$318+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDQ
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Santo Domingo
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One-way
Cheapest flights from Greenville to Santo DomingoExplore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop8h 10m
Mon 10/126:00 am -
1 stop17h 13m
Deal found 9/7![United Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
2 stops14h 45m
Thu 10/2910:27 am -
2 stops12h 51m
Deal found 9/7![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:53 am -
2 stops12h 00m
Wed 11/256:00 am -
2 stops16h 27m
Deal found 9/10![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:08 pm -
1 stop13h 14m
Mon 10/124:20 pm -
1 stop6h 32m
Deal found 9/7![American Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:33 pm -
2 stops17h 00m
Tue 10/137:00 am -
2 stops15h 56m
Deal found 9/7![American Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
1 stop9h 20m
Tue 10/137:00 am -
1 stop15h 52m
Deal found 9/9![American Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:05 am -
1 stop6h 27m
Wed 11/254:06 pm -
1 stop8h 32m
Deal found 9/8![Delta logo]()
$630
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:57 pm -
2 stops17h 25m
Thu 10/227:00 am -
2 stops10h 22m
Deal found 9/9![American Airlines logo]()
$640
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:40 am -
2 stops12h 26m
Tue 10/137:35 pm -
2 stops15h 25m
Deal found 9/9![Delta logo]()
$645
Best flights from Greenville to Santo DomingoDiscover carefully curated flight deals from Greenville to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Greenville to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:00 am -
1 stop6h 32m
Thu 10/222:57 pm -
1 stop7h 54m
Deal found 9/9![Delta logo]()
$550
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop8h 10m
Mon 10/126:00 am -
1 stop17h 13m
Deal found 9/7![United Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
2 stops14h 45m
Thu 10/2910:27 am -
2 stops12h 51m
Deal found 9/7![American Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:00 am -
2 stops12h 20m
Wed 2/37:30 am -
2 stops11h 11m
Deal found 9/9![Delta logo]()
$555
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:53 am -
2 stops12h 00m
Wed 11/256:00 am -
2 stops16h 27m
Deal found 9/10![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:41 pm -
2 stops15h 18m
Thu 11/511:09 am -
1 stop9h 33m
Deal found 9/9![American Airlines logo]()
$655
Last-minute flights from Greenville to Santo DomingoDiscover last-minute flight deals from Greenville to Santo Domingo. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Santo Domingo. Data last updated September 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop8h 10m
Mon 10/126:00 am -
1 stop17h 13m
Deal found 9/7![United Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:08 pm -
1 stop13h 14m
Mon 10/124:20 pm -
1 stop6h 32m
Deal found 9/7![American Airlines logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
1 stop9h 20m
Tue 10/137:00 am -
1 stop15h 52m
Deal found 9/9![American Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:40 am -
2 stops12h 26m
Tue 10/137:35 pm -
2 stops15h 25m
Deal found 9/9![Delta logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:33 pm -
2 stops17h 00m
Tue 10/137:00 am -
2 stops15h 56m
Deal found 9/7![American Airlines logo]()
$614
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:57 pm -
2 stops17h 25m
Thu 10/227:00 am -
2 stops10h 22m
Deal found 9/9![American Airlines logo]()
$640
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am -
1 stop16h 46m
Thu 10/223:20 pm -
1 stop7h 53m
Deal found 9/9![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
2 stops14h 45m
Thu 10/297:00 am -
1 stop15h 52m
Deal found 9/7![American Airlines logo]()
$555
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:50 am -
1 stop8h 16m
Fri 10/301:53 pm -
1 stop9h 07m
Deal found 9/9![United Airlines logo]()
$770
One-way flights from Greenville to Santo DomingoSearch for one-way flight options from Greenville to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Greenville to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:00 am -
1 stop16h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/710:12 am -
3 stops25h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$613
Find flight deals from Greenville to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $550 (United Airlines) |
One-way from | $318 (United Airlines) |
Popular in | December |
Cheapest in | November |
Average price | $540 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Thu 1/7
10:29 am-9:42 pm
2 stops10h 13m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$318
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Thu 1/7
6:00 am-11:46 pm
1 stop16h 46m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$318
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Wed 10/14
7:00 am-1:32 pm
1 stop6h 32m
Santo Domingo Las Americas
Thu 10/22
2:57 pm-10:51 pm
1 stop7h 54m
$550
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Mon 10/5
6:00 am-2:10 pm
1 stop8h 10m
Santo Domingo Las Americas
Mon 10/12
6:00 am-11:13 pm
1 stop17h 13m
$550
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Thu 10/22
6:05 am-8:50 pm
2 stops14h 45m
Santo Domingo Las Americas
Thu 10/29
10:27 am-11:18 pm
2 stops12h 51m
$555
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Wed 1/13
6:00 am-7:20 pm
2 stops12h 20m
Santo Domingo Las Americas
Wed 2/3
7:30 am-5:41 pm
2 stops11h 11m
$555
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Wed 11/18
6:53 am-7:53 pm
2 stops12h 00m
Santo Domingo Las Americas
Wed 11/25
6:00 am-9:27 pm
2 stops16h 27m
$560
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Thu 1/7
10:12 am-1:08 pm
3 stops25h 56m
Santo Domingo Las Americas
Wed 12/31
12:00 am-11:30 pm
Nonstop0h 00m
$613
GreenvilleSanto Domingo
GSP Greenville - SDQ Santo Domingo Las Americas
GSPSDQ
Greenville
Mon 11/2
7:41 pm-11:59 am
2 stops15h 18m
Santo Domingo Las Americas
Thu 11/5
11:09 am-7:42 pm
1 stop9h 33m
$655
Sorted by cheapest first
Compare providers for flights from Greenville to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.
GSP-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Santo Domingo
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 12, 2026.
Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
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Greenville and Santo Domingo flights
Browse other Greenville and Santo Domingo flight options. Last updated on September 12, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Top 3 airlines flying from Greenville to Santo Domingo
Discover the top 3 airlines that operate flights from Greenville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$488 | Average$595 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$499 | Average$528 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$514 | Average$700 | FlexibilityNo cancel fee | On-time69% |