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$308+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
dic 13 — dic 201
sab 12/13
sab 12/20
1 adult, Economy
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Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in August or October, booked 60 days in advance, depart on a Sunday or Saturday and return on a Friday

Find flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on novembre 13, 2025.

This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 12/28:25 amSAN - SCL
1 stop18h 35mAmerican Airlines
sab 12/611:15 pmSCL - SAN
1 stop20h 17mAmerican Airlines
Deal found 11/12$650
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 11/189:59 amSAN - SCL
1 stop15h 31mDelta
gio 11/275:25 pmSCL - SAN
2 stops20h 50mDelta
Deal found 11/11$664
This LATAM Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 12/2610:30 pmSAN - SCL
1 stop26h 40mLATAM Airlines
lun 1/1910:15 pmSCL - SAN
2 stops30h 33mLATAM Airlines
Deal found 11/13$668
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 11/258:40 pmSAN - SCL
2 stops31h 10mUnited Airlines
lun 12/110:45 pmSCL - SAN
1 stop24h 36mUnited Airlines
Deal found 11/10$669
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 12/79:37 amSAN - SCL
2 stops18h 18mAmerican Airlines
dom 12/1410:30 pmSCL - SAN
2 stops18h 27mAmerican Airlines
Deal found 11/11$673
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 11/215:50 pmSAN - SCL
1 stop34h 00mUnited Airlines
lun 12/110:45 pmSCL - SAN
1 stop22h 31mUnited Airlines
Deal found 11/12$674
This KAYAK deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 11/256:35 amSAN - SCL
2 stops19h 25mLATAM Airlines
mar 12/27:15 amSCL - SAN
3 stops31h 39mLATAM Airlines
Deal found 11/11$715
This Gurufare deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 12/1512:24 pmSAN - SCL
1 stop36h 46mLATAM Airlines
mar 1/139:30 pmSCL - SAN
1 stop17h 28mLATAM Airlines
Deal found 11/12$732
This Gurufare deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 12/136:15 amSAN - SCL
1 stop18h 55mLATAM Airlines
sab 12/2711:55 pmSCL - SAN
1 stop20h 38mLATAM Airlines
Deal found 11/11$733

Cheap flight deals from San Diego to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated novembre 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$650
(American Airlines)

One-way from

$308
(United Airlines)

Popular in

December

Cheapest in

August

Average price

$691
Provider with most accurate pricing for San Diego-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Santiago Arturo Merino Benitez flights.
Search Deals
From San Diego to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Diego to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembre 13, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

San Diego

Fly to

Santiago

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

mar 11/25

8:00 am-7:00 am

2 stops18h 00m

Santiago Arturo Merino Benitez

mar 12/2

11:10 pm-1:02 pm

1 stop18h 52m

$655

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

dom 12/28

6:15 am-6:10 am

1 stop18h 55m

Santiago Arturo Merino Benitez

lun 1/19

6:30 pm-9:58 am

2 stops20h 28m

$664

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

dom 12/7

6:15 am-6:10 am

1 stop18h 55m

Santiago Arturo Merino Benitez

dom 12/14

11:55 pm-3:23 pm

1 stop20h 28m

$664

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

mar 1/13

11:08 am-3:30 pm

2 stops23h 22m

Santiago Arturo Merino Benitez

lun 1/26

8:15 am-11:48 pm

2 stops20h 33m

$664

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

gio 12/11

11:02 am-8:50 am

2 stops16h 48m

Santiago Arturo Merino Benitez

gio 12/18

10:45 pm-5:34 pm

2 stops23h 49m

$669

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

gio 1/15

8:25 am-8:15 am

1 stop18h 50m

Santiago Arturo Merino Benitez

mar 1/20

10:30 pm-3:03 pm

2 stops21h 33m

$669

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

sab 2/28

10:30 pm-7:00 am

1 stop27h 30m

Santiago Arturo Merino Benitez

sab 3/7

6:30 pm-2:22 pm

2 stops24h 52m

$669

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

mer 12/10

1:53 pm-8:50 am

1 stop13h 57m

$308

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

lun 12/1

8:12 pm-8:21 pm

1 stop19h 09m

$310

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

lun 12/8

8:12 pm-11:41 pm

1 stop22h 29m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 12 results
1
2

Compare providers for flights from San Diego to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in November.
ProviderPrice AccuracyTrust Score*
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Santiago. Price data was last updated on November 7, 2025.

Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $484). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SCL?

Find hourly flight availability from San Diego to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated novembre 13, 2025.

When flying from San Diego to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the afternoon.

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated novembre 13, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,565 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,876 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Diego to Santiago?

    LATAM Airlines and Delta can get you from San Diego to Santiago in just under 18h. Your travel time can differ by up to 55m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Diego to Santiago round-trip?

    Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are LATAM Airlines and American Airlines, starting at $507 and $563 round-trip. You may be able to fly from San Diego to Santiago for 52% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Diego to Santiago that include hotel bookings?

    Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

  • Can I find deals for business class flights from San Diego to Santiago?

    Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $484). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Diego to Santiago

Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated novembre 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$453Average$742FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$507Average$963FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$563Average$1,053FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$574Average$822FlexibilityNo cancel feeOn-time69%
DeltaCheapest$802Average$1,002FlexibilityNo cancel feeOn-timeN/A

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