$238+ Cheap flights from Myrtle Beach (MYR) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/7. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SDQ
Jul 19 — Jul 261
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Santo Domingo
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Cheapest flights from Myrtle Beach to Santo DomingoExplore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 19, 2026.
This Priceline deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:28 pm
MYR
- SDQ
1 stop16h 38m
Frontier
Sat 9/512:21 pm
SDQ
- MYR
1 stop23h 28m
Frontier
Deal found 6/15![Frontier logo]()
$380
This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:08 am
MYR
- SDQ
2 stops10h 26m
American Airlines
Tue 9/229:30 am
SDQ
- MYR
2 stops9h 15m
American Airlines
Deal found 6/17![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am
MYR
- SDQ
2 stops12h 44m
American Airlines
Sat 9/54:24 pm
SDQ
- MYR
2 stops19h 58m
American Airlines
Deal found 6/15![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:07 pm
MYR
- SDQ
2 stops15h 05m
American Airlines
Sat 11/214:59 pm
SDQ
- MYR
2 stops16h 40m
American Airlines
Deal found 6/16![American Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
MYR
- SDQ
1 stop7h 27m
Delta
Sat 9/192:56 pm
SDQ
- MYR
1 stop6h 46m
Delta
Deal found 6/17![Delta logo]()
$600
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:59 pm
MYR
- SDQ
2 stops23h 26m
Delta
Fri 9/257:40 pm
SDQ
- MYR
2 stops19h 25m
Delta
Deal found 6/17![Delta logo]()
$605
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am
MYR
- SDQ
1 stop7h 41m
Delta
Sat 9/192:56 pm
SDQ
- MYR
1 stop6h 46m
Delta
Deal found 6/17![Delta logo]()
$625
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
MYR
- SDQ
1 stop7h 41m
Delta
Sat 9/192:56 pm
SDQ
- MYR
1 stop6h 46m
Delta
Deal found 6/17![Delta logo]()
$630
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:59 pm
MYR
- SDQ
1 stop16h 56m
United Airlines
Tue 9/223:20 pm
SDQ
- MYR
1 stop17h 39m
United Airlines
Deal found 6/17![United Airlines logo]()
$670
Best flights from Myrtle Beach to Santo DomingoDiscover carefully curated flight deals from Myrtle Beach to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
Discover carefully curated flight deals from Myrtle Beach to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 19, 2026.
This Priceline deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:28 pm
MYR
- SDQ
1 stop16h 38m
Frontier
Sat 9/512:21 pm
SDQ
- MYR
1 stop23h 28m
Frontier
Deal found 6/15![Frontier logo]()
$380
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:07 pm
MYR
- SDQ
2 stops15h 05m
American Airlines
Sat 11/214:59 pm
SDQ
- MYR
2 stops16h 40m
American Airlines
Deal found 6/14![American Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
MYR
- SDQ
1 stop7h 27m
Delta
Mon 9/212:56 pm
SDQ
- MYR
1 stop8h 34m
Delta
Deal found 6/17![Delta logo]()
$600
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:59 pm
MYR
- SDQ
1 stop16h 56m
United Airlines
Tue 9/223:20 pm
SDQ
- MYR
1 stop17h 39m
United Airlines
Deal found 6/17![United Airlines logo]()
$670
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
MYR
- SDQ
1 stop7h 41m
Delta
Fri 9/257:40 pm
SDQ
- MYR
2 stops19h 25m
Delta
Deal found 6/17![Delta logo]()
$605
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:59 pm
MYR
- SDQ
2 stops17h 21m
Delta
Thu 9/247:40 pm
SDQ
- MYR
2 stops22h 23m
Delta
Deal found 6/17![Delta logo]()
$605
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:00 am
MYR
- SDQ
1 stop11h 46m
United Airlines
Wed 10/216:00 am
SDQ
- MYR
1 stop12h 12m
United Airlines
Deal found 6/18![United Airlines logo]()
$730
This Delta deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
MYR
- SDQ
1 stop7h 27m
Delta
Tue 9/227:40 pm
SDQ
- MYR
2 stops16h 14m
Delta
Deal found 6/17![Delta logo]()
$605
