$248+ Cheap flights from San Diego (SAN) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — GYE
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Guayaquil
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One-way
Cheapest flights from San Diego to GuayaquilExplore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:22 pm -
1 stop15h 23m
Wed 10/283:50 pm -
1 stop20h 38m
Deal found 9/6![Multiple Airlines logo]()
$494
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:22 pm -
1 stop18h 18m
Tue 10/273:50 pm -
1 stop20h 38m
Deal found 9/6![Multiple Airlines logo]()
$525
This Trip.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop25h 40m
Thu 10/228:00 pm -
1 stop25h 12m
Deal found 9/7![Multiple Airlines logo]()
$543
This Justfly.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:45 pm -
1 stop35h 00m
Wed 12/93:50 pm -
1 stop24h 08m
Deal found 9/7![Multiple Airlines logo]()
$544
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:24 am -
1 stop19h 21m
Thu 10/158:00 pm -
1 stop20h 35m
Deal found 9/7![Multiple Airlines logo]()
$589
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:22 pm -
2 stops22h 13m
Tue 11/37:35 pm -
2 stops20h 19m
Deal found 9/7![Multiple Airlines logo]()
$598
This oojo deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
1 stop25h 40m
Thu 10/224:05 pm -
1 stop29h 07m
Deal found 9/7![Multiple Airlines logo]()
$603
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/303:40 pm -
1 stop16h 05m
Mon 12/78:00 pm -
1 stop19h 58m
Deal found 9/7![Multiple Airlines logo]()
$608
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:23 am -
1 stop22h 17m
Wed 10/216:50 pm -
2 stops26h 22m
Deal found 9/7![Multiple Airlines logo]()
$619
Best flights from San Diego to GuayaquilDiscover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2410:44 am -
1 stop18h 16m
Wed 3/103:50 pm -
1 stop20h 43m
Deal found 9/6![Multiple Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:15 am -
2 stops13h 24m
Thu 10/222:29 pm -
2 stops20h 38m
Deal found 9/7![American Airlines logo]()
$861
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:00 am -
2 stops13h 37m
Thu 10/2212:18 pm -
2 stops31h 28m
Deal found 9/9![United Airlines logo]()
$869
This Expedia deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:00 am -
1 stop22h 00m
Sun 11/297:35 pm -
2 stops43h 22m
Deal found 9/6![Multiple Airlines logo]()
$667
This oojo deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop25h 40m
Thu 10/228:00 pm -
1 stop25h 12m
Deal found 9/10![Multiple Airlines logo]()
$803
Last-minute flights from San Diego to GuayaquilDiscover last-minute flight deals from San Diego to Guayaquil. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Guayaquil. Data last updated September 10, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
1 stop25h 40m
Thu 10/224:05 pm -
1 stop29h 07m
Deal found 9/7![Multiple Airlines logo]()
$603
This Expedia deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:23 am -
1 stop22h 17m
Wed 10/216:50 pm -
2 stops26h 22m
Deal found 9/7![Multiple Airlines logo]()
$619
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:22 pm -
1 stop18h 18m
Mon 10/263:30 am -
2 stops18h 55m
Deal found 9/6![Multiple Airlines logo]()
$525
This Booking.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:22 pm -
2 stops22h 13m
Tue 11/37:35 pm -
2 stops20h 19m
Deal found 9/7![Multiple Airlines logo]()
$598
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:24 am -
1 stop19h 21m
Thu 10/158:00 pm -
1 stop20h 35m
Deal found 9/7![Multiple Airlines logo]()
$589
This Trip.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop25h 40m
Thu 10/228:00 pm -
1 stop25h 12m
Deal found 9/7![Multiple Airlines logo]()
$543
This Avianca deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:22 pm -
1 stop15h 23m
Wed 10/283:50 pm -
1 stop20h 38m
Deal found 9/6![Multiple Airlines logo]()
$494
One-way flights from San Diego to GuayaquilSearch for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Avianca deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:58 pm -
1 stop15h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$248
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:30 pm -
2 stops33h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:18 pm -
2 stops21h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$458
Find flight deals from San Diego to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $494 (Avianca) |
One-way from | $248 (Avianca) |
Popular in | July |
Cheapest in | January |
Average price | $724 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from San Diego to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Wed 12/2
1:58 pm-8:00 am
1 stop15h 02m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$248
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Sun 9/27
9:30 pm-8:55 am
2 stops33h 25m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Wed 12/2
1:05 pm-2:31 pm
2 stops22h 26m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$458
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Wed 2/24
10:44 am-8:00 am
1 stop18h 16m
Guayaquil Jose Joaquin de Olmedo
Wed 3/10
3:50 pm-9:33 am
1 stop20h 43m
$494
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Tue 11/24
7:00 am-8:00 am
1 stop22h 00m
Guayaquil Jose Joaquin de Olmedo
Sun 11/29
7:35 pm-11:57 am
2 stops43h 22m
$667
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Tue 10/13
7:00 am-10:40 am
1 stop25h 40m
Guayaquil Jose Joaquin de Olmedo
Thu 10/22
8:00 pm-7:12 pm
1 stop25h 12m
$803
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Tue 10/13
7:15 am-10:39 pm
2 stops13h 24m
Guayaquil Jose Joaquin de Olmedo
Thu 10/22
2:29 pm-9:07 am
2 stops20h 38m
$861
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Mon 10/19
8:00 am-11:37 pm
2 stops13h 37m
Guayaquil Jose Joaquin de Olmedo
Thu 10/22
12:18 pm-5:46 pm
2 stops31h 28m
$869
Sorted by cheapest first
Compare providers for flights from San Diego to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Guayaquil in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Diego with our price prediction graph.
SAN-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated September 10, 2026.
Read through reviews of airlines operating flights from San Diego to Guayaquil, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Food
6.9
Boarding
7.8
Entertainment
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Overall
7.6
Food
6.9
Boarding
7.8
Entertainment
6.9
Crew
8.1
Comfort
7.4
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Diego to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Guayaquil by cabin class
Find flights from San Diego to Guayaquil, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
San Diego and Guayaquil flights
Browse other San Diego and Guayaquil flight options. Last updated on September 10, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from San Diego to Guayaquil
Discover the top airline that operate flights from San Diego to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$495 | Average$714 | FlexibilityNo cancel fee | On-time70% |