$218+ Cheap flights from San Francisco (SFO) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
Aug 26 — Sep 21
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to South America with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to South AmericaExplore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
This lol.travel deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:40 pm
SFO
- CTG
1 stop10h 55m
JetBlue
Thu 9/312:35 pm
CTG
- SFO
1 stop13h 16m
JetBlue
Deal found 7/25![JetBlue logo]()
$482
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:35 pm
SFO
- CTG
1 stop13h 00m
American Airlines
Fri 9/41:35 pm
CTG
- SFO
1 stop13h 19m
American Airlines
Deal found 7/27![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:59 pm
SFO
- CTG
1 stop11h 36m
American Airlines
Fri 10/231:35 pm
CTG
- SFO
1 stop12h 24m
American Airlines
Deal found 7/27![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:01 pm
SFO
- CTG
2 stops20h 34m
American Airlines
Sun 10/181:35 pm
CTG
- SFO
2 stops21h 22m
American Airlines
Deal found 7/26![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:46 pm
SFO
- CTG
1 stop12h 49m
American Airlines
Mon 10/191:35 pm
CTG
- SFO
1 stop22h 54m
American Airlines
Deal found 7/26![American Airlines logo]()
$513
This BusinessClass deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/81:27 pm
SFO
- CTG
2 stops21h 08m
GOL
Tue 10/131:35 pm
CTG
- SFO
2 stops21h 22m
GOL
Deal found 7/26![GOL logo]()
$526
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:54 pm
SFO
- CTG
1 stop12h 41m
American Airlines
Sat 10/311:35 pm
CTG
- SFO
1 stop12h 24m
American Airlines
Deal found 7/23![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:35 pm
SFO
- CTG
1 stop14h 40m
American Airlines
Sun 8/303:15 pm
CTG
- SFO
2 stops22h 11m
American Airlines
Deal found 7/23![American Airlines logo]()
$534
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:30 pm
SFO
- CTG
2 stops12h 45m
American Airlines
Thu 9/33:15 pm
CTG
- SFO
2 stops20h 48m
American Airlines
Deal found 7/25![American Airlines logo]()
$538
This Gotogate deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:21 pm
SFO
- BOG
1 stop18h 46m
Copa Airlines
Sun 8/304:59 am
BOG
- SFO
1 stop20h 41m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$544
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:27 am
SFO
- CTG
1 stop23h 08m
American Airlines
Tue 9/291:35 pm
CTG
- SFO
1 stop12h 24m
American Airlines
Deal found 7/24![American Airlines logo]()
$544
This KAYAK deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:10 pm
SFO
- CTG
1 stop10h 20m
JetBlue
Sat 10/2412:35 pm
CTG
- SFO
1 stop12h 42m
JetBlue
Deal found 7/24![JetBlue logo]()
$545
Best flights from San Francisco to South AmericaDiscover carefully curated flight deals from San Francisco to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated flight deals from San Francisco to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This lol.travel deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:40 pm
SFO
- CTG
1 stop10h 55m
JetBlue
Thu 9/312:35 pm
CTG
- SFO
1 stop13h 16m
JetBlue
Deal found 7/25![JetBlue logo]()
$482
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:59 pm
SFO
- CTG
1 stop11h 36m
American Airlines
Fri 10/231:35 pm
CTG
- SFO
1 stop12h 24m
American Airlines
Deal found 7/27![American Airlines logo]()
$499
This Copa Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:36 pm
SFO
- BOG
1 stop25h 44m
Copa Airlines
Sun 11/810:00 am
BOG
- SFO
1 stop10h 25m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:15 am
SFO
- BOG
1 stop13h 20m
United Airlines
Sun 11/88:15 am
BOG
- SFO
1 stop18h 49m
United Airlines
Deal found 7/24![United Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:55 pm
SFO
- BOG
1 stop19h 20m
Delta
Sat 10/1011:00 am
BOG
- SFO
2 stops23h 54m
Delta
Deal found 7/23![Delta logo]()
$568
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:15 pm
SFO
- MDE
2 stops15h 20m
Avianca
Wed 9/29:30 am
MDE
- SFO
2 stops15h 05m
Avianca
Deal found 7/26![Avianca logo]()
$624
This KAYAK deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:23 pm
SFO
- CTG
2 stops22h 12m
GOL
Sat 8/223:15 pm
CTG
- SFO
1 stop11h 39m
GOL
Deal found 7/22![GOL logo]()
$695
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:30 pm
SFO
- SCL
2 stops25h 05m
LATAM Airlines
Tue 11/175:55 pm
SCL
- SFO
