South America

$161+ Cheap flights from San Francisco (SFO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
May 28 — Jun 41
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco to South America

Cheapest flights from San Francisco to South America
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:51 am
SFO
-
BOG
2 stops12h 24m
American Airlines
Mon 9/2111:45 pm
BOG
-
SFO
1 stop11h 10m
American Airlines
Deal found 4/24$361
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/812:45 am
SFO
-
BOG
1 stop16h 35m
United Airlines
Thu 9/248:30 am
BOG
-
SFO
1 stop11h 59m
United Airlines
Deal found 4/23$371
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:45 am
SFO
-
MDE
1 stop18h 25m
United Airlines
Thu 8/279:45 am
MDE
-
SFO
1 stop10h 44m
United Airlines
Deal found 4/24$373
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:30 am
SFO
-
MDE
2 stops14h 09m
American Airlines
Wed 12/27:00 am
MDE
-
SFO
1 stop18h 59m
American Airlines
Deal found 4/26$378
This BusinessClass deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/192:08 pm
SFO
-
BOG
2 stops20h 57m
GOL
Wed 9/911:45 pm
BOG
-
SFO
1 stop11h 10m
GOL
Deal found 4/27$378
This BusinessClass deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:40 pm
SFO
-
MDE
2 stops21h 08m
GOL
Wed 6/31:53 pm
MDE
-
SFO
2 stops23h 02m
GOL
Deal found 4/25$380
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:45 am
SFO
-
BOG
1 stop26h 09m
United Airlines
Mon 9/218:30 am
BOG
-
SFO
1 stop17h 46m
United Airlines
Deal found 4/24$380
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:54 pm
SFO
-
MDE
1 stop24h 16m
United Airlines
Thu 8/279:45 am
MDE
-
SFO
1 stop16h 31m
United Airlines
Deal found 4/24$382
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:59 pm
SFO
-
BOG
1 stop20h 39m
American Airlines
Fri 5/222:10 pm
BOG
-
SFO
1 stop22h 44m
American Airlines
Deal found 4/24$382
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:59 am
SFO
-
BOG
1 stop19h 31m
American Airlines
Sat 5/236:30 am
BOG
-
SFO
1 stop19h 29m
American Airlines
Deal found 4/23$383
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:20 pm
SFO
-
BOG
1 stop20h 20m
Delta
Fri 9/1810:35 am
BOG
-
SFO
2 stops15h 27m
Delta
Deal found 4/23$386
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:59 pm
SFO
-
BOG
1 stop11h 41m
Delta
Thu 5/288:40 am
BOG
-
SFO
2 stops14h 24m
Delta
Deal found 4/24$387

Find flight deals from San Francisco to South America

Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated April 28, 2026.

Round-trip from

$361
(American Airlines)

One-way from

$161
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$522
From San Francisco to South America
One-way flight from San Francisco to South America
Highest demand for flights based on searches. 18% potential increase in price ($121 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 9/10

12:45 am-7:20 pm

1 stop16h 35m

Bogotá El Dorado

Sat 9/19

8:30 am-6:29 pm

1 stop11h 59m

$371

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Sun 5/10

7:15 am-4:54 am

1 stop19h 39m

Bogotá El Dorado

Wed 5/13

8:30 am-11:59 pm

1 stop17h 29m

$371

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 9/7

12:45 am-4:54 am

1 stop26h 09m

Bogotá El Dorado

Mon 9/21

8:30 am-12:16 am

1 stop17h 46m

$380
Quickest round-trip

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Fri 9/25

4:10 pm-4:54 am

1 stop10h 44m

Bogotá El Dorado

Sat 10/10

8:30 am-7:24 pm

1 stop12h 54m

$383

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Mon 5/11

11:59 pm-5:50 pm

2 stops15h 51m

Bogotá El Dorado

Tue 6/2

10:35 am-10:23 pm

2 stops13h 48m

$387

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 5/12

11:59 pm-8:10 pm

2 stops18h 11m

Bogotá El Dorado

Tue 8/11

2:55 pm-10:12 am

1 stop21h 17m

$400

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 9/8

6:00 am-7:15 pm

1 stop11h 15m

Bogotá El Dorado

Mon 9/21

11:00 am-12:02 am

2 stops15h 02m

$400

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 9/23

3:30 pm-1:40 pm

1 stop20h 10m

Bogotá El Dorado

Sat 9/26

11:00 am-10:01 am

2 stops25h 01m

$400

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Tue 9/8

11:59 pm-7:20 pm

1 stop17h 21m

Bogotá El Dorado

Fri 9/11

7:20 am-11:18 am

1 stop29h 58m

$419

San FranciscoMedellín

SFO - MDE

SFOMDE

San Francisco

Sun 5/10

12:45 am-9:10 pm

1 stop18h 25m

Medellín Jose Maria Cordova Intl

Thu 5/14

9:45 am-11:59 pm

1 stop16h 14m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from San Francisco to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South America

How far ahead should I book a flight from San Francisco to South America?

Booking 2 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to South America?

Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $576). Flying from San Francisco to South America in December is currently the most expensive (average of $1,011). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 28, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,LATAM Airlines, andUnited Airlines from San Francisco to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Entertainment

6.8

Crew

8.1

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Francisco to South America?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to South America. San Francisco is conveniently located just 11.0 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to South America?

    Airlines like United Airlines, Delta, and Copa Airlines fly from San Francisco to South America in about 15h 51m. The time it takes to get you to your destination can typically vary by up to 5h 52m. The distance from San Francisco to South America is about 3786 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Francisco to South America one-way?

    $147 is the cheapest one-way deal found within the past few days, from United Airlines. You may also be able to find cheap deals on Avianca and JetBlue, with prices starting from $148 and $160, respectively.

  • What are the most popular routes from San Francisco to South America?

  • Can I find deals for flights from San Francisco to South America that include hotel bookings?

    Yes. In addition to deals on San Francisco to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South America.

  • Can I find deals for business class flights from San Francisco to South America?

    Yes. Cheapflights offers flight deals from San Francisco to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South America?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to South America (average of $576). Flying from San Francisco to South America in December is currently the most expensive (average of $1,011). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 10 airlines flying from San Francisco to South America

Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$214Average$761FlexibilityNo cancel feeOn-time69%
DeltaCheapest$223Average$818FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$234Average$794FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$270Average$752FlexibilityNo cancel feeOn-time70%
AviancaCheapest$290Average$650FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$292Average$734FlexibilityNo cancel feeOn-time62%
GOLCheapest$415Average$1,255FlexibilityNo cancel feeOn-time74%
American AirlinesCheapest$459Average$906FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$576Average$825FlexibilityNo cancel feeOn-time67%
AeromexicoCheapest$602Average$1,114FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.