HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$126+ Cheap flights from South Carolina to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to South America

Keep the following information in mind while searching for South Carolina to South America flight deals. Data was last updated June 12, 2025.

Round-trip from

$309
(Cheapflightsfares)

One-way from

$134
(Booking.com)
From South Carolina to South America
Search Deals
One-way flight from South Carolina to South America
Search Deals

Find flight deals from South Carolina to South America

Cheapest flights from South Carolina to South America
Explore the most affordable flight options available from South Carolina to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/196:00 amCLT - BOG
1 stop8h 05mSpirit Airlines
Tue 7/222:00 pmBOG - CLT
1 stop17h 26mSpirit Airlines
Deal found 6/10$309
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/188:21 pmCLT - CTG
1 stop16h 54mSpirit Airlines
Tue 7/221:28 pmCTG - CLT
1 stop7h 48mSpirit Airlines
Deal found 6/11$316
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/286:20 amCLT - MDE
1 stop7h 44mSpirit Airlines
Thu 7/312:10 pmMDE - CLT
1 stop17h 16mSpirit Airlines
Deal found 6/10$366
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:26 pmGSP - MDE
1 stop18h 25mMultiple Airlines
Wed 9/101:46 pmMDE - GSP
1 stop19h 42mMultiple Airlines
Deal found 6/10$371
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/309:02 pmCLT - CLO
1 stop17h 18mSpirit Airlines
Wed 7/92:15 pmCLO - CLT
2 stops16h 38mSpirit Airlines
Deal found 6/12$396
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/188:21 pmCLT - BOG
3 stops26h 56mMultiple Airlines
Tue 7/225:00 amBOG - CLT
2 stops16h 16mMultiple Airlines
Deal found 6/10$403
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/236:00 amCLT - MDE
2 stops13h 24mMultiple Airlines
Wed 7/306:57 pmMDE - CLT
2 stops26h 19mMultiple Airlines
Deal found 6/11$413
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:00 amCLT - MDE
1 stop15h 10mUnited Airlines
Tue 10/149:45 amMDE - CLT
1 stop11h 14mUnited Airlines
Deal found 6/10$432
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/132:46 pmCLT - MDE
1 stop9h 48mAmerican Airlines
Thu 8/2812:40 amMDE - CLT
1 stop12h 16mAmerican Airlines
Deal found 6/12$435
This Avianca Connect deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/811:28 amCLT - GYE
2 stops15h 37mMultiple Airlines
Mon 7/143:15 amGYE - CLT
2 stops18h 01mMultiple Airlines
Deal found 6/10$448
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/289:02 pmCLT - CTG
1 stop16h 08mMultiple Airlines
Tue 7/17:11 amCTG - CLT
3 stops33h 47mMultiple Airlines
Deal found 6/11$453
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:25 amCLT - BOG
1 stop11h 50mDelta
Fri 9/191:35 amBOG - CLT
2 stops16h 08mDelta
Deal found 6/12$477

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from South Carolina to South America that are best for you.

