$54+ Cheap flights from Louisville (SDF) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CHS
May 29 — Jun 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Louisville to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Louisville to South CarolinaExplore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Louisville to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 7/99:00 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 4/28![Allegiant Air logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/2511:20 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 4/25![Allegiant Air logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:56 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/215:10 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/288:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 4/25![Allegiant Air logo]()
$103
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 8/37:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$107
This Breeze Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 8/177:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 7/317:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/25![Breeze Airways logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/264:52 pm
SDF
- SAV
Nonstop1h 34m
Allegiant Air
Sun 8/28:45 am
SAV
- SDF
Nonstop1h 38m
Allegiant Air
Deal found 4/25![Allegiant Air logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/48:56 pm
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Sun 6/712:30 pm
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$124
This Booking.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:14 am
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Thu 6/188:45 am
SAV
- SDF
Nonstop1h 39m
Allegiant Air
Deal found 4/27![Allegiant Air logo]()
$125
This Breeze Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:59 pm
SDF
- CHS
Nonstop1h 35m
Breeze Airways
Mon 10/56:10 am
CHS
- SDF
Nonstop1h 52m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 6/127:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$133
Best flights from Louisville to South CarolinaDiscover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Louisville to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:45 pm
SDF
- CHS
1 stop5h 41m
Delta
Fri 7/315:10 am
CHS
- SDF
1 stop5h 19m
Delta
Deal found 4/27![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
SDF
- MYR
1 stop3h 59m
United Airlines
Wed 6/103:08 pm
MYR
- SDF
1 stop7h 22m
United Airlines
Deal found 4/25![United Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:00 am
SDF
- MYR
2 stops8h 25m
Southwest
Sat 5/2311:50 am
MYR
- SDF
2 stops9h 00m
Southwest
Deal found 4/26![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:00 am
SDF
- HHH
1 stop6h 09m
American Airlines
Thu 9/32:48 pm
HHH
- SDF
1 stop4h 37m
American Airlines
Deal found 4/27![American Airlines logo]()
$341
This Breeze Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:23 am
SDF
- CHS
2 stops10h 35m
Breeze Airways
Mon 10/53:14 pm
CHS
- SDF
1 stop5h 28m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$347
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:00 am
SDF
- CHS
1 stop3h 42m
Delta
Mon 8/35:00 pm
CHS
- SDF
1 stop6h 18m
Delta
Deal found 4/27![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:10 am
SDF
- MYR
1 stop5h 08m
United Airlines
Sat 5/233:08 pm
MYR
- SDF
1 stop5h 15m
United Airlines
Deal found 4/26![United Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:47 pm
SDF
- CHS
1 stop5h 09m
Delta
Sat 5/234:55 pm
CHS
- SDF
1 stop4h 54m
Delta
Deal found 4/28![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
SDF
- CHS
1 stop4h 16m
United Airlines
Sat 5/306:00 am
CHS
- SDF
2 stops8h 37m
United Airlines
Deal found 4/27![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:00 am
SDF
- CLT
2 stops10h 45m
Southwest
Tue 6/21:45 pm
CLT
- SDF
2 stops7h 20m
Southwest
Deal found 4/27![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:00 am
SDF
- AGS
1 stop3h 29m
American Airlines
Tue 6/98:54 am
AGS
- SDF
2 stops8h 51m
American Airlines
Deal found 4/27![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:20 am
SDF
- MYR
2 stops7h 10m
Southwest
Wed 5/272:10 pm
MYR
- SDF
2 stops6h 55m
Southwest
Deal found 4/28![Southwest logo]()
$335
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:29 pm
SDF
- SAV
1 stop5h 31m
Delta
Tue 5/266:53 pm
SAV
- SDF
1 stop5h 32m
Delta
Deal found 4/27![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am
SDF
- SAV
1 stop4h 37m
United Airlines
Tue 10/611:26 am
SAV
- SDF
1 stop5h 23m
United Airlines
Deal found 4/29![United Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:30 pm
SDF
- CAE
1 stop4h 33m
United Airlines
Sat 5/162:20 pm
CAE
- SDF
1 stop5h 57m
United Airlines
Deal found 4/24![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:50 am
SDF
- GSP
1 stop4h 15m
Southwest
Sun 8/3010:45 am
GSP
- SDF
1 stop3h 25m
Southwest
Deal found 4/26![Southwest logo]()
$347
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:00 am
SDF
- HHH
1 stop5h 29m
Delta
Mon 7/2712:11 pm
HHH
- SDF
1 stop5h 38m
Delta
Deal found 4/26![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:43 am
SDF
- HHH
1 stop6h 51m
American Airlines
