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South America

$185+ Cheap flights from Greenville (GSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Find flight deals from Greenville to South America

Cheapest flights from Greenville to South America
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/234:43 pmGSP - MDE
2 stops32h 45mMultiple Airlines
jue. 1/223:11 pmMDE - GSP
1 stop17h 47mMultiple Airlines
Deal found 11/5$437
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:40 pmGSP - MDE
1 stop8h 48mMultiple Airlines
jue. 1/151:00 pmMDE - GSP
1 stop19h 58mMultiple Airlines
Deal found 11/4$449
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/229:34 pmGSP - MDE
2 stops35h 37mMultiple Airlines
dom. 11/301:51 amMDE - GSP
1 stop12h 52mMultiple Airlines
Deal found 11/3$492
This Orbitz deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/277:59 pmGSP - BOG
2 stops48h 21mLATAM Airlines
lun. 1/263:55 pmBOG - GSP
1 stop8h 00mLATAM Airlines
Deal found 11/5$547
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:33 amGSP - MDE
1 stop23h 22mMultiple Airlines
sáb. 1/109:40 pmMDE - GSP
2 stops35h 18mMultiple Airlines
Deal found 11/4$551
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/1312:19 pmGSP - MDE
2 stops17h 23mUnited Airlines
mar. 12/3010:45 amMDE - GSP
1 stop11h 12mUnited Airlines
Deal found 11/4$553
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/910:26 amGSP - MDE
1 stop10h 44mAmerican Airlines
mar. 12/237:00 amMDE - GSP
1 stop12h 37mAmerican Airlines
Deal found 11/4$555
This Ovago deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/267:59 pmGSP - BOG
1 stop23h 31mLATAM Airlines
lun. 1/263:55 pmBOG - GSP
1 stop17h 26mLATAM Airlines
Deal found 11/5$626
This Aviatur deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/77:52 amGSP - BOG
1 stop11h 38mLATAM Airlines
vie. 11/149:00 amBOG - GSP
1 stop14h 45mLATAM Airlines
Deal found 11/6$631
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/105:00 amGSP - BOG
1 stop17h 10mAmerican Airlines
mié. 11/1211:55 pmBOG - GSP
1 stop11h 38mAmerican Airlines
Deal found 11/6$632
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/77:52 amGSP - BOG
1 stop6h 33mDelta
lun. 11/106:15 amBOG - GSP
2 stops16h 19mDelta
Deal found 11/5$633
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/274:02 pmGSP - BOG
1 stop20h 50mMultiple Airlines
dom. 1/251:05 amBOG - GSP
2 stops14h 54mMultiple Airlines
Deal found 11/5$634

Cheap flight deals from Greenville to South America

Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated noviembre 6, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$437
(Kiwi.com)

One-way from

$185
(Kiwi.com)
Provider with most accurate pricing for Greenville-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Sao Paulo (SAO) flights.
Search Deals
From Greenville to South America
Search Deals
One-way flight from Greenville to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Greenville

Fly to

South America

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

mar. 12/23

4:43 pm-1:28 am

2 stops32h 45m

Medellín Jose Maria Cordova Intl

jue. 1/22

3:11 pm-8:58 am

1 stop17h 47m

$437

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

vie. 1/23

4:39 pm-2:16 pm

2 stops45h 37m

Medellín Jose Maria Cordova Intl

lun. 1/26

6:35 am-3:59 pm

1 stop9h 24m

$495

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

sáb. 11/22

9:34 pm-6:35 am

3 stops33h 01m

Medellín Jose Maria Cordova Intl

dom. 11/30

1:51 am-2:43 pm

1 stop12h 52m

$504

GreenvillePereira

GSP - PEI

GSPPEI

Greenville

mar. 1/20

6:20 am-8:23 pm

2 stops38h 03m

Pereira Matecana

mar. 2/10

2:55 pm-11:48 pm

2 stops32h 53m

$511

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

sáb. 5/2

6:45 am-7:25 pm

1 stop13h 40m

Bogotá El Dorado

mié. 5/6

2:55 pm-9:28 am

1 stop17h 33m

$520

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

mié. 3/11

12:00 pm-8:20 pm

2 stops9h 20m

Bogotá El Dorado

vie. 3/13

3:55 pm-9:27 am

1 stop16h 32m

$543

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

vie. 1/23

5:34 pm-10:05 pm

2 stops28h 31m

Medellín Jose Maria Cordova Intl

dom. 2/8

10:45 am-2:19 pm

2 stops27h 34m

$547

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

vie. 1/23

6:55 pm-2:06 pm

1 stop19h 11m

Medellín Jose Maria Cordova Intl

dom. 2/8

7:00 am-11:57 pm

1 stop16h 57m

$556

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

sáb. 11/29

4:05 pm-12:56 am

1 stop8h 51m

Medellín Jose Maria Cordova Intl

vie. 12/12

2:05 am-1:26 pm

2 stops35h 21m

$564

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

mar. 3/10

6:50 am-11:00 pm

2 stops17h 10m

Cartagena Rafael Nunez

vie. 3/13

6:25 am-9:52 pm

2 stops14h 27m

$569

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 59 results
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SA?

Find hourly flight availability from Greenville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

One of the essential ways to save on airfare from Greenville to South America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 23% on airfare.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated noviembre 6, 2025.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,874 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,041 reviews
Delta
7.9
Good
8,004 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • How long is the flight from Greenville to South America?

    Delta, LATAM Airlines, and United Airlines can get you from Greenville to South America in just under 9h 20m. Your travel time can differ by up to 19h 11m. The distance from Greenville to South America is about 2148 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Greenville to South America one-way?

    To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $277. United Airlines flights start at $309 while deals on LATAM Airlines start at $341 one-way.

  • What are the most popular routes from Greenville to South America?

    The most popular route from Greenville to South America is Greenville - Medellín Jose Maria Cordova Intl. You may also consider Greenville - Lima J Chavez Intl or Greenville - Bogotá El Dorado.

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Greenville to South America

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Top 3 airlines flying from Greenville to South America

Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$502Average$876FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$502Average$899FlexibilityNo cancel feeOn-time71%
DeltaCheapest$532Average$923FlexibilityNo cancel feeOn-timeN/A

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