$316+ Cheap flights from Charlotte (CLT) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
Aug 23 — Aug 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Charlotte to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Charlotte to SantiagoExplore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:11 pm
CLT
- SCL
2 stops29h 35m
Multiple Airlines
Thu 9/2411:55 pm
SCL
- CLT
1 stop17h 10m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$784
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:02 pm
CLT
- SCL
2 stops28h 54m
Multiple Airlines
Sun 9/2011:55 pm
SCL
- CLT
1 stop17h 10m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$817
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:56 am
CLT
- SCL
2 stops16h 54m
Multiple Airlines
Sun 8/3012:35 am
SCL
- CLT
1 stop16h 11m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$832
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:43 pm
CLT
- SCL
2 stops28h 07m
Multiple Airlines
Sun 8/3012:35 am
SCL
- CLT
1 stop16h 11m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$844
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:56 am
CLT
- SCL
2 stops20h 18m
Multiple Airlines
Sat 8/2211:00 pm
SCL
- CLT
1 stop17h 46m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$852
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:11 pm
CLT
- SCL
2 stops26h 28m
Multiple Airlines
Wed 11/1111:10 pm
SCL
- CLT
1 stop18h 30m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$855
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:52 pm
CLT
- SCL
2 stops49h 34m
Multiple Airlines
Sat 8/2911:00 pm
SCL
- CLT
1 stop17h 46m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$879
This Copa Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
CLT
- SCL
2 stops23h 10m
Copa Airlines
Tue 11/103:48 am
SCL
- CLT
2 stops32h 16m
Copa Airlines
Deal found 7/20![Copa Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:07 am
CLT
- SCL
2 stops18h 48m
Delta
Mon 11/3011:55 pm
SCL
- CLT
1 stop20h 21m
Delta
Deal found 7/21![Delta logo]()
$904
This Trip.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm
CLT
- SCL
2 stops23h 37m
Multiple Airlines
Sun 9/136:00 am
SCL
- CLT
2 stops35h 05m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$907
This Copa Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am
CLT
- SCL
2 stops17h 22m
Copa Airlines
Sun 11/11:22 am
SCL
- CLT
2 stops34h 42m
Copa Airlines
Deal found 7/19![Copa Airlines logo]()
$908
This oojo deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:45 am
CLT
- SCL
2 stops17h 10m
LATAM Airlines
Mon 11/308:30 am
SCL
- CLT
3 stops28h 34m
LATAM Airlines
Deal found 7/21![LATAM Airlines logo]()
$939
Best flights from Charlotte to SantiagoDiscover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from Charlotte to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:00 am
CLT
- SCL
2 stops15h 36m
Copa Airlines
Fri 11/131:22 am
SCL
- CLT
2 stops34h 42m
Copa Airlines
Deal found 7/18![Copa Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/183:30 pm
CLT
- SCL
1 stop14h 10m
Delta
Thu 1/2811:55 pm
SCL
- CLT
1 stop20h 21m
Delta
Deal found 7/21![Delta logo]()
$904
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/184:45 pm
CLT
- SCL
1 stop14h 05m
United Airlines
Sat 1/3010:45 pm
SCL
- CLT
1 stop14h 07m
United Airlines
Deal found 7/21![United Airlines logo]()
$949
This oojo deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:45 am
CLT
- SCL
2 stops17h 10m
LATAM Airlines
Sat 11/288:25 am
SCL
- CLT
3 stops28h 39m
LATAM Airlines
Deal found 7/23![LATAM Airlines logo]()
$985
This Copa Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am
CLT
- SCL
2 stops23h 10m
Copa Airlines
Tue 11/103:48 am
SCL
- CLT
2 stops32h 16m
Copa Airlines
Deal found 7/20![Copa Airlines logo]()
$902
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:00 am
CLT
- SCL
1 stop18h 50m
Delta
Wed 1/278:30 pm
SCL
- CLT
2 stops16h 34m
Delta
Deal found 7/21![Delta logo]()
$904
This Copa Airlines deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am
CLT
- SCL
2 stops17h 22m
Copa Airlines
Sun 11/11:22 am
SCL
- CLT
2 stops34h 42m
Copa Airlines
Deal found 7/19![Copa Airlines logo]()
$908
This United Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:28 pm
CLT
- SCL
2 stops37h 22m
United Airlines
Sun 12/2010:45 pm
SCL
- CLT
2 stops24h 10m
United Airlines
Deal found 7/18![United Airlines logo]()
$1,040
This oojo deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:40 am
CLT
- SCL
1 stop19h 45m
LATAM Airlines
Tue 9/299:30 am
SCL
- CLT
3 stops26h 41m
LATAM Airlines
Deal found 7/20![LATAM Airlines logo]()
$1,059
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:15 pm
CLT
- SCL
1 stop15h 35m
Delta
Sat 11/288:13 am
SCL
- CLT
2 stops17h 40m
Delta
Deal found 7/23![Delta logo]()
$994
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
CLT
- SCL
2 stops16h 39m
Copa Airlines
Fri 9/2512:22 pm
SCL
- CLT
2 stops46h 22m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$1,090
Last-minute flights from Charlotte to SantiagoDiscover last-minute flight deals from Charlotte to Santiago. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Santiago. Data last updated July 24, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:59 pm
CLT
- SCL
2 stops31h 01m
Multiple Airlines
Mon 8/311:00 pm
SCL
- CLT
1 stop18h 12m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$1,109
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:02 pm
CLT
- SCL
2 stops41h 33m
Multiple Airlines
Mon 8/311:00 pm
SCL
- CLT
1 stop18h 12m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$1,121
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:02 pm
CLT
- SCL
2 stops33h 53m
Multiple Airlines
Wed 8/511:00 pm
SCL
- CLT
1 stop18h 12m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$963
