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$295+ Cheap flights from Charlotte (CLT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/24. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — SCL
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Charlotte to Santiago

Cheapest flights from Charlotte to Santiago
Explore the most affordable flight options available from Charlotte to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This eDestinos deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:58 pm
CLT
-
SCL
3 stops34h 57m
Multiple Airlines
Tue 5/198:20 pm
SCL
-
CLT
2 stops44h 53m
Multiple Airlines
Deal found 4/19$696
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:12 am
CLT
-
SCL
3 stops30h 18m
Multiple Airlines
Wed 7/158:20 pm
SCL
-
CLT
3 stops19h 51m
Multiple Airlines
Deal found 4/20$705
This Mytrip deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:00 am
CLT
-
SCL
3 stops35h 11m
Multiple Airlines
Mon 6/83:20 pm
SCL
-
CLT
2 stops32h 20m
Multiple Airlines
Deal found 4/19$737
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:56 pm
CLT
-
SCL
1 stop12h 39m
Multiple Airlines
Tue 9/13:35 am
SCL
-
CLT
2 stops33h 55m
Multiple Airlines
Deal found 4/19$755
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:34 pm
CLT
-
SCL
2 stops18h 51m
Multiple Airlines
Tue 9/13:35 am
SCL
-
CLT
2 stops37h 39m
Multiple Airlines
Deal found 4/22$758
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:12 am
CLT
-
SCL
3 stops30h 18m
Multiple Airlines
Tue 5/193:20 pm
SCL
-
CLT
2 stops32h 20m
Multiple Airlines
Deal found 4/22$776
This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:07 pm
CLT
-
SCL
3 stops30h 54m
Multiple Airlines
Sun 5/243:20 pm
SCL
-
CLT
2 stops20h 23m
Multiple Airlines
Deal found 4/20$781
This FlightHub deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:00 am
CLT
-
SCL
1 stop20h 25m
LATAM Airlines
Wed 9/210:55 pm
SCL
-
CLT
1 stop14h 57m
LATAM Airlines
Deal found 4/19$782
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:33 pm
CLT
-
SCL
1 stop35h 02m
Multiple Airlines
Tue 7/75:00 am
SCL
-
CLT
2 stops36h 14m
Multiple Airlines
Deal found 4/22$783

Find flight deals from Charlotte to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$696
(eDestinos)

One-way from

$295
(Kiwi.com)

Popular in

April

Cheapest in

November

Average price

$1,091
Provider with most accurate pricing for Charlotte Douglas-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Santiago Arturo Merino Benitez flights.
Search Deals
From Charlotte Douglas to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Charlotte Douglas to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($94 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Charlotte to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 5/12

7:12 am-1:30 pm

3 stops30h 18m

Santiago Arturo Merino Benitez

Tue 5/19

3:20 pm-11:40 pm

2 stops32h 20m

$776

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 8/25

2:20 pm-6:55 am

2 stops16h 35m

Santiago Arturo Merino Benitez

Wed 9/2

12:40 am-6:17 pm

2 stops17h 37m

$824

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Mon 5/11

12:48 pm-1:30 pm

3 stops24h 42m

Santiago Arturo Merino Benitez

Wed 5/13

3:20 pm-11:43 am

2 stops20h 23m

$880

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 6/10

3:35 pm-2:35 am

3 stops35h 00m

Santiago Arturo Merino Benitez

Wed 6/17

3:20 pm-11:12 pm

2 stops31h 52m

$918

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Fri 5/22

6:00 am-4:17 am

2 stops22h 17m

Santiago Arturo Merino Benitez

Mon 5/25

3:20 pm-11:40 pm

2 stops32h 20m

$929

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Tue 8/4

7:44 pm-10:43 pm

2 stops26h 59m

Santiago Arturo Merino Benitez

Mon 8/31

11:22 am-9:42 am

2 stops22h 20m

$978

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 6/10

9:57 am-6:25 am

1 stop20h 28m

Santiago Arturo Merino Benitez

Wed 6/17

10:55 pm-6:46 pm

1 stop19h 51m

$1,097

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Fri 5/29

9:45 am-6:25 am

1 stop20h 40m

Santiago Arturo Merino Benitez

Sun 6/7

10:55 pm-6:46 pm

1 stop19h 51m

$1,133
Quickest round-trip

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 10/14

4:30 pm-6:55 am

2 stops13h 25m

Santiago Arturo Merino Benitez

Sun 10/18

10:55 pm-1:54 pm

1 stop15h 59m

$1,138
Cheapest one-way

CharlotteSantiago

CLT - SCL

CLTSCL

Charlotte Douglas

Wed 6/24

5:45 am-1:30 pm

2 stops31h 45m

$295

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/19

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Charlotte to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Santiago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charlotte-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charlotte-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charlotte-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charlotte-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charlotte to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Santiago

What is the cheapest month to book a flight from Charlotte to Santiago?

Currently, November is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $753). Flying from Charlotte to Santiago in April is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Charlotte to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 23, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andAmerican Airlines from Charlotte to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,437 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,437 reviews
Delta
7.9
Good
8,437 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,912 reviews
Delta
7.9
Good
8,437 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,655 reviews
Delta
7.9
Good
8,437 reviews

Entertainment

7.8

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charlotte to Santiago?

    Airlines like LATAM Airlines fly from Charlotte to Santiago in about 16h 35m. The time it takes to get you to your destination can typically vary by up to . The distance from Charlotte to Santiago is about 4783 mi.

  • What are the cheapest airlines flying from Charlotte to Santiago round-trip?

    Cheapflights users have booked flights from Charlotte to Santiago round-trip from $714. Other airlines that can offer you cheap pricing are Delta, from $714, and LATAM Airlines, from $753. American Airlines is currently priced 22% below the average price you’ll pay for this route.

  • Can I find deals for flights from Charlotte to Santiago that include hotel bookings?

    Yes. In addition to deals on Charlotte to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Santiago.

  • Can I find deals for business class flights from Charlotte to Santiago?

    Yes. Cheapflights offers flight deals from Charlotte to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Santiago?

    Currently, November is the cheapest month in which you can book a flight from Charlotte to Santiago (average of $753). Flying from Charlotte to Santiago in April is currently the most expensive (average of $1,091). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charlotte to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Raleigh to Santiago flights
Norfolk to Santiago flights
Knoxville to Santiago flights

Top 3 airlines flying from Charlotte to Santiago

Discover the top 3 airlines that operate flights from Charlotte to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$714Average$924FlexibilityNo cancel feeOn-time71%
DeltaCheapest$714Average$960FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$753Average$873FlexibilityNo cancel feeOn-time81%

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