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South Carolina

$39+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — CHS
Mar 4 — Mar 111
Wed 3/4
Wed 3/11
1 adult, Economy
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Cheap flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:19 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Fri 9/119:45 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$77
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/82:56 pm
CAK
-
MYR
Nonstop1h 33m
Allegiant Air
Thu 3/125:04 pm
MYR
-
CAK
Nonstop1h 41m
Allegiant Air
Deal found 2/1$78
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/152:41 pm
CAK
-
MYR
Nonstop1h 33m
Allegiant Air
Thu 3/195:04 pm
MYR
-
CAK
Nonstop1h 41m
Allegiant Air
Deal found 2/1$79
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:10 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Fri 9/119:45 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$83
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:08 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Fri 9/119:45 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$87
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:03 pm
CAK
-
MYR
Nonstop1h 37m
Breeze Airways
Fri 3/610:40 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$92
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:10 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Mon 9/149:45 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$93
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:08 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Mon 9/149:45 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 1/31$97
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:10 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Tue 6/210:38 am
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 2/1$98
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:37 am
CAK
-
MYR
Nonstop1h 33m
Allegiant Air
Thu 6/44:22 pm
MYR
-
CAK
Nonstop1h 41m
Allegiant Air
Deal found 2/1$99
This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:10 pm
CAK
-
MYR
Nonstop1h 40m
Breeze Airways
Wed 5/208:44 pm
MYR
-
CAK
Nonstop1h 43m
Breeze Airways
Deal found 2/1$101
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:09 am
DTW
-
CHS
1 stop10h 56m
Spirit Airlines
Mon 3/95:00 pm
CHS
-
DTW
1 stop7h 09m
Spirit Airlines
Deal found 1/31$110

Find flight deals from Ohio to South Carolina

Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated February 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$78
(Kiwi.com)

One-way from

$39
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$308

Good round-trip deal

$117 or less

Good one-way deal

$59 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Myrtle Beach Intl flights.
Search Deals
From Ohio to South Carolina
Search Deals
One-way flight from Ohio to South Carolina
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Ohio to South Carolina.
Search Deals
Price to beat on a one-way flight from Ohio to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.

Fly from

Ohio

Fly to

South Carolina

Route

Depart

Return

Price

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Mon 3/16

1:03 pm-2:40 pm

Nonstop1h 37m

Myrtle Beach Intl

Fri 3/20

10:40 am-12:23 pm

Nonstop1h 43m

$113

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Tue 7/14

4:10 pm-5:50 pm

Nonstop1h 40m

Myrtle Beach Intl

Tue 7/21

10:38 am-12:21 pm

Nonstop1h 43m

$118

PittsburghMyrtle Beach

PIT - MYR

PITMYR

Pittsburgh

Sun 5/10

5:41 pm-7:06 pm

Nonstop1h 25m

Myrtle Beach Intl

Sat 5/16

4:55 pm-6:21 pm

Nonstop1h 26m

$132

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Sat 7/4

1:19 pm-2:59 pm

Nonstop1h 40m

Myrtle Beach Intl

Sat 7/11

8:44 pm-10:27 pm

Nonstop1h 43m

$158

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 2/21

2:15 pm-4:05 pm

Nonstop1h 50m

Charlotte Douglas

Tue 2/24

1:11 pm-3:03 pm

Nonstop1h 52m

$159

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 2/26

10:06 am-12:08 pm

Nonstop2h 02m

Charlotte Douglas

Tue 3/3

5:25 am-10:56 am

1 stop5h 31m

$159

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 2/26

7:45 pm-9:32 pm

Nonstop1h 47m

Charlotte Douglas

Sun 3/1

6:00 am-7:52 am

Nonstop1h 52m

$179

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Mon 2/23

7:05 am-9:07 am

Nonstop2h 02m

Charlotte Douglas

Sun 3/1

6:00 am-7:52 am

Nonstop1h 52m

$179

CincinnatiCharlotte

CVG - CLT

CVGCLT

Cincinnati Cinci./N. Kentucky

Wed 3/4

3:20 pm-7:58 am

1 stop16h 38m

Charlotte Douglas

Mon 3/9

9:28 pm-7:23 am

1 stop9h 55m

$182

AkronMyrtle Beach

CAK - MYR

CAKMYR

Akron/Canton

Sat 6/27

1:19 pm-2:59 pm

Nonstop1h 40m

Myrtle Beach Intl

Sat 7/4

8:44 pm-10:27 pm

Nonstop1h 43m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 60 results
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Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South Carolina

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $41). Flying from Ohio to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 2, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 32% on flights from Ohio to South Carolina by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Ohio to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 2, 2026.
Read reviews from past customers who have flown Breeze Airways, Delta, and American Airlines from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.2
Very good
263 reviews
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,128 reviews
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.2
Good
11,210 reviews
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Allegiant Air
7.2
Good
707 reviews
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Spirit Airlines
6.3
Okay
8,394 reviews
Breeze Airways
8.2
Very good
263 reviews

Comfort

8.2

Overall

8.2

Boarding

8.3

Crew

8.7

Food

6.7

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Ohio to South Carolina flight route?

    This flight path from Ohio to South Carolina was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Ohio to South Carolina?

    There are many flights that can get you from Ohio to South Carolina in 1h 25m. Fly via Breeze Airways, Spirit Airlines, or Delta to get the fastest option. Ohio and South Carolina are separated by a distance of 476 mi. All flights are typically nonstop.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $36. However, be on the lookout for offers from Allegiant Air and Breeze Airways, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $41). Flying from Ohio to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 8 airlines flying from Ohio to South Carolina

Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$46Average$183FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$54Average$127FlexibilityNo cancel feeOn-time88%
FrontierCheapest$57Average$136FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$67Average$166FlexibilityNo cancel feeOn-time65%
DeltaCheapest$100Average$317FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$130Average$337FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$164Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$350FlexibilityNo cancel feeOn-time63%

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