
Keep the following information in mind while searching for South Carolina to Kentucky flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $107 (Kiwi.com) |
One-way from | $91 (Kiwi.com) |
Good round-trip deal | $230 or less |
Good one-way deal | $191 or less |
Fly from
Fly to
Route
Depart
Return
CharlestonLouisville
CHS Charleston - SDF Louisville Intl
CHSSDF
Charleston
Fri 11/13
6:10 am-8:02 am
Nonstop1h 52m
Louisville Intl
Mon 11/16
7:59 pm-9:34 pm
Nonstop1h 35m
CharlestonLouisville
CHS Charleston - SDF Louisville Intl
CHSSDF
Charleston
Mon 12/7
6:10 am-8:02 am
Nonstop1h 52m
Louisville Intl
Fri 12/11
7:59 pm-9:34 pm
Nonstop1h 35m
CharlestonLouisville
CHS Charleston - SDF Louisville Intl
CHSSDF
Charleston
Fri 12/11
6:10 am-8:02 am
Nonstop1h 52m
Louisville Intl
Mon 12/14
10:25 am-4:43 pm
1 stop6h 18m
GreenvilleLouisville
GSP Greenville - SDF Louisville Intl
GSPSDF
Greenville
Sat 12/19
7:41 pm-12:23 am
1 stop4h 42m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
CharlestonLouisville
CHS Charleston - SDF Louisville Intl
CHSSDF
Charleston
Mon 11/9
6:10 am-8:02 am
Nonstop1h 52m
Louisville Intl
Fri 11/13
10:25 am-4:43 pm
1 stop6h 18m
GreenvilleLexington
GSP Greenville - LEX Lexington Blue Grass
GSPLEX
Greenville
Sat 11/21
5:06 pm-5:03 pm
1 stop23h 57m
Lexington Blue Grass
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
CharlestonLouisville
CHS Charleston - SDF Louisville Intl
CHSSDF
Charleston
Wed 11/11
7:54 pm-8:29 pm
2 stops24h 35m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
GreenvilleLouisville
GSP Greenville - SDF Louisville Intl
GSPSDF
Greenville
Sun 12/20
8:05 am-9:25 pm
2 stops13h 20m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Myrtle BeachLouisville
MYR Myrtle Beach Intl - SDF Louisville Intl
MYRSDF
Myrtle Beach Intl
Tue 3/30
8:16 pm-9:54 am
1 stop13h 38m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Myrtle BeachLouisville
MYR Myrtle Beach Intl - SDF Louisville Intl
MYRSDF
Myrtle Beach Intl
Tue 3/30
10:30 am-8:20 pm
2 stops9h 50m
Louisville Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Everything you need to know about your flight from South Carolina to Kentucky
Overall
Entertainment
Comfort
Boarding
Crew
Food
Reviews
James,Oct 2026
RSW - RDU
Overall
Entertainment
Comfort
Boarding
Crew
Food
Reviews
James,Oct 2026
RSW - RDU
Overall
Entertainment
Comfort
Boarding
Crew
Food
Reviews
James,Oct 2026
RSW - RDU
Overall
Entertainment
Comfort
Boarding
Crew
Food
Reviews
James,Oct 2026
RSW - RDU
Overall
Entertainment
Comfort
Boarding
Crew
Food
Reviews
James,Oct 2026
RSW - RDU
Find useful and relevant information for your journey from South Carolina to Kentucky. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$78 | Average$104 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$93 | Average$188 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$206 | Average$406 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$427 | FlexibilityNo cancel fee | On-time71% |