$220+ Cheap flights from San Diego (SAN) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Dec 5 — Dec 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Diego to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to South AmericaExplore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This LATAM Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:15 am -
1 stop12h 35m
Fri 12/1112:00 pm -
1 stop13h 56m
Deal found 11/4![LATAM Airlines logo]()
$555
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:11 pm -
1 stop12h 49m
Fri 12/1112:00 pm -
1 stop13h 56m
Deal found 11/4![LATAM Airlines logo]()
$566
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:09 am -
1 stop21h 51m
Sun 12/68:00 pm -
1 stop18h 23m
Deal found 11/3![Multiple Airlines logo]()
$567
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 pm -
1 stop13h 15m
Fri 12/46:25 pm -
1 stop26h 01m
Deal found 11/4![Copa Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:36 pm -
1 stop16h 24m
Sun 12/612:05 pm -
1 stop14h 53m
Deal found 11/3![Delta logo]()
$589
This LATAM Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:07 am -
2 stops18h 53m
Mon 12/78:35 am -
2 stops18h 03m
Deal found 11/3![LATAM Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:30 pm -
2 stops28h 40m
Fri 12/410:40 am -
3 stops34h 32m
Deal found 11/2![United Airlines logo]()
$593
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop22h 50m
Fri 12/116:10 am -
1 stop14h 16m
Deal found 10/31![Copa Airlines logo]()
$594
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:30 pm -
1 stop9h 25m
Tue 12/156:20 pm -
1 stop26h 06m
Deal found 10/31![Copa Airlines logo]()
$595
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop20h 35m
Mon 11/235:20 pm -
1 stop20h 58m
Deal found 11/2![Multiple Airlines logo]()
$598
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:04 pm -
1 stop28h 06m
Tue 11/1010:40 am -
1 stop10h 13m
Deal found 11/3![United Airlines logo]()
$600
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:30 pm -
1 stop30h 45m
Mon 12/76:25 am -
1 stop14h 01m
Deal found 10/31![Copa Airlines logo]()
$602
Best flights from San Diego to South AmericaDiscover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:15 am -
1 stop12h 35m
Wed 3/312:00 pm -
1 stop14h 22m
Deal found 11/4![LATAM Airlines logo]()
$526
This Avianca deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2112:34 pm -
1 stop19h 11m
Fri 1/298:00 pm -
1 stop19h 55m
Deal found 11/1![Multiple Airlines logo]()
$567
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2310:30 pm -
1 stop18h 30m
Sat 1/304:30 pm -
1 stop27h 52m
Deal found 11/2![Copa Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/246:15 am -
1 stop12h 35m
Tue 3/912:50 am -
1 stop17h 30m
Deal found 11/4![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:41 pm -
2 stops23h 29m
Thu 2/1110:40 am -
2 stops24h 56m
Deal found 11/3![United Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:45 pm -
1 stop21h 41m
Wed 12/93:31 pm -
2 stops21h 52m
Deal found 11/2![American Airlines logo]()
$662
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop8h 15m
Mon 11/3010:45 am -
1 stop9h 30m
Deal found 11/4![Copa Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:59 am -
1 stop20h 01m
Fri 1/2212:05 pm -
1 stop14h 53m
Deal found 11/3![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/28:50 pm -
2 stops22h 20m
Wed 5/269:45 am -
1 stop14h 08m
Deal found 11/1![United Airlines logo]()
$593
This GOL deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/612:53 pm -
1 stop15h 27m
Wed 4/1410:10 pm -
1 stop17h 06m
Deal found 10/31![GOL logo]()
$1,212
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 pm -
1 stop15h 30m
Sat 12/510:45 am -
1 stop9h 41m
Deal found 11/2![Copa Airlines logo]()
$576
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2010:20 pm -
2 stops20h 30m
Wed 1/2712:10 pm -
1 stop14h 23m
Deal found 11/3![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/171:20 pm -
1 stop29h 50m
Sun 2/710:40 am -
2 stops24h 57m
Deal found 10/31![United Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:15 pm -
2 stops16h 33m
Fri 1/293:48 pm -
2 stops21h 42m
Deal found 11/3![American Airlines logo]()
$670
This Justfly.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:03 pm -
2 stops27h 57m
Wed 1/205:20 pm -
1 stop22h 38m
Deal found 10/31![Multiple Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1610:00 am -
1 stop20h 05m
Thu 4/2912:50 am -
1 stop16h 30m
Deal found 11/4![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:00 pm -
