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South America

$88+ Cheap flights from South Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from South Carolina to South America

Cheapest flights from South Carolina to South America
Explore the most affordable flight options available from South Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This CheapOair deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
CLT
-
MDE
1 stop8h 13m
Spirit Airlines
Wed 5/272:10 pm
MDE
-
CLT
1 stop9h 30m
Spirit Airlines
Deal found 2/1$214
This Travelocity deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Wed 3/112:15 pm
MDE
-
CLT
1 stop8h 41m
Spirit Airlines
Deal found 2/1$223
This Cheapflightsfares deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/191:20 pm
CLT
-
MDE
1 stop12h 01m
Spirit Airlines
Tue 3/242:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 2/4$227
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:00 am
CLT
-
MDE
1 stop8h 22m
Spirit Airlines
Tue 3/242:17 pm
MDE
-
CLT
1 stop9h 21m
Spirit Airlines
Deal found 2/2$228
This Travelocity deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:13 pm
CLT
-
BOG
2 stops17h 34m
Spirit Airlines
Mon 2/233:06 pm
BOG
-
CLT
1 stop17h 20m
Spirit Airlines
Deal found 2/2$236
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
CLT
-
BOG
1 stop8h 11m
Spirit Airlines
Mon 3/302:10 pm
BOG
-
CLT
1 stop9h 28m
Spirit Airlines
Deal found 2/1$237
This Cheapflightsfares deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:55 am
CLT
-
BOG
1 stop8h 15m
Spirit Airlines
Mon 2/233:06 pm
BOG
-
CLT
1 stop17h 20m
Spirit Airlines
Deal found 2/3$238
This Cheapflightsfares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:20 pm
CLT
-
MDE
1 stop12h 01m
Spirit Airlines
Thu 4/302:10 pm
MDE
-
CLT
1 stop17h 16m
Spirit Airlines
Deal found 2/2$239
This Expedia deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:20 pm
CLT
-
MDE
1 stop12h 01m
Spirit Airlines
Tue 3/172:17 pm
MDE
-
CLT
1 stop17h 04m
Spirit Airlines
Deal found 2/3$240
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:55 am
CLT
-
BOG
1 stop8h 15m
Spirit Airlines
Mon 2/233:06 pm
BOG
-
CLT
1 stop17h 20m
Spirit Airlines
Deal found 2/2$243
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:55 am
CLT
-
CTG
1 stop7h 15m
Spirit Airlines
Wed 3/42:21 pm
CTG
-
CLT
1 stop9h 35m
Spirit Airlines
Deal found 2/2$243
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:55 am
CLT
-
MDE
1 stop8h 18m
Spirit Airlines
Thu 3/53:15 pm
MDE
-
CLT
1 stop17h 11m
Spirit Airlines
Deal found 2/2$244

Find flight deals from South Carolina to South America

Keep the following information in mind while searching for South Carolina to South America flight deals. Data was last updated February 5, 2026.

Round-trip from

$214
(CheapOair)

One-way from

$88
(Travelocity)
From South Carolina to South America
Search Deals
One-way flight from South Carolina to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from South Carolina to South America that are best for you.

Fly from

South Carolina

Fly to

South America

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 4/29

6:00 am-1:13 pm

1 stop8h 13m

Medellín Jose Maria Cordova Intl

Wed 5/27

2:10 pm-12:40 am

1 stop9h 30m

$214

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 3/7

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Wed 3/11

2:15 pm-11:56 pm

1 stop8h 41m

$223

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 4/1

6:00 am-1:22 pm

1 stop8h 22m

Medellín Jose Maria Cordova Intl

Wed 4/29

2:10 pm-12:40 am

1 stop9h 30m

$227

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Thu 3/19

1:20 pm-12:21 am

1 stop12h 01m

Medellín Jose Maria Cordova Intl

Tue 3/24

2:17 pm-12:38 am

1 stop9h 21m

$227

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Wed 2/18

7:13 pm-12:47 pm

2 stops17h 34m

Bogotá El Dorado

Mon 2/23

3:06 pm-8:26 am

1 stop17h 20m

$236

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Fri 2/20

5:55 am-2:10 pm

1 stop8h 15m

Bogotá El Dorado

Mon 2/23

3:06 pm-8:26 am

1 stop17h 20m

$238

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Sat 3/14

9:00 pm-1:11 pm

1 stop17h 11m

Bogotá El Dorado

Mon 3/23

2:10 pm-8:21 am

1 stop17h 11m

$243

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/2

5:55 am-2:13 pm

1 stop8h 18m

Medellín Jose Maria Cordova Intl

Thu 3/5

3:15 pm-11:56 pm

1 stop8h 41m

$245

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Tue 2/17

5:55 am-2:10 pm

1 stop8h 15m

Bogotá El Dorado

Mon 2/23

3:06 pm-4:54 pm

2 stops25h 48m

$246

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 3/23

9:00 pm-1:22 pm

1 stop17h 22m

Medellín Jose Maria Cordova Intl

Tue 3/31

10:49 am-7:48 pm

1 stop7h 59m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to South America

What is the cheapest month to book a flight from South Carolina to South America?

Currently, September is the cheapest month in which you can book a flight from South Carolina to South America (average of $176). Flying from South Carolina to South America in October is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SA?

Find hourly flight availability from South Carolina to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 5, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 31% on flights from South Carolina to South America by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to South America?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to South America. Price data was last updated on March 23, 2025.

Travelers seeking maximum savings on their South Carolina to South America flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to South America?

    A quick flight from South Carolina to South America can take about 8h 13m. Spirit Airlines provides one of the quickest options available for as low as $214. South Carolina and South America are separated by a distance of 2037 mi.

  • What are the cheapest airlines to fly from South Carolina to South America one-way?

    $103 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $296 and $313, respectively.

  • Can I find deals for flights from South Carolina to South America that include hotel bookings?

    Yes. In addition to deals on South Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to South America.

  • Can I find deals for business class flights from South Carolina to South America?

    Yes. Cheapflights offers flight deals from South Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to South America?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to South America (average of $176). Flying from South Carolina to South America in October is currently the most expensive (average of $486). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to South America

Discover the top 4 airlines that operate flights from South Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$301Average$883FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$327Average$395FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$458Average$827FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$494Average$778FlexibilityNo cancel feeOn-time81%

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