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$449+ Cheap flights from Lexington to Florence, SC (LEX - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — FLO
Sep 3 — Sep 101
Thu 9/3
Thu 9/10
1 adult, Economy
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Cheap flight deals from Lexington to Florence

Cheapest flights from Lexington to Florence
Explore the most affordable flight options available from Lexington to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 4, 2026.

This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:00 pm
LEX
-
FLO
1 stop5h 59m
American Airlines
Wed 8/196:22 am
FLO
-
LEX
1 stop3h 49m
American Airlines
Deal found 7/31$551
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:00 pm
LEX
-
FLO
1 stop5h 59m
American Airlines
Mon 9/73:22 pm
FLO
-
LEX
1 stop5h 29m
American Airlines
Deal found 8/3$558
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3111:15 am
LEX
-
FLO
1 stop3h 41m
American Airlines
Mon 9/76:22 am
FLO
-
LEX
1 stop3h 49m
American Airlines
Deal found 8/3$642

Find flight deals from Lexington to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$551
(American Airlines)

One-way from

$449
(American Airlines)
Provider with most accurate pricing for Lexington Blue Grass-Florence flight deals.
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Provider most trusted by Cheapflights users for Lexington Blue Grass-Florence flights.
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From Lexington Blue Grass to Florence
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One-way flight from Lexington Blue Grass to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 4, 2026.
Use the filters below to find and compare flights from Lexington to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LexingtonFlorence

LEX - FLO

LEXFLO

Lexington Blue Grass

Tue 9/1

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Mon 9/7

3:22 pm-8:51 pm

1 stop5h 29m

$558
Quickest round-trip

LexingtonFlorence

LEX - FLO

LEXFLO

Lexington Blue Grass

Mon 8/31

11:15 am-2:56 pm

1 stop3h 41m

Florence

Mon 9/7

6:22 am-10:11 am

1 stop3h 49m

$642

LexingtonFlorence

LEX - FLO

LEXFLO

Lexington Blue Grass

Sat 8/15

5:00 pm-10:59 pm

1 stop5h 59m

Florence

Wed 8/19

3:22 pm-11:46 pm

2 stops8h 24m

$663
Cheapest one-way
Quickest one-way

LexingtonFlorence

LEX - FLO

LEXFLO

Lexington Blue Grass

Sat 10/3

7:36 am-1:18 pm

1 stop5h 42m

$449

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/2

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Lexington-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Florence, South Carolina?

    A quick flight from Lexington to Florence, South Carolina can take about 5h 59m. American Airlines provides one of the quickest options available for as low as $558. Airlines will cover a distance of 381 mi.

  • Can I find deals for flights from Lexington to Florence that include hotel bookings?

    Yes. In addition to deals on Lexington to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Florence.

  • Can I find deals for business class flights from Lexington to Florence?

    Yes. Cheapflights offers flight deals from Lexington to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter

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