$395+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Jul 12 — Jul 191
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Santiago
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Best
Last-minute
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Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2026.
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:15 am
SAN
- SCL
1 stop19h 20m
LATAM Airlines
Sun 11/16:45 pm
SCL
- SAN
2 stops20h 45m
LATAM Airlines
Deal found 6/11![LATAM Airlines logo]()
$771
This KAYAK deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:15 am
SAN
- SCL
2 stops18h 10m
LATAM Airlines
Mon 11/304:10 am
SCL
- SAN
2 stops23h 45m
LATAM Airlines
Deal found 6/11![LATAM Airlines logo]()
$777
This Copa Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:00 pm
SAN
- SCL
1 stop25h 56m
Copa Airlines
Tue 10/63:57 am
SCL
- SAN
1 stop18h 33m
Copa Airlines
Deal found 6/9![Copa Airlines logo]()
$793
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:25 pm
SAN
- SCL
1 stop15h 25m
American Airlines
Sun 10/189:30 pm
SCL
- SAN
1 stop17h 55m
American Airlines
Deal found 6/8![American Airlines logo]()
$797
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:59 pm
SAN
- SCL
2 stops18h 06m
Delta
Mon 9/218:40 pm
SCL
- SAN
1 stop16h 56m
Delta
Deal found 6/9![Delta logo]()
$798
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:15 am
SAN
- SCL
1 stop22h 00m
Delta
Wed 10/77:15 am
SCL
- SAN
2 stops19h 40m
Delta
Deal found 6/12![Delta logo]()
$805
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2811:15 am
SAN
- SCL
2 stops17h 35m
American Airlines
Wed 10/79:30 pm
SCL
- SAN
1 stop17h 55m
American Airlines
Deal found 6/10![American Airlines logo]()
$810
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:00 pm
SAN
- SCL
1 stop25h 56m
Copa Airlines
Tue 10/63:15 am
SCL
- SAN
1 stop19h 15m
Copa Airlines
Deal found 6/10![Copa Airlines logo]()
$793
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am
SAN
- SCL
1 stop19h 50m
Delta
Tue 12/111:10 pm
SCL
- SAN
1 stop18h 58m
Delta
Deal found 6/11![Delta logo]()
$850
This Copa Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:00 pm
SAN
- SCL
1 stop21h 43m
Copa Airlines
Thu 8/2012:43 am
SCL
- SAN
1 stop20h 47m
Copa Airlines
Deal found 6/8![Copa Airlines logo]()
$883
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:42 pm
SAN
- SCL
1 stop15h 33m
Delta
Mon 9/218:40 pm
SCL
- SAN
1 stop16h 56m
Delta
Deal found 6/8![Delta logo]()
$889
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:50 am
SAN
- SCL
1 stop15h 45m
Delta
Sun 7/1210:55 pm
SCL
- SAN
1 stop24h 39m
Delta
Deal found 6/12![Delta logo]()
$895
This Copa Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:00 pm
SAN
- SCL
1 stop18h 32m
Copa Airlines
Sun 9/65:14 am
SCL
- SAN
1 stop17h 16m
Copa Airlines
Deal found 6/8![Copa Airlines logo]()
$895
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:00 am
SAN
- SCL
1 stop20h 15m
Delta
Sat 7/117:55 pm
SCL
- SAN
2 stops30h 00m
Delta
Deal found 6/12![Delta logo]()
$895
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:59 pm
SAN
- SCL
1 stop15h 16m
Delta
Wed 7/228:40 pm
SCL
- SAN
1 stop15h 46m
Delta
Deal found 6/12![Delta logo]()
$895
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:59 pm
SAN
- SCL
1 stop15h 16m
Delta
Tue 7/1410:55 pm
SCL
- SAN
1 stop24h 39m
Delta
Deal found 6/9![Delta logo]()
$895
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated June 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated June 12, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:15 am
SAN
- SCL
2 stops20h 45m
LATAM Airlines
Thu 6/254:30 pm
SCL
- SAN
2 stops30h 12m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$905
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:43 am
SAN
- SCL
2 stops28h 32m
Delta
Tue 7/147:55 pm
SCL
- SAN
2 stops22h 13m
Delta
Deal found 6/12![Delta logo]()
$895
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:20 am
SAN
- SCL
1 stop20h 05m
Delta
Sun 7/1210:55 pm
SCL
- SAN
2 stops23h 22m
Delta
Deal found 6/12![Delta logo]()
$900
This KAYAK deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:43 am
SAN
- SCL
3 stops23h 42m
LATAM Airlines
Wed 7/86:45 pm
SCL
- SAN
2 stops19h 49m
LATAM Airlines
Deal found 6/12![LATAM Airlines logo]()
$910
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:54 am
SAN
- SCL
1 stop15h 41m
Delta
Tue 7/1410:55 pm
SCL
- SAN
1 stop40h 00m
Delta
Deal found 6/8![Delta logo]()
$878
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/712:59 pm
SAN
- SCL
1 stop15h 16m
Delta
Mon 7/1311:00 pm
SCL
- SAN
2 stops21h 00m
Delta
Deal found 6/8![Delta logo]()
$889
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:58 pm
SAN
- SCL
1 stop30h 37m
Delta
Wed 7/158:40 pm
SCL
- SAN
1 stop23h 20m
Delta
Deal found 6/10![Delta logo]()
$901
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:00 pm
SAN
- SCL
1 stop18h 36m
Copa Airlines
Tue 7/1411:22 am
SCL
- SAN
1 stop34h 08m
Copa Airlines
Deal found 6/12![Copa Airlines logo]()
$909
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:30 pm
SAN
- SCL
1 stop29h 45m
Delta
Tue 7/1410:55 pm
SCL
- SAN
1 stop24h 39m
Delta
Deal found 6/8![Delta logo]()
$913
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1210:54 am
SAN
- SCL
1 stop15h 41m
Delta
Wed 7/158:40 pm
SCL
- SAN
1 stop19h 28m
Delta
Deal found 6/11![Delta logo]()
$907
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated June 12, 2026.
