HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$44+ Cheap flights from Ohio to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — CHS
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Ohio to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Ohio to South Carolina

Cheapest flights from Ohio to South Carolina
Explore the most affordable flight options available from Ohio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:40 pmCAK - CHS
Nonstop1h 49mBreeze Airways
Thu 12/257:00 amCHS - CAK
Nonstop1h 52mBreeze Airways
Deal found 12/15$152
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:15 pmDTW - CLT
Nonstop1h 53mFrontier
Sun 12/289:24 amCLT - DTW
Nonstop1h 56mFrontier
Deal found 12/16$158
This CheapOair deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:48 pmCLE - CLT
1 stop27h 21mFrontier
Tue 12/309:24 pmCLT - CLE
1 stop10h 19mFrontier
Deal found 12/15$163
This Breeze Airways deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:25 pmCAK - CHS
Nonstop1h 49mBreeze Airways
Thu 1/17:00 amCHS - CAK
Nonstop1h 52mBreeze Airways
Deal found 12/15$163
This Frontier deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:40 amCLE - CLT
1 stop11h 21mFrontier
Mon 1/56:18 pmCLT - CLE
Nonstop1h 45mFrontier
Deal found 12/14$167
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 amCLE - CLT
1 stop29h 07mFrontier
Wed 12/314:11 pmCLT - CLE
1 stop6h 25mFrontier
Deal found 12/15$170
This Breeze Airways deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:40 pmCAK - CHS
Nonstop1h 49mBreeze Airways
Sun 12/287:00 amCHS - CAK
Nonstop1h 52mBreeze Airways
Deal found 12/16$173
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 amCLE - CLT
1 stop29h 07mFrontier
Tue 12/309:24 pmCLT - CLE
1 stop10h 19mFrontier
Deal found 12/15$175
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:40 pmCAK - CHS
Nonstop1h 49mBreeze Airways
Tue 12/307:00 amCHS - CAK
Nonstop1h 52mBreeze Airways
Deal found 12/15$178
This Frontier deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:40 amCLE - CLT
1 stop11h 21mFrontier
Wed 12/244:11 pmCLT - CLE
1 stop6h 25mFrontier
Deal found 12/15$183
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:15 pmCAK - CHS
Nonstop1h 49mBreeze Airways
Thu 12/257:00 amCHS - CAK
Nonstop1h 52mBreeze Airways
Deal found 12/15$183
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:28 pmDTW - SAV
1 stop15h 00mSpirit Airlines
Tue 1/61:23 pmSAV - DTW
1 stop10h 28mSpirit Airlines
Deal found 12/16$184

Find flight deals from Ohio to South Carolina

Keep the following information in mind while searching for Ohio to South Carolina flight deals. Data was last updated December 16, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$87
(Kiwi.com)

One-way from

$44
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$291

Good round-trip deal

$91 or less

Good one-way deal

$59 or less
Provider with most accurate pricing for Cleveland Hopkins Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Myrtle Beach Intl flights.
Search Deals
From Ohio to South Carolina
Search Deals
One-way flight from Ohio to South Carolina
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Ohio to South Carolina.
Search Deals
Price to beat on a one-way flight from Ohio to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Ohio to South Carolina that are best for you.

