$338+ Cheap flights from Guayaquil (GYE) to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SAN
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Diego
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One-way
Cheapest flights from Guayaquil to San DiegoExplore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:54 pm -
1 stop20h 24m
Wed 1/201:53 pm -
1 stop15h 07m
Deal found 9/15![Multiple Airlines logo]()
$619
This Priceline deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:54 pm -
1 stop19h 41m
Thu 11/1912:30 pm -
1 stop19h 15m
Deal found 9/18![Multiple Airlines logo]()
$654
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:50 pm -
2 stops28h 44m
Mon 10/192:22 pm -
1 stop15h 23m
Deal found 9/15![Multiple Airlines logo]()
$694
This Travelocity deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:54 pm -
1 stop20h 24m
Mon 11/97:00 am -
1 stop22h 00m
Deal found 9/18![Multiple Airlines logo]()
$728
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:10 am -
2 stops26h 30m
Sat 10/317:00 am -
1 stop23h 00m
Deal found 9/15![Multiple Airlines logo]()
$733
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:45 pm -
2 stops24h 50m
Sun 10/187:00 am -
1 stop22h 45m
Deal found 9/15![Multiple Airlines logo]()
$748
Best flights from Guayaquil to San DiegoDiscover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:25 am -
1 stop11h 50m
Sat 11/1410:30 pm -
1 stop12h 12m
Deal found 9/16![Copa Airlines logo]()
$760
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:25 pm -
2 stops27h 59m
Mon 11/305:00 pm -
2 stops24h 57m
Deal found 9/18![United Airlines logo]()
$850
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:01 am -
1 stop14h 29m
Thu 10/2910:30 pm -
1 stop10h 45m
Deal found 9/15![Copa Airlines logo]()
$780
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:33 pm -
2 stops56h 51m
Mon 10/194:46 pm -
2 stops28h 51m
Deal found 9/15![United Airlines logo]()
$850
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:33 pm -
2 stops29h 13m
Mon 10/265:00 pm -
2 stops22h 32m
Deal found 9/17![United Airlines logo]()
$859
Last-minute flights from Guayaquil to San DiegoDiscover last-minute flight deals from Guayaquil to San Diego. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Diego. Data last updated September 18, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:01 am -
1 stop14h 29m
Thu 10/2910:30 pm -
1 stop10h 45m
Deal found 9/15![Copa Airlines logo]()
$780
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:24 am -
1 stop12h 06m
Thu 10/299:27 pm -
2 stops38h 13m
Deal found 9/15![Multiple Airlines logo]()
$789
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:50 pm -
2 stops28h 44m
Mon 10/192:22 pm -
1 stop15h 23m
Deal found 9/15![Multiple Airlines logo]()
$694
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:45 pm -
2 stops24h 50m
Sun 10/187:00 am -
1 stop22h 45m
Deal found 9/15![Multiple Airlines logo]()
$748
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:29 pm -
1 stop23h 27m
Mon 10/1910:20 pm -
1 stop22h 19m
Deal found 9/15![American Airlines logo]()
$768
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:10 am -
2 stops26h 30m
Sat 10/317:00 am -
1 stop23h 00m
Deal found 9/15![Multiple Airlines logo]()
$733
This Travelocity deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:54 pm -
1 stop20h 24m
Mon 11/97:00 am -
1 stop22h 00m
Deal found 9/18![Multiple Airlines logo]()
$728
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:50 pm -
1 stop21h 28m
Fri 11/62:08 pm -
2 stops15h 52m
Deal found 9/15![Multiple Airlines logo]()
$763
One-way flights from Guayaquil to San DiegoSearch for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 pm -
1 stop20h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![JetBlue logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:01 am -
3 stops35h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/153:30 am -
2 stops20h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$394
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:14 am -
1 stop16h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Copa Airlines logo]()
$408
This eDestinos deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:00 pm -
1 stop26h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:29 pm -
1 stop23h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$423
Find flight deals from Guayaquil to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $619 (Priceline) |
One-way from | $338 (Cheapflightsfares) |
Popular in | July |
Cheapest in | March |
Average price | $696 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
6:00 pm-11:18 am
1 stop20h 18m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$338
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
6:01 am-3:58 pm
3 stops35h 57m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$388
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 2/15
3:30 am-9:25 pm
2 stops20h 55m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$394
Quickest round-trip
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 10/16
4:14 am-6:30 pm
1 stop16h 16m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$408
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 2/16
6:33 pm-5:28 pm
1 stop25h 55m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$408
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
8:00 pm-7:23 pm
1 stop26h 23m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
3:35 pm-8:33 am
2 stops19h 58m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$438
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 11/1
8:25 am-5:15 pm
1 stop11h 50m
San Diego
Sat 11/14
10:30 pm-1:42 pm
1 stop12h 12m
$760
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 10/11
6:01 am-6:30 pm
1 stop14h 29m
San Diego
Thu 10/29
10:30 pm-11:15 am
1 stop10h 45m
$780
GuayaquilSan Diego
GYE Guayaquil Jose Joaquin de Olmedo - SAN San Diego
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
12:25 pm-1:24 pm
2 stops27h 59m
San Diego
Mon 11/30
5:00 pm-8:57 pm
2 stops24h 57m
$850
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Guayaquil with our price prediction graph.
GYE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 18, 2026.
Get a feel of what it's like to fly with Copa Airlines from Guayaquil to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Entertainment
6.9
Crew
8.1
Food
6.9
Boarding
7.8
Overall
7.6
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Comfort
7.4
Entertainment
6.9
Crew
8.1
Food
6.9
Boarding
7.8
Overall
7.6
Reviews
1 / 20
4.0
OkayPaul,Jun 2025
PTY - MIA
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
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Coronado
San Ysidro
Poway
La Mesa
Santee
Julian
Lemon Grove
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Guayaquil and San Diego flights
Browse other Guayaquil and San Diego flight options. Last updated on September 18, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
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Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Top airline flying from Guayaquil to San Diego
Discover the top airline that operate flights from Guayaquil to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$556 | Average$603 | FlexibilityNo cancel fee | On-time70% |