$344+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Aug 29 — Sep 51
Round-trip
1 adult, Economy
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Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:30 pm
SAN
- SCL
2 stops17h 15m
LATAM Airlines
Wed 9/3011:55 pm
SCL
- SAN
1 stop23h 18m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$716
This oojo deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:15 am
SAN
- SCL
2 stops18h 05m
LATAM Airlines
Sun 12/1311:55 pm
SCL
- SAN
1 stop20h 08m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$733
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:00 pm
SAN
- SCL
1 stop25h 56m
Copa Airlines
Tue 10/63:15 am
SCL
- SAN
1 stop19h 15m
Copa Airlines
Deal found 7/28![Copa Airlines logo]()
$743
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/202:00 pm
SAN
- SCL
1 stop14h 15m
Delta
Mon 9/2811:55 pm
SCL
- SAN
2 stops23h 31m
Delta
Deal found 7/27![Delta logo]()
$748
This LATAM Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:00 pm
SAN
- SCL
2 stops20h 00m
LATAM Airlines
Wed 10/78:50 am
SCL
- SAN
2 stops18h 52m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$757
This Bravofly deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Bravofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:54 am
SAN
- SCL
1 stop14h 41m
LATAM Airlines
Sat 9/195:10 am
SCL
- SAN
2 stops21h 24m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$759
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2810:54 am
SAN
- SCL
1 stop14h 41m
LATAM Airlines
Wed 10/711:55 pm
SCL
- SAN
1 stop14h 22m
LATAM Airlines
Deal found 7/26![LATAM Airlines logo]()
$760
This LATAM Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:20 am
SAN
- SCL
3 stops28h 05m
LATAM Airlines
Wed 9/305:10 am
SCL
- SAN
2 stops22h 37m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$762
This Justfly.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:15 am
SAN
- SCL
1 stop19h 20m
LATAM Airlines
Mon 9/2111:55 pm
SCL
- SAN
1 stop23h 18m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:32 pm
SAN
- SCL
1 stop15h 33m
American Airlines
Thu 9/38:50 pm
SCL
- SAN
1 stop28h 59m
American Airlines
Deal found 7/29![American Airlines logo]()
$769
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:00 pm
SAN
- SCL
1 stop18h 32m
Copa Airlines
Thu 9/173:14 am
SCL
- SAN
1 stop19h 15m
Copa Airlines
Deal found 7/28![Copa Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:26 am
SAN
- SCL
2 stops18h 34m
American Airlines
Mon 11/2310:15 pm
SCL
- SAN
2 stops22h 35m
American Airlines
Deal found 7/29![American Airlines logo]()
$760
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:30 pm
SAN
- SCL
2 stops29h 25m
Delta
Sun 8/238:40 pm
SCL
- SAN
1 stop15h 46m
Delta
Deal found 7/25![Delta logo]()
$815
This LATAM Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:00 pm
SAN
- SCL
2 stops23h 00m
LATAM Airlines
Mon 11/211:10 pm
SCL
- SAN
1 stop17h 03m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$835
This Copa Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:00 pm
SAN
- SCL
1 stop26h 46m
Copa Airlines
Fri 11/133:19 am
SCL
- SAN
1 stop18h 56m
Copa Airlines
Deal found 7/27![Copa Airlines logo]()
$743
This Copa Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:00 pm
SAN
- SCL
1 stop21h 39m
Copa Airlines
Tue 9/293:14 am
SCL
- SAN
1 stop19h 16m
Copa Airlines
Deal found 7/29![Copa Airlines logo]()
$743
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:20 am
SAN
- SCL
2 stops20h 40m
Delta
Fri 9/188:55 pm
SCL
- SAN
2 stops24h 10m
Delta
Deal found 7/28![Delta logo]()
$825
This Copa Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:00 pm
SAN
- SCL
1 stop26h 46m
Copa Airlines
Mon 11/235:07 am
SCL
- SAN
1 stop17h 08m
Copa Airlines
Deal found 7/29![Copa Airlines logo]()
$743
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:29 am
SAN
- SCL
1 stop18h 21m
Delta
Tue 12/111:10 pm
SCL
- SAN
1 stop16h 00m
Delta
Deal found 7/29![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:00 pm
SAN
- SCL
2 stops20h 00m
Delta
Tue 9/298:40 pm
SCL
- SAN
1 stop17h 05m
Delta
Deal found 7/27![Delta logo]()
$828
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 am
SAN
- SCL
1 stop19h 20m
Delta
Tue 10/68:40 pm
SCL
- SAN
1 stop18h 33m
Delta
Deal found 7/27![Delta logo]()
$828
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated July 30, 2026 and is based on user searches.
