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South America

$155+ Cheap flights from San Francisco (SFO) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — BOG
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from San Francisco to South America

Cheapest flights from San Francisco to South America
Explore the most affordable flight options available from San Francisco to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:20 amSFO - BOG
1 stop12h 15mUnited Airlines
Tue 12/98:15 amBOG - SFO
1 stop12h 31mUnited Airlines
Deal found 12/2$466
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:00 amSFO - SCL
1 stop22h 50mUnited Airlines
Wed 12/2410:45 pmSCL - SFO
1 stop21h 06mUnited Airlines
Deal found 12/3$494
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:59 pmSFO - BOG
1 stop19h 36mUnited Airlines
Thu 12/118:15 amBOG - SFO
1 stop11h 31mUnited Airlines
Deal found 12/4$496
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:00 amSFO - SCL
2 stops18h 10mAmerican Airlines
Wed 12/1711:15 pmSCL - SFO
2 stops21h 32mAmerican Airlines
Deal found 12/4$499
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:59 pmSFO - BOG
1 stop20h 31mAmerican Airlines
Tue 2/311:55 pmBOG - SFO
1 stop14h 03mAmerican Airlines
Deal found 12/3$503
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:15 amSFO - SCL
1 stop16h 35mUnited Airlines
Tue 12/2310:45 pmSCL - SFO
1 stop16h 05mUnited Airlines
Deal found 12/3$504
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:42 pmSFO - MDE
1 stop12h 00mUnited Airlines
Tue 12/161:15 amMDE - SFO
1 stop19h 31mUnited Airlines
Deal found 12/4$506
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:10 pmSFO - BOG
1 stop31h 00mUnited Airlines
Wed 12/108:15 amBOG - SFO
1 stop17h 44mUnited Airlines
Deal found 12/2$508
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amSFO - SCL
1 stop20h 45mAmerican Airlines
Tue 12/1611:15 pmSCL - SFO
2 stops18h 06mAmerican Airlines
Deal found 12/4$509
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:02 amSFO - MDE
1 stop12h 37mAmerican Airlines
Wed 12/177:00 amMDE - SFO
2 stops16h 56mAmerican Airlines
Deal found 12/3$511
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:20 amSFO - SCL
1 stop20h 30mUnited Airlines
Sat 12/2010:45 pmSCL - SFO
1 stop25h 14mUnited Airlines
Deal found 12/3$514
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/41:01 pmSFO - MDE
1 stop30h 04mUnited Airlines
Wed 12/101:15 amMDE - SFO
1 stop19h 31mUnited Airlines
Deal found 12/3$517

Find flight deals from San Francisco to South America

Keep the following information in mind while searching for San Francisco to South America flight deals. Data was last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$454
(Delta)

One-way from

$155
(Kiwi.com)

Popular in

December

Cheapest in

March

Average price

$1,004
Provider with most accurate pricing for San Francisco-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Sao Paulo (SAO) flights.
Search Deals
From San Francisco to South America
Search Deals
One-way flight from San Francisco to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from San Francisco to South America that are best for you.

Fly from

San Francisco

Fly to

South America

Route

Depart

Return

Price

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 2/5

6:45 pm-4:45 pm

2 stops19h 00m

Bogotá El Dorado

Mon 2/23

3:55 pm-10:34 am

1 stop21h 39m

$454

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 2/5

6:45 pm-4:45 pm

2 stops19h 00m

Bogotá El Dorado

Thu 2/19

9:00 am-7:54 pm

1 stop13h 54m

$454

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 1/22

12:10 pm-4:45 pm

2 stops25h 35m

Bogotá El Dorado

Wed 2/4

7:00 am-8:25 pm

2 stops16h 25m

$456

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 2/25

2:49 pm-5:10 am

1 stop11h 21m

Bogotá El Dorado

Tue 3/31

8:30 am-6:47 pm

1 stop12h 17m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 1/21

11:59 pm-10:35 pm

1 stop19h 36m

Bogotá El Dorado

Wed 1/28

8:15 am-5:50 pm

1 stop12h 35m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Fri 1/23

7:18 am-10:35 pm

1 stop12h 17m

Bogotá El Dorado

Sun 2/8

8:15 am-5:50 pm

1 stop12h 35m

$459

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 1/22

9:30 pm-7:30 pm

1 stop19h 00m

Bogotá El Dorado

Sun 2/8

5:00 am-11:25 pm

2 stops21h 25m

$463

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Fri 1/23

11:05 pm-4:45 pm

2 stops14h 40m

Bogotá El Dorado

Sat 2/7

5:00 am-11:25 pm

2 stops21h 25m

$468

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Thu 1/22

10:54 pm-4:45 pm

2 stops14h 51m

Bogotá El Dorado

Thu 1/29

7:00 am-11:25 pm

2 stops19h 25m

$468

San FranciscoBogotá

SFO - BOG

SFOBOG

San Francisco

Wed 1/21

10:00 pm-4:45 pm

2 stops15h 45m

Bogotá El Dorado

Mon 1/26

3:55 pm-10:30 am

1 stop21h 35m

$468

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 60 results
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Best time to book a flight from San Francisco to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to South America

What is the cheapest month to book a flight from San Francisco to South America?

Currently, October is the cheapest month in which you can book a flight from San Francisco to South America (average of $222). Flying from San Francisco to South America in December is currently the most expensive (average of $399). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to SA?

Find hourly flight availability from San Francisco to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s optimal to fly from San Francisco to South America in the afternoon. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the evening.

What is the cheapest day to fly from San Francisco to South America?

Use this chart to determine the cheapest time to fly round-trip from San Francisco to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Francisco to South America flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 4, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, LATAM Airlines, and United Airlines from San Francisco to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,890 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,066 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
11,044 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,479 reviews
Copa Airlines
7.6
Good
1,556 reviews

Crew

8.1

Food

6.9

Boarding

7.8

Overall

7.6

Entertainment

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from San Francisco to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Francisco to South America?

    Most people fly from San Francisco (SFO) if they book a flight from San Francisco to South America. San Francisco is conveniently located just 11.8 mi from San Francisco’s city center.

  • How long is the flight from San Francisco to South America?

    Airlines like Delta, United Airlines, and Avianca fly from San Francisco to South America in about 11h 21m. The time it takes to get you to your destination can typically vary by up to 7h 39m. The distance from San Francisco to South America is about 3786 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Francisco to South America one-way?

    $173 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from $178 and $191, respectively.

  • What are the most popular routes from San Francisco to South America?

    While some choose either San Francisco - Sao Paulo Guarulhos Intl or San Francisco - Rio de Janeiro–Galeão Intl, San Francisco - Lima J Chavez Intl is the most popular route from San Francisco to South America.

  • Can I find deals for flights from San Francisco to South America that include hotel bookings?

    Yes. In addition to deals on San Francisco to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to South America.

  • Can I find deals for business class flights from San Francisco to South America?

    Yes. Cheapflights offers flight deals from San Francisco to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to South America?

    Currently, October is the cheapest month in which you can book a flight from San Francisco to South America (average of $222). Flying from San Francisco to South America in December is currently the most expensive (average of $399). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from San Francisco to South America

Discover the top 10 airlines that operate flights from San Francisco to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$366Average$836FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$381Average$670FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$392Average$804FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$402Average$772FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$409Average$653FlexibilityNo cancel feeOn-time62%
LATAM AirlinesCheapest$420Average$835FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$463Average$894FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$531Average$726FlexibilityNo cancel feeOn-time67%
AeromexicoCheapest$652Average$1,055FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$747Average$1,663FlexibilityNo cancel feeOn-time74%

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