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Santa Cruz de la Sierra

$394+ Cheap flights from San Francisco (SFO) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — VVI
Jun 16 — Jun 231
Tue 6/16
Tue 6/23
1 adult, Economy
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Cheap flight deals from San Francisco to Santa Cruz de la Sierra

Cheapest flights from San Francisco to Santa Cruz de la Sierra
Explore the most affordable flight options available from San Francisco to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This Copa Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:21 pm
SFO
-
VVI
1 stop28h 14m
Copa Airlines
Tue 9/81:12 am
VVI
-
SFO
1 stop19h 58m
Copa Airlines
Deal found 5/16$774
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:45 am
SFO
-
VVI
2 stops18h 53m
Copa Airlines
Mon 6/111:47 am
VVI
-
SFO
2 stops32h 55m
Copa Airlines
Deal found 5/16$812
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:45 am
SFO
-
VVI
2 stops18h 59m
Multiple Airlines
Mon 9/143:35 am
VVI
-
SFO
2 stops17h 54m
Multiple Airlines
Deal found 5/16$823
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:45 am
SFO
-
VVI
2 stops23h 46m
United Airlines
Mon 5/2511:47 am
VVI
-
SFO
2 stops39h 58m
United Airlines
Deal found 5/13$826
This Copa Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:16 pm
SFO
-
VVI
1 stop28h 19m
Copa Airlines
Sat 8/291:12 am
VVI
-
SFO
1 stop25h 28m
Copa Airlines
Deal found 5/15$867
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:35 pm
SFO
-
VVI
2 stops21h 09m
United Airlines
Thu 9/1711:47 am
VVI
-
SFO
2 stops24h 31m
United Airlines
Deal found 5/12$903
This Justfly.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:55 pm
SFO
-
VVI
2 stops23h 35m
Avianca
Sun 5/313:35 am
VVI
-
SFO
3 stops29h 50m
Avianca
Deal found 5/13$991

Find flight deals from San Francisco to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$774
(Copa Airlines)

One-way from

$394
(KAYAK)

Popular in

December

Cheapest in

March

Average price

$1,022
Provider with most accurate pricing for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From San Francisco to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from San Francisco to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($173 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($65 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Wed 8/12

8:21 pm-3:35 am

1 stop28h 14m

Santa Cruz de la Sierra Viru Viru Intl

Tue 9/8

1:12 am-6:10 pm

1 stop19h 58m

$774

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 7/30

8:16 pm-10:40 pm

1 stop23h 24m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/29

1:12 am-11:40 pm

1 stop25h 28m

$822

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 9/14

12:29 pm-10:44 pm

2 stops31h 15m

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/17

11:47 am-9:18 am

2 stops24h 31m

$903
Cheapest one-way

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sun 6/14

12:15 pm-10:38 pm

2 stops31h 23m

$394

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 6/15

2:20 pm-10:38 pm

2 stops29h 18m

$395
Quickest one-way

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 5/30

11:30 pm-10:38 pm

2 stops20h 08m

$395

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Thu 6/11

9:00 pm-10:38 pm

2 stops46h 38m

$440

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Sat 5/30

8:16 pm-10:38 pm

1 stop23h 22m

$456

San FranciscoSanta Cruz de la Sierra

SFO - VVI

SFOVVI

San Francisco

Mon 6/8

3:33 pm-5:00 pm

3 stops22h 27m

$614

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/16

Sorted by cheapest first

Compare providers for flights from San Francisco to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santa Cruz de la Sierra in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
BusinessClassPrice Accuracy-Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santa Cruz de la Sierra

What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

Currently, March is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $356). Flying from San Francisco to Santa Cruz de la Sierra in December is currently the most expensive (average of $1,667). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from San Francisco to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated May 17, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from San Francisco to Santa Cruz de la Sierra by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,584 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,584 reviews
Copa Airlines
7.5
Good
1,584 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
United Airlines
7.4
Good
9,730 reviews
Copa Airlines
7.5
Good
1,584 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Food

6.8

Overall

7.5

Comfort

7.4

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santa Cruz de la Sierra?

    For as low as $774, Copa Airlines can have you in Santa Cruz de la Sierra from San Francisco in 28h 14m. The distance from San Francisco to Santa Cruz de la Sierra is about 5414 mi.

  • What are the cheapest airlines flying from San Francisco to Santa Cruz de la Sierra round-trip?

    Cheapflights users have booked flights from San Francisco to Santa Cruz de la Sierra round-trip from $374. Another airline that can offer you cheap pricing is Copa Airlines. United Airlines is priced at 61% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Francisco to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from San Francisco to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from San Francisco to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?

    Currently, March is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $356). Flying from San Francisco to Santa Cruz de la Sierra in December is currently the most expensive (average of $1,667). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from San Francisco to Santa Cruz de la Sierra

Discover the top 2 airlines that operate flights from San Francisco to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$374Average$1,022FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$622Average$864FlexibilityNo cancel feeOn-time70%

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