$176+ Cheap flights from San Francisco (SFO) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from San Francisco to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to South America
Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated June 12, 2025.
Round-trip from | $400 (Gotogate) |
|---|---|
One-way from | $176 (FlightHub) |
Popular in | December |
Cheapest in | October |
Average price | $940 |
Find flight deals from San Francisco to South America
Cheapest flights from San Francisco to South AmericaExplore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This Gotogate deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Gotogate deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Vliegwinkel deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This JetBlue deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Copa Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Wed 9/10
2:20 pm-2:05 am
1 stop9h 45m
Medellín Jose Maria Cordova Intl
Thu 9/18
3:15 am-12:35 pm
1 stop11h 20m
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Sat 8/16
1:28 am-2:15 pm
1 stop10h 47m
Medellín Jose Maria Cordova Intl
Thu 8/28
6:40 am-11:40 pm
1 stop19h 00m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Wed 9/10
2:20 pm-5:27 am
2 stops13h 07m
Bogotá El Dorado
Sat 9/20
2:20 pm-11:55 pm
1 stop11h 35m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Sun 8/17
10:59 pm-1:40 pm
1 stop12h 41m
Bogotá El Dorado
Wed 8/27
1:35 am-6:52 pm
2 stops19h 17m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Mon 8/4
11:59 pm-7:20 pm
1 stop17h 21m
Bogotá El Dorado
Wed 9/10
12:14 am-4:34 pm
1 stop18h 20m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Sun 8/31
12:43 am-7:20 pm
1 stop16h 37m
Bogotá El Dorado
Fri 9/19
12:14 am-12:19 pm
1 stop14h 05m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Wed 8/6
1:41 pm-10:55 am
2 stops19h 14m
Bogotá El Dorado
Wed 9/10
1:35 am-9:02 pm
2 stops21h 27m
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Sun 9/7
5:03 pm-12:51 pm
2 stops17h 48m
Medellín Jose Maria Cordova Intl
Fri 9/26
1:46 pm-11:08 pm
1 stop11h 22m
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Mon 7/28
9:14 pm-1:55 pm
1 stop14h 41m
Medellín Jose Maria Cordova Intl
Tue 8/26
1:30 pm-11:36 pm
1 stop12h 06m
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Mon 6/23
1:37 am-1:29 pm
1 stop9h 52m
Bogotá El Dorado
Tue 7/1
2:24 pm-11:40 pm
1 stop11h 16m
Best time to book a flight from San Francisco to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South America
What is the cheapest month to book a flight from San Francisco to South America?
Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $359). Flying from San Francisco to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to SA?
Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
When flying from San Francisco to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in South America by month
Plan your trip to South America by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.
Temperature in South America by month
Plan your trip to South America by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated June 12, 2025.
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Food
Boarding
Entertainment
Overall
Comfort
Crew
Reviews
Mike,Feb 2025
NVT - LIS
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for San Francisco to South America
See prices for flight routes from nearby airports that may be better suited for you.
Top 10 airlines flying from San Francisco to South America
Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$242 | Average$466 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$368 | Average$854 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$387 | Average$876 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$389 | Average$626 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$389 | Average$918 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$389 | Average$860 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$402 | Average$924 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$407 | Average$781 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$539 | Average$844 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$678 | Average$963 | FlexibilityNo cancel fee | On-timeN/A |