
1 stop7h 35m
Southwest
Deal found 6/24![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:10 am
TYS
- MYR
1 stop10h 15m
Southwest
Fri 7/32:00 pm
MYR
- TYS
2 stops7h 10m
Southwest
Deal found 6/22![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Tue 9/292:25 pm
MYR
- TYS
1 stop5h 25m
Southwest
Deal found 6/25![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Mon 9/143:20 pm
MYR
- TYS
1 stop4h 35m
Southwest
Deal found 6/22![Southwest logo]()
$320
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 am
TYS
- MYR
2 stops12h 30m
Southwest
Sun 8/97:30 am
MYR
- TYS
2 stops13h 15m
Southwest
Deal found 6/22![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:30 am
TYS
- MYR
1 stop11h 05m
Southwest
Thu 7/302:00 pm
MYR
- TYS
2 stops7h 15m
Southwest
Deal found 6/25![Southwest logo]()
$348
Last-minute flights from Knoxville to Myrtle BeachDiscover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated June 27, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Myrtle Beach. Data last updated June 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:00 am
TYS
- MYR
1 stop3h 44m
American Airlines
Fri 7/34:16 pm
MYR
- TYS
1 stop3h 22m
American Airlines
Deal found 6/22![American Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:40 pm
TYS
- MYR
2 stops20h 37m
Multiple Airlines
Fri 7/108:41 pm
MYR
- TYS
1 stop26h 16m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:43 pm
TYS
- MYR
1 stop4h 12m
Delta
Wed 7/221:51 pm
MYR
- TYS
1 stop3h 25m
Delta
Deal found 6/24![Delta logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:05 pm
TYS
- MYR
1 stop6h 32m
Multiple Airlines
Mon 7/203:31 pm
MYR
- TYS
1 stop24h 39m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:08 pm
TYS
- MYR
1 stop19h 58m
Multiple Airlines
Mon 7/203:31 pm
MYR
- TYS
1 stop24h 39m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:15 am
TYS
- MYR
1 stop10h 30m
Multiple Airlines
Tue 7/213:53 pm
MYR
- TYS
1 stop26h 06m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:20 pm
TYS
- MYR
1 stop14h 45m
Multiple Airlines
Sat 7/256:23 pm
MYR
- TYS
1 stop25h 58m
Multiple Airlines
Deal found 6/26![Multiple Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:03 am
TYS
- MYR
1 stop6h 22m
American Airlines
Sat 7/258:44 pm
MYR
- TYS
1 stop3h 07m
American Airlines
Deal found 6/24![American Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
- MYR
1 stop10h 30m
Multiple Airlines
Thu 7/3011:52 am
MYR
- TYS
2 stops33h 23m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$305
One-way flights from Knoxville to Myrtle BeachSearch for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
Search for one-way flight options from Knoxville to Myrtle Beach. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:05 pm
TYS
- MYR
1 stop28h 40m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$131
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:00 am
TYS
- MYR
1 stop3h 46m
American Airlines
Deal found 6/23![American Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:20 pm
TYS
- MYR
1 stop14h 45m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:10 am
TYS
- MYR
2 stops14h 05m
Southwest
Deal found 6/22![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
- MYR
1 stop10h 30m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:40 pm
TYS
- MYR
2 stops32h 28m
Allegiant Air
Deal found 6/22![Allegiant Air logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:00 pm
TYS
- MYR
2 stops18h 39m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$160
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:49 pm
TYS
- MYR
1 stop4h 06m
Delta
Deal found 6/22![Delta logo]()
$169
Find flight deals from Knoxville to Myrtle Beach
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $217 (American Airlines) |
One-way from | $131 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $317 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Knoxville to Myrtle Beach that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Mon 8/10
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Mon 8/17
6:40 am-6:35 pm
2 stops11h 55m
$290
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Thu 8/13
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Mon 8/17
2:30 pm-6:35 pm
1 stop4h 05m
$292
Quickest round-trip
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Sun 9/6
8:55 am-3:00 pm
1 stop6h 05m
Myrtle Beach Intl
Sat 9/12
11:45 am-7:20 pm
1 stop7h 35m
$306
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Tue 6/30
8:10 am-6:25 pm
1 stop10h 15m
Myrtle Beach Intl
Fri 7/3
2:00 pm-9:10 pm
2 stops7h 10m
$306
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 9/25
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Tue 9/29
2:25 pm-7:50 pm
1 stop5h 25m
$312
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 9/11
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Mon 9/14
3:20 pm-7:55 pm
1 stop4h 35m
$320
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Thu 8/6
7:10 am-7:40 pm
2 stops12h 30m
Myrtle Beach Intl
Sun 8/9
7:30 am-8:45 pm
2 stops13h 15m
$331
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Fri 7/24
7:30 am-6:35 pm
1 stop11h 05m
Myrtle Beach Intl
Thu 7/30
2:00 pm-9:15 pm
2 stops7h 15m
$348
Cheapest one-way
Quickest one-way
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Tue 7/21
5:00 am-8:46 am
1 stop3h 46m
$133
KnoxvilleMyrtle Beach
TYS - MYR
TYSMYR
Knoxville McGhee Tyson
Wed 7/22
7:10 am-9:15 pm
2 stops14h 05m
$144
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Myrtle Beach
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Myrtle Beach in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Myrtle Beach flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Myrtle Beach
Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Knoxville with our price prediction graph.
TYS-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Myrtle Beach
Reviews of airlines servicing Myrtle Beach
Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated June 27, 2026.
Read through reviews of airlines operating flights from Knoxville to Myrtle Beach, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Myrtle Beach?
Book flights to Myrtle Beach if you plan to visit one of these locationsConway
Surfside Beach
Pawleys Island
Little River
Garden City Beach
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Other flights to Myrtle Beach
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Knoxville and Myrtle Beach flights
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Top 2 airlines flying from Knoxville to Myrtle Beach
Discover the top 2 airlines that operate flights from Knoxville to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$366 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$537 | FlexibilityNo cancel fee | On-timeN/A |