$207+ Cheap flights from Charleston (CHS) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BOG
Jun 25 — Jul 21
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to South America
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Cheapest flights from Charleston to South AmericaExplore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
Explore the most affordable flight options available from Charleston to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 26, 2026.
This Avianca deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:50 am
CHS
- UIO
1 stop20h 05m
Multiple Airlines
Sun 11/155:20 pm
UIO
- CHS
1 stop16h 39m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:09 pm
CHS
- CTG
1 stop17h 26m
American Airlines
Fri 6/121:35 pm
CTG
- CHS
1 stop9h 24m
American Airlines
Deal found 5/22![American Airlines logo]()
$468
This Avianca deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:25 pm
CHS
- UIO
1 stop11h 10m
Multiple Airlines
Sun 10/115:25 pm
UIO
- CHS
1 stop15h 50m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:43 am
CHS
- CTG
2 stops13h 52m
Delta
Sat 6/132:30 pm
CTG
- CHS
1 stop8h 27m
Delta
Deal found 5/23![Delta logo]()
$506
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
CHS
- CTG
1 stop9h 05m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$517
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:13 pm
CHS
- CTG
1 stop17h 22m
American Airlines
Fri 7/103:17 pm
CTG
- CHS
1 stop7h 42m
American Airlines
Deal found 5/21![American Airlines logo]()
$523
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:59 pm
CHS
- CTG
1 stop18h 16m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$524
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:59 pm
CHS
- CTG
2 stops28h 36m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$530
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
CHS
- CTG
1 stop7h 35m
American Airlines
Fri 8/283:17 pm
CTG
- CHS
1 stop7h 49m
American Airlines
Deal found 5/22![American Airlines logo]()
$534
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
CHS
- CTG
1 stop9h 05m
Delta
Sun 6/145:30 am
CTG
- CHS
2 stops18h 06m
Delta
Deal found 5/24![Delta logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:34 pm
CHS
- BOG
1 stop11h 11m
Multiple Airlines
Wed 7/14:05 pm
BOG
- CHS
1 stop15h 33m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$550
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:53 pm
CHS
- BOG
1 stop12h 52m
Multiple Airlines
Thu 7/164:05 pm
BOG
- CHS
1 stop15h 40m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$568
Best flights from Charleston to South AmericaDiscover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
Discover carefully curated flight deals from Charleston to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 26, 2026.
This Avianca deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:25 pm
CHS
- UIO
1 stop11h 10m
Multiple Airlines
Sun 10/115:25 pm
UIO
- CHS
1 stop15h 50m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:43 am
CHS
- CTG
2 stops13h 52m
Delta
Sat 6/132:30 pm
CTG
- CHS
1 stop8h 27m
Delta
Deal found 5/23![Delta logo]()
$506
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:50 pm
CHS
- CTG
2 stops17h 45m
American Airlines
Sat 6/131:35 pm
CTG
- CHS
2 stops20h 26m
American Airlines
Deal found 5/23![American Airlines logo]()
$542
This KAYAK deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:20 pm
CHS
- CTG
1 stop19h 20m
JetBlue
Sat 6/132:05 pm
CTG
- CHS
1 stop24h 52m
JetBlue
Deal found 5/23![JetBlue logo]()
$585
This United Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
CHS
- MDE
1 stop15h 10m
United Airlines
Mon 8/319:45 am
MDE
- CHS
1 stop11h 26m
United Airlines
Deal found 5/24![United Airlines logo]()
$601
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:23 am
CHS
- BOG
1 stop8h 52m
LATAM Airlines
Wed 7/18:40 am
BOG
- CHS
2 stops24h 20m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$616
This Travelocity deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 pm
CHS
- VCP
1 stop20h 45m
Azul
Mon 11/1610:45 pm
VCP
- CHS
1 stop21h 20m
Azul
Deal found 5/23![Azul logo]()
$894
This Avianca deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:25 pm
