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Santo Domingo

$318+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDQ
Aug 25 — Sep 11
Tue 8/25
Tue 9/1
1 adult, Economy
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Find cheap flights from Greenville to Santo Domingo with Cheapflights

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Cheap flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.

This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
GSP
-
SDQ
1 stop6h 27m
Delta
Wed 9/232:53 pm
SDQ
-
GSP
1 stop8h 02m
Delta
Deal found 7/24$550
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am
GSP
-
SDQ
2 stops12h 53m
American Airlines
Wed 11/256:00 am
SDQ
-
GSP
2 stops14h 54m
American Airlines
Deal found 7/22$560
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:19 pm
GSP
-
SDQ
2 stops16h 06m
American Airlines
Thu 8/272:22 pm
SDQ
-
GSP
2 stops8h 28m
American Airlines
Deal found 7/21$565
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:26 am
GSP
-
SDQ
1 stop12h 24m
American Airlines
Wed 1/276:29 pm
SDQ
-
GSP
1 stop24h 56m
American Airlines
Deal found 7/23$567
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:05 am
GSP
-
SDQ
1 stop5h 22m
Delta
Thu 9/242:53 pm
SDQ
-
GSP
1 stop6h 57m
Delta
Deal found 7/24$570
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:20 pm
GSP
-
SDQ
2 stops19h 19m
Delta
Tue 9/152:53 pm
SDQ
-
GSP
1 stop8h 02m
Delta
Deal found 7/25$575
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 pm
GSP
-
SDQ
1 stop18h 42m
American Airlines
Mon 8/317:00 am
SDQ
-
GSP
1 stop15h 58m
American Airlines
Deal found 7/25$580
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:05 am
GSP
-
SDQ
1 stop5h 22m
Delta
Mon 10/122:57 pm
SDQ
-
GSP
1 stop6h 54m
Delta
Deal found 7/25$590

Find flight deals from Greenville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$550
(Delta)

One-way from

$318
(Delta)

Popular in

December

Cheapest in

September

Average price

$815
Provider with most accurate pricing for Greenville-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santo Domingo Las Americas flights.
Search Deals
From Greenville to Santo Domingo Las Americas
Search Deals
One-way flight from Greenville to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/18

6:45 am-2:40 pm

1 stop6h 55m

Santo Domingo Las Americas

Wed 11/25

3:55 pm-9:21 pm

1 stop6h 26m

$550

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 9/16

5:45 am-6:07 pm

2 stops12h 22m

Santo Domingo Las Americas

Fri 9/25

7:35 pm-12:50 pm

2 stops17h 15m

$555

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 9/8

5:45 am-6:07 pm

2 stops12h 22m

Santo Domingo Las Americas

Wed 9/16

7:35 pm-12:50 pm

2 stops17h 15m

$555

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 10/20

7:45 am-1:41 pm

1 stop5h 56m

Santo Domingo Las Americas

Wed 11/18

6:45 am-5:41 pm

2 stops11h 56m

$555

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 8/20

6:00 am-3:24 pm

1 stop9h 24m

Santo Domingo Las Americas

Thu 8/27

4:24 pm-6:10 pm

1 stop25h 46m

$560

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 11/18

6:00 am-7:53 pm

2 stops12h 53m

Santo Domingo Las Americas

Wed 11/25

6:00 am-7:54 pm

2 stops14h 54m

$560
Cheapest one-way

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 8/24

6:55 am-6:06 pm

2 stops11h 11m

$318

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 12/10

6:30 am-5:23 pm

2 stops9h 53m

$324
Quickest one-way

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 8/4

6:55 am-1:28 pm

1 stop6h 33m

$393

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 8/4

6:35 am-6:40 pm

2 stops12h 05m

$401

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/25

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Greenville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in July.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Currently, September is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $514). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $982). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Santo Domingo?

Airfare is below average for this route at the moment.

Greenville to Santo Domingo flights typically cost between $738 and $919 in September.
The cheapest round-trip price found within the last 5 days was $550 on Delta (Sep 16-Sep 22).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 26, 2026.
Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,492 reviews

Food

7.2

Entertainment

7.8

Overall

7.8

Comfort

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,492 reviews
Delta
7.8
Good
8,492 reviews

Food

7.2

Entertainment

7.8

Overall

7.8

Comfort

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,851 reviews
Delta
7.8
Good
8,492 reviews

Food

7.2

Entertainment

7.8

Overall

7.8

Comfort

7.8

Crew

8.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santo Domingo?

    Airlines like Delta fly from Greenville to Santo Domingo in about 6h 40m. The time it takes to get you to your destination can typically vary by up to . There are 1373 mi between Greenville and Santo Domingo.

  • What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

    Our cheapest airline available from Greenville to Santo Domingo is American Airlines. Our recent data shows that you can find tickets from as low as $488 on this airline. An additional option worth looking into is Delta, starting at $499. American Airlines is priced at 27% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.

  • Can I find deals for business class flights from Greenville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santo Domingo?

    Currently, September is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $514). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $982). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Greenville to Santo Domingo

Discover the top 2 airlines that operate flights from Greenville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$488Average$585FlexibilityNo cancel feeOn-time71%
DeltaCheapest$499Average$517FlexibilityNo cancel feeOn-timeN/A

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