$389+ Cheap flights from San Francisco (SFO) to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — VVI
Jul 8 — Jul 151
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Santa Cruz de la Sierra
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Cheapest flights from San Francisco to Santa Cruz de la SierraExplore the most affordable flight options available from San Francisco to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
Explore the most affordable flight options available from San Francisco to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 8, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:31 am
SFO
- VVI
1 stop18h 13m
Copa Airlines
Mon 11/231:08 am
VVI
- SFO
1 stop20h 17m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$774
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:05 am
SFO
- VVI
2 stops17h 33m
Multiple Airlines
Fri 9/1812:00 pm
VVI
- SFO
2 stops31h 57m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$792
This United deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am
SFO
- VVI
2 stops42h 35m
Multiple Airlines
Mon 11/233:40 am
VVI
- SFO
2 stops31h 40m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$816
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:12 am
SFO
- VVI
1 stop18h 32m
Copa Airlines
Mon 9/1411:47 am
VVI
- SFO
1 stop14h 53m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$822
This BusinessClass deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:45 am
SFO
- VVI
2 stops18h 53m
Multiple Airlines
Fri 6/1912:05 pm
VVI
- SFO
2 stops40h 10m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$823
This United deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:49 pm
SFO
- VVI
2 stops23h 55m
Multiple Airlines
Sun 9/133:35 am
VVI
- SFO
2 stops34h 07m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:49 pm
SFO
- VVI
2 stops23h 51m
United Airlines
Thu 8/2711:47 am
VVI
- SFO
2 stops26h 16m
United Airlines
Deal found 6/4![United Airlines logo]()
$829
This KAYAK deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:45 am
SFO
- VVI
2 stops18h 55m
Copa Airlines
Tue 8/1811:47 am
VVI
- SFO
2 stops24h 43m
Copa Airlines
Deal found 6/6![Copa Airlines logo]()
$836
This United deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
SFO
- VVI
2 stops18h 30m
Multiple Airlines
Mon 6/83:35 am
VVI
- SFO
2 stops19h 35m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$850
This United deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:59 pm
SFO
- VVI
2 stops46h 36m
Multiple Airlines
Wed 12/211:42 am
VVI
- SFO
2 stops33h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$864
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:05 am
SFO
- VVI
2 stops17h 30m
Copa Airlines
Mon 8/1711:47 am
VVI
- SFO
2 stops25h 42m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$883
Best flights from San Francisco to Santa Cruz de la SierraDiscover carefully curated flight deals from San Francisco to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
Discover carefully curated flight deals from San Francisco to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 8, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:31 am
SFO
- VVI
1 stop18h 13m
Copa Airlines
Mon 11/231:08 am
VVI
- SFO
1 stop20h 17m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$774
This United deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:49 pm
SFO
- VVI
2 stops23h 55m
Multiple Airlines
Sun 9/133:35 am
VVI
- SFO
2 stops34h 07m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$827
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:00 pm
SFO
- VVI
2 stops29h 44m
United Airlines
Mon 9/1411:47 am
VVI
- SFO
3 stops34h 25m
United Airlines
Deal found 6/5![United Airlines logo]()
$829
This FlightHub deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:15 pm
SFO
- VVI
2 stops33h 15m
Avianca
Sat 8/293:35 am
VVI
- SFO
3 stops29h 50m
Avianca
Deal found 6/3![Avianca logo]()
$990
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:12 am
SFO
- VVI
1 stop18h 32m
Copa Airlines
Mon 9/1411:47 am
VVI
- SFO
1 stop14h 53m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$822
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:30 pm
SFO
- VVI
2 stops25h 10m
United Airlines
Thu 8/2711:47 am
VVI
- SFO
2 stops24h 31m
United Airlines
Deal found 6/7![United Airlines logo]()
$829
This United deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:59 pm
SFO
- VVI
2 stops46h 36m
Multiple Airlines
Wed 12/211:42 am
VVI
- SFO
2 stops33h 30m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$864
This Avianca deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:45 am
SFO
- VVI
3 stops39h 45m
Avianca
Wed 8/263:35 am
VVI
- SFO
3 stops53h 50m
Avianca
Deal found 6/7![Avianca logo]()
$1,028
This United deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:31 am
SFO
- VVI
1 stop18h 13m
Multiple Airlines
Mon 11/233:40 am
VVI
- SFO
2 stops17h 32m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$1,097
Last-minute flights from San Francisco to Santa Cruz de la SierraDiscover last-minute flight deals from San Francisco to Santa Cruz de la Sierra. Data last updated June 8, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Santa Cruz de la Sierra. Data last updated June 8, 2026 and is based on user searches.
This United deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
SFO
- VVI
2 stops18h 30m
Multiple Airlines
Mon 6/83:35 am
VVI
- SFO
2 stops19h 35m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$850
This BusinessClass deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:45 am
SFO
- VVI
2 stops18h 53m
Multiple Airlines
Fri 6/1912:05 pm
VVI
- SFO
2 stops40h 10m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$823
This Avianca deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/272:30 am
SFO
- VVI
2 stops21h 00m
Avianca
Fri 7/103:35 am
VVI
- SFO
2 stops23h 20m
Avianca
Deal found 6/5![Avianca logo]()
$1,029
This KAYAK deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2912:45 am
SFO
- VVI
2 stops18h 53m
Copa Airlines
Mon 7/131:12 am
VVI
- SFO
2 stops19h 23m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$962
This Avianca deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/302:15 pm
SFO
- VVI
2 stops33h 15m
Avianca
Tue 7/143:35 am
VVI
- SFO
2 stops22h 00m
Avianca
Deal found 6/5![Avianca logo]()
$1,028
This FlightHub deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:30 am
SFO
- VVI
2 stops21h 00m
Avianca
Sun 7/193:35 am
VVI
- SFO
2 stops22h 00m
Avianca
Deal found 6/4![Avianca logo]()
$973
This FlightHub deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:30 am
SFO
- VVI
2 stops45h 00m
Avianca
Sat 7/183:35 am
VVI
- SFO
3 stops29h 50m
Avianca
Deal found 6/4![Avianca logo]()
$1,008
This Avianca deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:30 am
SFO
- VVI
2 stops21h 00m
Avianca
Sun 8/163:35 am
VVI
- SFO
3 stops29h 50m
Avianca
Deal found 6/5![Avianca logo]()
$1,011
This FlightHub deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:15 pm
SFO
- VVI
2 stops33h 15m
Avianca
Sat 8/293:35 am
VVI
- SFO
3 stops29h 50m
Avianca
Deal found 6/3![Avianca logo]()
$990
One-way flights from San Francisco to Santa Cruz de la SierraSearch for one-way flight options from San Francisco to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
Search for one-way flight options from San Francisco to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated June 8, 2026.