CHS
- UIO
2 stops12h 30m
Multiple Airlines
Sun 11/155:20 pm
UIO
- CHS
1 stop16h 39m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$525
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:13 pm
CHS
- CTG
1 stop17h 22m
American Airlines
Fri 7/103:17 pm
CTG
- CHS
1 stop18h 05m
American Airlines
Deal found 5/25![American Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:24 pm
CHS
- CTG
1 stop19h 51m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$583
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:20 am
CHS
- BOG
2 stops14h 15m
LATAM Airlines
Thu 7/302:55 pm
BOG
- CHS
1 stop8h 31m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
CHS
- MDE
1 stop15h 10m
United Airlines
Sun 8/309:45 am
MDE
- CHS
1 stop11h 26m
United Airlines
Deal found 5/22![United Airlines logo]()
$621
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:06 am
CHS
- MDE
2 stops13h 45m
American Airlines
Mon 8/2412:30 am
MDE
- CHS
2 stops11h 46m
American Airlines
Deal found 5/22![American Airlines logo]()
$582
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:10 am
CHS
- BOG
2 stops16h 00m
Delta
Mon 7/611:00 am
BOG
- CHS
2 stops11h 24m
Delta
Deal found 5/23![Delta logo]()
$619
This KAYAK deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:51 pm
CHS
- MDE
2 stops26h 19m
Multiple Airlines
Sun 9/139:45 am
MDE
- CHS
2 stops23h 18m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/24:58 pm
CHS
- MDE
2 stops29h 12m
United Airlines
Sun 9/69:45 am
MDE
- CHS
2 stops23h 18m
United Airlines
Deal found 5/21![United Airlines logo]()
$626
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:30 am
CHS
- CTG
1 stop7h 35m
LATAM Airlines
Tue 11/173:25 pm
CTG
- CHS
1 stop8h 31m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:00 am
CHS
- MDE
1 stop15h 16m
American Airlines
Sat 8/16:00 am
MDE
- CHS
2 stops16h 59m
American Airlines
Deal found 5/21![American Airlines logo]()
$582
This BusinessClass deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
CHS
- VCP
2 stops27h 45m
GOL
Wed 8/126:00 pm
VCP
- CHS
2 stops30h 59m
GOL
Deal found 5/24![GOL logo]()
$1,523
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:59 pm
CHS
- BOG
2 stops22h 51m
Delta
Sun 6/2811:00 am
BOG
- CHS
2 stops12h 36m
Delta
Deal found 5/22![Delta logo]()
$639
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
CHS
- CTG
1 stop9h 15m
American Airlines
Mon 8/313:17 pm
CTG
- CHS
2 stops20h 14m
American Airlines
Deal found 5/21![American Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:50 am
CHS
- BOG
1 stop13h 30m
United Airlines
Thu 7/308:30 am
BOG
- CHS
2 stops24h 41m
United Airlines
Deal found 5/25![United Airlines logo]()
$655
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:45 am
CHS
- LIM
2 stops15h 15m
LATAM Airlines
Mon 9/148:15 am
LIM
- CHS
2 stops14h 42m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$714
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:15 am
CHS
- BOG
2 stops14h 55m
Delta
Thu 7/308:40 am
BOG
- CHS
2 stops23h 21m
Delta
Deal found 5/22![Delta logo]()
$659
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:04 am
CHS
- BOG
1 stop11h 13m
American Airlines
Thu 7/306:30 am
BOG
- CHS
1 stop16h 29m
American Airlines
Deal found 5/25![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:30 am
CHS
- UIO
1 stop18h 00m
United Airlines
Mon 11/161:35 am
UIO
- CHS
2 stops16h 10m
United Airlines
Deal found 5/25![United Airlines logo]()
$686
This LATAM Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:55 pm
CHS
- UIO
2 stops11h 03m
LATAM Airlines
Tue 11/177:00 pm
UIO
- CHS
2 stops16h 26m
LATAM Airlines
Deal found 5/22![LATAM Airlines logo]()
$720
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:00 am
CHS
- BOG
2 stops23h 54m
United Airlines
Sat 7/48:30 am
BOG
- CHS
2 stops24h 53m
United Airlines
Deal found 5/23![United Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:50 am
CHS
- UIO
2 stops14h 50m
American Airlines
Mon 10/126:40 am
UIO
- CHS
2 stops16h 15m
American Airlines
Deal found 5/23![American Airlines logo]()
$655
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:17 pm
CHS
- LIM
2 stops15h 43m
LATAM Airlines
Mon 9/148:15 am
LIM
- CHS
2 stops14h 42m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$744
