$120+ Cheap flights from San Francisco (SFO) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to South America
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Cheapest flights from San Francisco to South AmericaExplore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
SFO
- BOG
1 stop12h 20m
United Airlines
Mon 4/2712:14 am
BOG
- SFO
1 stop12h 26m
United Airlines
Deal found 3/9![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
SFO
- BOG
1 stop20h 31m
American Airlines
Fri 4/2412:25 am
BOG
- SFO
2 stops17h 00m
American Airlines
Deal found 3/9![American Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:59 pm
SFO
- BOG
1 stop26h 55m
United Airlines
Tue 4/218:30 am
BOG
- SFO
1 stop12h 28m
United Airlines
Deal found 3/9![United Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:15 am
SFO
- BOG
1 stop10h 05m
United Airlines
Thu 5/78:30 am
BOG
- SFO
1 stop17h 29m
United Airlines
Deal found 3/8![United Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3012:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Wed 4/159:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/9![United Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:00 am
SFO
- BOG
2 stops11h 30m
American Airlines
Wed 4/2212:25 am
BOG
- SFO
1 stop24h 44m
American Airlines
Deal found 3/8![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Fri 4/179:45 am
MDE
- SFO
1 stop14h 45m
United Airlines
Deal found 3/9![United Airlines logo]()
$357
This Avianca deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:55 pm
SFO
- MDE
1 stop11h 15m
Avianca
Thu 4/3010:40 am
MDE
- SFO
2 stops15h 15m
Avianca
Deal found 3/10![Avianca logo]()
$358
This BusinessClass deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:28 pm
SFO
- MDE
2 stops19h 47m
GOL
Wed 5/276:00 am
MDE
- SFO
2 stops18h 49m
GOL
Deal found 3/10![GOL logo]()
$360
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Wed 4/229:45 am
MDE
- SFO
1 stop11h 13m
United Airlines
Deal found 3/10![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:15 am
SFO
- BOG
1 stop10h 05m
United Airlines
Sun 5/1712:14 am
BOG
- SFO
1 stop33h 01m
United Airlines
Deal found 3/9![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:45 am
SFO
- BOG
1 stop16h 35m
United Airlines
Tue 4/218:30 am
BOG
- SFO
1 stop17h 29m
United Airlines
Deal found 3/10![United Airlines logo]()
$363
Best flights from San Francisco to South AmericaDiscover carefully curated flight deals from San Francisco to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from San Francisco to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:59 pm
SFO
- MDE
1 stop19h 11m
United Airlines
Fri 4/179:45 am
MDE
- SFO
1 stop28h 33m
United Airlines
Deal found 3/9![United Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:35 pm
SFO
- BOG
2 stops18h 15m
Delta
Tue 4/282:55 pm
BOG
- SFO
2 stops21h 33m
Delta
Deal found 3/7![Delta logo]()
$400
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/171:12 am
SFO
- LIM
1 stop22h 08m
Copa Airlines
Wed 8/197:00 am
LIM
- SFO
1 stop12h 59m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:00 am
SFO
- LIM
2 stops17h 10m
American Airlines
Sun 4/2611:45 pm
LIM
- SFO
1 stop25h 16m
American Airlines
Deal found 3/7![American Airlines logo]()
$561
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/102:15 pm
SFO
- SCL
2 stops21h 00m
Avianca
Wed 4/223:20 pm
SCL
- SFO
2 stops35h 35m
Avianca
Deal found 3/7![Avianca logo]()
$681
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:00 am
SFO
- BOG
1 stop12h 20m
United Airlines
Thu 5/78:30 am
BOG
- SFO
1 stop17h 29m
United Airlines
Deal found 3/10![United Airlines logo]()
$363
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:04 am
SFO
- SCL
1 stop20h 16m
Multiple Airlines
Sun 8/911:00 pm
SCL
- SFO
2 stops23h 24m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1912:45 am
SFO
- BOG
1 stop16h 35m
United Airlines
Tue 4/288:30 am
BOG
- SFO
1 stop16h 00m
United Airlines
Deal found 3/9![United Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:50 pm
SFO
- BOG
2 stops24h 20m
Delta
Mon 4/2710:35 am
BOG
- SFO
2 stops23h 10m
Delta
Deal found 3/8![Delta logo]()
$400
This FlightHub deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:25 am
SFO
- SCL
1 stop17h 10m
LATAM Airlines
Wed 4/2211:25 pm
SCL
- SFO
1 stop15h 34m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$833
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:35 pm
SFO
- BOG
1 stop13h 05m
Delta
Mon 4/2710:35 am
BOG
- SFO
2 stops23h 10m
Delta
Deal found 3/8![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Fri 5/159:45 am
MDE
- SFO
1 stop11h 20m
United Airlines
Deal found 3/7![United Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/511:57 pm
SFO
- BOG
1 stop17h 18m
Delta
Thu 5/1411:00 am
BOG
- SFO
2 stops23h 21m
Delta
Deal found 3/10![Delta logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:12 am
SFO
- LIM
1 stop22h 08m
Copa Airlines
Fri 6/54:00 am
LIM
- SFO
1 stop21h 40m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Wed 4/159:45 am
MDE
- SFO
1 stop14h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$402
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:20 pm
SFO
- BOG
1 stop21h 20m
Delta
Wed 4/292:55 pm
BOG
- SFO
2 stops23h 26m
Delta
Deal found 3/9![Delta logo]()
$420
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:06 pm
SFO
- LIM
1 stop21h 09m
Copa Airlines
Wed 6/311:00 am
LIM
- SFO
1 stop14h 40m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$531