1 stop26h 10m
Sun 12/610:40 am -
2 stops26h 10m
Deal found 10/31![United Airlines logo]()
$605
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:30 pm -
1 stop8h 15m
Sat 12/126:20 pm -
1 stop26h 06m
Deal found 11/4![Copa Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1310:40 pm -
2 stops21h 00m
Mon 4/2612:15 am -
2 stops17h 26m
Deal found 11/4![Delta logo]()
$593
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/126:25 pm -
2 stops24h 45m
Mon 2/1510:40 am -
2 stops29h 59m
Deal found 11/3![United Airlines logo]()
$613
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:25 pm -
2 stops15h 12m
Sun 12/208:00 am -
1 stop18h 59m
Deal found 11/1![American Airlines logo]()
$768
This Booking.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:09 am -
2 stops25h 26m
Sat 12/53:30 am -
2 stops18h 59m
Deal found 11/3![Multiple Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:20 am -
1 stop23h 40m
Sun 1/2411:40 pm -
1 stop13h 20m
Deal found 11/4![Delta logo]()
$594
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1210:30 pm -
1 stop9h 30m
Sun 2/216:25 am -
1 stop14h 03m
Deal found 11/2![Copa Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/274:05 pm -
2 stops28h 50m
Tue 3/21:50 am -
2 stops21h 54m
Deal found 11/2![United Airlines logo]()
$630
This Copa Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:30 pm -
1 stop9h 30m
Sun 12/209:15 am -
1 stop11h 11m
Deal found 11/1![Copa Airlines logo]()
$688
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/22:00 pm -
1 stop13h 00m
Mon 5/1012:15 am -
2 stops20h 27m
Deal found 11/1![Delta logo]()
$626
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/228:00 am -
1 stop11h 10m
Thu 2/2510:40 am -
2 stops26h 14m
Deal found 11/3![United Airlines logo]()
$651
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/272:33 pm -
1 stop20h 52m
Fri 12/118:35 am -
2 stops18h 03m
Deal found 10/31![Delta logo]()
$631
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:30 pm -
1 stop12h 39m
Wed 12/98:29 am -
1 stop11h 57m
Deal found 11/2![Copa Airlines logo]()
$696
Last-minute flights from San Diego to South AmericaDiscover last-minute flight deals from San Diego to South America. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South America. Data last updated November 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/63:04 pm -
1 stop28h 06m
Tue 11/1010:40 am -
1 stop10h 13m
Deal found 11/3![United Airlines logo]()
$600
This Avianca deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop20h 35m
Mon 11/235:20 pm -
1 stop20h 58m
Deal found 11/2![Multiple Airlines logo]()
$598
This Copa Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 pm -
1 stop13h 15m
Fri 12/46:25 pm -
1 stop26h 01m
Deal found 11/4![Copa Airlines logo]()
$576
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:30 pm -
2 stops28h 40m
Fri 12/410:40 am -
2 stops27h 35m
Deal found 11/2![United Airlines logo]()
$593
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop22h 50m
Fri 12/116:10 am -
1 stop14h 16m
Deal found 10/31![Copa Airlines logo]()
$594
This LATAM Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:15 am -
1 stop12h 35m
Fri 12/1112:00 pm -
1 stop13h 56m
Deal found 11/4![LATAM Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:36 pm -
1 stop16h 24m
Sun 12/612:05 pm -
1 stop14h 53m
Deal found 11/3![Delta logo]()
$589
This LATAM Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:07 am -
2 stops18h 53m
Sun 12/612:05 pm -
1 stop14h 53m
Deal found 11/3![LATAM Airlines logo]()
$593
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:11 pm -
1 stop12h 49m
Fri 12/1112:00 pm -
1 stop13h 56m
Deal found 11/4![LATAM Airlines logo]()
$566
This Avianca deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:09 am -
1 stop21h 51m
Sun 12/68:00 pm -
1 stop18h 23m
Deal found 11/3![Multiple Airlines logo]()
$567
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:30 pm -
1 stop30h 45m
Mon 12/76:25 am -
1 stop14h 01m
Deal found 10/31![Copa Airlines logo]()
$602
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:30 pm -
1 stop9h 25m
Tue 12/156:20 pm -
1 stop26h 06m
Deal found 10/31![Copa Airlines logo]()
$595
One-way flights from San Diego to South AmericaSearch for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:37 pm -
2 stops36h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:25 am -
2 stops26h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:53 pm -
2 stops19h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:02 pm -
