$309+ Cheap flights from Charlotte (CLT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Sep 8 — Sep 151
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to Santiago
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Cheapest flights from Charlotte to SantiagoExplore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm -
2 stops38h 00m
Fri 8/2812:30 am -
2 stops31h 31m
Deal found 8/5![Multiple Airlines logo]()
$679
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:32 am -
2 stops19h 13m
Sat 9/261:30 am -
2 stops17h 51m
Deal found 8/5![Multiple Airlines logo]()
$707
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:32 am -
2 stops17h 24m
Tue 9/2911:55 pm -
1 stop15h 00m
Deal found 8/5![Multiple Airlines logo]()
$815
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
1 stop31h 56m
Tue 10/1312:23 pm -
2 stops50h 24m
Deal found 8/6![Multiple Airlines logo]()
$824
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:59 pm -
2 stops23h 37m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$856
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
2 stops31h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$857
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:59 pm -
2 stops31h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$859
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:00 pm -
2 stops30h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$860
Best flights from Charlotte to SantiagoDiscover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:32 am -
2 stops19h 13m
Sat 9/261:30 am -
2 stops17h 51m
Deal found 8/5![Multiple Airlines logo]()
$707
This Copa Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am -
2 stops18h 48m
Fri 11/131:02 am -
2 stops19h 46m
Deal found 8/4![Copa Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:20 pm -
1 stop15h 20m
Tue 12/111:10 pm -
1 stop16h 22m
Deal found 8/6![Delta logo]()
$994
This LATAM Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:59 pm -
2 stops21h 01m
Sat 1/238:13 am -
2 stops17h 40m
Deal found 8/6![LATAM Airlines logo]()
$994
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:56 am -
2 stops43h 49m
Sat 8/296:40 am -
3 stops30h 33m
Deal found 8/5![Multiple Airlines logo]()
$756
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops21h 46m
Tue 11/171:02 am -
2 stops35h 20m
Deal found 8/6![Copa Airlines logo]()
$908
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:59 pm -
1 stop15h 56m
Mon 11/95:07 am -
2 stops16h 48m
Deal found 8/8![Multiple Airlines logo]()
$867
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:00 pm -
2 stops16h 40m
Tue 10/138:50 am -
2 stops16h 09m
Deal found 8/6![Delta logo]()
$1,084
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:21 pm -
1 stop35h 04m
Thu 12/311:55 pm -
1 stop15h 44m
Deal found 8/3![Delta logo]()
$1,093
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:20 pm -
1 stop15h 20m
Mon 11/3011:10 pm -
1 stop16h 22m
Deal found 8/6![Delta logo]()
$1,129
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:02 pm -
1 stop14h 13m
Tue 12/111:10 pm -
1 stop19h 07m
Deal found 8/3![Delta logo]()
$1,129
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:07 am -
1 stop24h 18m
Mon 11/3011:55 pm -
1 stop21h 01m
Deal found 8/3![Delta logo]()
$1,129
Last-minute flights from Charlotte to SantiagoDiscover last-minute flight deals from Charlotte to Santiago. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Santiago. Data last updated August 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:43 pm -
2 stops39h 22m
Thu 9/35:00 am -
2 stops35h 46m
Deal found 8/5![Multiple Airlines logo]()
$868
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:45 pm -
2 stops38h 00m
Fri 8/2812:30 am -
2 stops31h 31m
Deal found 8/5![Multiple Airlines logo]()
$679
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:32 am -
2 stops17h 24m
Tue 9/2911:55 pm -
1 stop15h 00m
Deal found 8/5![Multiple Airlines logo]()
$815
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:32 am -
2 stops19h 13m
Sat 9/261:30 am -
2 stops17h 51m
Deal found 8/5![Multiple Airlines logo]()
$707
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:59 pm -
2 stops31h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$859
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
1 stop31h 56m
Tue 10/1312:23 pm -
2 stops50h 24m
Deal found 8/6![Multiple Airlines logo]()
$824
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:59 pm -
2 stops31h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$857
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/303:00 pm -
2 stops30h 36m
Sun 11/2911:10 pm -
1 stop17h 58m
Deal found 8/3![Multiple Airlines logo]()
$860
One-way flights from Charlotte to SantiagoSearch for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/83:31 pm -
2 stops29h 04m
Deal found 8/6![Multiple Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:31 pm -
2 stops29h 04m
Deal found 8/6![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:22 am -
3 stops43h 16m
Deal found 8/6![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:03 pm -
2 stops28h 32m
Deal found 8/8![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:03 pm -
2 stops35h 22m
Deal found 8/5![Multiple Airlines logo]()
$472
Find flight deals from Charlotte to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $679 (Trip.com) |
One-way from | $309 (Kiwi.com) |
Popular in | August |
Cheapest in | November |
Average price | $1,383 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Thu 9/17
9:32 am-5:45 am
2 stops19h 13m
Santiago Arturo Merino Benitez
Sat 9/26
1:30 am-6:21 pm
2 stops17h 51m
$707
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Fri 8/21
8:56 am-4:45 am
2 stops43h 49m
Santiago Arturo Merino Benitez
Sat 8/29
6:40 am-1:13 pm
3 stops30h 33m
$756
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Mon 10/26
1:59 pm-6:55 am
1 stop15h 56m
Santiago Arturo Merino Benitez
Mon 11/9
5:07 am-7:55 pm
2 stops16h 48m
$867
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Fri 11/6
6:00 am-2:48 am
2 stops18h 48m
Santiago Arturo Merino Benitez
Fri 11/13
1:02 am-6:48 pm
2 stops19h 46m
$902
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Sun 11/8
6:00 am-5:46 am
2 stops21h 46m
Santiago Arturo Merino Benitez
Tue 11/17
1:02 am-10:22 am
2 stops35h 20m
$908
Quickest round-trip
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Mon 11/23
2:20 pm-7:40 am
1 stop15h 20m
Santiago Arturo Merino Benitez
Tue 12/1
11:10 pm-1:32 pm
1 stop16h 22m
$994
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Sat 1/16
6:59 pm-6:00 pm
2 stops21h 01m
Santiago Arturo Merino Benitez
Sat 1/23
8:13 am-11:53 pm
2 stops17h 40m
$994
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Mon 9/28
12:00 pm-5:40 am
2 stops16h 40m
Santiago Arturo Merino Benitez
Tue 10/13
8:50 am-11:59 pm
2 stops16h 09m
$1,084
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Sun 9/27
7:21 pm-7:25 am
1 stop35h 04m
Santiago Arturo Merino Benitez
Thu 12/3
11:55 pm-1:39 pm
1 stop15h 44m
$1,093
CharlotteSantiago
CLT Charlotte Douglas - SCL Santiago Arturo Merino Benitez
CLTSCL
Charlotte Douglas
Mon 11/23
2:20 pm-7:40 am
1 stop15h 20m
Santiago Arturo Merino Benitez
Mon 11/30
11:10 pm-1:32 pm
1 stop16h 22m
$1,129
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Charlotte to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Santiago in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charlotte-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Charlotte-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Charlotte-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charlotte-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charlotte to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
CLT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 9, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andAmerican Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Charlotte to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Santiago by cabin class
Find flights from Charlotte to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Santiago flights
Browse other Charlotte and Santiago flight options. Last updated on August 9, 2026.
Other flights from Charlotte
Browse through other flights departing from Charlotte. Flights are based on user searches made on Cheapflights and were last updated on August 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 9, 2026.
Top 3 airlines flying from Charlotte to Santiago
Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$714 | Average$924 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$753 | Average$971 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$754 | Average$1,029 | FlexibilityNo cancel fee | On-timeN/A |