
Keep the following information in mind while searching for Kentucky to South Carolina flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $108 (Kiwi.com) |
One-way from | $58 (Kiwi.com) |
Popular in | January |
Cheapest in | July |
Average price | $338 |
Good round-trip deal | $131 or less |
Fly from
Fly to
Route
Depart
Return
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 11/13
7:59 pm-9:34 pm
Nonstop1h 35m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Wed 11/25
7:15 pm-12:15 am
1 stop5h 00m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Thu 11/26
6:45 am-4:35 pm
2 stops9h 50m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LexingtonCharleston
LEX Lexington Blue Grass - CHS Charleston
LEXCHS
Lexington Blue Grass
Thu 11/12
6:24 pm-9:01 pm
1 stop26h 37m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LexingtonCharleston
LEX Lexington Blue Grass - CHS Charleston
LEXCHS
Lexington Blue Grass
Sun 12/6
5:25 pm-9:01 pm
1 stop27h 36m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Fri 12/4
10:25 am-8:38 am
2 stops22h 13m
Charleston
Mon 12/7
6:10 am-8:02 am
Nonstop1h 52m
LouisvilleCharleston
SDF Louisville Intl - CHS Charleston
SDFCHS
Louisville Intl
Thu 3/25
6:14 pm-12:21 am
1 stop6h 07m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LouisvilleMyrtle Beach
SDF Louisville Intl - MYR Myrtle Beach Intl
SDFMYR
Louisville Intl
Thu 11/26
5:45 am-1:00 pm
2 stops7h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LouisvilleGreenville
SDF Louisville Intl - GSP Greenville
SDFGSP
Louisville Intl
Mon 11/9
6:53 pm-3:29 pm
2 stops20h 36m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
LexingtonMyrtle Beach
LEX Lexington Blue Grass - MYR Myrtle Beach Intl
LEXMYR
Lexington Blue Grass
Sun 11/22
5:55 pm-10:03 pm
1 stop4h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Everything you need to know about your flight from Kentucky to South Carolina
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Entertainment
Boarding
Overall
Comfort
Crew
Reviews
James,Oct 2026
RSW - RDU
Find useful and relevant information for your journey from Kentucky to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$63 | Average$114 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$88 | Average$155 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$226 | Average$399 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$234 | Average$351 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$234 | Average$444 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$388 | FlexibilityNo cancel fee | On-time63% |