$357+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
May 28 — Jun 41
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Justfly.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:00 am
SAN
- SCL
1 stop16h 35m
LATAM Airlines
Fri 8/2111:25 pm
SCL
- SAN
1 stop18h 54m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$691
This Justfly.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:00 am
SAN
- SCL
1 stop15h 35m
LATAM Airlines
Wed 10/711:25 pm
SCL
- SAN
1 stop15h 05m
LATAM Airlines
Deal found 4/28![LATAM Airlines logo]()
$756
This FlightHub deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 am
SAN
- SCL
2 stops19h 35m
LATAM Airlines
Tue 6/911:25 pm
SCL
- SAN
1 stop22h 51m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$758
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:15 am
SAN
- SCL
2 stops20h 10m
LATAM Airlines
Fri 6/124:10 am
SCL
- SAN
2 stops22h 26m
LATAM Airlines
Deal found 4/23![LATAM Airlines logo]()
$766
This Justfly.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am
SAN
- SCL
2 stops18h 10m
LATAM Airlines
Tue 11/107:45 am
SCL
- SAN
2 stops20h 10m
LATAM Airlines
Deal found 4/23![LATAM Airlines logo]()
$771
This LATAM Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:18 pm
SAN
- SCL
2 stops36h 42m
Multiple Airlines
Thu 8/2011:25 pm
SCL
- SAN
1 stop15h 10m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$773
This LATAM Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:15 am
SAN
- SCL
1 stop20h 20m
LATAM Airlines
Mon 6/155:40 am
SCL
- SAN
2 stops20h 56m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$775
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
SAN
- SCL
2 stops21h 10m
Delta
Fri 8/2111:25 pm
SCL
- SAN
1 stop14h 02m
Delta
Deal found 4/27![Delta logo]()
$777
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:30 pm
SAN
- SCL
1 stop29h 45m
Delta
Sun 8/1611:25 pm
SCL
- SAN
1 stop18h 54m
Delta
Deal found 4/24![Delta logo]()
$778
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Justfly.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:00 am
SAN
- SCL
1 stop15h 35m
LATAM Airlines
Wed 10/711:25 pm
SCL
- SAN
1 stop15h 05m
LATAM Airlines
Deal found 4/27![LATAM Airlines logo]()
$756
This LATAM Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:18 pm
SAN
- SCL
2 stops36h 42m
Multiple Airlines
Thu 8/2011:25 pm
SCL
- SAN
1 stop15h 10m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$773
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:15 am
SAN
- SCL
2 stops21h 10m
Delta
Fri 8/2111:25 pm
SCL
- SAN
1 stop14h 02m
Delta
Deal found 4/27![Delta logo]()
$777
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/712:36 pm
SAN
- SCL
1 stop15h 29m
American Airlines
Sun 6/149:00 pm
SCL
- SAN
1 stop17h 18m
American Airlines
Deal found 4/23![American Airlines logo]()
$792
This KAYAK deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:00 am
SAN
- SCL
1 stop16h 35m
LATAM Airlines
Fri 8/214:30 pm
SCL
- SAN
2 stops33h 14m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$772
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:30 pm
SAN
- SCL
1 stop29h 45m
Delta
Sun 8/1611:25 pm
SCL
- SAN
1 stop18h 54m
Delta
Deal found 4/24![Delta logo]()
$778
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:15 am
SAN
- SCL
2 stops20h 50m
American Airlines
Sun 5/319:00 pm
SCL
- SAN
1 stop17h 18m
American Airlines
Deal found 4/25![American Airlines logo]()
$814
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:15 am
SAN
- SCL
1 stop20h 20m
LATAM Airlines
Tue 9/1511:00 pm
SCL
- SAN
2 stops23h 23m
LATAM Airlines
Deal found 4/23![LATAM Airlines logo]()
$778
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:15 am
SAN
- SCL
1 stop20h 20m
Delta
Mon 6/1510:55 pm
SCL
- SAN
1 stop24h 39m
Delta
Deal found 4/24![Delta logo]()
$809
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated April 28, 2026 and is based on user searches.
