$327+ Cheap flights from Guayaquil (GYE) to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SAN
Jul 20 — Jul 271
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Diego
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Cheapest flights from Guayaquil to San DiegoExplore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
Explore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.
This eDestinos deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:00 pm
GYE
- SAN
1 stop20h 50m
Multiple Airlines
Mon 9/287:00 am
SAN
- GYE
1 stop25h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$564
This eDestinos deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:40 pm
GYE
- SAN
1 stop26h 19m
Multiple Airlines
Mon 11/309:56 pm
SAN
- GYE
1 stop33h 49m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$585
This eDestinos deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/63:30 am
GYE
- SAN
2 stops19h 01m
Multiple Airlines
Mon 9/212:20 pm
SAN
- GYE
1 stop15h 25m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$593
This Travelocity deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:50 pm
GYE
- SAN
2 stops40h 27m
Multiple Airlines
Sat 9/267:00 am
SAN
- GYE
1 stop22h 45m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$635
This Mytrip deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:00 pm
GYE
- SAN
1 stop25h 35m
Multiple Airlines
Mon 10/127:00 am
SAN
- GYE
2 stops23h 55m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$639
This oojo deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:00 pm
GYE
- SAN
1 stop20h 27m
Multiple Airlines
Wed 8/1211:50 am
SAN
- GYE
2 stops24h 45m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$642
Best flights from Guayaquil to San DiegoDiscover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
Discover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 20, 2026.
This eDestinos deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:30 am
GYE
- SAN
2 stops19h 01m
Multiple Airlines
Mon 9/282:20 pm
SAN
- GYE
2 stops17h 55m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$629
This Copa Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:13 am
GYE
- SAN
1 stop16h 17m
Copa Airlines
Mon 9/2110:00 pm
SAN
- GYE
1 stop13h 34m
Copa Airlines
Deal found 6/15![Copa Airlines logo]()
$664
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:36 pm
GYE
- SAN
2 stops29h 05m
United Airlines
Wed 7/296:15 am
SAN
- GYE
2 stops15h 23m
United Airlines
Deal found 6/18![United Airlines logo]()
$775
This Avianca deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 pm
GYE
- SAN
1 stop15h 47m
Multiple Airlines
Thu 9/34:14 pm
SAN
- GYE
2 stops14h 41m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:21 pm
GYE
- SAN
2 stops27h 00m
United Airlines
Wed 8/123:04 pm
SAN
- GYE
2 stops30h 34m
United Airlines
Deal found 6/18![United Airlines logo]()
$799
This KAYAK deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:21 pm
GYE
- SAN
2 stops24h 30m
Copa Airlines
Wed 7/296:15 am
SAN
- GYE
2 stops15h 23m
Copa Airlines
Deal found 6/15![Copa Airlines logo]()
$799
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:36 pm
GYE
- SAN
2 stops29h 05m
United Airlines
Tue 7/215:15 pm
SAN
- GYE
2 stops22h 16m
United Airlines
Deal found 6/15![United Airlines logo]()
$805
Last-minute flights from Guayaquil to San DiegoDiscover last-minute flight deals from Guayaquil to San Diego. Data last updated June 20, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Diego. Data last updated June 20, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/131:40 pm
GYE
- SAN
2 stops32h 28m
Multiple Airlines
Wed 7/299:06 pm
SAN
- GYE
2 stops24h 24m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$690
This Avianca deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/138:00 pm
GYE
- SAN
1 stop16h 34m
Multiple Airlines
Wed 8/1911:50 am
SAN
- GYE
1 stop17h 55m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$694
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:00 am
GYE
- SAN
1 stop18h 38m
American Airlines
Wed 7/297:15 am
SAN
- GYE
2 stops13h 22m
American Airlines
Deal found 6/19![American Airlines logo]()
$765
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/132:36 pm
GYE
- SAN
2 stops29h 05m
United Airlines
Wed 7/296:15 am
SAN
- GYE
2 stops15h 23m
United Airlines
Deal found 6/19![United Airlines logo]()
$775
This oojo deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:00 pm
GYE
- SAN
1 stop20h 27m
Multiple Airlines
Wed 8/1211:50 am
SAN
- GYE
2 stops24h 45m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$642
This Avianca deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/268:00 pm
GYE
- SAN
1 stop16h 34m
Multiple Airlines
Mon 8/102:15 pm
SAN
- GYE
1 stop18h 25m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$718
This oojo deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:05 am
GYE
- SAN
2 stops25h 32m
Multiple Airlines
Fri 8/148:52 pm
SAN
- GYE
2 stops18h 43m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$684
This Copa Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/294:12 am
GYE
- SAN
1 stop16h 18m
Copa Airlines
Fri 8/1410:00 pm
SAN
- GYE
1 stop24h 02m
Copa Airlines
Deal found 6/16![Copa Airlines logo]()
$796
One-way flights from Guayaquil to San DiegoSearch for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
Search for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated June 20, 2026.
