$192+ Cheap flights from San Diego (SAN) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — BOG
Sep 10 — Sep 171
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to South AmericaExplore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
Explore the most affordable flight options available from San Diego to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2026.
This eDestinos deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:20 pm -
1 stop13h 55m
Wed 9/304:50 pm -
1 stop28h 45m
Deal found 8/6![Multiple Airlines logo]()
$378
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:22 pm -
1 stop28h 08m
Tue 10/2711:15 pm -
1 stop17h 20m
Deal found 8/10![Multiple Airlines logo]()
$428
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am -
1 stop21h 15m
Tue 10/204:50 pm -
1 stop23h 45m
Deal found 8/10![Multiple Airlines logo]()
$437
This SmartFares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop21h 15m
Tue 9/1511:15 pm -
1 stop22h 20m
Deal found 8/9![Multiple Airlines logo]()
$446
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:22 pm -
1 stop13h 53m
Sun 10/257:05 am -
1 stop14h 07m
Deal found 8/10![Multiple Airlines logo]()
$452
This eDestinos deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop24h 10m
Tue 9/152:10 pm -
2 stops20h 38m
Deal found 8/9![Multiple Airlines logo]()
$454
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 am -
1 stop34h 25m
Thu 11/195:00 pm -
1 stop22h 54m
Deal found 8/10![Multiple Airlines logo]()
$457
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am -
1 stop21h 15m
Tue 9/294:50 pm -
1 stop18h 18m
Deal found 8/7![Multiple Airlines logo]()
$458
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am -
1 stop26h 20m
Sun 10/188:00 pm -
1 stop20h 35m
Deal found 8/10![Multiple Airlines logo]()
$459
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:47 am -
1 stop17h 28m
Wed 11/411:15 pm -
1 stop24h 05m
Deal found 8/7![Multiple Airlines logo]()
$463
This Trip.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop24h 10m
Wed 10/2110:40 pm -
1 stop17h 55m
Deal found 8/9![Multiple Airlines logo]()
$466
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
1 stop26h 20m
Sun 10/2510:45 pm -
2 stops22h 27m
Deal found 8/10![Multiple Airlines logo]()
$469
Best flights from San Diego to South AmericaDiscover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
Discover carefully curated flight deals from San Diego to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 11, 2026.
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:51 pm -
2 stops16h 19m
Wed 10/218:50 pm -
2 stops24h 22m
Deal found 8/6![Multiple Airlines logo]()
$499
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:00 pm -
1 stop16h 55m
Sun 9/206:20 pm -
1 stop26h 09m
Deal found 8/6![Copa Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:16 am -
1 stop8h 59m
Thu 11/510:40 am -
1 stop13h 46m
Deal found 8/7![United Airlines logo]()
$613
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:30 pm -
2 stops19h 50m
Thu 11/1911:40 pm -
1 stop16h 13m
Deal found 8/6![Delta logo]()
$615
This GOL deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:50 pm -
1 stop15h 10m
Thu 10/2912:05 am -
1 stop15h 51m
Deal found 8/11![GOL logo]()
$864
This oojo deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/110:55 am -
2 stops23h 05m
Wed 2/31:40 pm -
2 stops25h 50m
Deal found 8/6![LATAM Airlines logo]()
$939
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:00 pm -
1 stop8h 15m
Wed 10/2810:45 am -
1 stop9h 42m
Deal found 8/8![Copa Airlines logo]()
$515
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:00 pm -
1 stop16h 00m
Sat 11/285:00 am -
1 stop15h 15m
Deal found 8/10![Copa Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:15 am -
2 stops12h 55m
Mon 10/59:45 am -
1 stop13h 39m
Deal found 8/10![United Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:30 pm -
1 stop19h 45m
Fri 9/49:00 am -
1 stop16h 00m
Deal found 8/8![Delta logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1110:00 pm -
1 stop12h 25m
Sun 10/254:40 pm -
1 stop27h 47m
Deal found 8/6![Copa Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:16 am -
1 stop8h 59m
Wed 11/410:40 am -
2 stops12h 44m
Deal found 8/7![United Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:25 pm -
1 stop18h 50m
Tue 9/12:55 pm -
1 stop20h 31m
Deal found 8/7![Delta logo]()
$664
This Copa Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:00 pm -
1 stop18h 15m
Sun 11/293:30 am -
1 stop16h 45m
Deal found 8/7![Copa Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:05 am -
1 stop11h 10m
Wed 11/410:40 am -
2 stops14h 50m
Deal found 8/7![United Airlines logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:00 pm -
1 stop11h 25m
Fri 11/272:35 am -