This BusinessClass deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:45 pm
SAN
- SCL
2 stops30h 20m
GOL
Thu 5/148:35 pm
SCL
- SAN
2 stops28h 20m
GOL
Deal found 4/26![GOL logo]()
$920
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:59 am
SAN
- SCL
1 stop15h 36m
Delta
Tue 5/197:55 pm
SCL
- SAN
2 stops22h 02m
Delta
Deal found 4/28![Delta logo]()
$836
This Trip.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:00 pm
SAN
- SCL
1 stop21h 43m
Multiple Airlines
Mon 5/183:20 pm
SCL
- SAN
3 stops54h 19m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$859
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:53 pm
SAN
- SCL
1 stop15h 12m
American Airlines
Tue 5/198:35 pm
SCL
- SAN
1 stop17h 41m
American Airlines
Deal found 4/24![American Airlines logo]()
$871
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:36 pm
SAN
- SCL
1 stop15h 29m
American Airlines
Thu 5/289:00 pm
SCL
- SAN
1 stop17h 18m
American Airlines
Deal found 4/23![American Airlines logo]()
$809
This SmartFares deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/243:15 pm
SAN
- SCL
1 stop35h 20m
LATAM Airlines
Sun 5/3111:25 pm
SCL
- SAN
1 stop21h 38m
LATAM Airlines
Deal found 4/26![LATAM Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:25 pm
SAN
- SCL
1 stop29h 50m
Delta
Sun 5/3110:55 pm
SCL
- SAN
1 stop24h 40m
Delta
Deal found 4/26![Delta logo]()
$815
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:06 pm
SAN
- SCL
2 stops27h 49m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$357
This Copa Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1510:00 pm
SAN
- SCL
1 stop18h 23m
Copa Airlines
Deal found 4/26![Copa Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
SAN
- SCL
2 stops21h 50m
American Airlines
Deal found 4/24![American Airlines logo]()
$416
This eDestinos deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:25 am
SAN
- SCL
3 stops40h 55m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:25 am
SAN
- SCL
3 stops52h 05m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/149:28 am
SAN
- SCL
2 stops18h 37m
American Airlines
Deal found 4/26![American Airlines logo]()
$438
This BusinessClass deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:28 pm
SAN
- SCL
2 stops29h 37m
GOL
Deal found 4/26![GOL logo]()
$443
This eDestinos deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:13 am
SAN
- SCL
3 stops24h 17m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$450
This eDestinos deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/79:53 pm
SAN
- SCL
3 stops59h 42m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$492
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $758 (FlightHub) |
One-way from | $357 (Kiwi.com) |
Popular in | August |
Cheapest in | September |
Average price | $775 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 9/28
10:00 am-5:35 am
1 stop15h 35m
Santiago Arturo Merino Benitez
Wed 10/7
11:25 pm-10:30 am
1 stop15h 05m
$756
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 8/14
10:00 am-5:35 am
1 stop16h 35m
Santiago Arturo Merino Benitez
Fri 8/21
4:30 pm-10:44 pm
2 stops33h 14m
$772
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Thu 7/30
2:18 pm-6:00 am
2 stops36h 42m
Santiago Arturo Merino Benitez
Thu 8/20
11:25 pm-11:35 am
1 stop15h 10m
$773
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 8/14
6:15 am-6:25 am
2 stops21h 10m
Santiago Arturo Merino Benitez
Fri 8/21
11:25 pm-10:27 am
1 stop14h 02m
$777
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sat 8/8
10:30 pm-7:15 am
1 stop29h 45m
Santiago Arturo Merino Benitez
Sun 8/16
11:25 pm-3:19 pm
1 stop18h 54m
$778
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 9/1
6:15 am-5:35 am
1 stop20h 20m
Santiago Arturo Merino Benitez
Tue 9/15
11:00 pm-6:23 pm
2 stops23h 23m
$778
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sun 6/7
12:36 pm-7:05 am
1 stop15h 29m
Santiago Arturo Merino Benitez
Sun 6/14
9:00 pm-11:18 am
1 stop17h 18m
$792
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 6/8
6:15 am-5:35 am
1 stop20h 20m
Santiago Arturo Merino Benitez
Mon 6/15
10:55 pm-8:34 pm
1 stop24h 39m
$809
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 5/26
7:15 am-7:05 am
2 stops20h 50m
Santiago Arturo Merino Benitez
Sun 5/31
9:00 pm-11:18 am
1 stop17h 18m
$814
Cheapest one-way
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 5/27
10:00 pm-7:23 pm
1 stop18h 23m
$413
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
How far ahead should I book a flight from San Diego to Santiago?
Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, September is the cheapest month in which you can book a flight from San Diego to Santiago (average of $573). Flying from San Diego to Santiago in August is currently the most expensive (average of $1,500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 28, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Food
7.2
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Santiago by cabin class
Find flights from San Diego to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Santiago flights
Browse other San Diego and Santiago flight options. Last updated on April 28, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Top 5 airlines flying from San Diego to Santiago
Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$453 | Average$550 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$504 | Average$876 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$965 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$574 | Average$941 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$574 | Average$734 | FlexibilityNo cancel fee | On-time69% |