Fly from

Ohio

Fly to

South Carolina

Route

Depart

Return

Price

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Tue 1/13

8:17 pm-10:06 pm

Nonstop1h 49m

Charleston

Tue 1/20

7:00 am-8:52 am

Nonstop1h 52m

$87

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 2/5

8:17 pm-10:06 pm

Nonstop1h 49m

Charleston

Sun 2/8

7:00 am-8:52 am

Nonstop1h 52m

$88

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 2/5

8:17 pm-10:06 pm

Nonstop1h 49m

Charleston

Mon 2/9

10:53 am-12:45 pm

Nonstop1h 52m

$88

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Tue 1/6

8:25 pm-10:14 pm

Nonstop1h 49m

Charleston

Thu 1/8

7:00 am-8:52 am

Nonstop1h 52m

$108

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Mon 3/9

4:20 pm-6:09 pm

Nonstop1h 49m

Charleston

Tue 3/10

7:00 am-8:52 am

Nonstop1h 52m

$108

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Sun 3/1

8:17 pm-10:06 pm

Nonstop1h 49m

Charleston

Wed 3/4

12:15 pm-2:07 pm

Nonstop1h 52m

$108

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Fri 2/13

4:20 pm-6:09 pm

Nonstop1h 49m

Charleston

Fri 2/27

10:53 am-12:45 pm

Nonstop1h 52m

$113

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Thu 1/15

8:17 pm-10:06 pm

Nonstop1h 49m

Charleston

Sun 1/18

7:00 am-8:52 am

Nonstop1h 52m

$123

AkronCharleston

CAK - CHS

CAKCHS

Akron/Canton

Sat 3/7

2:47 pm-4:36 pm

Nonstop1h 49m

Charleston

Thu 3/12

7:00 am-8:52 am

Nonstop1h 52m

$128

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 1/29

7:45 pm-9:32 pm

Nonstop1h 47m

Charlotte Douglas

Sat 1/31

6:00 am-7:52 am

Nonstop1h 52m

$139

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Ohio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to South Carolina

What is the cheapest month to book a flight from Ohio to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $41). Flying from Ohio to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to SC?

Find hourly flight availability from Ohio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 19% on flights from Ohio to South Carolina by exploring options for tickets in the afternoon.

What is the cheapest day to fly from Ohio to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Ohio to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Ohio to South Carolina flight should consider departing on Saturday afternoons when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 16, 2025.
Read reviews from past customers who have flown Breeze Airways, Delta, and American Airlines from Ohio to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
248 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Delta
7.9
Good
8,009 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,047 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Allegiant Air
7.2
Good
700 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Spirit Airlines
6.3
Okay
8,188 reviews
Breeze Airways
8.2
Very good
248 reviews

Food

6.7

Entertainment

6.7

Boarding

8.4

Comfort

8.2

Overall

8.2

Crew

8.8

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from Ohio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Ohio to South Carolina flight route?

    This flight path from Ohio to South Carolina was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Ohio to South Carolina?

    There are many flights that can get you from Ohio to South Carolina in 1h 47m. Fly via Breeze Airways, Delta, or Frontier to get the fastest option. Ohio and South Carolina are separated by a distance of 500 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Ohio to South Carolina one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $36. However, be on the lookout for offers from Allegiant Air and Breeze Airways, as they are both options that can get you from Ohio to South Carolina for a low price.

  • Can I find deals for flights from Ohio to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ohio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to South Carolina.

  • Can I find deals for business class flights from Ohio to South Carolina?

    Yes. Cheapflights offers flight deals from Ohio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Ohio to South Carolina (average of $41). Flying from Ohio to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Ohio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Miami flights
Newark to Fort Lauderdale flights
Newark to Miami flights
LaGuardia to Fort Lauderdale flights
LaGuardia to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
John F Kennedy Intl to Orlando flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to Los Angeles flights
Los Angeles to John F Kennedy Intl flights
Newark to West Palm Beach flights
Newark to Orlando flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to Dallas/Fort Worth flights
LaGuardia to Orlando flights
Los Angeles to Newark flights
Newark to Las Vegas flights
Newark to Los Angeles flights
John F Kennedy Intl to West Palm Beach flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Las Vegas flights
O'Hare Intl to Dallas/Fort Worth flights
Minneapolis to Sky Harbor Intl flights
Dallas/Fort Worth to Las Vegas flights
Baltimore to Fort Lauderdale flights
LaGuardia to Dallas/Fort Worth flights
San Francisco to Las Vegas flights
John F Kennedy Intl to Tampa flights
Seattle to Los Angeles flights
Dallas/Fort Worth to Seattle flights
Seattle to Dallas/Fort Worth flights
Newark to Dallas/Fort Worth flights
Los Angeles to Seattle flights
Atlanta to John F Kennedy Intl flights
Seattle to Las Vegas flights
Los Angeles to Honolulu flights
Reagan-National to Miami flights
Dulles Intl to Miami flights
Newark to Tampa flights
San Francisco to John F Kennedy Intl flights
John F Kennedy Intl to Atlanta flights
O'Hare Intl to Fort Lauderdale flights
Dallas/Fort Worth to Orlando flights
John F Kennedy Intl to San Francisco flights
Atlanta to LaGuardia flights
Boston to Fort Lauderdale flights
Dallas/Fort Worth to Denver flights
Boston to Miami flights

Top 8 airlines flying from Ohio to South Carolina

Discover the top 8 airlines that operate flights from Ohio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$54Average$123FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$59Average$189FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$72Average$140FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$76Average$162FlexibilityNo cancel feeOn-time65%
DeltaCheapest$108Average$320FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$153Average$339FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$164Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$196Average$353FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.