$664+ Cheap flights from Greenville (GSP) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SCL
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Santiago
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Best
Last-minute
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Cheapest flights from Greenville to SantiagoExplore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:12 pm -
1 stop13h 38m
Thu 12/1710:45 pm -
1 stop19h 49m
Deal found 10/25![United Airlines logo]()
$1,156
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Thu 12/179:50 pm -
1 stop15h 23m
Deal found 10/25![Delta logo]()
$1,172
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:49 am -
1 stop24h 01m
Thu 12/1710:45 pm -
1 stop19h 49m
Deal found 10/25![United Airlines logo]()
$1,186
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:20 am -
2 stops24h 30m
Fri 12/1810:45 pm -
2 stops24h 06m
Deal found 10/25![United Airlines logo]()
$1,190
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:12 pm -
1 stop17h 28m
Sat 12/199:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,196
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:12 pm -
2 stops16h 48m
Sat 12/1911:10 pm -
2 stops14h 49m
Deal found 10/25![LATAM Airlines logo]()
$1,200
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Fri 12/189:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,202
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:16 pm -
1 stop11h 09m
Fri 12/1811:20 pm -
1 stop16h 03m
Deal found 10/25![American Airlines logo]()
$1,206
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Sat 12/1911:10 pm -
2 stops20h 46m
Deal found 10/25![Delta logo]()
$1,207
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:00 am -
2 stops24h 50m
Fri 12/1810:45 pm -
2 stops24h 06m
Deal found 10/25![United Airlines logo]()
$1,220
Best flights from Greenville to SantiagoDiscover carefully curated flight deals from Greenville to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Greenville to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/12:23 pm -
1 stop15h 22m
Wed 3/319:35 pm -
2 stops18h 56m
Deal found 10/28![American Airlines logo]()
$1,160
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/13:42 pm -
1 stop13h 58m
Wed 3/318:40 pm -
1 stop19h 09m
Deal found 10/29![Delta logo]()
$1,166
This LATAM Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/243:42 pm -
1 stop12h 58m
Sun 3/76:05 pm -
2 stops26h 44m
Deal found 10/28![LATAM Airlines logo]()
$1,166
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:10 pm -
1 stop12h 30m
Fri 12/189:50 pm -
1 stop16h 14m
Deal found 10/25![Delta logo]()
$1,196
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:12 pm -
1 stop17h 28m
Sat 12/199:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,196
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Fri 12/189:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,202
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:00 pm -
1 stop15h 40m
Sat 12/199:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,226
Last-minute flights from Greenville to SantiagoDiscover last-minute flight deals from Greenville to Santiago. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Santiago. Data last updated October 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:12 pm -
1 stop13h 38m
Thu 12/1710:45 pm -
1 stop19h 49m
Deal found 10/25![United Airlines logo]()
$1,156
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:20 am -
2 stops24h 30m
Fri 12/1810:45 pm -
2 stops24h 06m
Deal found 10/25![United Airlines logo]()
$1,190
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:12 pm -
1 stop17h 28m
Sat 12/199:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,196
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:12 pm -
2 stops16h 48m
Sat 12/1911:10 pm -
2 stops14h 49m
Deal found 10/25![LATAM Airlines logo]()
$1,200
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:49 am -
1 stop24h 01m
Thu 12/1710:45 pm -
1 stop19h 49m
Deal found 10/25![United Airlines logo]()
$1,186
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:16 pm -
1 stop11h 09m
Fri 12/1811:20 pm -
1 stop16h 03m
Deal found 10/25![American Airlines logo]()
$1,206
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:00 am -
2 stops24h 50m
Fri 12/1810:45 pm -
2 stops24h 06m
Deal found 10/25![United Airlines logo]()
$1,220
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Thu 12/177:40 am -
2 stops16h 42m
Deal found 10/25![Delta logo]()
$1,172
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Fri 12/189:50 pm -
1 stop13h 34m
Deal found 10/25![Delta logo]()
$1,202
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:19 pm -
1 stop34h 21m
Sat 12/1911:10 pm -
2 stops20h 46m
Deal found 10/25![Delta logo]()
$1,207
One-way flights from Greenville to SantiagoSearch for one-way flight options from Greenville to Santiago. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Greenville to Santiago. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:28 am -
3 stops30h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Multiple Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/155:00 pm -
1 stop13h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$745
This LATAM Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:18 pm -
3 stops21h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![LATAM Airlines logo]()
$903
Find flight deals from Greenville to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $1,156 (United Airlines) |
One-way from | $664 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Greenville to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Tue 12/15
11:28 am-8:11 pm
3 stops30h 43m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$664
Quickest round-trip
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Tue 12/15
5:00 pm-8:50 am
1 stop13h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$745
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Mon 3/1
2:23 pm-7:45 am
1 stop15h 22m
Santiago Arturo Merino Benitez
Wed 3/31
9:35 pm-3:31 pm
2 stops18h 56m
$1,160
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Mon 3/1
3:42 pm-7:40 am
1 stop13h 58m
Santiago Arturo Merino Benitez
Wed 3/31
8:40 pm-2:49 pm
1 stop19h 09m
$1,166
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Wed 2/24
3:42 pm-6:40 am
1 stop12h 58m
Santiago Arturo Merino Benitez
Sun 3/7
6:05 pm-6:49 pm
2 stops26h 44m
$1,166
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Wed 11/25
5:10 pm-7:40 am
1 stop12h 30m
Santiago Arturo Merino Benitez
Fri 12/18
9:50 pm-12:04 pm
1 stop16h 14m
$1,196
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Wed 11/25
12:12 pm-7:40 am
1 stop17h 28m
Santiago Arturo Merino Benitez
Sat 12/19
9:50 pm-9:24 am
1 stop13h 34m
$1,196
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Sun 11/29
7:19 pm-7:40 am
1 stop34h 21m
Santiago Arturo Merino Benitez
Fri 12/18
9:50 pm-9:24 am
1 stop13h 34m
$1,202
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Fri 11/27
2:00 pm-7:40 am
1 stop15h 40m
Santiago Arturo Merino Benitez
Sat 12/19
9:50 pm-9:24 am
1 stop13h 34m
$1,226
Sorted by cheapest first
Compare providers for flights from Greenville to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santiago in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Greenville-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Greenville-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Greenville with our price prediction graph.
GSP-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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