$130+ Cheap flights from Charlotte (CLT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — BOG
Aug 17 — Aug 241
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to South America
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Cheapest flights from Charlotte to South AmericaExplore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
Explore the most affordable flight options available from Charlotte to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2026.
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/129:55 pm
CLT
- CTG
1 stop15h 40m
American Airlines
Wed 9/161:35 pm
CTG
- CLT
1 stop9h 19m
American Airlines
Deal found 7/14![American Airlines logo]()
$313
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:05 am
CLT
- CTG
1 stop8h 10m
American Airlines
Wed 8/263:15 pm
CTG
- CLT
1 stop16h 25m
American Airlines
Deal found 7/13![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:30 pm
CLT
- CTG
1 stop16h 05m
American Airlines
Wed 9/23:15 pm
CTG
- CLT
1 stop16h 25m
American Airlines
Deal found 7/16![American Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:50 pm
CLT
- CTG
1 stop14h 45m
American Airlines
Sat 9/261:35 pm
CTG
- CLT
1 stop21h 35m
American Airlines
Deal found 7/15![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:48 pm
CLT
- CTG
1 stop17h 47m
American Airlines
Sat 11/74:15 pm
CTG
- CLT
1 stop7h 33m
American Airlines
Deal found 7/14![American Airlines logo]()
$323
This Cheapflightsfares deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:50 am
CLT
- MDE
1 stop8h 40m
JetBlue
Sat 10/241:30 pm
MDE
- CLT
1 stop8h 35m
JetBlue
Deal found 7/14![JetBlue logo]()
$364
This KAYAK deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:50 am
CLT
- CTG
1 stop5h 40m
JetBlue
Sat 10/2412:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 7/14![JetBlue logo]()
$375
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Thu 9/312:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 7/13![JetBlue logo]()
$377
This Cheapflightsfares deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:30 am
CLT
- GYE
1 stop8h 44m
JetBlue
Sun 10/412:30 pm
GYE
- CLT
1 stop9h 50m
JetBlue
Deal found 7/13![JetBlue logo]()
$400
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2510:21 am
CLT
- CTG
2 stops28h 29m
United Airlines
Thu 12/312:20 pm
CTG
- CLT
2 stops19h 39m
United Airlines
Deal found 7/17![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am
CLT
- GYE
1 stop8h 29m
American Airlines
Tue 10/272:29 pm
GYE
- CLT
1 stop16h 56m
American Airlines
Deal found 7/15![American Airlines logo]()
$405
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Wed 8/2612:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/14![JetBlue logo]()
$414
Best flights from Charlotte to South AmericaDiscover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
Discover carefully curated flight deals from Charlotte to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 18, 2026.
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Wed 8/2612:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/14![JetBlue logo]()
$414
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:00 am
CLT
- CTG
2 stops17h 00m
United Airlines
Thu 9/249:45 am
CTG
- CLT
2 stops46h 21m
United Airlines
Deal found 7/17![United Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am
CLT
- GYE
1 stop8h 29m
American Airlines
Tue 10/272:29 pm
GYE
- CLT
1 stop16h 56m
American Airlines
Deal found 7/18![American Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:46 am
CLT
- BOG
1 stop9h 14m
Multiple Airlines
Sun 8/239:05 am
BOG
- CLT
1 stop10h 38m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:55 am
CLT
- MDE
2 stops15h 15m
Delta
Fri 10/166:20 am
MDE
- CLT
2 stops14h 33m
Delta
Deal found 7/17![Delta logo]()
$522
This Copa Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:50 pm
CLT
- CTG
2 stops23h 05m
Copa Airlines
Sat 10/313:05 pm
CTG
- CLT
2 stops18h 59m
Copa Airlines
Deal found 7/14![Copa Airlines logo]()
$544
This GOL deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 pm
CLT
- GIG
2 stops36h 10m
GOL
Fri 9/410:45 pm
GIG
- CLT
2 stops36h 10m
GOL
Deal found 7/17![GOL logo]()
$745
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:30 am
CLT
- GYE
1 stop8h 44m
JetBlue
Tue 9/2212:30 pm
GYE
- CLT
1 stop9h 50m
JetBlue
Deal found 7/13![JetBlue logo]()
$454
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:00 am
CLT
- CTG
