$226+ Cheap flights from San Diego (SAN) to Guayaquil (GYE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — GYE
Mar 15 — Mar 221
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Guayaquil
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Best
Last-minute
One-way
Cheapest flights from San Diego to GuayaquilExplore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from San Diego to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This Avianca deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:25 am
SAN
- GYE
1 stop19h 20m
Multiple Airlines
Mon 5/258:00 pm
GYE
- SAN
1 stop15h 46m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:48 pm
SAN
- GYE
1 stop29h 16m
Multiple Airlines
Wed 4/2211:59 pm
GYE
- SAN
1 stop12h 05m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$509
This Trip.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
SAN
- GYE
1 stop25h 45m
Multiple Airlines
Mon 3/308:00 pm
GYE
- SAN
1 stop26h 07m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$517
This Trip.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:58 pm
SAN
- GYE
1 stop34h 47m
Multiple Airlines
Mon 3/308:00 pm
GYE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$564
Best flights from San Diego to GuayaquilDiscover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from San Diego to Guayaquil that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:48 pm
SAN
- GYE
1 stop29h 16m
Multiple Airlines
Wed 4/2211:59 pm
GYE
- SAN
1 stop12h 05m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$509
This Copa Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:18 pm
SAN
- GYE
1 stop18h 13m
Copa Airlines
Wed 4/226:00 am
GYE
- SAN
1 stop14h 30m
Copa Airlines
Deal found 2/11![Copa Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:20 pm
SAN
- GYE
2 stops16h 11m
American Airlines
Wed 4/226:05 am
GYE
- SAN
1 stop18h 23m
American Airlines
Deal found 2/11![American Airlines logo]()
$591
This Orbitz deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:00 am
SAN
- GYE
2 stops23h 55m
Multiple Airlines
Mon 5/258:00 pm
GYE
- SAN
1 stop15h 46m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$537
This Orbitz deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/213:48 pm
SAN
- GYE
2 stops39h 27m
Multiple Airlines
Mon 3/3010:05 am
GYE
- SAN
2 stops27h 33m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$569
This Travelocity deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:02 pm
SAN
- GYE
2 stops23h 33m
Multiple Airlines
Mon 3/303:45 pm
GYE
- SAN
2 stops21h 53m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$577
This Orbitz deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
SAN
- GYE
1 stop25h 45m
Multiple Airlines
Sun 3/296:50 pm
GYE
- SAN
2 stops42h 56m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$590
This Travelocity deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:02 pm
SAN
- GYE
2 stops23h 33m
Multiple Airlines
Thu 4/24:05 am
GYE
- SAN
2 stops18h 40m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$593
Last-minute flights from San Diego to GuayaquilDiscover last-minute flight deals from San Diego to Guayaquil. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Guayaquil. Data last updated February 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:00 am
SAN
- GYE
2 stops30h 35m
United Airlines
Fri 2/2712:20 pm
GYE
- SAN
2 stops28h 27m
United Airlines
Deal found 2/9![United Airlines logo]()
$671
This Trip.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
SAN
- GYE
1 stop25h 45m
Multiple Airlines
Mon 3/308:00 pm
GYE
- SAN
1 stop26h 07m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$517
This Orbitz deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:00 am
SAN
- GYE
1 stop25h 45m
Multiple Airlines
Sun 3/296:50 pm
GYE
- SAN
2 stops42h 56m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$590
This Trip.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:58 pm
SAN
- GYE
1 stop34h 47m
Multiple Airlines
Mon 3/308:00 pm
GYE
- SAN
1 stop18h 52m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$564
This Travelocity deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:02 pm
SAN
- GYE
2 stops23h 33m
Multiple Airlines
Thu 4/24:05 am
GYE
- SAN
2 stops18h 40m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$593
One-way flights from San Diego to GuayaquilSearch for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from San Diego to Guayaquil. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 am
SAN
- GYE
3 stops39h 50m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$226
This eDestinos deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:00 am
SAN
- GYE
1 stop24h 40m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$229
Find flight deals from San Diego to Guayaquil
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $485 (Avianca) |
One-way from | $226 (Kiwi.com) |
Popular in | May |
Cheapest in | January |
Average price | $657 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from San Diego to Guayaquil that are best for you.
Fly from
San Diego
Fly to
Guayaquil
Route
Depart
Return
Price
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Sat 4/11
3:48 pm-11:04 pm
1 stop29h 16m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
11:59 pm-10:04 am
1 stop12h 05m
$509
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Mon 5/11
7:00 am-8:55 am
2 stops23h 55m
Guayaquil Jose Joaquin de Olmedo
Mon 5/25
8:00 pm-9:46 am
1 stop15h 46m
$537
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Sat 3/21
3:48 pm-9:15 am
2 stops39h 27m
Guayaquil Jose Joaquin de Olmedo
Mon 3/30
10:05 am-11:38 am
2 stops27h 33m
$569
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Fri 3/20
10:02 pm-11:35 pm
2 stops23h 33m
Guayaquil Jose Joaquin de Olmedo
Mon 3/30
3:45 pm-11:38 am
2 stops21h 53m
$577
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Fri 4/10
9:18 pm-5:31 pm
1 stop18h 13m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
6:00 am-6:30 pm
1 stop14h 30m
$584
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Fri 3/20
7:00 am-10:45 am
1 stop25h 45m
Guayaquil Jose Joaquin de Olmedo
Sun 3/29
6:50 pm-11:46 am
2 stops42h 56m
$590
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Sat 4/11
7:20 pm-1:31 pm
2 stops16h 11m
Guayaquil Jose Joaquin de Olmedo
Wed 4/22
6:05 am-10:28 pm
1 stop18h 23m
$591
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Sun 3/22
10:02 pm-11:35 pm
2 stops23h 33m
Guayaquil Jose Joaquin de Olmedo
Thu 4/2
4:05 am-8:45 pm
2 stops18h 40m
$593
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Sun 3/29
6:55 am-12:45 am
3 stops39h 50m
$226
San DiegoGuayaquil
SAN - GYE
SANGYE
San Diego
Fri 5/29
8:00 am-10:40 am
1 stop24h 40m
$229
Compare providers for flights from San Diego to Guayaquil
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Guayaquil in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Guayaquil flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Guayaquil
Have a flexible travel schedule? Discover the best time to fly to Guayaquil from San Diego with our price prediction graph.
SAN-GYE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Guayaquil
Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 13, 2026.
Read through reviews of airlines operating flights from San Diego to Guayaquil, such as Copa Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Comfort
7.4
Overall
7.5
Boarding
7.8
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Crew
8.1
Comfort
7.4
Overall
7.5
Boarding
7.8
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Crew
8.1
Comfort
7.4
Overall
7.5
Boarding
7.8
Entertainment
6.8
Food
6.8
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from San Diego to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Guayaquil by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Guayaquil by cabin class
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Other flights to Guayaquil
Explore flights to Guayaquil departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 13, 2026.
San Diego and Guayaquil flights
Browse other San Diego and Guayaquil flight options. Last updated on February 13, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on February 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Diego to Guayaquil
Discover the top 2 airlines that operate flights from San Diego to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$469 | Average$614 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$546 | Average$751 | FlexibilityNo cancel fee | On-time69% |