2 stops22h 06m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$786
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:57 pm
SFO
- CTG
2 stops14h 38m
American Airlines
Sat 10/241:35 pm
CTG
- SFO
2 stops21h 26m
American Airlines
Deal found 7/24![American Airlines logo]()
$504
This Justfly.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:30 pm
SFO
- SDU
2 stops20h 55m
Azul
Sat 11/76:50 pm
SDU
- SFO
2 stops22h 04m
Azul
Deal found 7/23![Azul logo]()
$1,058
This Flysmarter deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:54 pm
SFO
- SDU
2 stops22h 51m
Lufthansa
Wed 9/21:45 pm
SDU
- SFO
2 stops24h 57m
Lufthansa
Deal found 7/26![Lufthansa logo]()
$1,064
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/161:12 am
SFO
- SDU
2 stops25h 53m
Multiple Airlines
Wed 9/27:50 am
SDU
- SFO
3 stops33h 00m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$1,066
This Copa Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:21 pm
SFO
- BOG
1 stop11h 47m
Copa Airlines
Mon 9/217:00 am
BOG
- SFO
1 stop18h 40m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:40 pm
SFO
- BOG
1 stop10h 14m
United Airlines
Mon 9/218:30 am
BOG
- SFO
1 stop11h 59m
United Airlines
Deal found 7/24![United Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:30 pm
SFO
- BOG
2 stops16h 20m
Delta
Mon 9/2111:00 am
BOG
- SFO
2 stops14h 40m
Delta
Deal found 7/22![Delta logo]()
$568
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:30 pm
SFO
- CTG
2 stops12h 45m
American Airlines
Thu 9/33:15 pm
CTG
- SFO
2 stops20h 48m
American Airlines
Deal found 7/25![American Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:40 pm
SFO
- BOG
1 stop10h 14m
United Airlines
Thu 8/2712:14 am
BOG
- SFO
1 stop14h 00m
United Airlines
Deal found 7/24![United Airlines logo]()
$563
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:12 am
SFO
- BOG
2 stops15h 38m
Delta
Sat 9/1211:00 am
BOG
- SFO
2 stops23h 29m
Delta
Deal found 7/22![Delta logo]()
$568
This Avianca deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:55 pm
SFO
- MDE
2 stops14h 55m
Avianca
Mon 9/2810:15 am
MDE
- SFO
2 stops14h 20m
Avianca
Deal found 7/22![Avianca logo]()
$625
This Copa Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:12 am
SFO
- BOG
1 stop14h 14m
Copa Airlines
Sun 9/134:59 am
BOG
- SFO
1 stop20h 41m
Copa Airlines
Deal found 7/27![Copa Airlines logo]()
$571
This JetBlue deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:10 pm
SFO
- CTG
1 stop11h 42m
JetBlue
Wed 9/232:00 pm
CTG
- SFO
1 stop11h 17m
JetBlue
Deal found 7/22![JetBlue logo]()
$637
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:45 pm
SFO
- BOG
2 stops18h 45m
Delta
Mon 11/23:55 pm
BOG
- SFO
2 stops21h 59m
Delta
Deal found 7/22![Delta logo]()
$568
This Avianca deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:15 pm
SFO
- MDE
2 stops14h 05m
Avianca
Mon 9/219:05 pm
MDE
- SFO
2 stops17h 45m
Avianca
Deal found 7/22![Avianca logo]()
$625
This Copa Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:21 pm
SFO
- BOG
1 stop12h 45m
Copa Airlines
Sun 8/234:59 am
BOG
- SFO
1 stop20h 41m
Copa Airlines
Deal found 7/22![Copa Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:40 pm
SFO
- BOG
1 stop10h 14m
United Airlines
Tue 8/258:30 am
BOG
- SFO
1 stop15h 15m
United Airlines
Deal found 7/26![United Airlines logo]()
$573
This GOL deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:35 am
SFO
- GIG
1 stop19h 50m
GOL
Tue 12/15:05 pm
GIG
- SFO
2 stops27h 00m
GOL
Deal found 7/25![GOL logo]()
$759
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:27 am
SFO
- CTG
1 stop23h 08m
American Airlines
Tue 9/291:35 pm
CTG
- SFO
2 stops22h 37m
American Airlines
Deal found 7/27![American Airlines logo]()
$641
This JetBlue deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:10 pm
SFO
- CTG
1 stop11h 42m
JetBlue
Wed 9/162:00 pm
CTG
- SFO
1 stop11h 17m
JetBlue
Deal found 7/26![JetBlue logo]()
$718
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:45 am
SFO
- MDE
1 stop18h 25m
United Airlines
Fri 11/1310:40 am
MDE
- SFO
1 stop10h 52m
United Airlines
Deal found 7/23![United Airlines logo]()
$619
This Copa Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:21 pm
SFO
- MDE
1 stop22h 14m
Copa Airlines
Wed 9/239:15 am
MDE
- SFO
1 stop16h 25m
Copa Airlines
Deal found 7/26![Copa Airlines logo]()
$627