3 stops43h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:49 am -
2 stops23h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:51 pm -
2 stops37h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/188:30 am -
3 stops36h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/249:11 pm -
2 stops35h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/203:30 pm -
3 stops42h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:20 am -
2 stops25h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:45 pm -
2 stops18h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/244:16 pm -
2 stops40h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$279
Find flight deals from San Diego to South America
Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated November 5, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $526 (FlightHub) |
One-way from | $220 (Kiwi.com) |
Popular in | December |
Cheapest in | July |
Average price | $797 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from San Diego to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 1/20
3:30 pm-12:55 pm
3 stops42h 25m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$248
San DiegoBogotá
SAN San Diego - BOG Bogotá El Dorado
SANBOG
San Diego
Fri 12/25
7:20 am-11:51 am
2 stops25h 31m
Bogotá El Dorado
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$249
Quickest round-trip
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 1/20
10:30 pm-9:45 am
1 stop8h 15m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Sun 1/3
10:30 pm-5:00 pm
1 stop15h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoQuito
SAN San Diego - UIO Quito Mariscal Sucr
SANUIO
San Diego
Sat 1/16
7:00 am-6:35 am
1 stop20h 35m
Quito Mariscal Sucr
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$284
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 1/20
6:23 pm-10:10 pm
2 stops24h 47m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$287
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Sat 2/13
10:47 pm-11:10 pm
1 stop21h 23m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$299
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Thu 11/12
3:04 pm-10:10 pm
1 stop28h 06m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$305
San DiegoCartagena
SAN San Diego - CTG Cartagena Rafael Nunez
SANCTG
San Diego
Fri 2/12
10:30 pm-11:00 am
1 stop9h 30m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$310
San DiegoQuito
SAN San Diego - UIO Quito Mariscal Sucr
SANUIO
San Diego
Sat 1/16
10:30 pm-12:32 am
1 stop23h 02m
Quito Mariscal Sucr
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$310
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
SAN-LIM
SAN-GYE
SAN-MDE
SAN-BOG
SAN-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South America
SAN-0SA
SAN-LIM
SAN-GYE
SAN-MDE
SAN-BOG
What is the cheapest month to book a flight from San Diego to South America?
Currently, February is the cheapest month in which you can book a flight from San Diego to South America (average of $642). Flying from San Diego to South America in December is currently the most expensive (average of $1,220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Diego to South America?
The best time to book flights from San Diego to South America is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 5, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Entertainment
7.8
Overall
7.8
Comfort
7.8
Food
7.2
Boarding
8.1
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for San Diego to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South America by cabin class
Find flights from San Diego to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South America flights
Browse other San Diego and South America flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
San Diego to South America flights
Consider these flights traveling from San Diego to South America.
Top 7 airlines flying from San Diego to South America
Discover the top 7 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$927 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$332 | Average$647 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$352 | Average$951 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$958 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$464 | Average$756 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$516 | Average$783 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$695 | Average$1,466 | FlexibilityNo cancel fee | On-time74% |