$111+ Cheap flights from O'Hare Intl (ORD) to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — TYS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from O'Hare Intl to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago O'Hare Intl to Knoxville McGhee Tyson are usually found in August or January, booked 90 days in advance, depart on a Saturday or Wednesday and return on a Friday
Cheap flight deals from O'Hare Intl to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from O'Hare Intl to KnoxvilleExplore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from O'Hare Intl to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:34 pm -
1 stop20h 08m
Mon 12/148:00 am -
2 stops14h 42m
Deal found 10/29![Multiple Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:30 am -
1 stop4h 57m
Fri 12/411:49 am -
1 stop5h 28m
Deal found 10/29![Delta logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:20 am -
2 stops25h 17m
Mon 12/71:58 pm -
1 stop7h 31m
Deal found 10/27![Multiple Airlines logo]()
$262
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:00 pm -
Nonstop1h 50m
Wed 11/258:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:59 pm -
Nonstop1h 51m
Fri 1/812:02 pm -
Nonstop2h 10m
Deal found 10/28![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Mon 11/308:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop4h 21m
Fri 12/47:44 am -
Nonstop2h 26m
Deal found 10/28![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Fri 11/277:01 am -
1 stop5h 43m
Deal found 10/28![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:47 pm -
Nonstop1h 50m
Sun 12/68:46 pm -
Nonstop2h 12m
Deal found 10/28![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:46 am -
1 stop7h 36m
Thu 12/246:00 am -
Nonstop2h 26m
Deal found 10/28![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:19 am -
1 stop4h 14m
Sat 12/54:24 pm -
Nonstop2h 05m
Deal found 10/29![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:19 am -
1 stop4h 14m
Fri 11/277:01 am -
1 stop6h 59m
Deal found 10/29![American Airlines logo]()
$281
Best flights from O'Hare Intl to KnoxvilleDiscover carefully curated flight deals from O'Hare Intl to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from O'Hare Intl to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:55 pm -
1 stop4h 51m
Sun 2/2111:30 am -
1 stop6h 07m
Deal found 10/29![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:59 pm -
Nonstop1h 55m
Fri 11/205:40 pm -
Nonstop2h 03m
Deal found 10/26![United Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:34 pm -
1 stop5h 40m
Sun 12/136:17 pm -
1 stop6h 39m
Deal found 10/26![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/22:20 pm -
Nonstop1h 53m
Mon 1/46:00 am -
Nonstop2h 11m
Deal found 10/26![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:00 pm -
1 stop6h 12m
Sat 11/214:00 pm -
1 stop5h 49m
Deal found 10/25![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:25 am -
1 stop6h 14m
Mon 1/45:15 am -
1 stop4h 25m
Deal found 10/26![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:50 am -
1 stop4h 58m
Tue 11/246:45 am -
Nonstop2h 09m
Deal found 10/25![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/111:10 am -
1 stop3h 58m
Sun 4/45:30 am -
1 stop5h 32m
Deal found 10/29![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:00 pm -
1 stop5h 49m
Sun 1/36:00 am -
Nonstop2h 11m
Deal found 10/26![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:30 am -
Nonstop1h 50m
Wed 12/166:20 am -
2 stops11h 31m
Deal found 10/26![United Airlines logo]()
$424
This KAYAK deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:59 pm -
1 stop4h 57m
Thu 11/194:00 pm -
1 stop4h 05m
Deal found 10/29![Delta logo]()
$418
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:00 am -
1 stop5h 52m
Thu 11/195:40 pm -
Nonstop2h 03m
Deal found 10/26![United Airlines logo]()
$447
Last-minute flights from O'Hare Intl to KnoxvilleDiscover last-minute flight deals from O'Hare Intl to Knoxville. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Knoxville. Data last updated October 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:30 am -
1 stop4h 58m
Thu 11/197:10 am -
1 stop4h 29m
Deal found 10/26![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:07 pm -
Nonstop1h 52m
Sat 11/211:56 pm -
Nonstop2h 04m
Deal found 10/29![United Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:00 pm -
Nonstop1h 50m
Wed 11/258:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:49 am -
1 stop6h 06m
Tue 12/17:10 am -
1 stop4h 49m
Deal found 10/26![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:19 am -
1 stop4h 14m
Fri 11/277:01 am -
1 stop6h 59m
Deal found 10/29![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Mon 11/308:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:08 pm -
Nonstop1h 44m
Fri 11/277:01 am -
1 stop5h 43m
Deal found 10/28![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:05 am -
1 stop4h 21m
Fri 12/47:44 am -
Nonstop2h 26m
Deal found 10/28![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:20 pm -
Nonstop1h 42m