Last-minute flights from Charleston to South AmericaDiscover last-minute flight deals from Charleston to South America. Data last updated May 26, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to South America. Data last updated May 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:09 pm
CHS
- CTG
1 stop17h 26m
American Airlines
Fri 6/121:35 pm
CTG
- CHS
1 stop9h 24m
American Airlines
Deal found 5/22![American Airlines logo]()
$468
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:43 am
CHS
- CTG
2 stops13h 52m
Delta
Sat 6/132:30 pm
CTG
- CHS
1 stop8h 27m
Delta
Deal found 5/23![Delta logo]()
$506
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:09 pm
CHS
- CTG
1 stop19h 04m
American Airlines
Sat 6/131:35 pm
CTG
- CHS
2 stops20h 26m
American Airlines
Deal found 5/23![American Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:59 pm
CHS
- CTG
2 stops28h 36m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$530
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:59 pm
CHS
- CTG
2 stops47h 31m
Delta
Sun 6/145:30 am
CTG
- CHS
2 stops26h 30m
Delta
Deal found 5/24![Delta logo]()
$558
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:59 pm
CHS
- CTG
1 stop18h 16m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$524
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:20 am
CHS
- CTG
2 stops17h 15m
Delta
Sun 6/144:30 am
CTG
- CHS
2 stops19h 06m
Delta
Deal found 5/24![Delta logo]()
$551
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
CHS
- CTG
1 stop9h 05m
Delta
Tue 6/162:30 pm
CTG
- CHS
1 stop17h 30m
Delta
Deal found 5/24![Delta logo]()
$517
This Delta deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:10 am
CHS
- CTG
1 stop9h 05m
Delta
Sun 6/145:30 am
CTG
- CHS
2 stops18h 06m
Delta
Deal found 5/24![Delta logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/244:34 pm
CHS
- BOG
1 stop11h 11m
Multiple Airlines
Wed 7/14:05 pm
BOG
- CHS
1 stop15h 33m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$550
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:23 am
CHS
- BOG
1 stop8h 52m
LATAM Airlines
Wed 7/18:40 am
BOG
- CHS
2 stops24h 20m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$616
This Delta deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:10 am
CHS
- BOG
2 stops14h 55m
Delta
Mon 7/69:00 am
BOG
- CHS
1 stop14h 36m
Delta
Deal found 5/23![Delta logo]()
$619
One-way flights from Charleston to South AmericaSearch for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
Search for one-way flight options from Charleston to South America. Find affordable one-way fares based on user searches. Data last updated May 26, 2026.
This Orbitz deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:00 pm
CHS
- MDE
2 stops19h 10m
JetBlue
Deal found 5/24![JetBlue logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:04 pm
CHS
- CTG
2 stops31h 56m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:04 pm
CHS
- MDE
3 stops51h 45m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:44 pm
CHS
- BOG
1 stop28h 01m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:20 pm
CHS
- BOG
2 stops14h 50m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/303:15 pm
CHS
- BOG
2 stops15h 50m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:00 am
CHS
- UIO
2 stops42h 25m
United Airlines
Deal found 5/22![United Airlines logo]()
$366
This KAYAK deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:40 pm
CHS
- MDE
1 stop20h 45m
JetBlue
Deal found 5/26![JetBlue logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:20 pm
CHS
- MDE
3 stops36h 55m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
CHS
- CTG
1 stop9h 17m
American Airlines
Deal found 5/24![American Airlines logo]()
$403
This Ovago deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:15 am
CHS
- BOG
1 stop13h 05m
Avianca
Deal found 5/25![Avianca logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:04 pm
CHS
- GRU
3 stops47h 01m
Multiple Airlines
Deal found 5/23![Multiple Airlines logo]()
$554
Find flight deals from Charleston to South America
Keep the following information in mind while searching for Charleston to South America flight deals. Data was last updated May 26, 2026.