1 stop17h 40m
Deal found 8/6![Copa Airlines logo]()
$549
This LATAM Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:24 pm -
2 stops27h 31m
Mon 10/195:50 pm -
2 stops29h 24m
Deal found 8/9![Multiple Airlines logo]()
$825
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:00 am -
1 stop11h 10m
Sun 9/209:45 am -
1 stop13h 39m
Deal found 8/10![United Airlines logo]()
$635
This Copa Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:00 pm -
1 stop24h 55m
Sun 10/252:35 am -
1 stop17h 52m
Deal found 8/8![Copa Airlines logo]()
$549
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:45 am -
2 stops13h 50m
Wed 11/41:30 am -
1 stop14h 54m
Deal found 8/7![United Airlines logo]()
$635
This LATAM Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/196:20 am -
2 stops19h 20m
Tue 2/95:55 pm -
2 stops21h 35m
Deal found 8/6![LATAM Airlines logo]()
$945
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:20 am -
1 stop19h 20m
Thu 10/299:30 pm -
1 stop22h 55m
Deal found 8/9![Delta logo]()
$824
This Copa Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:00 pm -
1 stop16h 55m
Mon 8/315:00 am -
1 stop15h 30m
Deal found 8/9![Copa Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:30 am -
2 stops20h 24m
Fri 9/48:30 am -
1 stop11h 16m
Deal found 8/10![United Airlines logo]()
$640
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:53 am -
1 stop14h 47m
Thu 10/1510:50 pm -
1 stop26h 28m
Deal found 8/9![Delta logo]()
$824
This LATAM Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:00 pm -
2 stops21h 00m
Thu 10/293:50 pm -
2 stops22h 27m
Deal found 8/7![LATAM Airlines logo]()
$998
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:04 pm -
1 stop11h 50m
Fri 9/412:14 am -
2 stops22h 31m
Deal found 8/8![United Airlines logo]()
$640
This GOL deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:56 pm -
2 stops29h 59m
Tue 10/2710:35 am -
2 stops29h 21m
Deal found 8/9![GOL logo]()
$1,136
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:00 pm -
1 stop23h 40m
Tue 10/62:15 am -
1 stop18h 15m
Deal found 8/10![Copa Airlines logo]()
$583
This LATAM Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:57 am -
2 stops26h 33m
Sat 11/148:05 pm -
2 stops19h 18m
Deal found 8/7![LATAM Airlines logo]()
$998
Last-minute flights from San Diego to South AmericaDiscover last-minute flight deals from San Diego to South America. Data last updated August 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South America. Data last updated August 11, 2026 and is based on user searches.
This oojo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:20 pm -
1 stop13h 05m
Fri 8/282:10 pm -
2 stops20h 38m
Deal found 8/8![Multiple Airlines logo]()
$491
This SmartFares deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop21h 15m
Tue 9/1511:15 pm -
1 stop22h 20m
Deal found 8/9![Multiple Airlines logo]()
$446
This eDestinos deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop24h 10m
Tue 9/152:10 pm -
2 stops20h 38m
Deal found 8/9![Multiple Airlines logo]()
$454
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:00 am -
1 stop21h 15m
Tue 10/204:50 pm -
1 stop23h 45m
Deal found 8/10![Multiple Airlines logo]()
$437
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:20 pm -
1 stop13h 55m
Sun 9/277:10 am -
1 stop14h 25m
Deal found 8/10![Multiple Airlines logo]()
$488
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:59 pm -
2 stops15h 11m
Sun 9/274:50 am -
2 stops16h 45m
Deal found 8/10![Multiple Airlines logo]()
$499
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am -
1 stop21h 15m
Tue 9/294:50 pm -
1 stop18h 18m
Deal found 8/7![Multiple Airlines logo]()
$458
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:00 am -
1 stop27h 25m
Wed 9/302:00 pm -
1 stop32h 36m
Deal found 8/7![Multiple Airlines logo]()
$463
This FlightHub deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/229:30 pm -
1 stop30h 45m
Thu 10/12:00 pm -
1 stop32h 36m
Deal found 8/7![Multiple Airlines logo]()
$468
This eDestinos deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:20 pm -
1 stop13h 55m
Wed 9/304:50 pm -
1 stop28h 45m
Deal found 8/6![Multiple Airlines logo]()
$378
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:20 pm -
2 stops20h 50m
Thu 10/12:10 pm -
2 stops20h 38m
Deal found 8/10![Multiple Airlines logo]()
$511
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/272:20 pm -
1 stop16h 50m
Sat 10/32:10 pm -
2 stops20h 35m
Deal found 8/10![Multiple Airlines logo]()
$504
One-way flights from San Diego to South AmericaSearch for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
Search for one-way flight options from San Diego to South America. Find affordable one-way fares based on user searches. Data last updated August 11, 2026.
