$365+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Nov 28 — Dec 51
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Santiago with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Santiago
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Best
Last-minute
One-way
Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2711:05 am -
1 stop13h 30m
Fri 12/48:40 am -
2 stops19h 16m
Deal found 10/28![LATAM Airlines logo]()
$775
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
1 stop19h 40m
Tue 11/311:10 pm -
1 stop17h 03m
Deal found 10/26![LATAM Airlines logo]()
$776
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop26h 16m
Thu 12/109:50 pm -
1 stop17h 05m
Deal found 10/24![Multiple Airlines logo]()
$784
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:59 am -
1 stop15h 41m
Wed 11/1811:10 pm -
1 stop25h 31m
Deal found 10/28![LATAM Airlines logo]()
$796
This Justfly.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops17h 45m
Tue 12/19:45 am -
2 stops18h 53m
Deal found 10/28![LATAM Airlines logo]()
$797
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:20 am -
1 stop20h 20m
Wed 12/211:10 pm -
1 stop17h 44m
Deal found 10/27![LATAM Airlines logo]()
$799
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop20h 06m
Fri 12/45:07 am -
1 stop17h 19m
Deal found 10/28![Copa Airlines logo]()
$813
This lastminute.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
2 stops19h 40m
Thu 12/1011:10 pm -
1 stop17h 44m
Deal found 10/24![LATAM Airlines logo]()
$815
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop20h 06m
Fri 12/45:07 am -
1 stop17h 19m
Deal found 10/28![Copa Airlines logo]()
$813
This lastminute.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
2 stops19h 40m
Thu 12/1011:10 pm -
2 stops29h 28m
Deal found 10/24![LATAM Airlines logo]()
$825
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
1 stop20h 20m
Tue 11/2411:50 pm -
1 stop25h 53m
Deal found 10/27![Delta logo]()
$826
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/28:00 am -
1 stop19h 50m
Wed 1/2710:45 pm -
2 stops23h 31m
Deal found 10/27![United Airlines logo]()
$830
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:00 am -
1 stop18h 40m
Tue 12/19:45 am -
2 stops18h 53m
Deal found 10/25![Delta logo]()
$830
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:45 pm -
2 stops33h 05m
Wed 12/1610:45 pm -
2 stops19h 26m
Deal found 10/25![United Airlines logo]()
$830
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1110:30 pm -
1 stop20h 05m
Sun 12/203:19 am -
1 stop19h 07m
Deal found 10/28![Copa Airlines logo]()
$891
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:16 am -
1 stop17h 34m
Wed 11/1810:45 pm -
1 stop22h 09m
Deal found 10/28![United Airlines logo]()
$836
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:45 pm -
2 stops33h 05m
Mon 12/2110:45 pm -
2 stops17h 50m
Deal found 10/28![United Airlines logo]()
$855
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated October 29, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated October 29, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1510:59 am -
1 stop15h 41m
Wed 11/1811:10 pm -
1 stop25h 31m
Deal found 10/28![LATAM Airlines logo]()
$796
This Justfly.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops17h 45m
Tue 12/19:45 am -
2 stops18h 53m
Deal found 10/28![LATAM Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:16 am -
1 stop17h 34m
Tue 12/110:45 pm -
1 stop22h 15m
Deal found 10/29![United Airlines logo]()
$826
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:30 pm -
1 stop26h 16m
Thu 12/109:50 pm -
1 stop17h 05m
Deal found 10/24![Multiple Airlines logo]()
$784
This lastminute.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
2 stops19h 40m
Thu 12/1011:10 pm -
1 stop17h 44m
Deal found 10/24![LATAM Airlines logo]()
$815
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:20 am -
1 stop20h 20m
Wed 12/211:10 pm -
1 stop17h 44m
Deal found 10/27![LATAM Airlines logo]()
$799
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2711:05 am -
1 stop13h 30m
Fri 12/48:40 am -
2 stops19h 16m
Deal found 10/28![LATAM Airlines logo]()
$775
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2710:30 pm -
1 stop20h 06m
Fri 12/45:07 am -
1 stop17h 19m
Deal found 10/28![Copa Airlines logo]()
$813
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1911:15 am -
1 stop13h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![LATAM Airlines logo]()
$365
This eDestinos deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:05 am -
1 stop13h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![LATAM Airlines logo]()
$382
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/73:22 pm -
3 stops25h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![LATAM Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:07 pm -
2 stops29h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$389
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:30 pm -
1 stop26h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Copa Airlines logo]()
$395
This Expedia deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:25 am -
1 stop18h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![LATAM Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:15 am -
1 stop21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$398
This eDestinos deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
1 stop20h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![LATAM Airlines logo]()
$400
This LATAM Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:59 am -
3 stops29h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![LATAM Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:41 pm -
2 stops32h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$404
This eDestinos deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:03 am -
2 stops59h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$406
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $775 (FlightHub) |
One-way from | $365 (FlightHub) |
Popular in | December |
Cheapest in | April |
Average price | $921 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Wed 12/2
10:30 pm-11:35 pm
1 stop20h 05m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$395
Quickest round-trip
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Wed 1/27
10:55 am-7:40 am
1 stop15h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$397
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sun 1/10
8:40 am-8:50 am
2 stops19h 10m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$398
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Tue 1/5
11:15 am-3:00 pm
2 stops22h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$398
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Wed 1/6
6:15 am-7:40 am
1 stop20h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$398
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sat 1/9
7:41 pm-8:50 am
2 stops32h 09m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$404
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sat 12/12
10:30 pm-7:40 am
1 stop28h 10m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$409
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Thu 1/7
10:20 pm-6:40 am
1 stop27h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$409
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sat 12/12
12:39 pm-8:50 am
2 stops39h 11m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$426
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 11/27
10:30 pm-11:36 pm
1 stop20h 06m
Santiago Arturo Merino Benitez
Fri 12/4
5:07 am-5:26 pm
1 stop17h 19m
$813
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $775). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,581). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Airfare is typical for this route at the moment.
San Diego to Santiago flights typically cost between $584 and $1,083 in November.The cheapest round-trip price found within the last 5 days was $775 on LATAM Airlines (Nov 27-Dec 4).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 29, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andUnited Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Entertainment
7.8
Overall
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from San Diego to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Santiago flights
Browse other San Diego and Santiago flight options. Last updated on October 29, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Top 4 airlines flying from San Diego to Santiago
Discover the top 4 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$352 | Average$835 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$555 | Average$762 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$563 | Average$875 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$739 | Average$1,124 | FlexibilityNo cancel fee | On-time71% |