HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$164+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Jul 7 — Jul 141
Mon 7/7
Mon 7/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated July 2, 2025.

Round-trip from

$330
(eDestinos)

One-way from

$164
(Copa Airlines)

Popular in

December

Cheapest in

August

Average price

$1,071
From San Diego to South America
Search Deals
One-way flight from San Diego to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($159 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 2, 2025.

This eDestinos deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/293:57 pmSAN - BOG
2 stops19h 08mSpirit Airlines
Tue 8/52:00 pmBOG - SAN
2 stops21h 55mSpirit Airlines
Deal found 6/30$330
This Copa Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/159:03 pmSAN - MDE
1 stop9h 14mCopa Airlines
Fri 8/2210:46 amMDE - SAN
1 stop8h 58mCopa Airlines
Deal found 7/1$369
This Mytrip deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/229:03 pmSAN - BOG
1 stop23h 52mCopa Airlines
Fri 9/56:10 amBOG - SAN
1 stop13h 40mCopa Airlines
Deal found 7/1$372
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/161:17 pmSAN - MDE
2 stops22h 05mSpirit Airlines
Fri 8/2212:49 amMDE - SAN
2 stops24h 48mSpirit Airlines
Deal found 7/1$383
This Mytrip deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/215:13 pmSAN - BOG
3 stops27h 42mMultiple Airlines
Tue 7/292:00 pmBOG - SAN
2 stops21h 55mMultiple Airlines
Deal found 6/29$420
This Copa Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/79:08 pmSAN - LIM
1 stop20h 07mCopa Airlines
Mon 9/227:00 amLIM - SAN
1 stop12h 50mCopa Airlines
Deal found 7/2$452
This Expedia deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/169:50 pmSAN - MDE
1 stop16h 50mMultiple Airlines
Sat 8/235:59 amMDE - SAN
1 stop16h 30mMultiple Airlines
Deal found 7/1$488
This Justfly.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2010:30 pmSAN - BOG
1 stop18h 45mLATAM Airlines
Wed 8/277:00 amBOG - SAN
2 stops17h 54mLATAM Airlines
Deal found 6/30$494
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2010:15 amSAN - BOG
1 stop16h 39mUnited Airlines
Sun 8/2412:14 amBOG - SAN
1 stop19h 45mUnited Airlines
Deal found 6/30$513
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/217:12 amSAN - BOG
1 stop13h 18mAmerican Airlines
Wed 7/2312:25 amBOG - SAN
1 stop16h 05mAmerican Airlines
Deal found 6/30$515
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2010:30 pmSAN - BOG
2 stops16h 05mDelta
Tue 8/267:00 amBOG - SAN
2 stops16h 15mDelta
Deal found 6/30$517
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:20 amSAN - MDE
1 stop8h 45mUnited Airlines
Sun 12/211:15 amMDE - SAN
2 stops18h 55mUnited Airlines
Deal found 7/2$522

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

San Diego

Fly to

South America

Route

Depart

Return

Price

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Tue 7/29

3:57 pm-1:05 pm

2 stops19h 08m

Bogotá El Dorado

Tue 8/5

2:00 pm-9:55 am

2 stops21h 55m

$330

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Fri 8/15

9:03 pm-8:17 am

1 stop9h 14m

Medellín Jose Maria Cordova Intl

Fri 8/22

10:46 am-5:44 pm

1 stop8h 58m

$369

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Fri 8/22

9:03 pm-10:55 pm

1 stop23h 52m

Bogotá El Dorado

Fri 9/5

6:10 am-5:50 pm

1 stop13h 40m

$372

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sat 8/16

1:17 pm-1:22 pm

2 stops22h 05m

Medellín Jose Maria Cordova Intl

Fri 8/22

12:49 am-11:37 pm

2 stops24h 48m

$383

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Mon 7/21

5:13 pm-10:55 pm

3 stops27h 42m

Bogotá El Dorado

Tue 7/29

2:00 pm-9:55 am

2 stops21h 55m

$420

San DiegoLima

SAN - LIM

SANLIM

San Diego

Sun 9/7

9:08 pm-7:15 pm

1 stop20h 07m

Lima J Chavez Intl

Mon 9/22

7:00 am-5:50 pm

1 stop12h 50m

$452

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sat 8/16

9:50 pm-4:40 pm

1 stop16h 50m

Medellín Jose Maria Cordova Intl

Sat 8/23

5:59 am-8:29 pm

1 stop16h 30m

$488

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Wed 8/20

10:30 pm-7:15 pm

1 stop18h 45m

Bogotá El Dorado

Wed 8/27

7:00 am-10:54 pm

2 stops17h 54m

$494

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Wed 8/20

10:15 am-4:54 am

1 stop16h 39m

Bogotá El Dorado

Sun 8/24

12:14 am-5:59 pm

1 stop19h 45m

$513

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Mon 7/21

7:12 am-10:30 pm

1 stop13h 18m

Bogotá El Dorado

Wed 7/23

12:25 am-2:30 pm

1 stop16h 05m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SA?

Find hourly flight availability from San Diego to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 2, 2025.

When flying from San Diego to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 2, 2025.
See what other customers who have flown with Delta, LATAM Airlines, and Copa Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,805 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,465 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Overall

8.0

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are Copa Airlines ($164), Spirit Airlines ($166), and LATAM Airlines ($228).

  • What are the most popular routes from San Diego to South America?

    The most popular route from San Diego to South America is San Diego - Santiago Arturo Merino Benitez. You may also consider San Diego - Buenos Aires Ministro Pistarini or San Diego - Lima J Chavez Intl.

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to South America

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Los Angeles to Seattle flights
Los Angeles to Newark flights
Los Angeles to Haneda flights
Los Angeles to Honolulu flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to San Francisco flights
San Francisco to Los Angeles flights
San Francisco to Las Vegas flights
Ontario to Seattle flights
Los Angeles to O'Hare Intl flights
San Francisco to Newark flights
Los Angeles to Narita flights
San Francisco to Seattle flights
Los Angeles to Las Vegas flights
Los Angeles to LaGuardia flights
Los Angeles to Cancún flights
San Francisco to Santa Ana flights
Los Angeles to Portland flights
Santa Ana to San Francisco flights
Los Angeles to Orlando flights
Los Angeles to Boston flights
Los Angeles to Mexico City flights
Santa Ana to Seattle flights
San Jose to Los Angeles flights
San Francisco to Honolulu flights
Santa Ana to Las Vegas flights
Los Angeles to Miami flights
Los Angeles to San Jose flights
Oakland to Las Vegas flights
San Francisco to LaGuardia flights
San Francisco to Narita flights
San Francisco to O'Hare Intl flights
Burbank to Las Vegas flights
San Jose to Seattle flights
Los Angeles to Manila flights
Los Angeles to Denver flights
Ontario to Honolulu flights
San Francisco to Haneda flights
Los Angeles to Heathrow flights
Ontario to San Francisco flights
Oakland to Seattle flights
Ontario to Dallas/Fort Worth flights
Ontario to John F Kennedy Intl flights
San Francisco to Manila flights
Oakland to Los Angeles flights
Los Angeles to Fort Lauderdale flights
Los Angeles to San Salvador flights
Los Angeles to Hobby flights

Top 6 airlines flying from San Diego to South America

Discover the top 6 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$337Average$687FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$395Average$440FlexibilityNo cancel feeOn-time65%
DeltaCheapest$430Average$1,027FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$433Average$956FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$435Average$909FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$449Average$893FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.