$358+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Santiago
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Best
Last-minute
One-way
Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 pm -
1 stop18h 02m
Sun 9/275:14 am -
1 stop17h 15m
Deal found 9/5![Copa Airlines logo]()
$730
This Justfly.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:15 am -
1 stop18h 20m
Thu 12/311:55 pm -
1 stop15h 30m
Deal found 9/8![LATAM Airlines logo]()
$752
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:30 pm -
1 stop18h 02m
Fri 10/95:22 am -
1 stop17h 08m
Deal found 9/6![Copa Airlines logo]()
$758
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:15 am -
1 stop18h 20m
Tue 12/17:05 pm -
2 stops20h 20m
Deal found 9/9![LATAM Airlines logo]()
$768
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 pm -
1 stop18h 02m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/8![Copa Airlines logo]()
$770
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:10 pm -
1 stop14h 05m
Fri 10/3011:10 pm -
1 stop16h 03m
Deal found 9/8![LATAM Airlines logo]()
$771
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
2 stops20h 45m
Tue 11/38:25 pm -
2 stops18h 47m
Deal found 9/8![LATAM Airlines logo]()
$780
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:00 pm -
1 stop14h 15m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/8![Multiple Airlines logo]()
$782
This Orbitz deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:00 pm -
1 stop14h 15m
Sun 9/2010:20 am -
2 stops37h 06m
Deal found 9/8![LATAM Airlines logo]()
$786
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:30 pm -
1 stop21h 52m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/7![Copa Airlines logo]()
$788
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops20h 15m
Mon 12/711:10 pm -
1 stop17h 44m
Deal found 9/8![Delta logo]()
$818
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:45 am -
2 stops21h 05m
Thu 10/299:45 pm -
1 stop17h 14m
Deal found 9/8![United Airlines logo]()
$840
This LATAM Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:15 am -
3 stops24h 26m
Mon 12/217:05 pm -
2 stops21h 55m
Deal found 9/4![LATAM Airlines logo]()
$1,045
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:15 am -
1 stop19h 25m
Wed 1/2711:55 pm -
1 stop15h 35m
Deal found 9/4![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/210:30 pm -
1 stop27h 10m
Wed 1/277:30 am -
2 stops21h 17m
Deal found 9/7![Delta logo]()
$831
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:15 am -
2 stops19h 20m
Fri 10/98:50 am -
2 stops18h 05m
Deal found 9/6![Delta logo]()
$840
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/71:20 pm -
1 stop14h 30m
Fri 12/2510:45 pm -
1 stop19h 48m
Deal found 9/6![United Airlines logo]()
$1,045
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:10 pm -
2 stops23h 30m
Wed 12/239:55 pm -
2 stops22h 00m
Deal found 9/6![Delta logo]()
$910
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:59 pm -
1 stop32h 36m
Mon 11/308:13 am -
2 stops30h 43m
Deal found 9/9![Delta logo]()
$1,001
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated September 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:00 pm -
1 stop14h 15m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/7![Multiple Airlines logo]()
$792
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 pm -
1 stop18h 02m
Sun 9/275:14 am -
1 stop17h 15m
Deal found 9/5![Copa Airlines logo]()
$730
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:30 pm -
1 stop18h 02m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/8![Copa Airlines logo]()
$770
This Orbitz deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:00 pm -
1 stop14h 15m
Sun 9/2010:20 am -
2 stops37h 06m
Deal found 9/8![LATAM Airlines logo]()
$786
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:00 pm -
1 stop14h 15m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/8![Multiple Airlines logo]()
$782
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:30 pm -
1 stop21h 52m
Sat 9/1912:22 pm -
1 stop34h 07m
Deal found 9/7![Copa Airlines logo]()
$788
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:30 pm -
1 stop18h 02m
Fri 10/95:22 am -
1 stop17h 08m
Deal found 9/6![Copa Airlines logo]()
$758
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:10 pm -
1 stop14h 05m
Fri 10/3011:10 pm -
1 stop16h 03m
Deal found 9/8![LATAM Airlines logo]()
$771
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am -
2 stops20h 45m
Tue 11/311:10 pm -
1 stop25h 26m
Deal found 9/8![LATAM Airlines logo]()
$775
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:32 am -
3 stops32h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$358
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/66:15 am -
1 stop18h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![LATAM Airlines logo]()
$368
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:57 am -
2 stops26h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![LATAM Airlines logo]()
$382
This Copa Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:30 pm -
1 stop27h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Copa Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:10 pm -
2 stops32h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Delta logo]()
$398
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:30 pm -
1 stop16h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Copa Airlines logo]()
$401
This LATAM Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1210:30 pm -
3 stops35h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![LATAM Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:15 am -
2 stops20h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$406
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:54 pm -
3 stops28h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:20 am -
1 stop18h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Delta logo]()
$423
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:15 am -
2 stops27h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![LATAM Airlines logo]()
$431
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $752 (Justfly.com) |
One-way from | $358 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $835 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 10/23
3:00 pm-10:55 pm
2 stops27h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$382
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 10/23
10:30 pm-6:10 am
1 stop27h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$395
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 10/16
10:30 pm-8:32 pm
1 stop18h 02m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$395
Quickest round-trip
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Mon 11/16
10:30 pm-8:15 pm
1 stop16h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$395
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Thu 2/4
7:15 am-9:00 am
2 stops20h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$398
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Mon 11/16
7:15 am-8:45 am
2 stops20h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$406
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sat 1/2
6:20 am-5:35 am
1 stop18h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$423
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 10/16
10:30 pm-3:00 pm
3 stops36h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$449
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Sat 11/7
6:15 am-7:30 am
2 stops20h 15m
Santiago Arturo Merino Benitez
Mon 12/7
11:10 pm-11:54 am
1 stop17h 44m
$818
San DiegoSantiago
SAN San Diego - SCL Santiago Arturo Merino Benitez
SANSCL
San Diego
Fri 1/1
6:15 am-6:40 am
1 stop19h 25m
Santiago Arturo Merino Benitez
Wed 1/27
11:55 pm-10:30 am
1 stop15h 35m
$825
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $695). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,476). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Airfare is typical for this route at the moment.
San Diego to Santiago flights typically cost between $739 and $867 in November.The cheapest round-trip price found within the last 5 days was $752 on LATAM Airlines (Nov 26-Dec 3).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 9, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andUnited Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
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San Diego and Santiago flights
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Top 4 airlines flying from San Diego to Santiago
Discover the top 4 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$555 | Average$734 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$563 | Average$857 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$642 | Average$905 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$671 | Average$969 | FlexibilityNo cancel fee | On-time71% |