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:55 pm
SFO
- BOG
1 stop22h 25m
United Airlines
Sat 5/98:30 am
BOG
- SFO
1 stop12h 35m
United Airlines
Deal found 3/7![United Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Fri 4/179:45 am
MDE
- SFO
1 stop14h 45m
United Airlines
Deal found 3/9![United Airlines logo]()
$404
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:23 am
SFO
- LIM
1 stop19h 22m
Copa Airlines
Fri 5/12:35 am
LIM
- SFO
1 stop17h 39m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$551
This Priceline deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:15 pm
SFO
- SDU
2 stops45h 00m
Air Canada
Mon 4/131:50 pm
SDU
- SFO
2 stops35h 32m
Air Canada
Deal found 3/8![Air Canada logo]()
$1,425
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:45 am
SFO
- BOG
1 stop16h 35m
United Airlines
Sun 5/38:30 am
BOG
- SFO
1 stop24h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$404
This BusinessClass deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:53 am
SFO
- SDU
2 stops42h 47m
Azul
Tue 3/171:50 pm
SDU
- SFO
2 stops27h 40m
Azul
Deal found 3/11![Azul logo]()
$1,457
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:12 am
SFO
- LIM
1 stop20h 28m
Copa Airlines
Thu 5/141:20 pm
LIM
- SFO
1 stop12h 20m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:05 am
SFO
- SCL
2 stops18h 45m
American Airlines
Sun 8/98:30 pm
SCL
- SFO
2 stops19h 36m
American Airlines
Deal found 3/7![American Airlines logo]()
$790
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
SFO
- SCL
1 stop22h 15m
Multiple Airlines
Wed 4/223:20 pm
SCL
- SFO
2 stops35h 35m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$793
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:59 pm
SFO
- LIM
2 stops18h 21m
Delta
Thu 5/288:55 am
LIM
- SFO
2 stops17h 51m
Delta
Deal found 3/7![Delta logo]()
$545
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Thu 4/29:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/7![United Airlines logo]()
$413
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:37 pm
SFO
- LIM
1 stop17h 03m
Copa Airlines
Sun 4/194:00 am
LIM
- SFO
1 stop21h 40m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Wed 4/159:45 am
MDE
- SFO
1 stop14h 45m
United Airlines
Deal found 3/8![United Airlines logo]()
$418
Last-minute flights from San Francisco to South AmericaDiscover last-minute flight deals from San Francisco to South America. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to South America. Data last updated March 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3012:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Wed 4/159:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/9![United Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Fri 4/179:45 am
MDE
- SFO
1 stop14h 45m
United Airlines
Deal found 3/9![United Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Wed 4/159:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/9![United Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:55 pm
SFO
- MDE
1 stop24h 15m
United Airlines
Thu 4/169:45 am
MDE
- SFO
1 stop31h 08m
United Airlines
Deal found 3/9![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:00 am
SFO
- MDE
1 stop14h 10m
United Airlines
Fri 4/179:45 am
MDE
- SFO
1 stop23h 31m
United Airlines
Deal found 3/9![United Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1111:59 pm
SFO
- BOG
1 stop26h 55m
United Airlines
Tue 4/2112:14 am
BOG
- SFO
1 stop12h 26m
United Airlines
Deal found 3/9![United Airlines logo]()
$352
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:55 pm
SFO
- MDE
1 stop11h 15m
Avianca
Tue 4/212:10 pm
MDE
- SFO
1 stop11h 45m
Avianca
Deal found 3/9![Avianca logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:00 am
SFO
- BOG
2 stops11h 30m
American Airlines
Wed 4/2212:25 am
BOG
- SFO
1 stop24h 44m
American Airlines
Deal found 3/8![American Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:45 am
SFO
- BOG
1 stop16h 35m
United Airlines
Tue 4/218:30 am
BOG
- SFO
1 stop17h 29m
United Airlines
Deal found 3/10![United Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
SFO
- BOG
1 stop12h 20m
United Airlines
Mon 4/2712:14 am
BOG
- SFO
1 stop12h 26m
United Airlines
Deal found 3/9![United Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
SFO
- BOG
1 stop20h 31m
American Airlines
Fri 4/2412:25 am
BOG
- SFO
2 stops17h 00m
American Airlines
Deal found 3/9![American Airlines logo]()
$348
This Avianca deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:55 pm
SFO
- MDE
1 stop11h 15m
Avianca
Thu 4/3010:40 am
MDE
- SFO
2 stops15h 15m
Avianca
Deal found 3/10![Avianca logo]()
$358
One-way flights from San Francisco to South AmericaSearch for one-way flight options from San Francisco to South America. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from San Francisco to South America. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This 123 Milhas deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure 123 Milhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:30 am
SFO
- GRU
1 stop16h 00m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$120
This 123 Milhas deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure 123 Milhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:00 am
SFO
- GRU
1 stop18h 30m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$132
This 123 Milhas deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure 123 Milhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:25 pm
