HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$166+ Cheap flights from San Diego (SAN) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Jul 16 — Jul 231
Wed 7/16
Wed 7/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Diego to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Diego to South America

Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated July 11, 2025.

Round-trip from

$332
(FlightHub)

One-way from

$166
(FlightHub)

Popular in

December

Cheapest in

August

Average price

$1,071
From San Diego to South America
Search Deals
One-way flight from San Diego to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($159 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from San Diego to South America

Cheapest flights from San Diego to South America
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

This FlightHub deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/57:00 pmSAN - BOG
2 stops15h 00mSpirit Airlines
Mon 8/112:00 pmBOG - SAN
2 stops21h 55mSpirit Airlines
Deal found 7/10$332
This Copa Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:12 pmSAN - BOG
1 stop14h 17mCopa Airlines
Fri 10/249:45 amBOG - SAN
1 stop10h 12mCopa Airlines
Deal found 7/10$373
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/249:03 pmSAN - MDE
1 stop17h 57mCopa Airlines
Sun 8/319:15 amMDE - SAN
1 stop10h 29mCopa Airlines
Deal found 7/9$386
This FlightHub deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/45:13 pmSAN - MDE
2 stops17h 51mSpirit Airlines
Fri 8/2212:49 amMDE - SAN
2 stops24h 48mSpirit Airlines
Deal found 7/10$396
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/139:00 amSAN - MDE
1 stop26h 00mMultiple Airlines
Tue 10/72:00 pmMDE - SAN
1 stop30h 46mMultiple Airlines
Deal found 7/10$397
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:48 amSAN - BOG
1 stop25h 09mMultiple Airlines
Wed 10/2212:52 pmBOG - SAN
1 stop31h 54mMultiple Airlines
Deal found 7/10$431
This Copa Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/49:03 pmSAN - GRU
1 stop23h 27mCopa Airlines
Sat 8/303:10 amGRU - SAN
1 stop18h 34mCopa Airlines
Deal found 7/10$447
This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/79:08 pmSAN - LIM
1 stop20h 07mCopa Airlines
Mon 9/227:00 amLIM - SAN
1 stop12h 50mCopa Airlines
Deal found 7/8$452
This Copa Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/108:10 pmSAN - UIO
1 stop18h 22mCopa Airlines
Fri 11/216:04 amUIO - SAN
1 stop13h 59mCopa Airlines
Deal found 7/10$460
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/179:03 pmSAN - SCL
1 stop23h 05mCopa Airlines
Tue 9/211:29 amSCL - SAN
1 stop33h 21mCopa Airlines
Deal found 7/10$469
This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/39:08 pmSAN - GIG
1 stop23h 17mCopa Airlines
Sun 9/211:27 amGIG - SAN
1 stop20h 23mCopa Airlines
Deal found 7/8$493
This Justfly.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1512:50 pmSAN - BOG
2 stops20h 05mLATAM Airlines
Fri 10/2410:15 amBOG - SAN
2 stops14h 44mLATAM Airlines
Deal found 7/10$494

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
Use the filters below to find and compare flights from San Diego to South America that are best for you.

