HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$899+ Cheap flights from Greenville (GSP) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SCL
Aug 29 — Sep 51
Sat 8/29
Sat 9/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Santiago

Cheapest flights from Greenville to Santiago
Explore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:03 am
GSP
-
SCL
1 stop19h 32m
Multiple Airlines
Thu 9/241:43 am
SCL
-
GSP
2 stops17h 40m
Multiple Airlines
Deal found 7/29$899
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:40 pm
GSP
-
SCL
1 stop12h 25m
American Airlines
Wed 9/28:50 pm
SCL
-
GSP
1 stop26h 08m
American Airlines
Deal found 7/27$953
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:00 pm
GSP
-
SCL
2 stops18h 55m
LATAM Airlines
Wed 9/211:00 pm
SCL
-
GSP
2 stops19h 45m
LATAM Airlines
Deal found 7/27$957
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:40 pm
GSP
-
SCL
1 stop12h 25m
American Airlines
Fri 9/259:30 pm
SCL
-
GSP
1 stop26h 00m
American Airlines
Deal found 7/29$962
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:35 pm
GSP
-
SCL
3 stops21h 14m
LATAM Airlines
Sun 9/138:55 pm
SCL
-
GSP
2 stops15h 13m
LATAM Airlines
Deal found 7/28$965
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:26 am
GSP
-
SCL
2 stops20h 24m
United Airlines
Wed 11/410:45 pm
SCL
-
GSP
2 stops20h 11m
United Airlines
Deal found 7/28$970
This LATAM Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:25 pm
GSP
-
SCL
1 stop16h 15m
LATAM Airlines
Wed 11/411:10 pm
SCL
-
GSP
1 stop21h 39m
LATAM Airlines
Deal found 7/25$995
This Orbitz deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:20 pm
GSP
-
SCL
2 stops26h 25m
LATAM Airlines
Sat 9/59:30 pm
SCL
-
GSP
2 stops45h 15m
LATAM Airlines
Deal found 7/25$1,001
This oojo deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:20 pm
GSP
-
SCL
3 stops27h 55m
LATAM Airlines
Fri 9/258:50 am
SCL
-
GSP
2 stops15h 05m
LATAM Airlines
Deal found 7/29$1,014

Find flight deals from Greenville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.

Most accurate provider

Ovago
3 stars

Most trusted provider

Ovago
3 stars

Round-trip from

$899
(Kiwi.com)
Provider with most accurate pricing for Greenville-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Santiago Arturo Merino Benitez flights.
Search Deals
From Greenville to Santiago Arturo Merino Benitez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Greenville to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Fri 8/28

10:03 am-5:35 am

1 stop19h 32m

Santiago Arturo Merino Benitez

Thu 9/24

1:43 am-6:23 pm

2 stops17h 40m

$899

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 8/26

5:19 pm-7:05 am

2 stops13h 46m

Santiago Arturo Merino Benitez

Wed 9/2

8:50 pm-10:58 pm

1 stop26h 08m

$957

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Wed 8/26

12:00 pm-6:55 am

2 stops18h 55m

Santiago Arturo Merino Benitez

Wed 9/2

11:00 pm-6:45 pm

2 stops19h 45m

$957

GreenvilleSantiago

GSP - SCL

GSPSCL

Greenville

Sat 10/31

10:26 am-7:50 am

2 stops20h 24m

Santiago Arturo Merino Benitez

Wed 11/4

10:45 pm-4:56 pm

2 stops20h 11m

$970

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Sorted by cheapest first

Compare providers for flights from Greenville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santiago in July.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Greenville-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Greenville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santiago?

    Departing from Greenville to Santiago will take you 13h 46m. Greenville and Santiago are separated by a distance of 4773 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Greenville to Santiago that include hotel bookings?

    Yes. In addition to deals on Greenville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santiago.

  • Can I find deals for business class flights from Greenville to Santiago?

    Yes. Cheapflights offers flight deals from Greenville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Santiago flights
Savannah to Santiago flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.