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:24 pm
CLT
- SCL
2 stops37h 26m
Multiple Airlines
Mon 8/248:40 pm
SCL
- CLT
1 stop12h 12m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$1,032
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:43 pm
CLT
- SCL
2 stops28h 07m
Multiple Airlines
Sun 8/3012:35 am
SCL
- CLT
1 stop16h 11m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$844
This Kiwi.com deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:24 pm
CLT
- SCL
2 stops16h 50m
Multiple Airlines
Sun 8/1610:25 am
SCL
- CLT
1 stop30h 47m
Multiple Airlines
Deal found 7/18![Multiple Airlines logo]()
$1,029
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:56 am
CLT
- SCL
2 stops18h 04m
Multiple Airlines
Mon 8/248:40 pm
SCL
- CLT
1 stop12h 12m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$1,012
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:56 am
CLT
- SCL
2 stops20h 18m
Multiple Airlines
Sat 8/2211:00 pm
SCL
- CLT
1 stop17h 46m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$852
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:52 pm
CLT
- SCL
2 stops49h 34m
Multiple Airlines
Sat 8/2911:00 pm
SCL
- CLT
1 stop17h 46m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$879
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:56 am
CLT
- SCL
2 stops16h 54m
Multiple Airlines
Sun 8/3012:35 am
SCL
- CLT
1 stop16h 11m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$832
One-way flights from Charlotte to SantiagoSearch for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from Charlotte to Santiago. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:43 pm
CLT
- SCL
2 stops28h 07m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:43 pm
CLT
- SCL
2 stops49h 00m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:31 pm
CLT
- SCL
2 stops34h 04m
Multiple Airlines
Deal found 7/19![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:33 pm
CLT
- SCL
2 stops37h 23m
Multiple Airlines
Deal found 7/20![Multiple Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:43 pm
CLT
- SCL
2 stops28h 07m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:36 am
CLT
- SCL
2 stops18h 24m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:43 pm
CLT
- SCL
2 stops29h 17m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$402
Find flight deals from Charlotte to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $784 (Kiwi.com) |
One-way from | $316 (Kiwi.com) |
Popular in | August |
Cheapest in | November |
Average price | $1,304 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Fri 11/6
6:00 am-11:36 pm
2 stops15h 36m
Santiago Arturo Merino Benitez
Fri 11/13
1:22 am-10:04 am
2 stops34h 42m
$902
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Sat 10/24
6:00 am-6:10 am
2 stops23h 10m
Santiago Arturo Merino Benitez
Tue 11/10
3:48 am-10:04 am
2 stops32h 16m
$902
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Mon 1/18
3:30 pm-7:40 am
1 stop14h 10m
Santiago Arturo Merino Benitez
Thu 1/28
11:55 pm-6:16 pm
1 stop20h 21m
$904
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Tue 1/19
10:00 am-6:50 am
1 stop18h 50m
Santiago Arturo Merino Benitez
Wed 1/27
8:30 pm-11:04 am
2 stops16h 34m
$904
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Thu 10/22
6:00 am-12:22 am
2 stops17h 22m
Santiago Arturo Merino Benitez
Sun 11/1
1:22 am-10:04 am
2 stops34h 42m
$908
Quickest round-trip
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Mon 1/18
4:45 pm-8:50 am
1 stop14h 05m
Santiago Arturo Merino Benitez
Sat 1/30
10:45 pm-10:52 am
1 stop14h 07m
$949
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Sat 11/21
11:45 am-6:55 am
2 stops17h 10m
Santiago Arturo Merino Benitez
Sat 11/28
8:25 am-11:04 am
3 stops28h 39m
$985
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Sat 11/21
1:15 pm-6:50 am
1 stop15h 35m
Santiago Arturo Merino Benitez
Sat 11/28
8:13 am-11:53 pm
2 stops17h 40m
$994
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Sat 12/12
5:28 pm-8:50 am
2 stops37h 22m
Santiago Arturo Merino Benitez
Sun 12/20
10:45 pm-8:55 pm
2 stops24h 10m
$1,040
CharlotteSantiago
CLT - SCL
CLTSCL
Charlotte Douglas
Wed 9/16
10:40 am-7:25 am
1 stop19h 45m
Santiago Arturo Merino Benitez
Tue 9/29
9:30 am-11:11 am
3 stops26h 41m
$1,059
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Charlotte to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Santiago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charlotte-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Charlotte-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Charlotte-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charlotte-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charlotte to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
CLT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 24, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andAmerican Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Charlotte
Popular flights
Santiago flight routes
Alternative routes for Charlotte to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Santiago by cabin class
Find flights from Charlotte to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Santiago flights
Browse other Charlotte and Santiago flight options. Last updated on July 24, 2026.
Other flights from Charlotte
Browse through other flights departing from Charlotte. Flights are based on user searches made on Cheapflights and were last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 24, 2026.
Top 3 airlines flying from Charlotte to Santiago
Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$714 | Average$924 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$753 | Average$971 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$754 | Average$1,029 | FlexibilityNo cancel fee | On-timeN/A |