Fly from

South Carolina

Fly to

South America

Route

Depart

Return

Price

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Sat 7/19

6:00 am-1:05 pm

1 stop8h 05m

Bogotá El Dorado

Tue 7/22

2:00 pm-8:26 am

1 stop17h 26m

$309

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Fri 7/18

8:21 pm-12:15 pm

1 stop16h 54m

Cartagena Rafael Nunez

Tue 7/22

1:28 pm-10:16 pm

1 stop7h 48m

$316

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Mon 7/28

6:20 am-1:04 pm

1 stop7h 44m

Medellín Jose Maria Cordova Intl

Thu 7/31

2:10 pm-8:26 am

1 stop17h 16m

$366

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 9/5

7:26 pm-12:51 pm

1 stop18h 25m

Medellín Jose Maria Cordova Intl

Wed 9/10

1:46 pm-10:28 am

1 stop19h 42m

$371

CharlotteCali

CLT - CLO

CLTCLO

Charlotte Douglas

Mon 6/30

9:02 pm-1:20 pm

1 stop17h 18m

Cali Alfonso B. Aragon Intl

Wed 7/9

2:15 pm-7:53 am

2 stops16h 38m

$396

CharlotteBogotá

CLT - BOG

CLTBOG

Charlotte Douglas

Fri 7/18

8:21 pm-10:17 pm

3 stops26h 56m

Bogotá El Dorado

Tue 7/22

5:00 am-10:16 pm

2 stops16h 16m

$403

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 7/23

6:00 am-6:24 pm

2 stops13h 24m

Medellín Jose Maria Cordova Intl

Wed 7/30

6:57 pm-10:16 pm

2 stops26h 19m

$413

CharlotteCartagena

CLT - CTG

CLTCTG

Charlotte Douglas

Sat 6/28

9:02 pm-12:10 pm

1 stop16h 08m

Cartagena Rafael Nunez

Sat 7/12

4:50 am-8:26 am

3 stops26h 36m

$434

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 8/13

2:46 pm-11:34 pm

1 stop9h 48m

Medellín Jose Maria Cordova Intl

Thu 8/28

12:40 am-1:56 pm

1 stop12h 16m

$435

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 9/3

7:46 pm-9:10 pm

2 stops26h 24m

Medellín Jose Maria Cordova Intl

Tue 9/9

9:45 am-10:26 am

2 stops23h 41m

$436

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to South America

Have a flexible travel schedule? Discover the best time to fly to South America from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to South America

What is the cheapest month to book a flight from South Carolina to South America?

Currently, May is the cheapest month in which you can book a flight from South Carolina to South America (average of $359). Flying from South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SA?

Find hourly flight availability from South Carolina to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to South America as you normally would.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
GOL
7.3
Good
1,073 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to South America one-way?

    $134 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Avianca and Copa Airlines, with prices starting from $294 and $304, respectively.

  • Can I find deals for flights from South Carolina to South America that include hotel bookings?

    Yes. In addition to deals on South Carolina to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to South America.

  • Can I find deals for business class flights from South Carolina to South America?

    Yes. Cheapflights offers flight deals from South Carolina to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to South America?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to South America (average of $359). Flying from South Carolina to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to South America

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Miami flights
Dallas/Fort Worth to LaGuardia flights
John F Kennedy Intl to Cancún flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to Seattle flights
John F Kennedy Intl to O'Hare Intl flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Luis Munoz Marin Intl flights
Los Angeles to Seattle flights
Los Angeles to Newark flights
Newark to Cancún flights
Los Angeles to Haneda flights
Dallas/Fort Worth to Newark flights
John F Kennedy Intl to Orlando flights
Newark to Miami flights
Newark to Los Angeles flights
LaGuardia to O'Hare Intl flights
LaGuardia to Miami flights
Newark to Seattle flights
Dallas/Fort Worth to Cancún flights
John F Kennedy Intl to Seattle flights
O'Hare Intl to John F Kennedy Intl flights
John F Kennedy Intl to Heathrow flights
John F Kennedy Intl to Charles de Gaulle flights
Dallas/Fort Worth to O'Hare Intl flights
LaGuardia to Dallas/Fort Worth flights
John F Kennedy Intl to Fort Lauderdale flights
San Francisco to John F Kennedy Intl flights
Seattle to Los Angeles flights
LaGuardia to Fort Lauderdale flights
Newark to Orlando flights
San Francisco to Newark flights
John F Kennedy Intl to Las Vegas flights
John F Kennedy Intl to San Francisco flights
Los Angeles to Honolulu flights
George Bush Intcntl to Cancún flights
John F Kennedy Intl to Santiago de los Caballeros flights
Los Angeles to O'Hare Intl flights
Dallas/Fort Worth to Las Vegas flights
O'Hare Intl to Cancún flights
Newark to O'Hare Intl flights
Los Angeles to Narita flights
John F Kennedy Intl to Mexico City flights
Newark to Charles de Gaulle flights
John F Kennedy Intl to Leonardo da Vinci/Fiumicino flights
O'Hare Intl to Seattle flights
Dallas/Fort Worth to Los Angeles flights
O'Hare Intl to Las Vegas flights

Top 4 airlines flying from South Carolina to South America

Discover the top 4 airlines that operate flights from South Carolina to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$333Average$443FlexibilityNo cancel feeOn-time65%
DeltaCheapest$405Average$863FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$405Average$817FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$502Average$869FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.