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$40+ Cheap flights from South Carolina to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
May 2 — May 91
Sat 5/2
Sat 5/9
1 adult, Economy
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Cheap flight deals from South Carolina to Louisville

Cheapest flights from South Carolina to Louisville
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:00 am
SAV
-
SDF
Nonstop1h 38m
Allegiant Air
Sun 7/124:52 pm
SDF
-
SAV
Nonstop1h 34m
Allegiant Air
Deal found 3/30$99
This Booking.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:00 am
CHS
-
SDF
Nonstop1h 46m
Breeze Airways
Mon 7/278:28 pm
SDF
-
CHS
Nonstop1h 38m
Breeze Airways
Deal found 3/31$123
This Booking.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:00 am
CHS
-
SDF
Nonstop1h 46m
Breeze Airways
Mon 5/118:28 pm
SDF
-
CHS
Nonstop1h 38m
Breeze Airways
Deal found 3/30$144
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:39 am
MYR
-
SDF
Nonstop1h 37m
Allegiant Air
Sat 6/271:06 pm
SDF
-
MYR
Nonstop1h 32m
Allegiant Air
Deal found 3/30$166
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/99:00 am
SAV
-
SDF
Nonstop1h 38m
Multiple Airlines
Sun 7/126:55 pm
SDF
-
SAV
1 stop27h 32m
Multiple Airlines
Deal found 3/30$183
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2312:25 pm
MYR
-
SDF
1 stop23h 05m
Multiple Airlines
Sat 6/271:06 pm
SDF
-
MYR
Nonstop1h 32m
Multiple Airlines
Deal found 3/30$190
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:56 am
CLT
-
SDF
1 stop10h 02m
Multiple Airlines
Mon 5/47:48 pm
SDF
-
CLT
1 stop18h 23m
Multiple Airlines
Deal found 3/31$208
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:41 pm
CLT
-
SDF
1 stop24h 17m
Multiple Airlines
Mon 5/187:48 pm
SDF
-
CLT
1 stop16h 17m
Multiple Airlines
Deal found 4/1$210
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:38 pm
MYR
-
SDF
1 stop27h 37m
Multiple Airlines
Sat 6/271:06 pm
SDF
-
MYR
Nonstop1h 32m
Multiple Airlines
Deal found 3/30$212
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:54 pm
CLT
-
SDF
1 stop19h 10m
Multiple Airlines
Fri 4/247:48 pm
SDF
-
CLT
1 stop13h 22m
Multiple Airlines
Deal found 3/31$215
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:41 pm
CLT
-
SDF
1 stop16h 53m
Multiple Airlines
Fri 5/229:10 pm
SDF
-
CLT
1 stop14h 55m
Multiple Airlines
Deal found 3/28$216
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:41 pm
CLT
-
SDF
1 stop24h 17m
Multiple Airlines
Fri 5/1510:33 am
SDF
-
CLT
1 stop25h 32m
Multiple Airlines
Deal found 4/1$217

Find flight deals from South Carolina to Louisville

Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated April 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$99
(Kiwi.com)

One-way from

$40
(Kiwi.com)

Popular in

March

Cheapest in

May

Average price

$257

Good round-trip deal

$299 or less
Provider with most accurate pricing for Myrtle Beach Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Louisville Intl flights.
Search Deals
From South Carolina to Louisville Intl
Search Deals
One-way flight from South Carolina to Louisville Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from South Carolina to Louisville Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Fri 5/8

6:00 am-11:40 am

1 stop5h 40m

Louisville Intl

Mon 5/11

4:45 pm-9:30 pm

1 stop4h 45m

$237

ColumbiaLouisville

CAE - SDF

CAESDF

Columbia Metropolitan

Wed 5/6

4:01 pm-9:31 pm

1 stop5h 30m

Louisville Intl

Sat 5/9

5:47 pm-11:49 pm

1 stop6h 02m

$271

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Tue 5/26

6:00 pm-10:55 pm

1 stop4h 55m

Louisville Intl

Tue 6/2

10:30 am-8:00 pm

2 stops9h 30m

$280

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Wed 5/6

6:00 am-2:07 pm

2 stops8h 07m

Louisville Intl

Sat 5/9

5:50 am-10:13 am

1 stop4h 23m

$300

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Thu 4/30

11:52 am-5:04 pm

1 stop5h 12m

Louisville Intl

Sun 5/3

6:06 pm-11:29 pm

1 stop5h 23m

$306
Quickest round-trip

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 5/7

5:20 am-8:38 am

1 stop3h 18m

Louisville Intl

Mon 5/11

7:52 pm-11:57 pm

1 stop4h 05m

$311

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 4/23

6:25 am-11:40 am

1 stop5h 15m

Louisville Intl

Mon 4/27

5:25 pm-10:15 pm

1 stop4h 50m

$311

GreenvilleLouisville

GSP - SDF

GSPSDF

Greenville

Thu 5/28

6:25 am-11:40 am

1 stop5h 15m

Louisville Intl

Mon 6/1

4:45 pm-8:55 pm

1 stop4h 10m

$311

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Thu 5/14

6:10 am-11:40 am

1 stop5h 30m

Louisville Intl

Mon 5/18

4:45 pm-9:20 pm

1 stop4h 35m

$311

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Wed 5/13

11:30 am-2:45 pm

1 stop3h 15m

Louisville Intl

Fri 5/15

2:40 pm-9:50 pm

2 stops7h 10m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Louisville

What is the cheapest month to book a flight from South Carolina to Louisville?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDF?

Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2026.

It’s optimal to fly from South Carolina to Louisville at noon. By choosing this option you can save up to 69% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from South Carolina to Louisville?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from South Carolina?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from South Carolina to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How popular is this South Carolina to Louisville flight route?

    Within the past month, 1 users have taken a look at flights from South Carolina to Louisville Intl.

  • How long is the flight from South Carolina to Louisville?

    A quick flight from South Carolina to Louisville can take about 3h 18m. Southwest provides one of the quickest options available for as low as $311. The distance between South Carolina and Louisville is about 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Louisville one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $42. Users have also found prices from $55 and $88 on Breeze Airways and Delta, respectively.

  • What are the most popular routes from South Carolina to Louisville?

    Most travelers choose Charlotte Douglas - Louisville Intl, Charleston - Louisville Intl or Savannah/Hilton Head - Louisville Intl when deciding on the best route from South Carolina to Louisville.

  • What are the cheapest flights from South Carolina to Louisville?

    The cheapest flight price from South Carolina to Louisville is $299. On average you can expect to pay $306. The most popular route, (Charlotte Douglas - Louisville Intl), can usually be booked for $215.

  • Can I find deals for flights from South Carolina to Louisville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Louisville.

  • Can I find deals for business class flights from South Carolina to Louisville?

    Yes. Cheapflights offers flight deals from South Carolina to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Louisville?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $31). Flying from South Carolina to Louisville in January is currently the most expensive (average of $105). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Top 4 airlines flying from South Carolina to Louisville

Discover the top 4 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$31Average$107FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$49Average$132FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$125Average$356FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$320FlexibilityNo cancel feeOn-time71%

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