This Despegar deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/283:59 pm
SAN
- SCL
2 stops17h 06m
LATAM Airlines
Deal found 6/9![LATAM Airlines logo]()
$395
This FlightHub deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:30 pm
SAN
- SCL
2 stops28h 05m
LATAM Airlines
Deal found 6/7![LATAM Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:59 pm
SAN
- SCL
1 stop15h 16m
Delta
Deal found 6/11![Delta logo]()
$434
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:25 pm
SAN
- SCL
1 stop29h 50m
Delta
Deal found 6/9![Delta logo]()
$445
This Travelocity deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:43 am
SAN
- SCL
3 stops23h 42m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$450
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:30 pm
SAN
- SCL
1 stop29h 45m
Delta
Deal found 6/8![Delta logo]()
$454
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:41 am
SAN
- SCL
2 stops18h 19m
American Airlines
Deal found 6/11![American Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/159:06 pm
SAN
- SCL
3 stops43h 39m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$480
This Ovago deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:30 pm
SAN
- SCL
3 stops35h 55m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$506
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $771 (FlightHub) |
One-way from | $395 (Despegar) |
Popular in | August |
Cheapest in | September |
Average price | $765 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 9/28
10:00 pm-3:56 am
1 stop25h 56m
Santiago Arturo Merino Benitez
Tue 10/6
3:15 am-6:30 pm
1 stop19h 15m
$793
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 11/17
7:00 am-7:50 am
1 stop19h 50m
Santiago Arturo Merino Benitez
Tue 12/1
11:10 pm-1:08 pm
1 stop18h 58m
$850
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 8/14
10:00 pm-10:43 pm
1 stop21h 43m
Santiago Arturo Merino Benitez
Thu 8/20
12:43 am-6:30 pm
1 stop20h 47m
$883
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 9/16
12:42 pm-8:15 am
1 stop15h 33m
Santiago Arturo Merino Benitez
Mon 9/21
8:40 pm-9:36 am
1 stop16h 56m
$889
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 6/22
10:50 am-5:35 am
1 stop15h 45m
Santiago Arturo Merino Benitez
Sun 7/12
10:55 pm-8:34 pm
1 stop24h 39m
$895
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 9/2
10:00 pm-7:32 pm
1 stop18h 32m
Santiago Arturo Merino Benitez
Sun 9/6
5:14 am-6:30 pm
1 stop17h 16m
$895
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 6/22
8:00 am-7:15 am
1 stop20h 15m
Santiago Arturo Merino Benitez
Sat 7/11
7:55 pm-10:55 pm
2 stops30h 00m
$895
Quickest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 7/15
12:59 pm-7:15 am
1 stop15h 16m
Santiago Arturo Merino Benitez
Wed 7/22
8:40 pm-9:26 am
1 stop15h 46m
$895
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 7/7
12:59 pm-7:15 am
1 stop15h 16m
Santiago Arturo Merino Benitez
Tue 7/14
10:55 pm-8:34 pm
1 stop24h 39m
$895
Cheapest one-way
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sat 11/28
6:15 am-5:35 am
1 stop18h 20m
$422
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
How far ahead should I book a flight from San Diego to Santiago?
Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, September is the cheapest month in which you can book a flight from San Diego to Santiago (average of $631). Flying from San Diego to Santiago in August is currently the most expensive (average of $1,500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andUnited Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Santiago by cabin class
Find flights from San Diego to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Santiago flights
Browse other San Diego and Santiago flight options. Last updated on June 12, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 12, 2026.
Top 4 airlines flying from San Diego to Santiago
Discover the top 4 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$504 | Average$875 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$893 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$574 | Average$941 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$574 | Average$734 | FlexibilityNo cancel fee | On-time69% |