South Carolina

$51+ Cheap flights from Louisville (SDF) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
Jan 22 — Jan 291
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to South Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Louisville to South Carolina

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to South Carolina (USSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 17, 2025.

Round-trip from

$89
(Priceline)

One-way from

$51
(Booking.com)
From Louisville Intl to South Carolina
One-way flight from Louisville Intl to South Carolina

Find flight deals from Louisville to South Carolina

Cheapest flights from Louisville to South Carolina
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 17, 2025.

This Priceline deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/228:26 amSDF - MYR
Nonstop1h 24mSpirit Airlines
Mon 3/243:40 pmMYR - SDF
Nonstop2h 00mSpirit Airlines
Deal found 1/16$89
This Booking.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/68:19 pmSDF - SAV
Nonstop1h 31mAllegiant Air
Mon 6/912:02 pmSAV - SDF
Nonstop1h 37mAllegiant Air
Deal found 1/15$102
This FlightHub deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/27:25 pmSDF - CHS
1 stop25h 25mSpirit Airlines
Fri 2/77:15 amCHS - SDF
1 stop11h 15mSpirit Airlines
Deal found 1/15$157
This CheapOair deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/219:30 pmSDF - CLT
1 stop26h 11mSpirit Airlines
Sun 2/238:52 pmCLT - SDF
1 stop23h 33mSpirit Airlines
Deal found 1/16$161
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/27:25 pmSDF - CHS
3 stops20h 46mMultiple Airlines
Fri 2/77:15 amCHS - SDF
1 stop11h 15mMultiple Airlines
Deal found 1/15$206
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/156:04 amSDF - CAE
1 stop3h 50mAmerican Airlines
Wed 3/198:05 pmCAE - SDF
1 stop4h 29mAmerican Airlines
Deal found 1/16$229
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/73:08 pmSDF - SAV
1 stop7h 40mMultiple Airlines
Mon 2/1011:42 amSAV - SDF
1 stop6h 48mMultiple Airlines
Deal found 1/15$238
This Mytrip deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/75:34 pmSDF - CLT
1 stop5h 54mMultiple Airlines
Mon 2/106:10 amCLT - SDF
1 stop12h 20mMultiple Airlines
Deal found 1/16$245
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/266:05 amSDF - SAV
1 stop6h 10mDelta
Tue 3/46:45 amSAV - SDF
1 stop5h 06mDelta
Deal found 1/16$247
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2612:36 pmSDF - SAV
2 stops6h 46mAmerican Airlines
Tue 3/46:30 amSAV - SDF
1 stop4h 59mAmerican Airlines
Deal found 1/16$252
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/136:17 amSDF - AGS
1 stop4h 29mAmerican Airlines
Sun 2/166:27 pmAGS - SDF
1 stop6h 11mAmerican Airlines
Deal found 1/16$257
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:00 amSDF - HHH
1 stop5h 15mAmerican Airlines
Mon 3/105:59 pmHHH - SDF
1 stop6h 35mAmerican Airlines
Deal found 1/16$259

Find flights from Louisville to South Carolina within your budget

Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Sat 3/22

8:26 am-9:50 am

Nonstop1h 24m

Myrtle Beach Intl

Mon 3/24

3:40 pm-5:40 pm

Nonstop2h 00m

$89

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Fri 6/6

8:19 pm-9:50 pm

Nonstop1h 31m

Savannah/Hilton Head

Mon 6/9

12:02 pm-1:39 pm

Nonstop1h 37m

$102

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Sun 2/2

7:25 pm-8:50 pm

1 stop25h 25m

Charleston

Fri 2/7

7:15 am-6:30 pm

1 stop11h 15m

$157

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Fri 2/21

9:30 pm-11:41 pm

1 stop26h 11m

Charlotte Douglas

Sun 2/23

8:52 pm-8:25 pm

1 stop23h 33m

$161

LouisvilleCharleston

SDF - CHS

SDFCHS

Louisville Intl

Sun 2/2

7:25 pm-4:11 pm

3 stops20h 46m

Charleston

Fri 2/7

7:15 am-6:30 pm

1 stop11h 15m

$206

LouisvilleColumbia

SDF - CAE

SDFCAE

Louisville Intl

Sat 3/15

6:04 am-9:54 am

1 stop3h 50m

Columbia Metropolitan

Wed 3/19

8:05 pm-12:34 am

1 stop4h 29m

$229

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Fri 2/7

3:08 pm-10:48 pm

1 stop7h 40m

Savannah/Hilton Head

Mon 2/10

11:42 am-6:30 pm

1 stop6h 48m

$238

LouisvilleCharlotte

SDF - CLT

SDFCLT

Louisville Intl

Fri 2/7

5:34 pm-11:28 pm

1 stop5h 54m

Charlotte Douglas

Mon 2/10

6:10 am-6:30 pm

1 stop12h 20m

$245

LouisvilleMyrtle Beach

SDF - MYR

SDFMYR

Louisville Intl

Wed 1/29

6:00 am-1:03 pm

1 stop7h 03m

Myrtle Beach Intl

Sat 2/1

1:54 pm-10:29 pm

1 stop8h 35m

$247

LouisvilleSavannah

SDF - SAV

SDFSAV

Louisville Intl

Wed 2/26

6:05 am-12:15 pm

1 stop6h 10m

Savannah/Hilton Head

Tue 3/4

6:45 am-11:51 am

1 stop5h 06m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 54 results
1
2
3
...
6

Best time to book a flight from Louisville to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Louisville to South Carolina

Get recent, data-driven insights about flights from Louisville to South Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Louisville to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $217). Flying from Louisville to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to SC?

Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Louisville to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 17, 2025.
Get a feel of what it's like to fly with Spirit Airlines, American Airlines and Southwest from Louisville to South Carolina by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.