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:00 am
SFO
- VVI
2 stops27h 10m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:38 pm
SFO
- VVI
2 stops29h 57m
United Airlines
Deal found 6/4![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:45 pm
SFO
- VVI
2 stops24h 55m
United Airlines
Deal found 6/5![United Airlines logo]()
$405
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:21 pm
SFO
- VVI
1 stop28h 14m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:38 pm
SFO
- VVI
3 stops31h 02m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$428
This KAYAK deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:45 am
SFO
- VVI
2 stops18h 55m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:23 pm
SFO
- VVI
2 stops47h 17m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$446
This Copa Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/21:12 am
SFO
- VVI
1 stop18h 28m
Copa Airlines
Deal found 6/3![Copa Airlines logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:00 pm
SFO
- VVI
3 stops46h 40m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:00 pm
SFO
- VVI
3 stops44h 40m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$471
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:23 pm
SFO
- VVI
2 stops23h 17m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$499
Find flight deals from San Francisco to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $774 (Copa Airlines) |
One-way from | $389 (KAYAK) |
Popular in | December |
Cheapest in | March |
Average price | $979 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
Use the filters below to find and compare flights from San Francisco to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Sun 10/25
1:31 am-10:44 pm
1 stop18h 13m
Santa Cruz de la Sierra Viru Viru Intl
Mon 11/23
1:08 am-5:25 pm
1 stop20h 17m
$774
Quickest round-trip
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Tue 9/1
1:12 am-10:44 pm
1 stop18h 32m
Santa Cruz de la Sierra Viru Viru Intl
Mon 9/14
11:47 am-11:40 pm
1 stop14h 53m
$822
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Wed 9/2
7:49 pm-10:44 pm
2 stops23h 55m
Santa Cruz de la Sierra Viru Viru Intl
Sun 9/13
3:35 am-10:42 am
2 stops34h 07m
$827
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Wed 9/2
2:00 pm-10:44 pm
2 stops29h 44m
Santa Cruz de la Sierra Viru Viru Intl
Mon 9/14
11:47 am-7:12 pm
3 stops34h 25m
$829
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Mon 8/24
6:30 pm-10:40 pm
2 stops25h 10m
Santa Cruz de la Sierra Viru Viru Intl
Thu 8/27
11:47 am-9:18 am
2 stops24h 31m
$829
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Mon 11/2
11:59 pm-2:35 am
2 stops46h 36m
Santa Cruz de la Sierra Viru Viru Intl
Wed 12/2
11:42 am-5:12 pm
2 stops33h 30m
$864
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Thu 7/30
2:15 pm-2:30 am
2 stops33h 15m
Santa Cruz de la Sierra Viru Viru Intl
Sat 8/29
3:35 am-6:25 am
3 stops29h 50m
$990
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Mon 8/24
7:45 am-2:30 am
3 stops39h 45m
Santa Cruz de la Sierra Viru Viru Intl
Wed 8/26
3:35 am-6:25 am
3 stops53h 50m
$1,028
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Sun 10/25
1:31 am-10:44 pm
1 stop18h 13m
Santa Cruz de la Sierra Viru Viru Intl
Mon 11/23
3:40 am-5:12 pm
2 stops17h 32m
$1,097
Cheapest one-way
San FranciscoSanta Cruz de la Sierra
SFO - VVI
SFOVVI
San Francisco
Tue 8/11
6:38 pm-3:35 am
2 stops29h 57m
$400
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santa Cruz de la Sierra in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from San Francisco with our price prediction graph.
SFO-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Santa Cruz de la Sierra
What is the cheapest month to book a flight from San Francisco to Santa Cruz de la Sierra?
Currently, March is the cheapest month in which you can book a flight from San Francisco to Santa Cruz de la Sierra (average of $356). Flying from San Francisco to Santa Cruz de la Sierra in December is currently the most expensive (average of $1,667). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Santa Cruz de la Sierra?
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 8, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from San Francisco to Santa Cruz de la Sierra by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.5
Entertainment
6.8
Crew
8.1
Boarding
7.7
Food
6.9
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Boarding
7.7
Food
6.9
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Overall
7.5
Entertainment
6.8
Crew
8.1
Boarding
7.7
Food
6.9
Comfort
7.4
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Francisco to Santa Cruz de la Sierra
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Complete your trip
Complete your trip to Santa Cruz de la Sierra by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to Santa Cruz de la Sierra by cabin class
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San Francisco and Santa Cruz de la Sierra flights
Browse other San Francisco and Santa Cruz de la Sierra flight options. Last updated on June 8, 2026.
Other flights from San Francisco
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Francisco to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from San Francisco to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$394 | Average$878 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$622 | Average$864 | FlexibilityNo cancel fee | On-time70% |