2 stops17h 00m
United Airlines
Thu 9/103:05 pm
CTG
- CLT
2 stops28h 39m
United Airlines
Deal found 7/13![United Airlines logo]()
$458
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Fri 9/412:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/14![JetBlue logo]()
$457
This oojo deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:23 pm
CLT
- SCL
1 stop16h 02m
LATAM Airlines
Sun 9/205:50 pm
SCL
- CLT
2 stops20h 52m
LATAM Airlines
Deal found 7/13![LATAM Airlines logo]()
$1,007
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
CLT
- CTG
2 stops17h 00m
United Airlines
Mon 8/313:05 pm
CTG
- CLT
2 stops42h 49m
United Airlines
Deal found 7/16![United Airlines logo]()
$478
This Expedia deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:30 am
CLT
- GYE
1 stop9h 52m
Multiple Airlines
Thu 9/39:00 am
GYE
- CLT
2 stops32h 20m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
CLT
- MDE
2 stops16h 10m
Delta
Wed 9/165:50 am
MDE
- CLT
2 stops17h 09m
Delta
Deal found 7/17![Delta logo]()
$551
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:00 am
CLT
- MDE
1 stop6h 25m
JetBlue
Wed 9/21:30 pm
MDE
- CLT
1 stop8h 50m
JetBlue
Deal found 7/13![JetBlue logo]()
$472
This Copa Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
CLT
- MDE
2 stops27h 15m
Copa Airlines
Sat 9/263:10 pm
MDE
- CLT
2 stops17h 34m
Copa Airlines
Deal found 7/16![Copa Airlines logo]()
$588
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:45 am
CLT
- MDE
1 stop10h 25m
United Airlines
Tue 9/229:45 am
MDE
- CLT
1 stop24h 09m
United Airlines
Deal found 7/17![United Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:30 am
CLT
- BOG
1 stop9h 10m
Delta
Sun 9/202:55 pm
BOG
- CLT
1 stop16h 54m
Delta
Deal found 7/13![Delta logo]()
$575
This Delta deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:30 am
CLT
- BOG
2 stops13h 20m
Delta
Fri 10/309:00 am
BOG
- CLT
1 stop10h 14m
Delta
Deal found 7/15![Delta logo]()
$590
This United Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:55 pm
CLT
- MDE
2 stops26h 15m
United Airlines
Thu 9/249:45 am
MDE
- CLT
1 stop29h 21m
United Airlines
Deal found 7/17![United Airlines logo]()
$539
This JetBlue deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:30 am
CLT
- CTG
1 stop6h 22m
JetBlue
Thu 9/242:00 pm
CTG
- CLT
1 stop8h 20m
JetBlue
Deal found 7/15![JetBlue logo]()
$549
This Trip.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:56 am
CLT
- SCL
2 stops38h 24m
Multiple Airlines
Sat 9/191:30 am
SCL
- CLT
2 stops40h 08m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$680
This Delta deal was found by Cheapflights users on 7/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:30 am
CLT
- BOG
2 stops15h 40m
Delta
Fri 10/232:55 pm
BOG
- CLT
1 stop18h 15m
Delta
Deal found 7/18![Delta logo]()
$590
This Copa Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am
CLT
- GYE
2 stops17h 55m
Copa Airlines
Tue 12/12:45 pm
GYE
- CLT
2 stops18h 59m
Copa Airlines
Deal found 7/15![Copa Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:55 pm
CLT
- MDE
2 stops26h 15m
United Airlines
Fri 9/259:45 am
MDE
- CLT
1 stop11h 14m
United Airlines
Deal found 7/16![United Airlines logo]()
$554
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- MDE
1 stop8h 55m
JetBlue
Wed 8/191:30 pm
MDE
- CLT
1 stop8h 50m
JetBlue
Deal found 7/14![JetBlue logo]()
$562
This GOL deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:40 pm
CLT
- GRU
2 stops27h 10m
GOL
Wed 11/256:00 am
GRU
- CLT
2 stops17h 10m
GOL
Deal found 7/13![GOL logo]()
$856
This Copa Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:50 pm
CLT
- GYE
2 stops15h 43m
Copa Airlines
Tue 10/276:01 am
GYE
- CLT
2 stops11h 45m
Copa Airlines
Deal found 7/15![Copa Airlines logo]()
$719
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:30 am
CLT
- BOG
1 stop9h 10m
Delta
Wed 8/195:00 am
BOG
- CLT
2 stops17h 57m
Delta
Deal found 7/13![Delta logo]()
$615
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:00 am
CLT
- CTG
2 stops17h 00m
United Airlines
Tue 9/89:45 am
CTG
- CLT
2 stops24h 09m
United Airlines
Deal found 7/13![United Airlines logo]()
$567
Last-minute flights from Charlotte to South AmericaDiscover last-minute flight deals from Charlotte to South America. Data last updated July 18, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to South America. Data last updated July 18, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Wed 8/2612:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/14![JetBlue logo]()