Mon 11/308:50 pm -
Nonstop2h 09m
Deal found 10/28![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/285:19 am -
1 stop4h 14m
Sat 12/54:24 pm -
Nonstop2h 05m
Deal found 10/29![American Airlines logo]()
$280
One-way flights from O'Hare Intl to KnoxvilleSearch for one-way flight options from O'Hare Intl to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from O'Hare Intl to Knoxville. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:09 am -
Nonstop1h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$111
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:44 pm -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Delta logo]()
$121
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/189:32 pm -
Nonstop1h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$123
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/271:20 pm -
Nonstop1h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$131
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:31 am -
Nonstop1h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/138:25 am -
1 stop23h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$138
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:19 am -
1 stop4h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/143:24 pm -
1 stop21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:00 pm -
2 stops24h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$153
Find flight deals from O'Hare Intl to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $259 (Kiwi.com) |
One-way from | $111 (American Airlines) |
Popular in | September |
Cheapest in | August |
Average price | $387 |
Good round-trip deal | $336 or less |
Good one-way deal | $238 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Wed 12/9
2:10 pm-5:00 pm
Nonstop1h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$111
Quickest round-trip
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Fri 11/27
1:20 pm-4:02 pm
Nonstop1h 42m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$131
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Thu 1/14
3:24 pm-1:44 pm
1 stop21h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$148
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Sun 11/22
5:59 pm-8:54 pm
Nonstop1h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Mon 1/18
7:00 am-12:11 pm
1 stop4h 11m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$180
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Sat 4/17
7:10 am-1:29 pm
1 stop5h 19m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$185
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Mon 12/21
5:05 pm-10:46 pm
2 stops28h 41m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$193
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Fri 11/13
7:55 am-10:05 am
1 stop25h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$200
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Sun 12/13
7:18 am-10:14 am
Nonstop1h 56m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$224
ChicagoKnoxville
ORD Chicago O'Hare Intl - TYS Knoxville McGhee Tyson
ORDTYS
Chicago O'Hare Intl
Thu 11/12
5:59 pm-8:54 pm
Nonstop1h 55m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$244
Showing 1-10 of 24 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from O'Hare Intl with our price prediction graph.
ORD-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Knoxville
How far ahead should I book a flight from Chicago O'Hare Intl Airport to Knoxville?
Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago O'Hare Intl Airport to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Knoxville (average of $274). Flying from Chicago O'Hare Intl Airport to Knoxville in September is currently the most expensive (average of $418). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to TYS?
Find hourly flight availability from O'Hare Intl to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
It’s typically best to fly out from Chicago O'Hare Intl Airport to Knoxville at noon. Doing so could potentially save you 9% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Knoxville. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Knoxville flight should consider departing on Sunday evenings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 30, 2026.
See what other customers who have flown with United Airlines and American Airlines from Chicago O'Hare Intl Airport to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Comfort
7.3
Boarding
7.7
Food
6.7
Entertainment
7.1
Crew
8.1
Overall
7.3
Reviews
1 / 20
2.0
MediocreDawn,Aug 2026
ORD - DEN
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Morristown
Newport
Bryson City
Crossville
Murphy
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Top 2 airlines flying from O'Hare Intl to Knoxville
Discover the top 2 airlines that operate flights from O'Hare Intl to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$189 | Average$354 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$209 | Average$339 | FlexibilityNo cancel fee | On-time71% |