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$200+ Cheap flights from Santo Domingo (SDQ) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — MEX
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Find cheap flights from Santo Domingo to Mexico City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Mexico City Benito Juarez are usually found in October or September, booked 83 days in advance, depart on a Friday or Thursday and return on a Tuesday

Cheap flight deals from Santo Domingo to Mexico City

Cheapest flights from Santo Domingo to Mexico City
Explore the most affordable flight options available from Santo Domingo to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:45 am
SDQ
-
MEX
1 stop17h 30m
Copa Airlines
Wed 5/205:50 am
MEX
-
SDQ
1 stop8h 25m
Copa Airlines
Deal found 4/20$414
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:38 pm
SDQ
-
MEX
1 stop13h 37m
Multiple Airlines
Tue 5/511:05 am
MEX
-
SDQ
2 stops27h 24m
Multiple Airlines
Deal found 4/20$420
This SmartFares deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:01 am
SDQ
-
MEX
Nonstop4h 44m
Aeromexico
Thu 10/1512:15 am
MEX
-
SDQ
Nonstop4h 30m
Aeromexico
Deal found 4/20$429
This Super.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:45 pm
SDQ
-
MEX
1 stop16h 20m
Avianca
Thu 10/2212:40 am
MEX
-
SDQ
1 stop9h 10m
Avianca
Deal found 4/20$430
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:45 am
SDQ
-
MEX
1 stop15h 20m
Copa Airlines
Tue 5/55:50 am
MEX
-
SDQ
1 stop15h 06m
Copa Airlines
Deal found 4/21$436
This Copa Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:40 pm
SDQ
-
MEX
1 stop11h 25m
Copa Airlines
Sun 5/311:20 am
MEX
-
SDQ
1 stop9h 53m
Copa Airlines
Deal found 4/20$437
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:01 am
SDQ
-
MEX
Nonstop4h 54m
Aeromexico
Tue 11/101:05 am
MEX
-
SDQ
Nonstop4h 13m
Aeromexico
Deal found 4/23$439
This SmartFares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:37 am
SDQ
-
MEX
Nonstop4h 48m
Aeromexico
Sun 6/1412:15 am
MEX
-
SDQ
Nonstop4h 21m
Aeromexico
Deal found 4/24$441
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:08 pm
SDQ
-
MEX
1 stop8h 57m
Copa Airlines
Tue 5/53:30 pm
MEX
-
SDQ
1 stop22h 45m
Copa Airlines
Deal found 4/20$442
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:01 am
SDQ
-
MEX
Nonstop4h 34m
Aeromexico
Thu 7/912:15 am
MEX
-
SDQ
Nonstop4h 29m
Aeromexico
Deal found 4/21$444
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:45 pm
SDQ
-
MEX
1 stop16h 20m
Avianca
Mon 6/112:40 am
MEX
-
SDQ
1 stop9h 10m
Avianca
Deal found 4/22$445
This Aeromexico deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2911:01 am
SDQ
-
MEX
Nonstop4h 34m
Aeromexico
Tue 7/712:15 am
MEX
-
SDQ
Nonstop4h 29m
Aeromexico
Deal found 4/21$446

Find flight deals from Santo Domingo to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$414
(Copa Airlines)

One-way from

$200
(Mytrip)

Popular in

April

Cheapest in

October

Average price

$441

Good round-trip deal

$445 or less

Good one-way deal

$235 or less
Provider with most accurate pricing for Santo Domingo Las Americas-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Mexico City Benito Juarez flights.
Search Deals
From Santo Domingo Las Americas to Mexico City Benito Juarez
Search Deals
One-way flight from Santo Domingo Las Americas to Mexico City Benito Juarez
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Santo Domingo Las Americas to Mexico City Benito Juarez.
Search Deals
Price to beat on a one-way flight from Santo Domingo Las Americas to Mexico City Benito Juarez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Santo Domingo to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 5/13