$414
This Flighttix deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Sat 8/2212:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/15![JetBlue logo]()
$420
This Justfly.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Tue 8/1812:35 pm
CTG
- CLT
1 stop9h 45m
JetBlue
Deal found 7/15![JetBlue logo]()
$457
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:05 am
CLT
- CTG
1 stop8h 10m
American Airlines
Wed 8/263:15 pm
CTG
- CLT
1 stop16h 25m
American Airlines
Deal found 7/13![American Airlines logo]()
$315
This Cheapflightsfares deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:30 am
CLT
- MDE
1 stop8h 55m
JetBlue
Wed 8/191:30 pm
MDE
- CLT
1 stop8h 50m
JetBlue
Deal found 7/14![JetBlue logo]()
$491
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:30 pm
CLT
- CTG
1 stop16h 05m
American Airlines
Tue 8/253:15 pm
CTG
- CLT
1 stop7h 44m
American Airlines
Deal found 7/14![American Airlines logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:46 am
CLT
- BOG
1 stop9h 14m
Multiple Airlines
Sun 8/239:05 am
BOG
- CLT
1 stop10h 38m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$519
This Cheapflightsfares deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:30 am
CLT
- GYE
1 stop9h 52m
JetBlue
Wed 9/3012:30 pm
GYE
- CLT
1 stop9h 50m
JetBlue
Deal found 7/13![JetBlue logo]()
$420
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
CLT
- CTG
2 stops17h 00m
United Airlines
Mon 8/313:05 pm
CTG
- CLT
2 stops42h 49m
United Airlines
Deal found 7/15![United Airlines logo]()
$478
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:30 pm
CLT
- CTG
1 stop16h 05m
American Airlines
Wed 9/23:15 pm
CTG
- CLT
1 stop16h 25m
American Airlines
Deal found 7/16![American Airlines logo]()
$317
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/306:30 am
CLT
- CTG
1 stop6h 05m
JetBlue
Thu 9/312:35 pm
CTG
- CLT
1 stop7h 34m
JetBlue
Deal found 7/13![JetBlue logo]()
$377
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/319:00 am
CLT
- MDE
1 stop6h 25m
JetBlue
Wed 9/21:30 pm
MDE
- CLT
1 stop8h 50m
JetBlue
Deal found 7/13![JetBlue logo]()
$472
One-way flights from Charlotte to South AmericaSearch for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
Search for one-way flight options from Charlotte to South America. Find affordable one-way fares based on user searches. Data last updated July 18, 2026.
This American Airlines deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:24 pm
CLT
- CTG
1 stop17h 06m
American Airlines
Deal found 7/17![American Airlines logo]()
$130
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
CLT
- CTG
2 stops9h 15m
American Airlines
Deal found 7/14![American Airlines logo]()
$132
This SmartFares deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:30 am
CLT
- GYE
1 stop9h 52m
JetBlue
Deal found 7/15![JetBlue logo]()
$170
This Cheapflightsfares deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:00 am
CLT
- GYE
1 stop7h 22m
JetBlue
Deal found 7/13![JetBlue logo]()
$173
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:18 pm
CLT
- GYE
1 stop10h 27m
American Airlines
Deal found 7/16![American Airlines logo]()
$176
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:10 am
CLT
- GYE
2 stops14h 29m
American Airlines
Deal found 7/15![American Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:38 pm
CLT
- GYE
3 stops46h 44m
Multiple Airlines
Deal found 7/17![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:28 pm
CLT
- GYE
2 stops28h 02m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$199
This SmartFares deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:00 am
CLT
- GYE
1 stop7h 22m
JetBlue
Deal found 7/15![JetBlue logo]()
$201
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:35 am
CLT
- GYE
2 stops13h 35m
American Airlines
Deal found 7/15![American Airlines logo]()
$202
This Cheapflightsfares deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:30 am
CLT
- GYE
1 stop8h 44m
JetBlue
Deal found 7/13![JetBlue logo]()
$203
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:45 pm
CLT
- CTG
1 stop16h 29m
American Airlines
Deal found 7/15![American Airlines logo]()
$232
Find flight deals from Charlotte to South America
Keep the following information in mind while searching for Charlotte to South America flight deals. Data was last updated July 18, 2026.
