$226+ Cheap flights from San Francisco (SFO) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GYE
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Guayaquil
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Best
Last-minute
One-way
Cheapest flights from San Francisco to GuayaquilExplore the most affordable flight options available from San Francisco to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from San Francisco to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:10 pm -
1 stop14h 14m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$589
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:47 am -
2 stops13h 52m
Sun 10/252:29 pm -
1 stop22h 00m
Deal found 9/5![American Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 pm -
1 stop13h 00m
Sun 10/258:23 am -
1 stop17h 17m
Deal found 9/10![Copa Airlines logo]()
$608
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2310:35 pm -
1 stop14h 59m
Wed 12/26:00 pm -
1 stop20h 51m
Deal found 9/8![JetBlue logo]()
$609
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:18 pm -
1 stop18h 37m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$611
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:21 pm -
1 stop13h 00m
Sun 10/184:14 am -
1 stop21h 26m
Deal found 9/9![Copa Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops14h 39m
Wed 10/216:00 am -
1 stop19h 59m
Deal found 9/9![American Airlines logo]()
$625
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:18 pm -
1 stop18h 37m
Thu 10/224:55 pm -
1 stop18h 30m
Deal found 9/10![JetBlue logo]()
$631
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:15 pm -
2 stops16h 40m
Sun 10/257:35 pm -
2 stops19h 20m
Deal found 9/10![Avianca logo]()
$639
This BusinessClass deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:11 am -
2 stops20h 28m
Wed 10/146:00 am -
2 stops19h 06m
Deal found 9/6![GOL logo]()
$653
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:35 pm -
1 stop13h 59m
Mon 11/236:00 am -
1 stop21h 58m
Deal found 9/6![American Airlines logo]()
$666
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:51 pm -
2 stops40h 30m
Thu 10/228:24 am -
1 stop11h 46m
Deal found 9/9![Multiple Airlines logo]()
$672
Best flights from San Francisco to GuayaquilDiscover carefully curated flight deals from San Francisco to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from San Francisco to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:10 pm -
1 stop14h 14m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$589
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:47 am -
2 stops13h 52m
Sun 10/252:29 pm -
1 stop22h 00m
Deal found 9/5![American Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:21 pm -
1 stop13h 00m
Wed 10/218:24 am -
1 stop11h 46m
Deal found 9/9![Copa Airlines logo]()
$608
This Avianca deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:55 pm -
2 stops15h 40m
Sun 10/259:15 pm -
2 stops17h 40m
Deal found 9/5![Avianca logo]()
$639
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:59 pm -
2 stops20h 41m
Tue 12/112:22 pm -
2 stops22h 08m
Deal found 9/9![United Airlines logo]()
$809
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 pm -
1 stop13h 00m
Sun 10/258:23 am -
1 stop17h 17m
Deal found 9/5![Copa Airlines logo]()
$608
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:44 pm -
1 stop13h 21m
Thu 10/224:55 pm -
1 stop18h 30m
Deal found 9/9![JetBlue logo]()
$752
This JetBlue deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:10 pm -
1 stop14h 14m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/9![JetBlue logo]()
$789
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:10 pm -
1 stop14h 14m
Thu 10/224:55 pm -
1 stop18h 30m
Deal found 9/10![JetBlue logo]()
$809
Last-minute flights from San Francisco to GuayaquilDiscover last-minute flight deals from San Francisco to Guayaquil. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Guayaquil. Data last updated September 10, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:18 pm -
1 stop18h 37m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$611
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:18 pm -
1 stop18h 37m
Thu 10/224:55 pm -
1 stop18h 30m
Deal found 9/10![JetBlue logo]()
$631
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:51 pm -
2 stops40h 30m
Thu 10/228:24 am -
1 stop11h 46m
Deal found 9/9![Multiple Airlines logo]()
$672
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:21 pm -
1 stop13h 00m
Sun 10/184:14 am -
1 stop21h 26m
Deal found 9/9![Copa Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
2 stops14h 39m
Wed 10/216:00 am -
1 stop19h 59m
Deal found 9/9![American Airlines logo]()
$625
This BusinessClass deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:11 am -
2 stops20h 28m
Wed 10/146:00 am -
2 stops19h 06m
Deal found 9/6![GOL logo]()
$653
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:10 pm -
1 stop14h 14m
Tue 10/201:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$589
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:10 pm -
1 stop14h 14m
Mon 10/194:55 pm -
1 stop18h 30m
Deal found 9/10![JetBlue logo]()
$609
