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South America

$138+ Cheap flights from San Francisco (SFO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from San Francisco to South America

Cheapest flights from San Francisco to South America
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1011:15 amSFO - BOG
1 stop14h 55mUnited Airlines
mar. 12/161:30 amBOG - SFO
1 stop13h 39mUnited Airlines
Deal found 12/10$489
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1411:59 pmSFO - MDE
1 stop19h 06mUnited Airlines
jue. 12/181:15 amMDE - SFO
1 stop18h 37mUnited Airlines
Deal found 12/11$513
This LATAM Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/215:15 pmSFO - BOG
2 stops24h 05mLATAM Airlines
lun. 1/510:55 amBOG - SFO
2 stops28h 54mLATAM Airlines
Deal found 12/11$518
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:36 amSFO - MDE
1 stop10h 39mCopa Airlines
lun. 12/1510:46 amMDE - SFO
1 stop15h 31mCopa Airlines
Deal found 12/10$524
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1211:59 pmSFO - LIM
1 stop20h 56mUnited Airlines
mar. 12/161:50 amLIM - SFO
1 stop13h 19mUnited Airlines
Deal found 12/10$545
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:36 amSFO - BOG
1 stop13h 50mCopa Airlines
jue. 12/1812:08 pmBOG - SFO
1 stop14h 09mCopa Airlines
Deal found 12/10$551
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:36 amSFO - LIM
1 stop19h 29mCopa Airlines
jue. 12/1810:30 amLIM - SFO
1 stop15h 47mCopa Airlines
Deal found 12/10$553
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/155:00 amSFO - MDE
1 stop14h 05mUnited Airlines
jue. 12/1810:45 amMDE - SFO
1 stop13h 41mUnited Airlines
Deal found 12/11$553
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/1311:59 pmSFO - MDE
1 stop19h 06mUnited Airlines
dom. 12/211:15 amMDE - SFO
1 stop26h 06mUnited Airlines
Deal found 12/11$563
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/3011:59 pmSFO - LIM
1 stop20h 56mUnited Airlines
jue. 2/51:50 amLIM - SFO
1 stop19h 00mUnited Airlines
Deal found 12/11$574
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/1411:59 pmSFO - CTG
1 stop12h 31mAmerican Airlines
dom. 12/212:30 pmCTG - SFO
1 stop12h 29mAmerican Airlines
Deal found 12/11$581
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/156:00 amSFO - MDE
2 stops14h 39mAmerican Airlines
dom. 12/217:00 amMDE - SFO
1 stop19h 59mAmerican Airlines
Deal found 12/10$586

Find flight deals from San Francisco to South America

Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated diciembre 12, 2025.

Round-trip from

$450
(Copa Airlines)

One-way from

$138
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$903
From San Francisco to South America
Search Deals
One-way flight from San Francisco to South America
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($104 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

San Francisco

Fly to

South America

Route

Depart

Return

Price

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

jue. 1/22

1:19 pm-5:10 am

1 stop12h 51m

Bogotá El Dorado

mar. 2/3

8:15 am-4:50 pm

1 stop11h 35m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

vie. 4/10

2:18 pm-4:54 am

1 stop12h 36m

Bogotá El Dorado

vie. 4/17

12:14 am-10:42 am

1 stop12h 28m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

jue. 1/22

9:05 am-10:35 pm

1 stop10h 30m

Bogotá El Dorado

jue. 2/5

1:30 am-12:20 pm

1 stop13h 50m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

dom. 4/12

7:00 am-7:20 pm

1 stop10h 20m

Bogotá El Dorado

vie. 4/17

12:14 am-10:42 am

1 stop12h 28m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

jue. 4/16

2:18 pm-4:54 am

1 stop12h 36m

Bogotá El Dorado

jue. 4/23

12:14 am-10:42 am

1 stop12h 28m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

mié. 1/28

9:05 am-10:35 pm

1 stop10h 30m

Bogotá El Dorado

lun. 2/2

8:15 am-5:50 pm

1 stop12h 35m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

dom. 4/12

7:00 am-7:20 pm

1 stop10h 20m

Bogotá El Dorado

jue. 4/16

12:14 am-10:42 am

1 stop12h 28m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

mar. 3/10

8:45 am-11:05 pm

1 stop12h 20m

Bogotá El Dorado

lun. 3/30

12:14 am-10:42 am

1 stop12h 28m

$459

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

mié. 2/4

12:42 am-2:04 pm

1 stop10h 22m

Cartagena Rafael Nunez

mar. 2/10

9:42 am-11:20 pm

1 stop16h 38m

$470

San FranciscoCartagena

SFO - CTG

SFOCTG

San Francisco

mar. 2/24

12:42 am-2:04 pm

1 stop10h 22m

Cartagena Rafael Nunez

dom. 3/1

9:42 am-11:16 pm

1 stop16h 34m

$470

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South America

What is the cheapest month to book a flight from San Francisco to South America?

Currently, October is the cheapest month in which you can book a flight from San Francisco to South America (average of $220). Flying from San Francisco to South America in December is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SA?

Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

It’s optimal to fly from San Francisco to South America in the afternoon. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from San Francisco to South America?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated diciembre 12, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, LATAM Airlines, and United Airlines from San Francisco to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,558 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,889 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,095 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
11,049 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,480 reviews
Copa Airlines
7.6
Good
1,558 reviews

Food

6.9

Boarding

7.8

Comfort

7.4

Overall

7.6

Entertainment

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to South America?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to South America. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to South America?

    Airlines like United Airlines, American Airlines, and Copa Airlines fly from San Francisco to South America in about 12h 51m. The time it takes to get you to your destination can typically vary by up to 11h 27m. The distance from San Francisco to South America is about 3786 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Francisco to South America one-way?

    $173 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from $178 and $192, respectively.

  • What are the most popular routes from San Francisco to South America?

    While some choose either San Francisco - Buenos Aires Ministro Pistarini or San Francisco - Bogotá El Dorado, San Francisco - Lima J Chavez Intl is the most popular route from San Francisco to South America.

  • Can I find deals for flights from San Francisco to South America that include hotel bookings?

    Yes. In addition to deals on San Francisco to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South America.

  • Can I find deals for business class flights from San Francisco to South America?

    Yes. Cheapflights offers flight deals from San Francisco to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South America?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to South America (average of $220). Flying from San Francisco to South America in December is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to South America

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Top 10 airlines flying from San Francisco to South America

Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$358Average$837FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$381Average$670FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$392Average$803FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$402Average$771FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$409Average$642FlexibilityNo cancel feeOn-time62%
LATAM AirlinesCheapest$423Average$796FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$463Average$895FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$531Average$752FlexibilityNo cancel feeOn-time67%
AeromexicoCheapest$652Average$1,057FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$747Average$1,663FlexibilityNo cancel feeOn-time74%

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