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$975+ Cheap flights from Greenville (GSP) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SCL
Jun 3 — Jun 101
Wed 6/3
Wed 6/10
1 adult, Economy
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Cheap flight deals from Greenville to Santiago

Cheapest flights from Greenville to Santiago
Explore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.

This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:40 pm
GSP
-
SCL
1 stop12h 10m
American Airlines
Fri 8/288:30 pm
SCL
-
GSP
1 stop21h 40m
American Airlines
Deal found 4/30$975
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:12 pm
GSP
-
SCL
2 stops15h 38m
American Airlines
Mon 8/248:30 pm
SCL
-
GSP
2 stops16h 35m
American Airlines
Deal found 4/30$980
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:00 pm
GSP
-
SCL
3 stops25h 25m
LATAM Airlines
Mon 8/2411:00 pm
SCL
-
GSP
2 stops19h 52m
LATAM Airlines
Deal found 4/30$1,012
This KAYAK deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:09 pm
GSP
-
SCL
2 stops16h 51m
LATAM Airlines
Tue 12/16:45 pm
SCL
-
GSP
2 stops16h 40m
LATAM Airlines
Deal found 5/1$1,057
This KAYAK deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2012:00 pm
GSP
-
SCL
3 stops25h 25m
LATAM Airlines
Fri 8/284:10 am
SCL
-
GSP
2 stops19h 28m
LATAM Airlines
Deal found 4/30$1,062
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:03 am
GSP
-
SCL
1 stop19h 32m
Multiple Airlines
Wed 6/311:17 am
SCL
-
GSP
2 stops27h 41m
Multiple Airlines
Deal found 4/29$1,108

Find flight deals from Greenville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 4, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$975
(American Airlines)
Provider with most accurate pricing for Greenville-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santiago Arturo Merino Benitez flights.
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From Greenville to Santiago Arturo Merino Benitez
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Greenville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 8/20

11:15 am-6:50 am

2 stops19h 35m

Santiago Arturo Merino Benitez

Fri 8/28

8:30 pm-3:55 pm

2 stops19h 25m

$1,030

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Sat 8/1

10:03 am-6:00 am

2 stops19h 57m

Santiago Arturo Merino Benitez

Tue 12/1

11:10 pm-10:58 am

1 stop13h 48m

$1,065

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Tue 6/16

12:37 pm-7:05 am

2 stops18h 28m

Santiago Arturo Merino Benitez

Tue 6/23

9:00 pm-7:02 pm

2 stops22h 02m

$1,130

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 10/29

2:25 pm-6:50 am

2 stops15h 25m

Santiago Arturo Merino Benitez

Mon 11/2

8:15 am-10:58 am

2 stops28h 43m

$1,136

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Mon 5/18

10:03 am-5:35 am

1 stop19h 32m

Santiago Arturo Merino Benitez

Fri 6/5

2:22 am-2:58 pm

2 stops36h 36m

$1,148
Quickest round-trip

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Thu 10/29

5:15 pm-7:50 am

1 stop13h 35m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-3:18 pm

1 stop18h 33m

$1,195

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Sorted by cheapest first

Compare providers for flights from Greenville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santiago in May.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Greenville-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Greenville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 4, 2026.
Peruse reviews from past customers who have flown with Delta and LATAM Airlines from Greenville to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,461 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
Delta
7.9
Good
8,461 reviews
Delta
7.9
Good
8,461 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work
LATAM Airlines
7.4
Good
1,915 reviews
Delta
7.9
Good
8,461 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Comfort

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Barney,May 2026

JFK - ATL

Terrible flight. Late, reduced beverage service, lack of headphones, entertainment service didn't work

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santiago?

    Departing from Greenville to Santiago will take you 19h 35m. Greenville and Santiago are separated by a distance of 4773 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Greenville to Santiago round-trip?

    Currently priced at $753, Delta will fly you from Greenville to Santiago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $758.

  • Can I find deals for flights from Greenville to Santiago that include hotel bookings?

    Yes. In addition to deals on Greenville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santiago.

  • Can I find deals for business class flights from Greenville to Santiago?

    Yes. Cheapflights offers flight deals from Greenville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Greenville to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Savannah to Santiago flights

Top 2 airlines flying from Greenville to Santiago

Discover the top 2 airlines that operate flights from Greenville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$753Average$948FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$758Average$1,185FlexibilityNo cancel feeOn-time81%

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