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$388+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$966
(Mytrip)

One-way from

$388
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$862
From Charleston to Santiago Arturo Merino Benitez
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One-way flight from Charleston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 13% potential increase in price ($123 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/167:00 amCHS - SCL
3 stops21h 01mMultiple Airlines
Sat 8/239:06 pmSCL - CHS
2 stops22h 06mMultiple Airlines
Deal found 7/2$966
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1610:56 amCHS - SCL
1 stop19h 59mAmerican Airlines
Mon 8/259:55 pmSCL - CHS
1 stop21h 05mAmerican Airlines
Deal found 7/2$994
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/162:55 pmCHS - SCL
1 stop16h 05mDelta
Tue 8/198:40 pmSCL - CHS
1 stop22h 14mDelta
Deal found 6/30$1,044
This Expedia deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/154:44 pmCHS - SCL
2 stops14h 06mLATAM Airlines
Fri 8/228:40 amSCL - CHS
3 stops27h 10mLATAM Airlines
Deal found 6/30$1,184
This Copa Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1510:00 amCHS - SCL
2 stops19h 02mCopa Airlines
Thu 8/212:26 amSCL - CHS
2 stops31h 47mCopa Airlines
Deal found 6/30$1,224

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 8/16

7:00 am-4:01 am

3 stops21h 01m

Santiago Arturo Merino Benitez

Sat 8/23

9:06 pm-7:12 pm

2 stops22h 06m

$966

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 8/16

10:56 am-6:55 am

1 stop19h 59m

Santiago Arturo Merino Benitez

Mon 8/25

9:55 pm-7:00 pm

1 stop21h 05m

$994

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 8/16

2:55 pm-7:00 am

1 stop16h 05m

Santiago Arturo Merino Benitez

Tue 8/19

8:40 pm-6:54 pm

1 stop22h 14m

$1,044

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Fri 8/15

4:44 pm-6:50 am

2 stops14h 06m

Santiago Arturo Merino Benitez

Fri 8/22

8:40 am-11:50 am

3 stops27h 10m

$1,184

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Fri 8/15

10:00 am-5:02 am

2 stops19h 02m

Santiago Arturo Merino Benitez

Thu 8/21

2:26 am-10:13 am

2 stops31h 47m

$1,224

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 8/6

2:48 pm-7:24 pm

2 stops52h 36m

$388

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 8/6

7:00 am-6:45 am

1 stop23h 45m

$470

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago

What is the cheapest month to book a flight from Charleston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Charleston to Santiago (average of $752). Flying from Charleston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SCL?

Find hourly flight availability from Charleston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

It’s optimal to fly from Charleston to Santiago at noon. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 3, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and Copa Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,805 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,467 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $994, American Airlines will fly you from Charleston to Santiago and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and LATAM Airlines - these airlines can fly you to your destination from $1,044 and $1,184, respectively.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Charleston to Santiago (average of $752). Flying from Charleston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Santiago flights
Greenville to Santiago flights
Savannah to Santiago flights
Charlotte to Easter Island flights
Myrtle Beach to Santiago flights

Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$532Average$852FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$603Average$878FlexibilityNo cancel feeOn-time81%

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