$245+ Cheap flights from San Diego (SAN) to Guayaquil (GYE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — GYE
Nov 6 — Nov 131
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Guayaquil with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Guayaquil
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to GuayaquilExplore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
Explore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:40 am -
1 stop20h 05m
Mon 11/93:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$506
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:40 am -
1 stop17h 20m
Mon 11/163:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$537
This Justfly.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am -
1 stop22h 00m
Sun 11/223:50 pm -
1 stop24h 02m
Deal found 10/5![Multiple Airlines logo]()
$547
This Avianca deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
1 stop19h 12m
Wed 11/253:30 am -
2 stops19h 14m
Deal found 10/5![Multiple Airlines logo]()
$567
This Expedia deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:22 pm -
2 stops26h 23m
Mon 11/93:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$576
This Travelocity deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:40 pm -
2 stops23h 55m
Sun 11/17:35 pm -
2 stops17h 53m
Deal found 10/5![Multiple Airlines logo]()
$588
This Ovago deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:22 pm -
1 stop15h 23m
Sun 11/13:50 pm -
1 stop23h 54m
Deal found 10/3![Multiple Airlines logo]()
$595
This Expedia deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop25h 40m
Sun 10/114:05 pm -
1 stop19h 09m
Deal found 10/5![Multiple Airlines logo]()
$625
Best flights from San Diego to GuayaquilDiscover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
Discover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
This Avianca deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2112:12 pm -
2 stops17h 53m
Fri 1/298:00 pm -
1 stop19h 58m
Deal found 10/7![Multiple Airlines logo]()
$591
This Copa Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:30 pm -
1 stop23h 10m
Sat 11/148:25 am -
1 stop11h 50m
Deal found 10/6![Copa Airlines logo]()
$685
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:58 pm -
1 stop13h 31m
Sat 11/76:00 am -
1 stop20h 38m
Deal found 10/5![American Airlines logo]()
$811
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:46 pm -
2 stops28h 51m
Thu 10/2212:18 pm -
2 stops31h 28m
Deal found 10/3![United Airlines logo]()
$955
This Orbitz deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:30 pm -
1 stop32h 15m
Sun 11/17:35 pm -
2 stops17h 53m
Deal found 10/3![Multiple Airlines logo]()
$684
This Ovago deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/238:00 am -
2 stops12h 41m
Sat 1/3012:22 pm -
2 stops30h 47m
Deal found 10/3![Copa Airlines logo]()
$1,003
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:33 pm -
2 stops22h 15m
Sat 1/303:48 pm -
1 stop22h 23m
Deal found 10/6![American Airlines logo]()
$1,082
Last-minute flights from San Diego to GuayaquilDiscover last-minute flight deals from San Diego to Guayaquil. Data last updated October 7, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Guayaquil. Data last updated October 7, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am -
1 stop25h 40m
Sun 10/114:05 pm -
1 stop19h 09m
Deal found 10/5![Multiple Airlines logo]()
$625
This Ovago deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:22 pm -
1 stop15h 23m
Sun 11/13:50 pm -
1 stop23h 54m
Deal found 10/3![Multiple Airlines logo]()
$595
This Travelocity deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:40 pm -
2 stops23h 55m
Sun 11/17:35 pm -
2 stops17h 53m
Deal found 10/5![Multiple Airlines logo]()
$588
This Expedia deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:22 pm -
2 stops26h 23m
Mon 11/93:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$576
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:40 am -
1 stop20h 05m
Mon 11/93:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$506
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:40 am -
1 stop17h 20m
Mon 11/163:50 pm -
1 stop21h 45m
Deal found 10/6![Multiple Airlines logo]()
$537
This Justfly.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am -
1 stop22h 00m
Sun 11/223:50 pm -
1 stop24h 02m
Deal found 10/5![Multiple Airlines logo]()
$547
This Avianca deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:33 pm -
1 stop19h 12m
Wed 11/253:30 am -
2 stops19h 14m
Deal found 10/5![Multiple Airlines logo]()
$567
One-way flights from San Diego to GuayaquilSearch for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
Search for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
This eDestinos deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 am -
1 stop22h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$245
This Avianca deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:09 am -
1 stop21h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$289
This Expedia deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:00 am -
3 stops35h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Multiple Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:00 am -
2 stops30h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![United Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:20 pm -
1 stop13h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$597
Find flight deals from San Diego to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 7, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $488 (eDestinos) |
One-way from | $245 (eDestinos) |
Popular in | July |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
Use the filters below to find and compare flights from San Diego to Guayaquil that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Sun 11/8
7:00 am-8:00 am
1 stop22h 00m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$245
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Wed 12/2
12:35 pm-8:00 am
1 stop16h 25m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$289
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Fri 10/16
7:00 am-8:20 pm
3 stops35h 20m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$303
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Wed 12/2
8:00 am-5:36 pm
2 stops30h 36m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$475
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Thu 1/21
12:12 pm-9:05 am
2 stops17h 53m
Guayaquil Jose Joaquin de Olmedo
Fri 1/29
8:00 pm-12:58 pm
1 stop19h 58m
$591
Quickest round-trip
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Fri 10/16
10:20 pm-1:29 pm
1 stop13h 09m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$597
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Mon 10/19
9:30 pm-7:45 am
1 stop32h 15m
Guayaquil Jose Joaquin de Olmedo
Sun 11/1
7:35 pm-10:28 am
2 stops17h 53m
$684
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Fri 10/30
10:30 pm-11:40 pm
1 stop23h 10m
Guayaquil Jose Joaquin de Olmedo
Sat 11/14
8:25 am-5:15 pm
1 stop11h 50m
$685
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Tue 10/27
9:58 pm-1:29 pm
1 stop13h 31m
Guayaquil Jose Joaquin de Olmedo
Sat 11/7
6:00 am-11:38 pm
1 stop20h 38m
$811
San DiegoGuayaquil
SAN San Diego - GYE Guayaquil Jose Joaquin de Olmedo
SANGYE
San Diego
Mon 10/19
4:46 pm-11:37 pm
2 stops28h 51m
Guayaquil Jose Joaquin de Olmedo
Thu 10/22
12:18 pm-5:46 pm
2 stops31h 28m
$955
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from San Diego to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Guayaquil in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Guayaquil flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Guayaquil flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Guayaquil flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Diego with our price prediction graph.
SAN-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated October 7, 2026.
Read through reviews of airlines operating flights from San Diego to Guayaquil, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Crew
8.1
Boarding
7.8
Food
6.9
Overall
7.6
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from San Diego to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
San Diego and Guayaquil flights
Browse other San Diego and Guayaquil flight options. Last updated on October 7, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on October 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from San Diego to Guayaquil
Discover the top airline that operate flights from San Diego to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$495 | Average$675 | FlexibilityNo cancel fee | On-time70% |