What are the cheapest airlines flying from Myrtle Beach to Santo Domingo round-trip?

Spirit Airlines, at $275, was found to be the cheapest airline from Myrtle Beach to Santo Domingo.Alternate airlines to your destination round-trip include American Airlines and Delta. Spirit Airlines is currently priced 40% below the average price you’ll pay for this route.

What are the cheapest flights from Myrtle Beach to Santo Domingo?

While on average a flight from Myrtle Beach to Santo Domingo is generally $599, our data shows the cheapest flight currently is $131. When looking at the most popular route, (Myrtle Beach Intl - Santo Domingo Las Americas), you can expect to pay $275 for that flight.

Can I find flights from Myrtle Beach to Santo Domingo for under $300 on Cheapflights?

Yes, there are multiple flights from Myrtle Beach to Santo Domingo for under $300. The cheapest flight booked recently is on Spirit Airlines for just $275, but on average you can expect to pay $486.

Which airlines flying from Myrtle Beach Intl to Santo Domingo Las Americas have flexible changes due to COVID-19?

Spirit Airlines is one of the carriers that may have flexible change policies. You can use our site to filter for other airlines that may also have this kind of flexibility.

What is the cheapest day to fly round-trip from Myrtle Beach to Santo Domingo?

It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.

What is the cheapest month to fly from Myrtle Beach to Santo Domingo?

Our data shows that January tends to be the cheapest month to fly to Santo Domingo from Myrtle Beach. Users have commonly found prices around $459 for the month, but tickets can be as low as $284. Due to multiple factors, prepare for potentially higher prices in March.

When is the cheapest time to fly from Myrtle Beach to Santo Domingo (MYR - SDQ)?

Unlike in the morning, when flights are generally more expensive, you can save up to 35% on flights from Myrtle Beach to Santo Domingo by exploring options for tickets at noon.

What does MYR to SDQ mean?

Great question - MYR to SDQ just means Myrtle Beach Intl Airport to Santo Domingo Las Americas Airport. Now you’ll know what these unique codes when you look for flights!

Flights from Myrtle Beach, SC to Santo Domingo, the Dominican Republic from $275

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MYR — SDQ

Mar 27 — Apr 31

Round-tripOne-way

1 adult, Economy

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Cheap flights from Myrtle Beach to Santo Domingo in March, April 2023

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 10m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

6h 19m

$275

Spirit Airlines

Pick Dates

Deal found 3/20

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

12h 42m

$312

Spirit Airlines

Pick Dates

Deal found 3/20

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

14h 29m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

8h 55m

$339

Spirit Airlines

Pick Dates

Deal found 3/20

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

20h 37m

$374

Spirit Airlines

Pick Dates

Deal found 3/20

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

3 stops

30h 17m

$495

Multiple Airlines

Pick Dates

Deal found 3/20

Myrtle Beach to Santo Domingo 2023 flight deals

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 10m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

6h 19m

$275

Spirit Airlines

Pick Dates

Deal found 3/20

May 5 - May 10

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 55m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$293

Spirit Airlines

Pick Dates

Deal found 3/22

May 5 - May 11

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 55m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

18h 13m

$310

Spirit Airlines

Pick Dates

Deal found 3/22

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

12h 42m

$312

Spirit Airlines

Pick Dates

Deal found 3/20

May 10 - May 23

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

11h 04m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$328

Spirit Airlines

Pick Dates

Deal found 3/21

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

14h 29m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

8h 55m

$339

Spirit Airlines

Pick Dates

Deal found 3/20

May 10 - May 23

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

11h 02m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$348

Spirit Airlines

Pick Dates

Deal found 3/21

May 10 - May 24

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

11h 02m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

7h 12m

$359

Spirit Airlines

Pick Dates

Deal found 3/21

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

20h 37m

$374

Spirit Airlines

Pick Dates

Deal found 3/20

Cheap Spirit Airlines flights from Myrtle Beach to Santo Domingo

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 10m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

6h 19m

$275

Spirit Airlines

Pick Dates

Deal found 3/20

May 5 - May 10

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 55m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$293