This Avianca deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:22 pm -
1 stop13h 53m
Deal found 8/6![Multiple Airlines logo]()
$192
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:20 pm -
1 stop20h 05m
Deal found 8/10![Multiple Airlines logo]()
$196
This Viajes Falabella deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Viajes Falabella is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/249:30 pm -
1 stop20h 55m
Deal found 8/7![Multiple Airlines logo]()
$199
This Despegar deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:23 am -
1 stop17h 52m
Deal found 8/6![Multiple Airlines logo]()
$200
This Avianca deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:20 pm -
1 stop13h 05m
Deal found 8/7![Multiple Airlines logo]()
$201
This oojo deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:20 pm -
1 stop19h 00m
Deal found 8/11![Multiple Airlines logo]()
$206
This FlightHub deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop21h 15m
Deal found 8/10![Multiple Airlines logo]()
$212
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:22 pm -
1 stop18h 58m
Deal found 8/6![Multiple Airlines logo]()
$221
This Avianca deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:59 pm -
2 stops14h 01m
Deal found 8/9![Multiple Airlines logo]()
$221
This FlightHub deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:20 pm -
1 stop16h 50m
Deal found 8/9![Multiple Airlines logo]()
$222
This Avianca deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:18 pm -
2 stops13h 42m
Deal found 8/10![Multiple Airlines logo]()
$225
This oojo deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:00 am -
2 stops17h 00m
Deal found 8/10![Multiple Airlines logo]()
$226
Find flight deals from San Diego to South America
Keep the following information in mind while searching for San Diego to South America flight deals. Data was last updated August 11, 2026.
Round-trip from | $378 (eDestinos) |
|---|---|
One-way from | $192 (Avianca) |
Popular in | July |
Cheapest in | November |
Average price | $540 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
Use the filters below to find and compare flights from San Diego to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Fri 10/16
6:51 pm-1:10 pm
2 stops16h 19m
Medellín Jose Maria Cordova Intl
Wed 10/21
8:50 pm-7:12 pm
2 stops24h 22m
$499
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 9/16
10:00 pm-4:55 pm
1 stop16h 55m
Medellín Jose Maria Cordova Intl
Sun 9/20
6:20 pm-6:29 pm
1 stop26h 09m
$515
Quickest round-trip
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 10/21
10:00 pm-8:15 am
1 stop8h 15m
Medellín Jose Maria Cordova Intl
Wed 10/28
10:45 am-6:27 pm
1 stop9h 42m
$515
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Sat 11/21
10:00 pm-5:00 pm
1 stop16h 00m
Medellín Jose Maria Cordova Intl
Sat 11/28
5:00 am-5:15 pm
1 stop15h 15m
$515
San DiegoLima
SAN San Diego - LIM Lima J Chavez Intl
SANLIM
San Diego
Sun 10/11
10:00 pm-12:25 pm
1 stop12h 25m
Lima J Chavez Intl
Sun 10/25
4:40 pm-6:27 pm
1 stop27h 47m
$549
San DiegoLima
SAN San Diego - LIM Lima J Chavez Intl
SANLIM
San Diego
Sat 11/21
10:00 pm-7:15 pm
1 stop18h 15m
Lima J Chavez Intl
Sun 11/29
3:30 am-5:15 pm
1 stop16h 45m
$549
San DiegoLima
SAN San Diego - LIM Lima J Chavez Intl
SANLIM
San Diego
Sat 11/21
10:00 pm-12:25 pm
1 stop11h 25m
Lima J Chavez Intl
Fri 11/27
2:35 am-5:15 pm
1 stop17h 40m
$549
San DiegoLima
SAN San Diego - LIM Lima J Chavez Intl
SANLIM
San Diego
Sun 10/18
10:00 pm-12:55 am
1 stop24h 55m
Lima J Chavez Intl
Sun 10/25
2:35 am-6:27 pm
1 stop17h 52m
$549
San DiegoMedellín
SAN San Diego - MDE Medellín Jose Maria Cordova Intl
SANMDE
San Diego
Wed 8/26
10:00 pm-4:55 pm
1 stop16h 55m
Medellín Jose Maria Cordova Intl
Mon 8/31
5:00 am-6:30 pm
1 stop15h 30m
$565
San DiegoLima
SAN San Diego - LIM Lima J Chavez Intl
SANLIM
San Diego
Wed 9/30
10:00 pm-11:40 pm
1 stop23h 40m
Lima J Chavez Intl
Tue 10/6
2:15 am-6:30 pm
1 stop18h 15m
$583
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South America
Have a flexible travel schedule? Discover the best time to fly to South America from San Diego with our price prediction graph.
SAN-BOG
SAN-MDE
SAN-LIM
SAN-SCL
SAN-VCP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South America
SAN-0SA
SAN-BOG
SAN-MDE
SAN-LIM
SAN-SCL
What is the cheapest month to book a flight from San Diego to South America?
Currently, October is the cheapest month in which you can book a flight from San Diego to South America (average of $618). Flying from San Diego to South America in December is currently the most expensive (average of $1,121). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from San Diego to South America?
The best time to book flights from San Diego to South America is 43 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated August 11, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Food
7.2
Crew
8.5
Comfort
7.8
Overall
7.8
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South America by cabin class
Find flights from San Diego to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South America flights
Browse other San Diego and South America flight options. Last updated on August 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
San Diego to South America flights
Consider these flights traveling from San Diego to South America.
Top 7 airlines flying from San Diego to South America
Discover the top 7 airlines that operate flights from San Diego to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$253 | Average$904 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$311 | Average$613 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$437 | Average$885 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$445 | Average$731 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$516 | Average$783 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$524 | Average$958 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$695 | Average$1,416 | FlexibilityNo cancel fee | On-time74% |