$370+ Cheap flights from Charlotte (CLT) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to Santiago
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Best
Last-minute
One-way
Cheapest flights from Charlotte to SantiagoExplore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
2 stops31h 36m
Tue 10/610:20 am -
1 stop28h 35m
Deal found 9/6![Multiple Airlines logo]()
$863
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:27 pm -
2 stops32h 28m
Sat 10/1711:55 pm -
1 stop22h 00m
Deal found 9/6![Multiple Airlines logo]()
$911
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:27 am -
2 stops34h 09m
Sat 12/511:10 pm -
1 stop14h 29m
Deal found 9/5![Multiple Airlines logo]()
$912
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:32 am -
2 stops34h 00m
Mon 9/219:30 am -
2 stops36h 44m
Deal found 9/6![Multiple Airlines logo]()
$917
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:41 pm -
1 stop29h 54m
Sun 11/158:35 pm -
2 stops26h 11m
Deal found 9/4![Multiple Airlines logo]()
$943
This Expedia deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/284:59 pm -
1 stop11h 41m
Wed 1/1311:00 pm -
1 stop12h 40m
Deal found 9/5![LATAM Airlines logo]()
$1,082
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:00 pm -
1 stop14h 55m
Fri 10/305:00 am -
2 stops16h 46m
Deal found 9/4![Multiple Airlines logo]()
$1,086
This Expedia deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:16 pm -
2 stops20h 24m
Thu 1/2111:00 pm -
1 stop14h 04m
Deal found 9/5![LATAM Airlines logo]()
$1,087
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:01 pm -
1 stop33h 34m
Sun 12/68:35 pm -
2 stops17h 04m
Deal found 9/6![Multiple Airlines logo]()
$1,098
Best flights from Charlotte to SantiagoDiscover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2410:00 am -
2 stops17h 20m
Mon 4/267:45 am -
2 stops16h 08m
Deal found 9/4![LATAM Airlines logo]()
$915
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:00 pm -
1 stop14h 55m
Fri 10/305:00 am -
2 stops16h 46m
Deal found 9/8![Multiple Airlines logo]()
$1,102
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:15 pm -
2 stops17h 45m
Sun 11/298:13 am -
2 stops17h 44m
Deal found 9/6![Delta logo]()
$1,229
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:03 pm -
1 stop18h 07m
Fri 10/3010:15 pm -
1 stop13h 33m
Deal found 9/4![American Airlines logo]()
$1,229
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:45 am -
2 stops15h 35m
Wed 4/147:45 pm -
2 stops18h 09m
Deal found 9/7![LATAM Airlines logo]()
$1,004
This Mytrip deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:10 pm -
3 stops33h 53m
Sun 12/68:35 pm -
3 stops45h 51m
Deal found 9/6![Multiple Airlines logo]()
$1,118
This Mytrip deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:10 pm -
2 stops32h 25m
Sun 11/1511:50 pm -
2 stops23h 16m
Deal found 9/4![Multiple Airlines logo]()
$1,205
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:15 pm -
2 stops21h 45m
Mon 11/27:05 pm -
2 stops17h 05m
Deal found 9/8![LATAM Airlines logo]()
$1,293
Last-minute flights from Charlotte to SantiagoDiscover last-minute flight deals from Charlotte to Santiago. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Santiago. Data last updated September 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/139:32 am -
2 stops34h 00m
Mon 9/219:30 am -
2 stops36h 44m
Deal found 9/6![Multiple Airlines logo]()
$917
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
2 stops31h 36m
Tue 10/610:20 am -
1 stop28h 35m
Deal found 9/6![Multiple Airlines logo]()
$863
This Mytrip deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:40 pm -
3 stops32h 31m
Mon 11/308:35 pm -
3 stops26h 31m
Deal found 9/5![Multiple Airlines logo]()
$1,255
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:27 am -
2 stops34h 09m
Sat 12/511:10 pm -
1 stop14h 29m
Deal found 9/5![Multiple Airlines logo]()
$912
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:27 pm -
2 stops32h 28m
Sat 10/1711:55 pm -
1 stop22h 00m
Deal found 9/6![Multiple Airlines logo]()
$911
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:00 pm -
1 stop14h 55m
Fri 10/305:00 am -
2 stops16h 46m
Deal found 9/4![Multiple Airlines logo]()
$1,086
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:03 pm -
1 stop18h 07m
Fri 10/3010:15 pm -
1 stop13h 33m
Deal found 9/4![American Airlines logo]()
$1,229
One-way flights from Charlotte to SantiagoSearch for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:34 pm -
3 stops33h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:30 pm -
1 stop12h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$672
This FlightHub deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:00 pm -
3 stops25h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![LATAM Airlines logo]()
$1,168
This deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/224:42 pm -
1 stop14h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$1,374
Find flight deals from Charlotte to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $863 (Kiwi.com) |
One-way from | $370 (Kiwi.com) |
Popular in | August |
Cheapest in | November |
Average price | $1,244 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 9/30
1:34 pm-11:39 pm
3 stops33h 05m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$370
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 9/30
2:35 pm-8:00 am
2 stops16h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$672
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 2/24
10:00 am-5:20 am
2 stops17h 20m
Santiago Arturo Merino Benitez
Mon 4/26
7:45 am-11:53 pm
2 stops16h 08m
$915
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 1/20
11:45 am-5:20 am
2 stops15h 35m
Santiago Arturo Merino Benitez
Wed 4/14
7:45 pm-1:54 pm
2 stops18h 09m
$1,004
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 10/7
3:00 pm-6:55 am
1 stop14h 55m
Santiago Arturo Merino Benitez
Fri 10/30
5:00 am-8:46 pm
2 stops16h 46m
$1,102
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Sun 11/22
5:10 pm-5:03 am
3 stops33h 53m
Santiago Arturo Merino Benitez
Sun 12/6
8:35 pm-4:26 pm
3 stops45h 51m
$1,118
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Mon 11/9
5:10 pm-3:35 am
2 stops32h 25m
Santiago Arturo Merino Benitez
Sun 11/15
11:50 pm-9:06 pm
2 stops23h 16m
$1,205
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Thu 11/19
7:15 pm-3:00 pm
2 stops17h 45m
Santiago Arturo Merino Benitez
Sun 11/29
8:13 am-11:57 pm
2 stops17h 44m
$1,229
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Wed 10/7
1:03 pm-8:10 am
1 stop18h 07m
Santiago Arturo Merino Benitez
Fri 10/30
10:15 pm-10:48 am
1 stop13h 33m
$1,229
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Thu 10/29
7:15 pm-6:00 pm
2 stops21h 45m
Santiago Arturo Merino Benitez
Mon 11/2
7:05 pm-10:10 am
2 stops17h 05m
$1,293
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Charlotte to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charlotte-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Charlotte-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Charlotte-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charlotte-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charlotte to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
CLT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 9, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andAmerican Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Crew
8.5
Food
7.2
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charlotte to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Santiago by cabin class
Find flights from Charlotte to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Santiago flights
Browse other Charlotte and Santiago flight options. Last updated on September 9, 2026.
Other flights from Charlotte
Browse through other flights departing from Charlotte. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 3 airlines flying from Charlotte to Santiago
Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$714 | Average$924 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$754 | Average$1,079 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$760 | Average$1,124 | FlexibilityNo cancel fee | On-time81% |