This eDestinos deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:05 pm
GYE
- SAN
1 stop23h 49m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am
GYE
- SAN
2 stops20h 56m
American Airlines
Deal found 6/16![American Airlines logo]()
$379
This Expedia deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:50 pm
GYE
- SAN
2 stops45h 37m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:48 am
GYE
- SAN
3 stops28h 20m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:21 pm
GYE
- SAN
2 stops31h 20m
United Airlines
Deal found 6/15![United Airlines logo]()
$407
This Copa Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:27 pm
GYE
- SAN
1 stop26h 03m
Copa Airlines
Deal found 6/15![Copa Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:47 pm
GYE
- SAN
3 stops47h 48m
United Airlines
Deal found 6/19![United Airlines logo]()
$455
Find flight deals from Guayaquil to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $564 (eDestinos) |
One-way from | $327 (eDestinos) |
Popular in | May |
Cheapest in | October |
Average price | $875 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 9/13
3:30 am-8:31 pm
2 stops19h 01m
San Diego
Mon 9/28
2:20 pm-10:15 am
2 stops17h 55m
$629
Quickest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 9/7
4:13 am-6:30 pm
1 stop16h 17m
San Diego
Mon 9/21
10:00 pm-1:34 pm
1 stop13h 34m
$664
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 8/24
8:00 pm-9:47 am
1 stop15h 47m
San Diego
Thu 9/3
4:14 pm-8:55 am
2 stops14h 41m
$691
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 7/13
2:36 pm-5:41 pm
2 stops29h 05m
San Diego
Wed 7/29
6:15 am-11:38 pm
2 stops15h 23m
$775
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 7/14
12:21 pm-1:21 pm
2 stops27h 00m
San Diego
Wed 8/12
3:04 pm-11:38 pm
2 stops30h 34m
$799
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 7/13
12:21 pm-10:51 am
2 stops24h 30m
San Diego
Wed 7/29
6:15 am-11:38 pm
2 stops15h 23m
$799
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Wed 7/1
2:36 pm-5:41 pm
2 stops29h 05m
San Diego
Tue 7/21
5:15 pm-5:31 pm
2 stops22h 16m
$805
Cheapest one-way
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
4:05 pm-12:54 pm
1 stop23h 49m
$327
Quickest one-way
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 11/23
6:00 am-11:56 pm
2 stops20h 56m
$381
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 6/30
6:50 pm-2:27 pm
2 stops45h 37m
$390
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Diego in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Guayaquil with our price prediction graph.
GYE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Diego
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 20, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Guayaquil to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Crew
8.1
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Crew
8.1
Overall
7.6
Boarding
7.8
Food
6.9
Comfort
7.4
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Santee
Julian
Lemon Grove
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Guayaquil and San Diego flights
Browse other Guayaquil and San Diego flight options. Last updated on June 20, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on June 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 20, 2026.
Top 2 airlines flying from Guayaquil to San Diego
Discover the top 2 airlines that operate flights from Guayaquil to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$280 | Average$603 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$337 | Average$496 | FlexibilityNo cancel fee | On-time69% |