Mon 5/1811:03 am
HHH
- SDF
2 stops10h 27m
American Airlines
Deal found 4/29![American Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:40 am
SDF
- SAV
2 stops9h 20m
Southwest
Tue 5/268:05 am
SAV
- SDF
1 stop4h 35m
Southwest
Deal found 4/27![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
SDF
- SAV
1 stop3h 19m
Delta
Fri 6/263:53 pm
SAV
- SDF
1 stop3h 31m
Delta
Deal found 4/25![Delta logo]()
$326
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:06 am
SDF
- HHH
1 stop4h 36m
American Airlines
Sun 9/206:07 pm
HHH
- SDF
1 stop3h 32m
American Airlines
Deal found 4/28![American Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:05 am
SDF
- CAE
1 stop4h 05m
United Airlines
Tue 9/12:29 pm
CAE
- SDF
1 stop6h 07m
United Airlines
Deal found 4/25![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:45 am
SDF
- MYR
2 stops10h 25m
Southwest
Sat 6/132:00 pm
MYR
- SDF
2 stops7h 40m
Southwest
Deal found 4/29![Southwest logo]()
$361
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:05 am
SDF
- MYR
1 stop3h 39m
Delta
Mon 7/611:30 am
MYR
- SDF
1 stop5h 16m
Delta
Deal found 4/26![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/214:50 pm
SDF
- GSP
1 stop4h 58m
American Airlines
Thu 9/248:40 pm
GSP
- SDF
1 stop3h 27m
American Airlines
Deal found 4/25![American Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
SDF
- CAE
1 stop3h 56m
United Airlines
Sun 6/76:25 am
CAE
- SDF
1 stop7h 05m
United Airlines
Deal found 4/28![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:45 pm
SDF
- MYR
1 stop4h 05m
Southwest
Thu 6/42:00 pm
MYR
- SDF
2 stops8h 25m
Southwest
Deal found 4/28![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:55 pm
SDF
- SAV
1 stop7h 15m
United Airlines
Fri 10/96:30 pm
SAV
- SDF
1 stop5h 35m
United Airlines
Deal found 4/25![United Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:56 am
SDF
- AGS
2 stops9h 04m
American Airlines
Tue 5/196:20 am
AGS
- SDF
1 stop3h 35m
American Airlines
Deal found 4/26![American Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
SDF
- AGS
1 stop3h 18m
Delta
Tue 6/98:33 pm
AGS
- SDF
1 stop3h 59m
Delta
Deal found 4/27![Delta logo]()
$357
Last-minute flights from Louisville to South CarolinaDiscover last-minute flight deals from Louisville to South Carolina. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to South Carolina. Data last updated April 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 5/117:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/26![Breeze Airways logo]()
$142
This Super.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 5/157:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/24![Breeze Airways logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:33 am
SDF
- CLT
1 stop27h 38m
Multiple Airlines
Fri 5/156:00 am
CLT
- SDF
1 stop12h 58m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$192
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 5/187:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$168
This Breeze Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Thu 5/2110:58 am
CHS
- SDF
1 stop7h 17m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:33 am
SDF
- CLT
1 stop25h 01m
Multiple Airlines
Sun 5/176:41 pm
CLT
- SDF
1 stop14h 47m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$189
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:33 am
SDF
- CLT
1 stop25h 01m
Spirit Airlines
Sun 5/179:07 pm
CLT
- SDF
1 stop12h 21m
Spirit Airlines
Deal found 4/28![Spirit Airlines logo]()
$194
This Breeze Airways deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Fri 5/227:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:48 pm
SDF
- CLT
1 stop16h 17m
Multiple Airlines
Thu 5/219:07 pm
CLT
- SDF
1 stop12h 21m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$187
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Mon 6/17:00 am
CHS
- SDF
Nonstop1h 46m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:55 pm
SDF
- SAV
1 stop27h 40m
Multiple Airlines
Thu 6/412:30 pm
SAV
- SDF
Nonstop1h 39m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3110:33 am
SDF
- CLT
1 stop25h 32m
Multiple Airlines
Thu 6/46:41 pm
CLT
- SDF
1 stop16h 40m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$202
One-way flights from Louisville to South CarolinaSearch for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Louisville to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Booking.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 4/28![Breeze Airways logo]()
$54
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 4/29![Breeze Airways logo]()
$75
This Breeze Airways deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
SDF
- CHS
Nonstop1h 38m
Breeze Airways
Deal found 4/27![Breeze Airways logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:14 am
SDF
- SAV
Nonstop1h 31m
Allegiant Air
Deal found 4/25![Allegiant Air logo]()
$80
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:33 am
SDF
- CLT
1 stop13h 07m
Spirit Airlines
Deal found 4/26![Spirit Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/229:15 pm
SDF
- CLT
1 stop25h 57m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:33 am
SDF
- CLT
1 stop9h 29m
Spirit Airlines