Last-minute flights from San Francisco to South AmericaDiscover last-minute flight deals from San Francisco to South America. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to South America. Data last updated July 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:54 pm
SFO
- BOG
1 stop22h 26m
United Airlines
Fri 8/2812:14 am
BOG
- SFO
1 stop14h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$575
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:45 am
SFO
- BOG
2 stops16h 15m
Avianca
Thu 8/209:05 am
BOG
- SFO
1 stop16h 50m
Avianca
Deal found 7/26![Avianca logo]()
$565
This Copa Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:21 pm
SFO
- BOG
1 stop11h 49m
Copa Airlines
Tue 8/2512:08 pm
BOG
- SFO
1 stop13h 32m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$572
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:59 pm
SFO
- BOG
1 stop17h 21m
United Airlines
Tue 9/2912:14 am
BOG
- SFO
1 stop13h 30m
United Airlines
Deal found 7/24![United Airlines logo]()
$563
This Gotogate deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:21 pm
SFO
- BOG
1 stop18h 46m
Copa Airlines
Sun 8/304:59 am
BOG
- SFO
1 stop20h 41m
Copa Airlines
Deal found 7/23![Copa Airlines logo]()
$544
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:59 pm
SFO
- BOG
1 stop17h 21m
United Airlines
Wed 8/268:30 am
BOG
- SFO
1 stop13h 40m
United Airlines
Deal found 7/26![United Airlines logo]()
$573
This lol.travel deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:40 pm
SFO
- CTG
1 stop10h 55m
JetBlue
Thu 9/312:35 pm
CTG
- SFO
1 stop13h 16m
JetBlue
Deal found 7/25![JetBlue logo]()
$482
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:30 pm
SFO
- CTG
2 stops12h 45m
American Airlines
Thu 9/33:15 pm
CTG
- SFO
2 stops20h 48m
American Airlines
Deal found 7/25![American Airlines logo]()
$538
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:05 pm
SFO
- BOG
1 stop19h 35m
Delta
Fri 8/2811:00 am
BOG
- SFO
2 stops23h 01m
Delta
Deal found 7/22![Delta logo]()
$568
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:35 pm
SFO
- CTG
1 stop13h 00m
American Airlines
Fri 9/41:35 pm
CTG
- SFO
1 stop13h 19m
American Airlines
Deal found 7/27![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:35 pm
SFO
- CTG
1 stop14h 40m
American Airlines
Sun 8/303:15 pm
CTG
- SFO
2 stops22h 11m
American Airlines
Deal found 7/23![American Airlines logo]()
$534
This Avianca deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:45 am
SFO
- BOG
2 stops16h 15m
Avianca
Sat 9/129:05 am
BOG
- SFO
1 stop15h 30m
Avianca
Deal found 7/26![Avianca logo]()
$566
One-way flights from San Francisco to South AmericaSearch for one-way flight options from San Francisco to South America. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way flight options from San Francisco to South America. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:10 pm
SFO
- CTG
1 stop11h 42m
JetBlue
Deal found 7/22![JetBlue logo]()
$218
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:31 pm
SFO
- CTG
2 stops18h 04m
American Airlines
Deal found 7/26![American Airlines logo]()
$223
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:31 pm
SFO
- CTG
2 stops19h 44m
American Airlines
Deal found 7/25![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:02 pm
SFO
- CTG
2 stops15h 33m
American Airlines
Deal found 7/23![American Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:56 pm
SFO
- MDE
3 stops33h 19m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:23 pm
SFO
- CTG
3 stops42h 10m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:04 pm
SFO
- MDE
3 stops22h 36m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$270
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:54 pm
SFO
- BOG
1 stop32h 00m
United Airlines
Deal found 7/24![United Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:23 pm
SFO
- MDE
3 stops42h 13m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:49 pm
SFO
- BOG
1 stop21h 28m
American Airlines
Deal found 7/22![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:30 am
SFO
- BOG
1 stop15h 04m
American Airlines
Deal found 7/26![American Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:18 am
SFO
- BOG
2 stops24h 49m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$275
Find flight deals from San Francisco to South America
Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated July 27, 2026.