Last-minute flights from Myrtle Beach to Santo DomingoDiscover last-minute flight deals from Myrtle Beach to Santo Domingo. Data last updated June 19, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Santo Domingo. Data last updated June 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:50 am
MYR
- SDQ
2 stops16h 05m
American Airlines
Thu 7/97:40 pm
SDQ
- MYR
2 stops15h 42m
American Airlines
Deal found 6/18![American Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:00 am
MYR
- SDQ
1 stop12h 46m
United Airlines
Thu 7/93:20 pm
SDQ
- MYR
1 stop17h 44m
United Airlines
Deal found 6/18![United Airlines logo]()
$745
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:28 pm
MYR
- SDQ
1 stop16h 38m
Multiple Airlines
Thu 7/912:18 pm
SDQ
- MYR
2 stops25h 48m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$777
One-way flights from Myrtle Beach to Santo DomingoSearch for one-way flight options from Myrtle Beach to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
Search for one-way flight options from Myrtle Beach to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 19, 2026.
This Priceline deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:23 pm
MYR
- SDQ
1 stop16h 40m
Frontier
Deal found 6/19![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:07 pm
MYR
- SDQ
2 stops37h 56m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:53 pm
MYR
- SDQ
3 stops43h 10m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:21 pm
MYR
- SDQ
2 stops18h 42m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:02 pm
MYR
- SDQ
3 stops43h 01m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$428
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:23 pm
MYR
- SDQ
1 stop16h 40m
Frontier
Deal found 6/19![Frontier logo]()
$433
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/52:58 pm
MYR
- SDQ
2 stops25h 31m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:23 pm
MYR
- SDQ
1 stop16h 40m
Frontier
Deal found 6/19![Frontier logo]()
$495
Find flight deals from Myrtle Beach to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $380 (Priceline) |
One-way from | $238 (Priceline) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 19, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Tue 8/25
6:28 pm-11:06 am
1 stop16h 38m
Santo Domingo Las Americas
Sat 9/5
12:21 pm-11:49 am
1 stop23h 28m
$380
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Sat 11/14
8:07 pm-12:12 pm
2 stops15h 05m
Santo Domingo Las Americas
Sat 11/21
4:59 pm-8:39 am
2 stops16h 40m
$585
Quickest round-trip
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Sat 9/12
6:00 am-1:27 pm
1 stop7h 27m
Santo Domingo Las Americas
Mon 9/21
2:56 pm-11:30 pm
1 stop8h 34m
$600
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Fri 9/18
6:00 am-1:41 pm
1 stop7h 41m
Santo Domingo Las Americas
Fri 9/25
7:40 pm-3:05 pm
2 stops19h 25m
$605
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Wed 9/16
6:59 pm-12:20 pm
2 stops17h 21m
Santo Domingo Las Americas
Thu 9/24
7:40 pm-6:03 pm
2 stops22h 23m
$605
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Sat 9/12
6:00 am-1:27 pm
1 stop7h 27m
Santo Domingo Las Americas
Tue 9/22
7:40 pm-11:54 am
2 stops16h 14m
$605
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Tue 9/15
6:59 pm-11:55 am
1 stop16h 56m
Santo Domingo Las Americas
Tue 9/22
3:20 pm-8:59 am
1 stop17h 39m
$670
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Mon 10/19
11:00 am-10:46 pm
1 stop11h 46m
Santo Domingo Las Americas
Wed 10/21
6:00 am-6:12 pm
1 stop12h 12m
$730
Cheapest one-way
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Thu 7/9
9:07 pm-11:03 am
2 stops37h 56m
$291
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Tue 7/7
4:13 pm-4:29 pm
2 stops24h 16m
$361
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santo Domingo in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Myrtle Beach with our price prediction graph.
MYR-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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