Deal found 4/28![Spirit Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:33 am
SDF
- CLT
1 stop9h 29m
Spirit Airlines
Deal found 4/28![Spirit Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:20 pm
SDF
- CLT
1 stop11h 20m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:48 pm
SDF
- CLT
1 stop26h 24m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$118
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/153:29 pm
SDF
- CHS
1 stop6h 35m
Delta
Deal found 4/29![Delta logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:33 am
SDF
- CLT
1 stop25h 01m
Spirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$121
Find flight deals from Louisville to South Carolina
Keep the following information in mind while searching for Louisville to South Carolina flight deals. Data was last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $86 (Kiwi.com) |
One-way from | $54 (Booking.com) |
Popular in | January |
Cheapest in | July |
Average price | $387 |
Good round-trip deal | $143 or less |
Good one-way deal | $59 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Louisville to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 7/27
6:45 pm-12:26 am
1 stop5h 41m
Charleston
Fri 7/31
5:10 am-10:29 am
1 stop5h 19m
$237
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 7/27
10:00 am-1:42 pm
1 stop3h 42m
Charleston
Mon 8/3
5:00 pm-11:18 pm
1 stop6h 18m
$237
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Sat 6/6
6:00 am-9:59 am
1 stop3h 59m
Myrtle Beach Intl
Wed 6/10
3:08 pm-10:30 pm
1 stop7h 22m
$293
LouisvilleMyrtle Beach
SDF - MYR
SDFMYR
Louisville Intl
Tue 5/19
9:10 am-2:18 pm
1 stop5h 08m
Myrtle Beach Intl
Sat 5/23
3:08 pm-8:23 pm
1 stop5h 15m
$293
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Mon 5/18
5:47 pm-10:56 pm
1 stop5h 09m
Charleston
Sat 5/23
4:55 pm-9:49 pm
1 stop4h 54m
$294
LouisvilleCharleston
SDF - CHS
SDFCHS
Louisville Intl
Wed 5/27
6:00 am-10:16 am
1 stop4h 16m
Charleston
Sat 5/30
6:00 am-2:37 pm
2 stops8h 37m
$299
LouisvilleSavannah
SDF - SAV
SDFSAV
Louisville Intl
Sat 5/23
3:29 pm-9:00 pm
1 stop5h 31m
Savannah/Hilton Head
Tue 5/26
6:53 pm-12:25 am
1 stop5h 32m
$309
LouisvilleSavannah
SDF - SAV
SDFSAV
Louisville Intl
Tue 9/29
6:00 am-10:37 am
1 stop4h 37m
Savannah/Hilton Head
Tue 10/6
11:26 am-4:49 pm
1 stop5h 23m
$311
LouisvilleColumbia
SDF - CAE
SDFCAE
Louisville Intl
Sat 5/9
2:30 pm-7:03 pm
1 stop4h 33m
Columbia Metropolitan
Sat 5/16
2:20 pm-8:17 pm
1 stop5h 57m
$314
LouisvilleHilton Head Island
SDF - HHH
SDFHHH
Louisville Intl
Thu 7/23
10:00 am-3:29 pm
1 stop5h 29m
Hilton Head Island
Mon 7/27
12:11 pm-5:49 pm
1 stop5h 38m
$325
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Louisville to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Louisville with our price prediction graph.
SDF-CHS
SDF-MYR
SDF-CLT
SDF-SAV
SDF-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to South Carolina
SDF-USSC
SDF-CHS
SDF-MYR
SDF-CLT
SDF-SAV
How far ahead should I book a flight from Louisville to South Carolina?
To ensure you get the cheapest price possible for a flight from Louisville to South Carolina, you should look to book at least 40 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Louisville to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Louisville to South Carolina (average of $37). Flying from Louisville to South Carolina in March is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDF to SC?
Find hourly flight availability from Louisville to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.
A simple way to save on the total cost of your ticket is to fly from Louisville to South Carolina in the morning. If you’re flexible enough to do this you can expect to save up to 46% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Louisville to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 29, 2026.
Get a feel of what it's like to fly with Breeze Airways,Delta, andAllegiant Air from Louisville to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.6
Overall
8.1
Boarding
8.3
Crew
8.7
Food
6.6
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Louisville to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Louisville to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to South Carolina by cabin class
Find flights from Louisville to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and South Carolina flights
Browse other Louisville and South Carolina flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to South Carolina flights
Consider these flights traveling from Louisville to South Carolina.
Top 7 airlines flying from Louisville to South Carolina
Discover the top 7 airlines that operate flights from Louisville to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$63 | Average$188 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$69 | Average$148 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$77 | Average$129 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$340 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$148 | Average$468 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$183 | Average$341 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$219 | Average$385 | FlexibilityNo cancel fee | On-time63% |