Spirit Airlines

Pick Dates

Deal found 3/22

May 5 - May 11

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

8h 55m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

18h 13m

$310

Spirit Airlines

Pick Dates

Deal found 3/22

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

12h 42m

$312

Spirit Airlines

Pick Dates

Deal found 3/20

May 10 - May 23

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

1 stop

11h 04m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$328

Spirit Airlines

Pick Dates

Deal found 3/21

Apr 26 - May 2

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

14h 29m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

8h 55m

$339

Spirit Airlines

Pick Dates

Deal found 3/20

May 10 - May 23

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

11h 02m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

5h 57m

$348

Spirit Airlines

Pick Dates

Deal found 3/21

May 10 - May 24

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

11h 02m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

1 stop

7h 12m

$359

Spirit Airlines

Pick Dates

Deal found 3/21

Apr 26 - May 3

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

8h 57m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

20h 37m

$374

Spirit Airlines

Pick Dates

Deal found 3/20

Cheap American Airlines flights from Myrtle Beach to Santo Domingo

May 5 - May 11

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

17h 35m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

18h 00m

$654

American Airlines

Pick Dates

Deal found 3/22

Jun 17 - Jun 24

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

2 stops

15h 38m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

20h 14m

$709

American Airlines

Pick Dates

Deal found 3/21

May 5 - May 11

MYR

Myrtle Beach Intl

SDQ

Santo Domingo Las Americas

3 stops

10h 16m

SDQ

Santo Domingo Las Americas

MYR

Myrtle Beach Intl

2 stops

9h 24m

$4,358

American Airlines

Pick Dates

Deal found 3/22

Find flights from Myrtle Beach to Santo Domingo within your budget

Fly from

Fly to

Budget

$275 - $956

Route

Depart

Return

Price

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-04-26

1 stop8h 10m

Santo Domingo Las Americas

2023-05-03

1 stop6h 19m

$275

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-05-05

1 stop8h 55m

Santo Domingo Las Americas

2023-05-10

1 stop5h 57m

$293

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-05-05

1 stop8h 55m

Santo Domingo Las Americas

2023-05-11

1 stop18h 13m

$310

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-04-26

2 stops8h 57m

Santo Domingo Las Americas

2023-05-02

1 stop12h 42m

$312

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-05-10

1 stop11h 04m

Santo Domingo Las Americas

2023-05-23

1 stop5h 57m

$328

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-04-26

2 stops8h 57m

Santo Domingo Las Americas

2023-05-03

3 stops30h 17m

$495

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-05-05

2 stops17h 35m

Santo Domingo Las Americas

2023-05-11

2 stops18h 00m

$654

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-05-05

1 stop7h 22m

Santo Domingo Las Americas

2023-05-11

2 stops20h 20m

$734

Pick Dates

Myrtle Beach IntlSanto Domingo Las Americas

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

2023-06-17

1 stop7h 09m

Santo Domingo Las Americas

2023-06-24

1 stop21h 45m

$956

Pick Dates

Flights are sorted by cheapest first

Deals found on 3/20

Reviews of Airlines Servicing Santo Domingo

Delta

8.0

Very good

2,333 reviews

Check prices

Reviews

1 / 10

Few on the plane on Saturday night. Lots of space. Crew was great.

Delta

8.0

Very good

2,333 reviews

Delta

8.0

Very good

2,333 reviews

Check prices

Reviews

1 / 10

Few on the plane on Saturday night. Lots of space. Crew was great.

United Airlines

7.6

Good

1,427 reviews

Delta

8.0

Very good

2,333 reviews

Check prices

Reviews

1 / 10

Few on the plane on Saturday night. Lots of space. Crew was great.

American Airlines

7.4

Good

1,743 reviews

Delta

8.0

Very good

2,333 reviews

Check prices

Reviews

1 / 10

Few on the plane on Saturday night. Lots of space. Crew was great.

Spirit Airlines

6.9

Okay

758 reviews

Delta

8.0

Very good

2,333 reviews

Check prices

Reviews

1 / 10

Few on the plane on Saturday night. Lots of space. Crew was great.

Related info for your journey

Alternative routes for Myrtle Beach to Santo Domingo

Charleston to Punta Canafrom $241 pp

Myrtle Beach to Punta Canafrom $370 pp

Charleston to Santo Domingofrom $468 pp

Charleston to Santiago de los Caballerosfrom $530 pp

Greenville to Santo Domingofrom $619 pp

Columbia to Santo Domingofrom $630 pp

Top airline flying from Myrtle Beach to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time	COVID-19 safety
Spirit Airlines	Cheapest$284	Average$423	FlexibilityNo cancel fee	On-time65%	COVID-19 safety	Search Spirit Airlines flights

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Cheap flights from Myrtle Beach (MYR) to Santo Domingo (SDQ) from $275

What is the cheapest day to fly round-trip from Myrtle Beach to Santo Domingo?

What is the cheapest month to fly from Myrtle Beach to Santo Domingo?

When is the cheapest time to fly from Myrtle Beach to Santo Domingo (MYR - SDQ)?

Cheap flights from Myrtle Beach to Santo Domingo in March, April 2023

The best prices found for MYR to SDQ flights for March, April

Myrtle Beach to Santo Domingo 2023 flight deals

Cheap flights to Santo Domingo from Myrtle Beach found for this year

Cheap Spirit Airlines flights from Myrtle Beach to Santo Domingo

Cheap American Airlines flights from Myrtle Beach to Santo Domingo

Find flights from Myrtle Beach to Santo Domingo within your budget

Use the slider to find flights from Myrtle Beach to Santo Domingo that fit your budget.

Reviews of Airlines Servicing Santo Domingo

Related info for your journey

Useful info, stats and facts about Myrtle Beach to Santo Domingo flights.

Which airlines flying from Myrtle Beach Intl to Santo Domingo Las Americas have flexible changes due to COVID-19?

Can I find flights from Myrtle Beach to Santo Domingo for under $300 on Cheapflights?

What are the cheapest airlines flying from Myrtle Beach to Santo Domingo round-trip?

What are the cheapest flights from Myrtle Beach to Santo Domingo?

What does MYR to SDQ mean?

Other flights from Myrtle Beach

Other flights to Santo Domingo

Flights to Santo Domingo from Myrtle Beach

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Alternative routes for Myrtle Beach to Santo Domingo

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Top airline flying from Myrtle Beach to Santo Domingo

The chart below displays the airlines Cheapflights users traveling from Myrtle Beach to Santo Domingo choose most often. Cheapest and average prices are based on aggregated data from the past 12 months.

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