SFO
- GRU
2 stops21h 35m
LATAM Airlines
Deal found 3/10![LATAM Airlines logo]()
$136
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:59 pm
SFO
- MDE
1 stop19h 11m
United Airlines
Deal found 3/8![United Airlines logo]()
$138
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Deal found 3/7![United Airlines logo]()
$141
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:30 am
SFO
- MDE
2 stops17h 45m
American Airlines
Deal found 3/8![American Airlines logo]()
$142
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:00 am
SFO
- BOG
1 stop12h 20m
United Airlines
Deal found 3/8![United Airlines logo]()
$144
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:30 am
SFO
- MDE
2 stops17h 45m
American Airlines
Deal found 3/8![American Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:59 pm
SFO
- BOG
1 stop20h 31m
American Airlines
Deal found 3/7![American Airlines logo]()
$147
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:00 pm
SFO
- BOG
1 stop21h 20m
American Airlines
Deal found 3/9![American Airlines logo]()
$148
This Avianca deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 am
SFO
- MDE
2 stops13h 40m
Avianca
Deal found 3/7![Avianca logo]()
$150
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:59 am
SFO
- MDE
2 stops17h 16m
American Airlines
Deal found 3/9![American Airlines logo]()
$152
Find flight deals from San Francisco to South America
Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated March 12, 2026.
Round-trip from | $343 (United Airlines) |
|---|---|
One-way from | $120 (123 Milhas) |
Popular in | December |
Cheapest in | August |
Average price | $508 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Sat 4/11
11:59 pm-9:10 pm
1 stop19h 11m
Medellín Jose Maria Cordova Intl
Fri 4/17
9:45 am-12:18 pm
1 stop28h 33m
$362
Quickest round-trip
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Tue 5/5
5:00 am-7:20 pm
1 stop12h 20m
Bogotá El Dorado
Thu 5/7
8:30 am-11:59 pm
1 stop17h 29m
$363
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Sun 4/19
12:45 am-7:20 pm
1 stop16h 35m
Bogotá El Dorado
Tue 4/28
8:30 am-10:30 pm
1 stop16h 00m
$363
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Mon 4/20
9:35 pm-5:50 pm
2 stops18h 15m
Bogotá El Dorado
Tue 4/28
2:55 pm-10:28 am
2 stops21h 33m
$400
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Sat 4/18
5:50 pm-8:10 pm
2 stops24h 20m
Bogotá El Dorado
Mon 4/27
10:35 am-7:45 am
2 stops23h 10m
$400
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Fri 4/17
10:35 pm-1:40 pm
1 stop13h 05m
Bogotá El Dorado
Mon 4/27
10:35 am-7:45 am
2 stops23h 10m
$400
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Fri 5/1
6:55 pm-9:10 pm
1 stop24h 15m
Medellín Jose Maria Cordova Intl
Fri 5/15
9:45 am-7:05 pm
1 stop11h 20m
$402
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Fri 4/10
6:55 pm-9:10 pm
1 stop24h 15m
Medellín Jose Maria Cordova Intl
Wed 4/15
9:45 am-10:30 pm
1 stop14h 45m
$402
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Fri 5/1
6:55 pm-7:20 pm
1 stop22h 25m
Bogotá El Dorado
Sat 5/9
8:30 am-7:05 pm
1 stop12h 35m
$403
San FranciscoMedellín
SFO - MDE
SFOMDE
San Francisco
Wed 4/1
6:55 pm-9:10 pm
1 stop24h 15m
Medellín Jose Maria Cordova Intl
Fri 4/17
9:45 am-10:30 pm
1 stop14h 45m
$404
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
SFO-BOG
SFO-MDE
SFO-GRU
SFO-LIM
SFO-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South America
SFO-0SA
SFO-BOG
SFO-MDE
SFO-GRU
SFO-LIM
What is the cheapest month to book a flight from San Francisco to South America?
Currently, October is the cheapest month in which you can book a flight from San Francisco to South America (average of $213). Flying from San Francisco to South America in January is currently the most expensive (average of $393). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 12, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,LATAM Airlines, andUnited Airlines from San Francisco to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Comfort
7.4
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Francisco to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to South America by cabin class
Find flights from San Francisco to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and South America flights
Browse other San Francisco and South America flight options. Last updated on March 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
San Francisco to South America flights
Consider these flights traveling from San Francisco to South America.
Top 10 airlines flying from San Francisco to South America
Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$214 | Average$795 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$224 | Average$734 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$258 | Average$797 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$269 | Average$746 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$282 | Average$879 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$314 | Average$648 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$453 | Average$1,061 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$459 | Average$895 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$565 | Average$752 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$668 | Average$1,435 | FlexibilityNo cancel fee | On-time74% |