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:10 pm -
1 stop14h 14m
Fri 10/231:30 pm -
1 stop12h 37m
Deal found 9/10![JetBlue logo]()
$674
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:47 am -
2 stops13h 52m
Sun 10/252:29 pm -
1 stop22h 00m
Deal found 9/5![American Airlines logo]()
$607
This Copa Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:21 pm -
1 stop13h 00m
Sun 10/258:23 am -
1 stop17h 17m
Deal found 9/10![Copa Airlines logo]()
$608
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:15 pm -
2 stops16h 40m
Sun 10/257:35 pm -
2 stops19h 20m
Deal found 9/10![Avianca logo]()
$639
One-way flights from San Francisco to GuayaquilSearch for one-way flight options from San Francisco to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from San Francisco to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This JetBlue deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2311:59 pm -
1 stop13h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![JetBlue logo]()
$226
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2011:59 pm -
1 stop13h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![JetBlue logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:19 pm -
3 stops47h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:53 pm -
3 stops27h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:30 am -
2 stops21h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:59 pm -
2 stops21h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2210:45 pm -
2 stops30h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$384
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:21 pm -
1 stop22h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/14:35 pm -
2 stops18h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$394
Find flight deals from San Francisco to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $584 (American Airlines) |
One-way from | $351 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $550 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Sat 1/23
11:59 pm-4:35 pm
1 stop13h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$226
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Mon 2/8
11:59 pm-4:35 pm
1 stop13h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$226
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Sun 1/17
11:59 pm-4:35 pm
1 stop13h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$226
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Wed 1/20
11:59 pm-4:35 pm
1 stop13h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$308
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Mon 2/8
11:05 am-8:02 am
2 stops17h 57m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Mon 3/1
11:05 am-8:02 am
2 stops17h 57m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Wed 1/20
11:35 am-8:02 am
2 stops17h 27m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Sun 1/17
6:00 am-8:02 am
2 stops23h 02m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Sun 2/7
7:00 am-8:02 am
2 stops22h 02m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$378
San FranciscoGuayaquil
SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo
SFOGYE
San Francisco
Wed 9/16
11:59 pm-11:37 pm
2 stops21h 38m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$380
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on San Francisco-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Francisco with our price prediction graph.
SFO-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Guayaquil
How far ahead should I book a flight from San Francisco to Guayaquil?
Booking 2 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Francisco to Guayaquil?
Currently, October is the cheapest month in which you can book a flight from San Francisco to Guayaquil (average of $487). Flying from San Francisco to Guayaquil in December is currently the most expensive (average of $1,009). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Guayaquil?
Airfare is typical for this route at the moment.
San Francisco to Guayaquil flights typically cost between $498 and $721 in February.The cheapest round-trip price found within the last 5 days was $584 on American Airlines (Feb 8-Feb 15).
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 10, 2026.
See what other customers who have flown with Copa Airlines,United Airlines, andAmerican Airlines from San Francisco to Guayaquil have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Crew
8.1
Food
6.9
Entertainment
6.9
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
San Francisco and Guayaquil flights
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Top 5 airlines flying from San Francisco to Guayaquil
Discover the top 5 airlines that operate flights from San Francisco to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$203 | Average$577 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$289 | Average$675 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$486 | Average$712 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$550 | Average$690 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$570 | Average$744 | FlexibilityNo cancel fee | On-time71% |