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$82+ Cheap flights from O'Hare Intl (ORD) to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/23. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheapflights Tip: The best prices from Chicago O'Hare Intl to Knoxville McGhee Tyson are usually found in August or February, booked 70 days in advance, depart on a Saturday or Wednesday and return on a Friday

Cheap flight deals from O'Hare Intl to Knoxville

Cheapest flights from O'Hare Intl to Knoxville
Explore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:50 pm
ORD
-
TYS
2 stops25h 50m
Multiple Airlines
Thu 6/49:20 pm
TYS
-
ORD
1 stop16h 04m
Multiple Airlines
Deal found 4/28$205
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 pm
ORD
-
TYS
1 stop15h 22m
Multiple Airlines
Wed 5/272:20 pm
TYS
-
ORD
1 stop9h 53m
Multiple Airlines
Deal found 4/27$211
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:52 am
ORD
-
TYS
1 stop30h 05m
Multiple Airlines
Mon 6/157:22 pm
TYS
-
ORD
1 stop28h 57m
Multiple Airlines
Deal found 4/28$212
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:55 am
ORD
-
TYS
2 stops28h 16m
Multiple Airlines
Tue 6/25:05 pm
TYS
-
ORD
1 stop20h 32m
Multiple Airlines
Deal found 4/28$219
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:52 pm
ORD
-
TYS
1 stop23h 37m
Multiple Airlines
Tue 6/25:05 pm
TYS
-
ORD
1 stop7h 10m
Multiple Airlines
Deal found 4/27$224
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:05 am
ORD
-
TYS
1 stop8h 54m
Multiple Airlines
Wed 6/31:02 pm
TYS
-
ORD
1 stop24h 35m
Multiple Airlines
Deal found 4/26$233
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 pm
ORD
-
TYS
1 stop15h 22m
Multiple Airlines
Tue 5/265:05 pm
TYS
-
ORD
1 stop20h 32m
Multiple Airlines
Deal found 4/29$237
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:52 am
ORD
-
TYS
1 stop7h 20m
Multiple Airlines
Tue 6/165:02 pm
TYS
-
ORD
1 stop20h 41m
Multiple Airlines
Deal found 4/28$238

Find flight deals from O'Hare Intl to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$205
(Kiwi.com)

One-way from

$82
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$318

Good round-trip deal

$293 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Chicago O'Hare Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago O'Hare Intl-Knoxville McGhee Tyson flights.
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From Chicago O'Hare Intl to Knoxville McGhee Tyson
Search Deals
One-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Chicago O'Hare Intl to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 6/27

5:50 pm-8:39 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Tue 6/30

5:55 pm-7:05 pm

Nonstop2h 10m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 6/9

9:30 pm-12:30 am

Nonstop2h 00m

Knoxville McGhee Tyson

Tue 6/16

8:20 am-9:28 am

Nonstop2h 08m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 7/29

2:12 pm-5:12 pm

Nonstop2h 00m

Knoxville McGhee Tyson

Sat 8/1

8:20 am-9:28 am

Nonstop2h 08m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 6/26

9:35 pm-12:35 am

Nonstop2h 00m

Knoxville McGhee Tyson

Mon 6/29

5:55 pm-7:05 pm

Nonstop2h 10m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 5/27

2:00 pm-9:25 pm

1 stop6h 25m

Knoxville McGhee Tyson

Sun 5/31

5:40 am-8:39 am

1 stop3h 59m

$269

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 6/4

2:00 pm-9:25 pm

1 stop6h 25m

Knoxville McGhee Tyson

Mon 6/8

7:15 am-1:04 pm

1 stop6h 49m

$269

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 6/26

5:30 am-11:09 am

1 stop4h 39m

Knoxville McGhee Tyson

Mon 6/29

5:40 am-10:13 am

1 stop5h 33m

$269

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 6/18

9:48 am-2:49 pm

1 stop4h 01m

Knoxville McGhee Tyson

Sat 6/20

5:37 pm-8:59 pm

1 stop4h 22m

$269
Quickest round-trip

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 6/5

6:07 pm-8:56 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Sun 6/7

6:30 am-7:29 am

Nonstop1h 59m

$279

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 5/13

7:00 am-2:20 pm

1 stop6h 20m

Knoxville McGhee Tyson

Wed 5/20

5:59 pm-11:59 pm

1 stop7h 00m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from O'Hare Intl to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from O'Hare Intl to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Knoxville

How far ahead should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

Booking 69 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $269). Flying from Chicago O'Hare Intl Airport to Knoxville in October is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to TYS?

Find hourly flight availability from O'Hare Intl to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.

It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville in the morning. Doing so could potentially save you 9% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Knoxville. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 30, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,464 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,464 reviews
Delta
7.9
Good
8,464 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,677 reviews
Delta
7.9
Good
8,464 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,681 reviews
Delta
7.9
Good
8,464 reviews

Entertainment

7.8

Boarding

8.1

Overall

7.9

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Chicago O'Hare Intl?

    Knoxville McGhee Tyson (TYS) is the airport you will fly into if you book a flight from Chicago O'Hare Intl to Knoxville. You should not have trouble finding flights to McGhee Tyson from Chicago O'Hare Intl; the airport handles an average of 13 inbound flights from Chicago O'Hare Intl per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Knoxville airport from Chicago O'Hare Intl. It is only a 11.3 mi journey from McGhee Tyson (TYS) to Knoxville’s city center.

  • How long is the flight from Chicago O'Hare Intl Airport to Knoxville?

    There are many flights that can get you from Chicago O'Hare Intl Airport to Knoxville in 1h 49m. Fly via United Airlines or Delta to get the fastest option. Chicago O'Hare Intl Airport and Knoxville are separated by a distance of 475 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Chicago O'Hare Intl Airport to Knoxville round-trip?

    Delta, at $148, was found to be the cheapest airline from Chicago O'Hare Intl Airport to Knoxville.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Chicago O'Hare Intl Airport to Knoxville for 52% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Knoxville?

    Consider SkyWest Airlines (82%), Aer Lingus (76%) or Air Canada (73%) when booking your flight. These represent the most reliable airlines when flying from Chicago O'Hare Intl Airport to Knoxville.

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Knoxville?

    Looking for the cheapest flight from Chicago O'Hare Intl Airport to Knoxville? While on average our users pay $450, our data indicates the cheapest price to be $168. The most popular route (Chicago O'Hare Intl - Knoxville McGhee Tyson), is priced around $229.

  • Can I find deals for flights from O'Hare Intl to Knoxville that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Knoxville.

  • Can I find deals for business class flights from O'Hare Intl to Knoxville?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $269). Flying from Chicago O'Hare Intl Airport to Knoxville in October is currently the most expensive (average of $371). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge

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Top 3 airlines flying from O'Hare Intl to Knoxville

Discover the top 3 airlines that operate flights from O'Hare Intl to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$148Average$208FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$189Average$308FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$189Average$316FlexibilityNo cancel feeOn-time71%

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