$1,055+ Cheap flights from Greenville (GSP) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SCL
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Santiago
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Best
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Cheapest flights from Greenville to SantiagoExplore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Greenville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:12 pm -
1 stop13h 38m
Mon 11/210:45 pm -
1 stop18h 29m
Deal found 9/13![United Airlines logo]()
$1,055
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:14 pm -
2 stops13h 46m
Mon 9/289:30 pm -
1 stop26h 00m
Deal found 9/14![American Airlines logo]()
$1,070
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:42 am -
2 stops44h 08m
Mon 11/1610:45 pm -
2 stops20h 11m
Deal found 9/14![United Airlines logo]()
$1,079
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:25 pm -
1 stop12h 50m
Sun 9/278:55 pm -
2 stops16h 55m
Deal found 9/14![Delta logo]()
$1,085
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:26 am -
2 stops20h 24m
Mon 11/1610:45 pm -
2 stops20h 11m
Deal found 9/14![United Airlines logo]()
$1,090
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:37 pm -
2 stops37h 13m
Fri 11/1310:45 pm -
2 stops20h 11m
Deal found 9/14![United Airlines logo]()
$1,109
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:14 pm -
1 stop12h 01m
Sun 10/258:35 pm -
2 stops41h 25m
Deal found 9/15![LATAM Airlines logo]()
$1,111
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:00 pm -
1 stop15h 40m
Sun 11/1511:10 pm -
1 stop12h 37m
Deal found 9/14![Delta logo]()
$1,115
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:27 am -
2 stops17h 08m
Sat 12/269:50 pm -
1 stop13h 34m
Deal found 9/14![Delta logo]()
$1,120
This Travelocity deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm -
2 stops30h 45m
Mon 9/289:30 am -
3 stops26h 38m
Deal found 9/14![LATAM Airlines logo]()
$1,121
Best flights from Greenville to SantiagoDiscover carefully curated flight deals from Greenville to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Greenville to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:12 pm -
1 stop13h 38m
Mon 11/210:45 pm -
1 stop18h 29m
Deal found 9/13![United Airlines logo]()
$1,055
This LATAM Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/247:45 am -
3 stops25h 56m
Sun 3/74:35 pm -
2 stops28h 14m
Deal found 9/15![LATAM Airlines logo]()
$1,085
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/245:15 pm -
1 stop13h 35m
Sun 3/710:45 pm -
1 stop18h 33m
Deal found 9/16![United Airlines logo]()
$1,085
Last-minute flights from Greenville to SantiagoDiscover last-minute flight deals from Greenville to Santiago. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Santiago. Data last updated September 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:14 pm -
2 stops13h 46m
Mon 9/289:30 pm -
1 stop26h 00m
Deal found 9/14![American Airlines logo]()
$1,070
This Travelocity deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm -
2 stops30h 45m
Mon 9/289:30 am -
3 stops26h 38m
Deal found 9/14![LATAM Airlines logo]()
$1,121
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:25 pm -
1 stop12h 50m
Mon 9/288:40 pm -
1 stop15h 28m
Deal found 9/14![Delta logo]()
$1,085
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:14 pm -
1 stop12h 01m
Sun 10/258:35 pm -
2 stops41h 25m
Deal found 9/15![LATAM Airlines logo]()
$1,111
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:12 pm -
1 stop13h 38m
Mon 11/210:45 pm -
1 stop18h 29m
Deal found 9/13![United Airlines logo]()
$1,055
This LATAM Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:05 am -
2 stops22h 25m
Mon 11/168:25 pm -
2 stops16h 42m
Deal found 9/14![LATAM Airlines logo]()
$1,115
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:12 pm -
1 stop13h 38m
Fri 11/1310:45 pm -
2 stops20h 11m
Deal found 9/14![United Airlines logo]()
$1,120
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:12 pm -
1 stop13h 38m
Sun 11/1510:45 pm -
2 stops37h 06m
Deal found 9/14![United Airlines logo]()
$1,140
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 pm -
2 stops21h 00m
Sat 11/1411:10 pm -
1 stop13h 57m
Deal found 9/14![Delta logo]()
$1,145
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:26 am -
2 stops20h 24m
Thu 11/1210:45 pm -
2 stops24h 13m
Deal found 9/14![United Airlines logo]()
$1,090
One-way flights from Greenville to SantiagoSearch for one-way flight options from Greenville to Santiago. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Greenville to Santiago. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:00 am -
3 stops52h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$1,986
This BusinessClass deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:42 am -
2 stops36h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Copa Airlines logo]()
$2,285
This BusinessClass deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:39 pm -
2 stops22h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![LATAM Airlines logo]()
$2,770
This BusinessClass deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:14 pm -
2 stops18h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![LATAM Airlines logo]()
$2,815
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:57 pm -
3 stops28h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$2,832
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:00 am -
2 stops21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$3,068
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:42 am -
2 stops20h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$3,074
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:08 pm -
1 stop11h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$3,318
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:08 pm -
1 stop11h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$3,468
Find flight deals from Greenville to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $1,055 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Greenville to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Thu 10/29
5:12 pm-7:50 am
1 stop13h 38m
Santiago Arturo Merino Benitez
Mon 11/2
10:45 pm-3:14 pm
1 stop18h 29m
$1,055
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Wed 2/24
7:45 am-11:41 am
3 stops25h 56m
Santiago Arturo Merino Benitez
Sun 3/7
4:35 pm-6:49 pm
2 stops28h 14m
$1,085
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Wed 2/24
5:15 pm-8:50 am
1 stop13h 35m
Santiago Arturo Merino Benitez
Sun 3/7
10:45 pm-3:18 pm
1 stop18h 33m
$1,085
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Sun 10/25
10:08 am-5:40 pm
3 stops54h 32m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$2,357
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Mon 10/26
3:39 pm-3:00 pm
2 stops22h 21m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$2,770
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Sun 10/25
7:14 pm-3:00 pm
2 stops18h 46m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$2,815
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Mon 10/26
6:57 pm-12:22 am
3 stops28h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$2,832
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Sun 10/25
7:00 am-5:20 am
2 stops21h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$3,068
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Sun 10/25
10:42 am-7:50 am
2 stops20h 08m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$3,074
Quickest round-trip
GreenvilleSantiago
GSP Greenville - SCL Santiago Arturo Merino Benitez
GSPSCL
Greenville
Mon 10/26
8:08 pm-8:35 am
1 stop11h 27m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$4,018
Sorted by cheapest first
Compare providers for flights from Greenville to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Greenville-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Greenville-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Greenville with our price prediction graph.
GSP-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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