Round-trip from | $482 (lol.travel) |
|---|---|
One-way from | $218 |
Popular in | December |
Cheapest in | April |
Average price | $647 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoCartagena
SFO - CTG
SFOCTG
San Francisco
Fri 8/21
10:40 pm-11:35 am
1 stop10h 55m
Cartagena Rafael Nunez
Thu 9/3
12:35 pm-11:51 pm
1 stop13h 16m
$482
San FranciscoCartagena
SFO - CTG
SFOCTG
San Francisco
Sun 10/18
10:59 pm-12:35 pm
1 stop11h 36m
Cartagena Rafael Nunez
Fri 10/23
1:35 pm-11:59 pm
1 stop12h 24m
$499
San FranciscoCartagena
SFO - CTG
SFOCTG
San Francisco
Sat 10/17
7:57 pm-12:35 pm
2 stops14h 38m
Cartagena Rafael Nunez
Sat 10/24
1:35 pm-9:01 am
2 stops21h 26m
$504
San FranciscoCartagena
SFO - CTG
SFOCTG
San Francisco
Fri 8/21
11:30 pm-2:15 pm
2 stops12h 45m
Cartagena Rafael Nunez
Thu 9/3
3:15 pm-10:03 am
2 stops20h 48m
$538
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Thu 10/29
8:36 pm-12:20 am
1 stop25h 44m
Bogotá El Dorado
Sun 11/8
10:00 am-5:25 pm
1 stop10h 25m
$551
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Thu 9/17
8:21 pm-10:08 am
1 stop11h 47m
Bogotá El Dorado
Mon 9/21
7:00 am-11:40 pm
1 stop18h 40m
$551
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Thu 10/29
7:15 am-10:35 pm
1 stop13h 20m
Bogotá El Dorado
Sun 11/8
8:15 am-12:04 am
1 stop18h 49m
$563
Quickest round-trip
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Tue 9/8
4:40 pm-4:54 am
1 stop10h 14m
Bogotá El Dorado
Mon 9/21
8:30 am-6:29 pm
1 stop11h 59m
$563
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Fri 8/21
4:40 pm-4:54 am
1 stop10h 14m
Bogotá El Dorado
Thu 8/27
12:14 am-12:14 pm
1 stop14h 00m
$563
San FranciscoBogotá
SFO - BOG
SFOBOG
San Francisco
Fri 9/25
9:55 pm-7:15 pm
1 stop19h 20m
Bogotá El Dorado
Sat 10/10
11:00 am-8:54 am
2 stops23h 54m
$568
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
SFO-CTG
SFO-BOG
SFO-MDE
SFO-SCL
SFO-SDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South America
SFO-0SA
SFO-CTG
SFO-BOG
SFO-MDE
SFO-SCL
What is the cheapest month to book a flight from San Francisco to South America?
Currently, September is the cheapest month in which you can book a flight from San Francisco to South America (average of $657). Flying from San Francisco to South America in December is currently the most expensive (average of $1,045). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Francisco to South America?
Booking 2 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to South America. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 27, 2026.
Peruse reviews from past customers who have flown with Copa Airlines,LATAM Airlines, andUnited Airlines from San Francisco to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Comfort
7.4
Food
6.9
Crew
8.1
Overall
7.6
Boarding
7.8
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Francisco to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to South America by cabin class
Find flights from San Francisco to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and South America flights
Browse other San Francisco and South America flight options. Last updated on July 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
San Francisco to South America flights
Consider these flights traveling from San Francisco to South America.
Top 10 airlines flying from San Francisco to South America
Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$214 | Average$805 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$223 | Average$839 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$233 | Average$809 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$284 | Average$710 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$292 | Average$663 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$302 | Average$826 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$448 | Average$923 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$482 | Average$1,056 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$499 | Average$1,238 | FlexibilityNo cancel fee | On-time74% | |
| Cheapest$661 | Average$1,293 | FlexibilityNo cancel fee | On-timeN/A |