Fly from

San Diego

Fly to

South America

Route

Depart

Return

Price

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Tue 8/5

7:00 pm-12:00 pm

2 stops15h 00m

Bogotá El Dorado

Mon 8/11

2:00 pm-9:55 am

2 stops21h 55m

$332

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Mon 10/13

9:12 pm-1:29 pm

1 stop14h 17m

Bogotá El Dorado

Fri 10/24

9:45 am-5:57 pm

1 stop10h 12m

$373

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sun 8/24

9:03 pm-5:00 pm

1 stop17h 57m

Medellín Jose Maria Cordova Intl

Sun 8/31

9:15 am-5:44 pm

1 stop10h 29m

$386

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Mon 8/4

5:13 pm-1:04 pm

2 stops17h 51m

Medellín Jose Maria Cordova Intl

Fri 8/22

12:49 am-11:37 pm

2 stops24h 48m

$396

San DiegoMedellín

SAN - MDE

SANMDE

San Diego

Sat 9/13

9:00 am-1:00 pm

1 stop26h 00m

Medellín Jose Maria Cordova Intl

Tue 10/7

2:00 pm-6:46 pm

1 stop30h 46m

$397

San DiegoBogotá

SAN - BOG

SANBOG

San Diego

Wed 10/15

8:48 am-11:57 am

1 stop25h 09m

Bogotá El Dorado

Wed 10/22

12:52 pm-6:46 pm

1 stop31h 54m

$431

San DiegoSao Paulo

SAN - GRU

SANGRU

San Diego

Mon 8/4

9:03 pm-12:30 am

1 stop23h 27m

Sao Paulo Guarulhos Intl

Sat 8/30

3:10 am-5:44 pm

1 stop18h 34m

$447

San DiegoLima

SAN - LIM

SANLIM

San Diego

Sun 9/7

9:08 pm-7:15 pm

1 stop20h 07m

Lima J Chavez Intl

Mon 9/22

7:00 am-5:50 pm

1 stop12h 50m

$452

San DiegoQuito

SAN - UIO

SANUIO

San Diego

Mon 11/10

8:10 pm-5:32 pm

1 stop18h 22m

Quito Mariscal Sucr

Fri 11/21

6:04 am-5:03 pm

1 stop13h 59m

$460

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 8/17

9:03 pm-11:08 pm

1 stop23h 05m

Santiago Arturo Merino Benitez

Tue 9/2

11:29 am-5:50 pm

1 stop33h 21m

$469

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from San Diego to South America

Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to South America

What is the cheapest month to book a flight from San Diego to South America?

Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SA?

Find hourly flight availability from San Diego to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 11, 2025.

When flying from San Diego to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 11, 2025.
See what other customers who have flown with Alaska Airlines, Delta, and LATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,952 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
LATAM Airlines
7.5
Good
1,807 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Copa Airlines
7.5
Good
1,474 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Aeromexico
7.5
Good
1,719 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Boarding

8.1

Comfort

7.8

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to South America?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to South America from San Diego.

  • What are the cheapest airlines to fly from San Diego to South America one-way?

    The cheapest airlines for a one-way flight from San Diego to South America are Spirit Airlines ($166), Copa Airlines ($183), and LATAM Airlines ($228).

  • What are the most popular routes from San Diego to South America?

    The most popular route from San Diego to South America is San Diego - Medellín Jose Maria Cordova Intl. You may also consider San Diego - Buenos Aires Ministro Pistarini or San Diego - Santiago Arturo Merino Benitez.

  • Can I find deals for flights from San Diego to South America that include hotel bookings?

    Yes. In addition to deals on San Diego to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to South America.

  • Can I find deals for business class flights from San Diego to South America?

    Yes. Cheapflights offers flight deals from San Diego to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to South America?

    Currently, May is the cheapest month in which you can book a flight from San Diego to South America (average of $359). Flying from San Diego to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to South America

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Los Angeles to Newark flights
Los Angeles to Seattle flights
Los Angeles to Haneda flights
Los Angeles to Honolulu flights
Los Angeles to Dallas/Fort Worth flights
Los Angeles to Narita flights
San Francisco to John F Kennedy Intl flights
Los Angeles to O'Hare Intl flights
San Francisco to Seattle flights
San Francisco to Newark flights
Los Angeles to LaGuardia flights
San Francisco to Las Vegas flights
Los Angeles to Las Vegas flights
Ontario to Seattle flights
Los Angeles to Portland flights
Los Angeles to Boston flights
Santa Ana to Las Vegas flights
Los Angeles to Cancún flights
Los Angeles to San Francisco flights
Los Angeles to Mexico City flights
Santa Ana to Seattle flights
San Francisco to Honolulu flights
San Francisco to Los Angeles flights
Los Angeles to Miami flights
Burbank to Las Vegas flights
San Francisco to Haneda flights
San Francisco to O'Hare Intl flights
Los Angeles to San Jose flights
Oakland to Las Vegas flights
San Francisco to Narita flights
San Francisco to LaGuardia flights
Los Angeles to Orlando flights
San Jose to Los Angeles flights
Los Angeles to Kahului flights
Burbank to Newark flights
Ontario to John F Kennedy Intl flights
Santa Ana to San Francisco flights
Oakland to Los Angeles flights
Los Angeles to Manila flights
San Jose to Seattle flights
Los Angeles to Denver flights
Los Angeles to Oakland flights
Los Angeles to Fort Lauderdale flights
Los Angeles to San José del Cabo flights
Oakland to Seattle flights
San Jose to Las Vegas flights
Santa Ana to Newark flights
Los Angeles to Hobby flights
San Francisco to Dallas/Fort Worth flights

Top 6 airlines flying from San Diego to South America

Discover the top 6 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$337Average$682FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$395Average$440FlexibilityNo cancel feeOn-time65%
DeltaCheapest$430Average$1,026FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$433Average$944FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$435Average$912FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$449Average$895FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.