8:45 am-12:15 am

1 stop17h 30m

Mexico City Benito Juarez

Wed 5/20

5:50 am-4:15 pm

1 stop8h 25m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 5/20

8:45 am-1:00 am

1 stop18h 15m

Mexico City Benito Juarez

Fri 5/22

1:20 am-10:55 am

1 stop7h 35m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Mon 5/18

12:10 pm-12:15 am

1 stop14h 05m

Mexico City Benito Juarez

Sun 5/24

1:20 am-1:13 pm

1 stop9h 53m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 5/12

8:45 am-10:05 pm

1 stop15h 20m

Mexico City Benito Juarez

Mon 5/18

1:20 am-4:15 pm

1 stop12h 55m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Thu 5/14

6:04 am-10:05 pm

1 stop18h 01m

Mexico City Benito Juarez

Thu 5/21

1:10 pm-10:56 pm

1 stop7h 46m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Thu 5/21

6:04 am-7:05 pm

1 stop15h 01m

Mexico City Benito Juarez

Tue 5/26

1:10 pm-10:56 pm

1 stop7h 46m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 5/19

12:40 pm-12:15 am

1 stop13h 35m

Mexico City Benito Juarez

Thu 5/21

5:50 am-4:15 pm

1 stop8h 25m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Fri 5/8

12:40 pm-1:00 am

1 stop14h 20m

Mexico City Benito Juarez

Sun 5/17

2:10 am-10:55 am

1 stop6h 45m

$414
Quickest round-trip

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Tue 5/19

12:40 pm-10:05 pm

1 stop11h 25m

Mexico City Benito Juarez

Fri 5/22

1:20 am-10:55 am

1 stop7h 35m

$414

Santo DomingoMexico City

SDQ - MEX

SDQMEX

Santo Domingo Las Americas

Wed 5/6

8:45 am-12:15 am

1 stop17h 30m

Mexico City Benito Juarez

Tue 5/12

1:10 pm-10:56 pm

1 stop7h 46m

$414

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/20

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Santo Domingo to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santo Domingo to Mexico City in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
SmartFaresPrice Accuracy1 starTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santo Domingo-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Mexico City

How far ahead should I book a flight from Santo Domingo to Mexico City?

The price you pay for your flight from Santo Domingo to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 82 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santo Domingo to Mexico City?

Currently, October is the cheapest month in which you can book a flight from Santo Domingo to Mexico City (average of $347). Flying from Santo Domingo to Mexico City in April is currently the most expensive (average of $441). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MEX?

Find hourly flight availability from Santo Domingo to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santo Domingo to Mexico City as you normally would.

How much does it cost to fly round-trip from Santo Domingo to Mexico City?

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown Copa Airlines and Aeromexico from Santo Domingo to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,577 reviews

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,577 reviews
Copa Airlines
7.5
Good
1,577 reviews

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Aeromexico
7.4
Good
1,541 reviews
Copa Airlines
7.5
Good
1,577 reviews

Crew

8.1

Entertainment

6.8

Comfort

7.4

Food

6.8

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Santo Domingo to Mexico City?

    Mexico City Benito Juarez is the airport most travelers will use when flying to Mexico City from Santo Domingo Las Americas. Booking flights from Las Americas (SDQ) to Benito Juarez (MEX) should be relatively easy as there is 1 daily flight to Mexico City from 3 different airlines. 4h 35m is how long a flight from Santo Domingo to Mexico City Benito Juarez will take if you book a nonstop flight.

  • How popular is this Santo Domingo to Mexico City flight route?

    Within the past month, 1 users have taken a look at flights from Santo Domingo Las Americas to Mexico City Benito Juarez.

  • How long is the flight from Santo Domingo to Mexico City?

    There are many flights that can get you from Santo Domingo to Mexico City in 17h 30m. Fly via Copa Airlines to get the fastest option. Airlines will cover a distance of 1919 mi.

  • What are the cheapest airlines flying from Santo Domingo to Mexico City round-trip?

    Currently priced at $152, Arajet will fly you from Santo Domingo to Mexico City and back. In addition to Arajet, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Copa Airlines and Aeromexico - these airlines can fly you to your destination from $166 and $204, respectively. These flights start at 62% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Santo Domingo to Mexico City one-way?

    To fly one-way, consider booking your trip with Arajet, which is currently one of the cheapest options available, starting at $145. Copa Airlines flights start at $187 while deals on Aeromexico start at $331 one-way.

  • What are the cheapest flights from Santo Domingo to Mexico City?

    Looking at all options, your cheapest flight can be booked for $405. While the most popular route (Santo Domingo Las Americas - Mexico City Benito Juarez) can be booked for $304 on average, our data indicates $605 when flying from Santo Domingo to Mexico City.

  • Can I find deals for flights from Santo Domingo to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Mexico City.

  • Can I find deals for business class flights from Santo Domingo to Mexico City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Mexico City?

    Currently, October is the cheapest month in which you can book a flight from Santo Domingo to Mexico City (average of $347). Flying from Santo Domingo to Mexico City in April is currently the most expensive (average of $441). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
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Alternative routes for Santo Domingo to Mexico City

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Santiago de los Caballeros to Mexico City flights

Top 3 airlines flying from Santo Domingo to Mexico City

Discover the top 3 airlines that operate flights from Santo Domingo to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$152Average$352FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$166Average$440FlexibilityNo cancel feeOn-time70%
AeromexicoCheapest$204Average$440FlexibilityNo cancel feeOn-timeN/A

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