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Santo Domingo

$252+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDQ
Jul 11 — Jul 181
Sat 7/11
Sat 7/18
1 adult, Economy
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Cheap flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.

This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
GSP
-
SDQ
2 stops12h 40m
American Airlines
Tue 7/147:00 am
SDQ
-
GSP
1 stop12h 30m
American Airlines
Deal found 6/8$545
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
GSP
-
SDQ
1 stop22h 40m
American Airlines
Wed 7/1510:27 am
SDQ
-
GSP
1 stop13h 29m
American Airlines
Deal found 6/8$549
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:00 pm
GSP
-
SDQ
1 stop13h 27m
American Airlines
Fri 7/107:00 am
SDQ
-
GSP
1 stop12h 30m
American Airlines
Deal found 6/7$615
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:00 pm
GSP
-
SDQ
1 stop13h 27m
American Airlines
Sun 7/124:24 pm
SDQ
-
GSP
1 stop7h 32m
American Airlines
Deal found 6/8$625
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:00 pm
GSP
-
SDQ
1 stop13h 27m
American Airlines
Mon 8/31:57 pm
SDQ
-
GSP
1 stop20h 53m
American Airlines
Deal found 6/8$630
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:15 pm
GSP
-
SDQ
1 stop13h 09m
American Airlines
Mon 7/610:27 am
SDQ
-
GSP
1 stop13h 29m
American Airlines
Deal found 6/8$665
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:52 am
GSP
-
SDQ
2 stops13h 33m
American Airlines
Mon 7/610:27 am
SDQ
-
GSP
1 stop13h 29m
American Airlines
Deal found 6/10$689
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:09 pm
GSP
-
SDQ
1 stop15h 18m
American Airlines
Sat 8/810:27 am
SDQ
-
GSP
1 stop12h 31m
American Airlines
Deal found 6/9$690

Find flight deals from Greenville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$545
(American Airlines)

One-way from

$252
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$722
Provider with most accurate pricing for Greenville-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santo Domingo Las Americas flights.
Search Deals
From Greenville to Santo Domingo Las Americas
Search Deals
One-way flight from Greenville to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Tue 7/7

8:00 pm-9:27 am

1 stop13h 27m

Santo Domingo Las Americas

Tue 7/14

7:00 am-7:30 pm

1 stop12h 30m

$579

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 7/6

8:00 pm-9:27 am

1 stop13h 27m

Santo Domingo Las Americas

Sun 7/12

4:24 pm-11:56 pm

1 stop7h 32m

$625

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 7/27

8:00 pm-9:27 am

1 stop13h 27m

Santo Domingo Las Americas

Mon 8/3

1:57 pm-10:50 am

1 stop20h 53m

$630

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 6/26

8:15 pm-9:24 am

1 stop13h 09m

Santo Domingo Las Americas

Mon 7/6

10:27 am-11:56 pm

1 stop13h 29m

$665

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 7/3

7:52 am-9:25 pm

2 stops13h 33m

Santo Domingo Las Americas

Mon 7/6

10:27 am-11:56 pm

1 stop13h 29m

$689

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 8/1

6:09 pm-9:27 am

1 stop15h 18m

Santo Domingo Las Americas

Sat 8/8

10:27 am-10:58 pm

1 stop12h 31m

$690
Quickest round-trip

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 10/14

6:00 am-2:10 pm

1 stop8h 10m

Santo Domingo Las Americas

Thu 10/22

3:20 pm-10:59 pm

1 stop7h 39m

$720

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Fri 7/3

6:00 am-6:40 pm

1 stop12h 40m

Santo Domingo Las Americas

Sun 7/5

7:00 am-11:56 pm

1 stop16h 56m

$741

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 11/9

6:00 am-11:46 pm

1 stop16h 46m

Santo Domingo Las Americas

Thu 11/12

4:18 pm-11:19 pm

1 stop8h 01m

$755
Cheapest one-way

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 7/27

8:13 pm-11:03 am

2 stops38h 50m

$252

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/8

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Greenville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $434). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated June 11, 2026.
Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,399 reviews

Food

7.2

Comfort

7.8

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.9
Good
8,399 reviews
Delta
7.9
Good
8,399 reviews

Food

7.2

Comfort

7.8

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,640 reviews
Delta
7.9
Good
8,399 reviews

Food

7.2

Comfort

7.8

Entertainment

7.8

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santo Domingo?

    Airlines like American Airlines fly from Greenville to Santo Domingo in about 12h 40m. The time it takes to get you to your destination can typically vary by up to . There are 1373 mi between Greenville and Santo Domingo.

  • What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

    Our cheapest airline available from Greenville to Santo Domingo is American Airlines. Our recent data shows that you can find tickets from as low as $488 on this airline. An additional option worth looking into is Delta, starting at $499. American Airlines is priced at 19% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.

  • Can I find deals for business class flights from Greenville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $434). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $972). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Greenville to Santo Domingo

Discover the top 2 airlines that operate flights from Greenville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$488Average$567FlexibilityNo cancel feeOn-time71%
DeltaCheapest$499Average$517FlexibilityNo cancel feeOn-timeN/A

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