Round-trip from | $313 (American Airlines) |
|---|---|
One-way from | $130 (American Airlines) |
Popular in | January |
Cheapest in | February |
Average price | $720 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
Use the filters below to find and compare flights from Charlotte to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Wed 8/12
6:30 am-11:35 am
1 stop6h 05m
Cartagena Rafael Nunez
Wed 8/26
12:35 pm-11:20 pm
1 stop9h 45m
$414
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Mon 9/21
7:00 am-11:00 pm
2 stops17h 00m
Cartagena Rafael Nunez
Thu 9/24
9:45 am-9:06 am
2 stops46h 21m
$443
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Mon 9/21
7:30 am-3:14 pm
1 stop8h 44m
Guayaquil Jose Joaquin de Olmedo
Tue 9/22
12:30 pm-11:20 pm
1 stop9h 50m
$454
CharlotteGuayaquil
CLT - GYE
CLTGYE
Charlotte Douglas
Mon 10/19
6:00 am-1:29 pm
1 stop8h 29m
Guayaquil Jose Joaquin de Olmedo
Tue 10/27
2:29 pm-8:25 am
1 stop16h 56m
$457
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Fri 8/28
6:30 am-11:35 am
1 stop6h 05m
Cartagena Rafael Nunez
Fri 9/4
12:35 pm-11:20 pm
1 stop9h 45m
$457
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Thu 9/3
7:00 am-11:00 pm
2 stops17h 00m
Cartagena Rafael Nunez
Thu 9/10
3:05 pm-8:44 pm
2 stops28h 39m
$458
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Mon 8/31
9:00 am-2:25 pm
1 stop6h 25m
Medellín Jose Maria Cordova Intl
Wed 9/2
1:30 pm-11:20 pm
1 stop8h 50m
$472
CharlotteCartagena
CLT - CTG
CLTCTG
Charlotte Douglas
Wed 8/26
7:00 am-11:00 pm
2 stops17h 00m
Cartagena Rafael Nunez
Mon 8/31
3:05 pm-10:54 am
2 stops42h 49m
$478
CharlotteMedellín
CLT - MDE
CLTMDE
Charlotte Douglas
Tue 9/8
11:45 am-9:10 pm
1 stop10h 25m
Medellín Jose Maria Cordova Intl
Tue 9/22
9:45 am-10:54 am
1 stop24h 09m
$498
CharlotteBogotá
CLT - BOG
CLTBOG
Charlotte Douglas
Fri 8/21
9:46 am-6:00 pm
1 stop9h 14m
Bogotá El Dorado
Sun 8/23
9:05 am-8:43 pm
1 stop10h 38m
$519
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Charlotte to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charlotte with our price prediction graph.
CLT-CTG
CLT-GYE
CLT-BOG
CLT-MDE
CLT-GIG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to South America
CLT-0SA
CLT-CTG
CLT-GYE
CLT-BOG
CLT-MDE
What is the cheapest month to book a flight from Charlotte to South America?
Currently, February is the cheapest month in which you can book a flight from Charlotte to South America (average of $539). Flying from Charlotte to South America in December is currently the most expensive (average of $914). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Charlotte to South America?
To ensure you get the cheapest price possible for a flight from Charlotte to South America, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 18, 2026.
Read reviews from past customers who have flown Delta,LATAM Airlines, andGOL from Charlotte to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.8
Crew
8.5
Food
7.2
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charlotte to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charlotte to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to South America by cabin class
Find flights from Charlotte to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and South America flights
Browse other Charlotte and South America flight options. Last updated on July 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charlotte to South America flights
Consider these flights traveling from Charlotte to South America.
Top 5 airlines flying from Charlotte to South America
Discover the top 5 airlines that operate flights from Charlotte to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$978 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$430 | Average$598 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$439 | Average$1,058 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$503 | Average$767 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$670 | Average$964 | FlexibilityNo cancel fee | On-time74% |