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Santo Domingo

$139+ Cheap flights from Myrtle Beach (MYR) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SDQ
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$399
(FlightHub)

One-way from

$139
(SmartFares)

Popular in

December

Cheapest in

February
From Myrtle Beach Intl to Santo Domingo Las Americas
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One-way flight from Myrtle Beach Intl to Santo Domingo Las Americas
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Highest demand for flights based on searches. 4% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
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Find flight deals from Myrtle Beach to Santo Domingo

Cheapest flights from Myrtle Beach to Santo Domingo
Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1610:40 amMYR - SDQ
1 stop24h 09mFrontier
Sun 7/2012:04 pmSDQ - MYR
1 stop9h 33mFrontier
Deal found 7/2$399
This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1610:40 amMYR - SDQ
1 stop24h 09mMultiple Airlines
Sun 7/2010:55 amSDQ - MYR
2 stops11h 22mMultiple Airlines
Deal found 7/2$454
This FlightHub deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/166:10 amMYR - SDQ
2 stops27h 40mSpirit Airlines
Sun 7/2010:55 amSDQ - MYR
2 stops11h 22mSpirit Airlines
Deal found 7/2$495

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.

Fly from

Myrtle Beach

Fly to

Santo Domingo

Route

Depart

Return

Price

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Wed 7/16

10:40 am-10:49 am

1 stop24h 09m

Santo Domingo Las Americas

Sun 7/20

12:04 pm-9:37 pm

1 stop9h 33m

$399

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Wed 7/16

10:40 am-10:49 am

1 stop24h 09m

Santo Domingo Las Americas

Sun 7/20

10:55 am-10:17 pm

2 stops11h 22m

$454

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Wed 7/16

6:10 am-9:50 am

2 stops27h 40m

Santo Domingo Las Americas

Sun 7/20

10:55 am-10:17 pm

2 stops11h 22m

$495

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 8/16

6:45 am-11:56 am

1 stop5h 11m

$139

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 8/16

6:31 pm-10:45 am

1 stop16h 14m

$205

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 7/13

4:12 pm-9:15 am

2 stops17h 03m

$333

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 7/13

6:00 am-1:12 pm

1 stop7h 12m

$497

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 7/13

5:36 pm-1:50 am

1 stop8h 14m

$621

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Myrtle Beach to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santo Domingo

What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Santo Domingo (average of $362). Flying from Myrtle Beach to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SDQ?

Find hourly flight availability from Myrtle Beach to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Santo Domingo as you normally would.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Myrtle Beach to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,970 reviews
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,845 reviews
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,094 reviews
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,284 reviews
Delta
8.0
Very good
7,970 reviews

Crew

8.5

Food

7.3

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Myrtle Beach to Santo Domingo round-trip?

    Frontier, at $399, was found to be the cheapest airline from Myrtle Beach to Santo Domingo. An alternate airline flying to your destination would be Spirit Airlines. Frontier is currently priced 34% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Myrtle Beach to Santo Domingo are Spirit Airlines ($139), American Airlines ($333), and Delta ($497).

  • Can I find deals for flights from Myrtle Beach to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santo Domingo.

  • Can I find deals for business class flights from Myrtle Beach to Santo Domingo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Santo Domingo (average of $362). Flying from Myrtle Beach to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Myrtle Beach to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Myrtle Beach to Santo Domingo

Discover the top 2 airlines that operate flights from Myrtle Beach to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$300Average$453FlexibilityNo cancel feeOn-time65%
DeltaCheapest$549Average$813FlexibilityNo cancel feeOn-timeN/A

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