Round-trip from | $454 (Avianca) |
|---|---|
One-way from | $207 (Orbitz) |
Popular in | May |
Cheapest in | September |
Average price | $954 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
Use the filters below to find and compare flights from Charleston to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonQuito
CHS - UIO
CHSUIO
Charleston
Thu 10/8
8:25 pm-6:35 am
1 stop11h 10m
Quito Mariscal Sucr
Sun 10/11
5:25 pm-10:15 am
1 stop15h 50m
$473
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Sat 6/6
10:43 am-11:35 pm
2 stops13h 52m
Cartagena Rafael Nunez
Sat 6/13
2:30 pm-11:57 pm
1 stop8h 27m
$506
CharlestonQuito
CHS - UIO
CHSUIO
Charleston
Mon 11/9
8:25 pm-8:55 am
2 stops12h 30m
Quito Mariscal Sucr
Sun 11/15
5:20 pm-9:59 am
1 stop16h 39m
$525
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Sat 6/6
7:50 pm-12:35 pm
2 stops17h 45m
Cartagena Rafael Nunez
Sat 6/13
1:35 pm-11:01 am
2 stops20h 26m
$542
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Fri 7/3
8:13 pm-12:35 pm
1 stop17h 22m
Cartagena Rafael Nunez
Fri 7/10
3:17 pm-10:22 am
1 stop18h 05m
$565
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Tue 8/11
11:06 am-11:51 pm
2 stops13h 45m
Medellín Jose Maria Cordova Intl
Mon 8/24
12:30 am-1:16 pm
2 stops11h 46m
$582
CharlestonMedellín
CHS - MDE
CHSMDE
Charleston
Sun 7/19
6:00 am-8:16 pm
1 stop15h 16m
Medellín Jose Maria Cordova Intl
Sat 8/1
6:00 am-11:59 pm
2 stops16h 59m
$582
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Wed 6/10
6:24 pm-1:15 pm
1 stop19h 51m
Cartagena Rafael Nunez
Tue 6/16
2:30 pm-9:00 am
1 stop17h 30m
$583
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Fri 8/28
6:00 am-2:15 pm
1 stop9h 15m
Cartagena Rafael Nunez
Mon 8/31
3:17 pm-12:31 pm
2 stops20h 14m
$583
CharlestonCartagena
CHS - CTG
CHSCTG
Charleston
Sat 6/6
7:20 pm-1:40 pm
1 stop19h 20m
Cartagena Rafael Nunez
Sat 6/13
2:05 pm-3:57 pm
1 stop24h 52m
$585
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from Charleston to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Charleston with our price prediction graph.
CHS-CTG
CHS-BOG
CHS-MDE
CHS-UIO
CHS-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to South America
CHS-0SA
CHS-CTG
CHS-BOG
CHS-MDE
CHS-UIO
What is the cheapest month to book a flight from Charleston to South America?
Currently, September is the cheapest month in which you can book a flight from Charleston to South America (average of $156). Flying from Charleston to South America in May is currently the most expensive (average of $699). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated May 26, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andAmerican Airlines from Charleston to South America have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Entertainment
7.8
Food
7.2
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to South America by cabin class
Find flights from Charleston to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and South America flights
Browse other Charleston and South America flight options. Last updated on May 26, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Charleston to South America flights
Consider these flights traveling from Charleston to South America.
Top 3 airlines flying from Charleston to South America
Discover the top 3 airlines that operate flights from Charleston to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$301 | Average$691 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$493 | Average$730 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$542 | Average$737 | FlexibilityNo cancel fee | On-time81% |