Dominican Republic

$275+ Cheap flights from Myrtle Beach (MYR) to the Dominican Republic

MYR — PUJ
Oct 5 — Oct 121
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Cheap flight deals from Myrtle Beach to Dominican Republic

Cheapest flights from Myrtle Beach to Dominican Republic

Sat 10/35:58 pm -
1 stop14h 56m
Sat 10/106:25 pm -
2 stops14h 22m
Deal found 9/4$523
Sat 10/175:58 pm -
1 stop14h 56m
Sat 10/241:59 pm -
2 stops18h 48m
Deal found 9/2$560
Sat 10/175:58 pm -
1 stop14h 56m
Tue 10/201:59 pm -
2 stops18h 51m
Deal found 9/2$599
Sat 10/1712:30 pm -
1 stop10h 16m
Tue 10/201:10 pm -
1 stop20h 19m
Deal found 9/2$599
Fri 10/26:12 pm -
2 stops46h 49m
Fri 10/91:10 pm -
1 stop19h 40m
Deal found 9/4$624
Tue 12/16:41 pm -
1 stop19h 56m
Tue 12/85:33 pm -
1 stop20h 30m
Deal found 9/5$641
Mon 10/265:00 am -
1 stop5h 39m
Mon 11/24:11 pm -
1 stop7h 18m
Deal found 9/5$644
Sun 12/132:46 pm -
2 stops22h 54m
Sun 12/2011:35 am -
1 stop22h 10m
Deal found 9/2$669
Sun 12/138:35 pm -
2 stops18h 16m
Sun 12/206:00 pm -
2 stops17h 41m
Deal found 9/2$687
Fri 10/306:00 am -
1 stop7h 41m
Tue 11/103:55 pm -
1 stop8h 40m
Deal found 9/2$695
Fri 10/305:00 am -
2 stops10h 20m
Tue 11/107:00 am -
2 stops14h 57m
Deal found 8/31$696
Mon 11/211:27 am -
1 stop11h 19m
Fri 11/64:18 pm -
1 stop25h 53m
Deal found 9/1$771

Find flight deals from Myrtle Beach to Dominican Republic

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$456
(Southwest)

One-way from

$275
(Kiwi.com)

Popular in

June

Cheapest in

January

Average price

$656
Provider with most accurate pricing for Myrtle Beach Intl-Punta Cana flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Punta Cana flights.
From Myrtle Beach Intl to Dominican Republic
One-way flight from Myrtle Beach Intl to Dominican Republic
Highest demand for flights based on searches. 16% potential increase in price ($140 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in September 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to the Dominican Republic that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Wed 11/4

5:58 pm-5:25 pm

3 stops22h 27m

Punta Cana

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$275

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Thu 9/17

2:46 pm-11:36 am

2 stops20h 50m

Santo Domingo Las Americas

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$312

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Sun 11/1

8:35 pm-3:51 pm

2 stops18h 16m

Punta Cana

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$324
Quickest round-trip

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Thu 9/17

12:00 pm-10:46 pm

1 stop10h 46m

Santo Domingo Las Americas

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$343

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Fri 1/15

6:12 pm-2:30 pm

1 stop19h 18m

Punta Cana

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$383

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Tue 11/24

8:44 pm-3:48 pm

2 stops18h 04m

Punta Cana

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$422

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Fri 1/15

5:11 pm-2:30 pm

3 stops20h 19m

Punta Cana

Wed 12/31

12:00 am-11:30 pm

Nonstop0h 00m

$435

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Mon 3/1

8:10 am-3:35 pm

1 stop6h 25m

Punta Cana

Fri 3/5

2:30 pm-9:35 am

2 stops20h 05m

$469

Myrtle BeachSanto Domingo

MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas

MYRSDQ

Myrtle Beach Intl

Mon 1/18

5:06 pm-9:58 am

2 stops15h 52m

Santo Domingo Las Americas

Mon 1/25

2:43 pm-10:39 am

1 stop20h 56m

$583

Myrtle BeachPunta Cana

MYR Myrtle Beach Intl - PUJ Punta Cana

MYRPUJ

Myrtle Beach Intl

Mon 10/26

8:00 pm-12:39 pm

2 stops16h 39m

Punta Cana

Mon 11/2

4:51 pm-9:21 am

2 stops17h 30m

$682

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/4

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Best time to book a flight from Myrtle Beach to Dominican Republic

Have a flexible travel schedule? Discover the best time to fly to Dominican Republic from Myrtle Beach with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to the Dominican Republic

What is the cheapest month to book a flight from Myrtle Beach to Dominican Republic?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Dominican Republic (average of $553). Flying from Myrtle Beach to Dominican Republic in June is currently the most expensive (average of $906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Dominican Republic

See what other customers who have flown with Southwest and American Airlines from Myrtle Beach to the Dominican Republic have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

Courtney,Sep 2026

DEN - STL

I still think the aircraft should load from the back and window seats first for all passengers. It's so much easier and efficient to board when you do not have to worry about hitting Anyone already seated.

Related info for your journey

  • What airport do you fly from for flights from Myrtle Beach to Dominican Republic?

    Myrtle Beach Intl (MYR) is the airport you will fly out of if you book a flight from Myrtle Beach to Dominican Republic. It is only a 2.1 mi journey to Myrtle Beach Intl (MYR) from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Dominican Republic?

    There are many flights that can get you from Myrtle Beach to Dominican Republic in 6h 25m. Fly via Southwest, American Airlines, or Delta to get the fastest option. There are 1230 mi between Myrtle Beach and Dominican Republic. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Dominican Republic?

  • Can I find deals for flights from Myrtle Beach to Dominican Republic that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Dominican Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Dominican Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Dominican Republic.

  • Can I find deals for business class flights from Myrtle Beach to Dominican Republic?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Dominican Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Dominican Republic?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Dominican Republic (average of $553). Flying from Myrtle Beach to Dominican Republic in June is currently the most expensive (average of $906). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Myrtle Beach to Dominican Republic

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$498Average$730FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$667Average$826FlexibilityNo cancel feeOn-time63%

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