$33+ Cheap flights from Myrtle Beach to Louisville (MYR - SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/13. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SDF
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Louisville with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Louisville
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Cheapest flights from Myrtle Beach to LouisvilleExplore the most affordable flight options available from Myrtle Beach to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from Myrtle Beach to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Sat 7/111:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Deal found 6/4![Allegiant Air logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:53 pm
MYR
- SDF
1 stop21h 22m
Multiple Airlines
Sat 7/111:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:53 pm
MYR
- SDF
1 stop19h 33m
Multiple Airlines
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:51 pm
MYR
- SDF
1 stop21h 24m
Multiple Airlines
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$217
Best flights from Myrtle Beach to LouisvilleDiscover carefully curated flight deals from Myrtle Beach to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from Myrtle Beach to Louisville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:58 pm
MYR
- SDF
2 stops34h 48m
Multiple Airlines
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$223
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:05 pm
MYR
- SDF
1 stop4h 10m
Southwest
Mon 7/275:50 am
SDF
- MYR
1 stop4h 05m
Southwest
Deal found 6/5![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:44 pm
MYR
- SDF
1 stop3h 50m
American Airlines
Sun 7/55:04 am
SDF
- MYR
1 stop3h 32m
American Airlines
Deal found 6/8![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:54 pm
MYR
- SDF
1 stop5h 30m
Delta
Sun 7/56:00 am
SDF
- MYR
1 stop4h 44m
Delta
Deal found 6/5![Delta logo]()
$392
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/113:50 pm
MYR
- SDF
2 stops7h 35m
Southwest
Tue 7/148:45 am
SDF
- MYR
2 stops11h 50m
Southwest
Deal found 6/6![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:50 pm
MYR
- SDF
2 stops7h 35m
Southwest
Sat 7/255:05 pm
SDF
- MYR
1 stop3h 40m
Southwest
Deal found 6/4![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:30 am
MYR
- SDF
2 stops12h 00m
Southwest
Sat 7/1811:50 am
SDF
- MYR
2 stops8h 55m
Southwest
Deal found 6/6![Southwest logo]()
$380
Last-minute flights from Myrtle Beach to LouisvilleDiscover last-minute flight deals from Myrtle Beach to Louisville. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Louisville. Data last updated June 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Sat 7/111:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:53 pm
MYR
- SDF
1 stop21h 22m
Multiple Airlines
Sat 7/111:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:53 pm
MYR
- SDF
1 stop19h 33m
Multiple Airlines
Sat 7/181:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:37 am
MYR
- SDF
Nonstop1h 35m
Allegiant Air
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Allegiant Air
Deal found 6/4![Allegiant Air logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:51 pm
MYR
- SDF
1 stop21h 24m
Multiple Airlines
Sat 7/251:02 pm
SDF
- MYR
Nonstop1h 30m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$217
One-way flights from Myrtle Beach to LouisvilleSearch for one-way flight options from Myrtle Beach to Louisville. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from Myrtle Beach to Louisville. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:39 am
MYR
- SDF
Nonstop1h 37m
Allegiant Air
Deal found 6/3![Allegiant Air logo]()
$33
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:34 am
MYR
- SDF
1 stop4h 03m
United Airlines
Deal found 6/8![United Airlines logo]()
$174
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/312:00 pm
MYR
- SDF
2 stops8h 30m
Southwest
Deal found 6/8![Southwest logo]()
$179
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:10 pm
MYR
- SDF
2 stops8h 25m
Southwest
Deal found 6/8![Southwest logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:05 pm
MYR
- SDF
2 stops35h 31m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/134:21 pm
MYR
- SDF
1 stop27h 48m
Breeze Airways
Deal found 6/3![Breeze Airways logo]()
$223
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:08 pm
MYR
- SDF
1 stop5h 15m
United Airlines
Deal found 6/7![United Airlines logo]()
$230
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
MYR
- SDF
1 stop5h 53m
Delta
Deal found 6/4![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:21 pm
MYR
- SDF
1 stop27h 48m
Breeze Airways
Deal found 6/5![Breeze Airways logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:17 pm
MYR
- SDF
3 stops40h 55m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$261
Find flight deals from Myrtle Beach to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $155 (Kiwi.com) |
One-way from | $33 (Kiwi.com) |
Popular in | December |
Cheapest in | May |
Average price | $392 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Louisville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Sat 7/18
9:58 pm-8:46 am
2 stops34h 48m
Louisville Intl
Sat 7/25
1:02 pm-2:32 pm
Nonstop1h 30m
$223
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Wed 7/22
7:05 pm-11:15 pm
1 stop4h 10m
Louisville Intl
Mon 7/27
5:50 am-9:55 am
1 stop4h 05m
$321
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Sat 7/11
3:50 pm-11:25 pm
2 stops7h 35m
Louisville Intl
Tue 7/14
8:45 am-8:35 pm
2 stops11h 50m
$337
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Sat 7/18
3:50 pm-11:25 pm
2 stops7h 35m
Louisville Intl
Sat 7/25
5:05 pm-8:45 pm
1 stop3h 40m
$362
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Tue 7/14
8:30 am-8:30 pm
2 stops12h 00m
Louisville Intl
Sat 7/18
11:50 am-8:45 pm
2 stops8h 55m
$380
Quickest round-trip
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Thu 7/2
8:44 pm-12:34 am
1 stop3h 50m
Louisville Intl
Sun 7/5
5:04 am-8:36 am
1 stop3h 32m
$387
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Thu 7/2
1:54 pm-7:24 pm
1 stop5h 30m
Louisville Intl
Sun 7/5
6:00 am-10:44 am
1 stop4h 44m
$392
Cheapest one-way
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Fri 7/31
8:10 pm-12:30 am
1 stop4h 20m
$174
Quickest one-way
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Wed 7/15
10:34 am-2:37 pm
1 stop4h 03m
$174
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Wed 7/15
2:10 pm-10:35 pm
2 stops8h 25m
$199
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Louisville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Louisville in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from Myrtle Beach with our price prediction graph.
MYR-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Louisville
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated June 8, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Myrtle Beach to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsCorydon
Shepherdsville
Elizabethtown
Jeffersonville
Bardstown
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Other flights to Louisville
Explore flights to Louisville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Myrtle Beach and Louisville flights
Browse other Myrtle Beach and Louisville flight options. Last updated on June 8, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on June 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Louisville
Discover the top 2 airlines that operate flights from Myrtle Beach to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$352 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$260 | Average$370 | FlexibilityNo cancel fee | On-time71% |