$345+ Cheap flights from Guayaquil (GYE) to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SAN
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Diego
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One-way
Cheapest flights from Guayaquil to San DiegoExplore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:25 am -
1 stop11h 50m
Mon 11/3010:30 pm -
1 stop19h 27m
Deal found 10/8![Copa Airlines logo]()
$758
This Mytrip deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:50 pm -
2 stops21h 45m
Wed 11/410:00 pm -
1 stop33h 45m
Deal found 10/4![Multiple Airlines logo]()
$776
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/293:30 pm -
1 stop22h 55m
Tue 1/1210:40 pm -
1 stop21h 57m
Deal found 10/5![American Airlines logo]()
$802
This Travelocity deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:35 pm -
2 stops43h 09m
Tue 12/812:35 pm -
2 stops32h 00m
Deal found 10/6![Multiple Airlines logo]()
$807
This Avianca deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:05 pm -
1 stop19h 04m
Sat 10/242:07 pm -
2 stops16h 53m
Deal found 10/7![Multiple Airlines logo]()
$818
This Travelocity deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:50 pm -
1 stop24h 02m
Wed 12/99:40 pm -
1 stop34h 05m
Deal found 10/6![Multiple Airlines logo]()
$820
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop20h 49m
Mon 11/3012:55 pm -
1 stop22h 40m
Deal found 10/7![American Airlines logo]()
$825
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop18h 43m
Sat 10/3112:56 pm -
1 stop23h 38m
Deal found 10/5![American Airlines logo]()
$831
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop18h 43m
Sat 10/249:58 pm -
1 stop13h 31m
Deal found 10/5![American Airlines logo]()
$838
Best flights from Guayaquil to San DiegoDiscover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:30 pm -
1 stop26h 00m
Wed 11/410:30 pm -
1 stop22h 10m
Deal found 10/4![Copa Airlines logo]()
$758
This Booking.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/153:30 am -
2 stops20h 55m
Tue 2/231:58 pm -
1 stop15h 02m
Deal found 10/6![Multiple Airlines logo]()
$801
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:35 pm -
2 stops19h 58m
Mon 11/3012:55 pm -
1 stop22h 40m
Deal found 10/7![American Airlines logo]()
$830
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:25 pm -
2 stops27h 59m
Mon 11/305:00 pm -
2 stops24h 57m
Deal found 10/6![United Airlines logo]()
$874
This Copa Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:25 am -
1 stop11h 50m
Mon 11/3010:30 pm -
1 stop19h 27m
Deal found 10/8![Copa Airlines logo]()
$758
Last-minute flights from Guayaquil to San DiegoDiscover last-minute flight deals from Guayaquil to San Diego. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Diego. Data last updated October 8, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop18h 43m
Sat 10/249:58 pm -
1 stop13h 31m
Deal found 10/5![American Airlines logo]()
$838
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop18h 43m
Sat 10/3112:56 pm -
1 stop23h 38m
Deal found 10/5![American Airlines logo]()
$831
This Travelocity deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:55 pm -
2 stops38h 14m
Sat 10/317:00 am -
2 stops30h 10m
Deal found 10/5![Multiple Airlines logo]()
$841
This Mytrip deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:50 pm -
2 stops21h 45m
Wed 11/410:00 pm -
1 stop33h 45m
Deal found 10/4![Multiple Airlines logo]()
$776
This Avianca deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:05 pm -
1 stop19h 04m
Sat 10/242:07 pm -
2 stops16h 53m
Deal found 10/7![Multiple Airlines logo]()
$818
This Copa Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:25 am -
1 stop11h 50m
Mon 11/3010:30 pm -
1 stop19h 27m
Deal found 10/8![Copa Airlines logo]()
$758
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop20h 49m
Mon 11/3012:55 pm -
1 stop22h 40m
Deal found 10/7![American Airlines logo]()
$825
This Travelocity deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:50 pm -
1 stop24h 02m
Wed 12/99:40 pm -
1 stop34h 05m
Deal found 10/6![Multiple Airlines logo]()
$820
This Travelocity deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:35 pm -
2 stops43h 09m
Tue 12/812:35 pm -
2 stops32h 00m
Deal found 10/6![Multiple Airlines logo]()
$807
One-way flights from Guayaquil to San DiegoSearch for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:22 am -
3 stops31h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:54 am -
3 stops40h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:38 pm -
3 stops24h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$372
This eDestinos deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:00 pm -
1 stop26h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Multiple Airlines logo]()
$421
This Avianca deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:35 pm -
2 stops18h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$449
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:47 pm -
2 stops34h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![United Airlines logo]()
$467
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:25 am -
1 stop11h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Copa Airlines logo]()
$528
Find flight deals from Guayaquil to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $733 (eDestinos) |
One-way from | $345 (Kiwi.com) |
Popular in | July |
Cheapest in | March |
Average price | $604 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 11/6
4:22 am-8:37 am
3 stops31h 15m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$345
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/16
6:38 pm-3:58 pm
3 stops24h 20m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$372
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
8:00 pm-7:23 pm
1 stop26h 23m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$421
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Wed 11/25
7:35 pm-11:18 am
2 stops18h 43m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$449
Quickest round-trip
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 11/15
8:00 pm-10:35 am
1 stop17h 35m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$450
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
3:30 am-7:23 pm
2 stops18h 53m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$450
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
2:47 pm-9:59 pm
2 stops34h 12m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$467
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 10/20
6:30 pm-6:30 pm
1 stop26h 00m
San Diego
Wed 11/4
10:30 pm-11:40 pm
1 stop22h 10m
$758
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
8:25 am-5:15 pm
1 stop11h 50m
San Diego
Mon 11/30
10:30 pm-8:57 pm
1 stop19h 27m
$758
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 2/15
3:30 am-9:25 pm
2 stops20h 55m
San Diego
Tue 2/23
1:58 pm-8:00 am
1 stop15h 02m
$801
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Diego in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Guayaquil with our price prediction graph.
GYE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Diego
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 8, 2026.
Get a feel of what it's like to fly with Copa Airlines from Guayaquil to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.6
Boarding
7.8
Comfort
7.4
Crew
8.1
Entertainment
6.9
Food
6.9
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Overall
7.6
Boarding
7.8
Comfort
7.4
Crew
8.1
Entertainment
6.9
Food
6.9
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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San Ysidro
Poway
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La Mesa
Julian
Santee
Lemon Grove
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Guayaquil and San Diego flights
Browse other Guayaquil and San Diego flight options. Last updated on October 8, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on October 8, 2026.
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Top airline flying from Guayaquil to San Diego
Discover the top airline that operate flights from Guayaquil to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$556 | Average$610 | FlexibilityNo cancel fee | On-time70% |