This SmartFares deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:00 pm
SAN
- SCL
1 stop21h 43m
Copa Airlines
Sun 8/2311:22 am
SCL
- SAN
1 stop34h 08m
Copa Airlines
Deal found 7/25![Copa Airlines logo]()
$812
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:30 pm
SAN
- SCL
2 stops29h 25m
Delta
Sun 8/238:40 pm
SCL
- SAN
1 stop15h 46m
Delta
Deal found 7/25![Delta logo]()
$815
This oojo deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/149:27 pm
SAN
- SCL
2 stops29h 08m
Multiple Airlines
Fri 8/2111:25 pm
SCL
- SAN
1 stop22h 54m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$806
This oojo deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:59 pm
SAN
- SCL
1 stop30h 36m
LATAM Airlines
Fri 8/2111:25 pm
SCL
- SAN
1 stop18h 45m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$810
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:15 am
SAN
- SCL
1 stop20h 20m
LATAM Airlines
Tue 8/255:40 am
SCL
- SAN
2 stops21h 14m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$783
This Copa Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:00 pm
SAN
- SCL
1 stop26h 00m
Copa Airlines
Sun 8/3012:43 am
SCL
- SAN
1 stop20h 47m
Copa Airlines
Deal found 7/27![Copa Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:20 am
SAN
- SCL
2 stops21h 45m
American Airlines
Mon 8/318:50 pm
SCL
- SAN
2 stops21h 36m
American Airlines
Deal found 7/27![American Airlines logo]()
$760
This oojo deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:15 am
SAN
- SCL
1 stop20h 20m
LATAM Airlines
Fri 9/48:30 am
SCL
- SAN
3 stops29h 50m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$819
This LATAM Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:15 am
SAN
- SCL
1 stop22h 00m
LATAM Airlines
Wed 9/26:45 pm
SCL
- SAN
2 stops23h 25m
LATAM Airlines
Deal found 7/28![LATAM Airlines logo]()
$807
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:32 pm
SAN
- SCL
1 stop15h 33m
American Airlines
Thu 9/38:50 pm
SCL
- SAN
1 stop28h 59m
American Airlines
Deal found 7/29![American Airlines logo]()
$769
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:59 pm
SAN
- SCL
3 stops49h 51m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$344
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:55 am
SAN
- SCL
1 stop15h 40m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:48 pm
SAN
- SCL
3 stops49h 50m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:25 am
SAN
- SCL
3 stops43h 49m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:45 pm
SAN
- SCL
3 stops51h 58m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$355
This Justfly.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:57 am
SAN
- SCL
1 stop14h 38m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:54 pm
SAN
- SCL
3 stops49h 45m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$359
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:19 am
SAN
- SCL
1 stop20h 16m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:45 pm
SAN
- SCL
3 stops42h 50m
Multiple Airlines
Deal found 7/29![Multiple Airlines logo]()
$367
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
SAN
- SCL
1 stop20h 20m
LATAM Airlines
Deal found 7/29![LATAM Airlines logo]()
$368
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $716 (FlightHub) |
One-way from | $344 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $1,029 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 9/11
10:00 pm-8:32 pm
1 stop18h 32m
Santiago Arturo Merino Benitez
Thu 9/17
3:14 am-6:29 pm
1 stop19h 15m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sat 11/7
10:00 pm-5:46 am
1 stop26h 46m
Santiago Arturo Merino Benitez
Fri 11/13
3:19 am-5:15 pm
1 stop18h 56m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 9/9
10:00 pm-11:39 pm
1 stop21h 39m
Santiago Arturo Merino Benitez
Tue 9/29
3:14 am-6:30 pm
1 stop19h 16m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 11/9
10:00 pm-5:46 am
1 stop26h 46m
Santiago Arturo Merino Benitez
Mon 11/23
5:07 am-5:15 pm
1 stop17h 08m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 11/9
9:26 am-9:00 am
2 stops18h 34m
Santiago Arturo Merino Benitez
Mon 11/23
10:15 pm-3:50 pm
2 stops22h 35m
$760
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 8/10
9:30 pm-5:55 am
2 stops29h 25m
Santiago Arturo Merino Benitez
Sun 8/23
8:40 pm-9:26 am
1 stop15h 46m
$815
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 9/11
6:20 am-7:00 am
2 stops20h 40m
Santiago Arturo Merino Benitez
Fri 9/18
8:55 pm-5:05 pm
2 stops24h 10m
$825
Quickest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 11/17
7:29 am-6:50 am
1 stop18h 21m
Santiago Arturo Merino Benitez
Tue 12/1
11:10 pm-10:10 am
1 stop16h 00m
$825
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sat 9/26
3:00 pm-3:00 pm
2 stops20h 00m
Santiago Arturo Merino Benitez
Tue 9/29
8:40 pm-9:45 am
1 stop17h 05m
$828
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Thu 10/1
6:15 am-5:35 am
1 stop19h 20m
Santiago Arturo Merino Benitez
Tue 10/6
8:40 pm-11:13 am
1 stop18h 33m
$828
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
How far ahead should I book a flight from San Diego to Santiago?
Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, September is the cheapest month in which you can book a flight from San Diego to Santiago (average of $573). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Airfare is below average for this route at the moment.
San Diego to Santiago flights typically cost between $727 and $1,500 in September.The cheapest round-trip price found within the last 5 days was $716 on LATAM Airlines (Sep 9-Sep 30).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 30, 2026.
See what other customers who have flown with Delta,LATAM Airlines, andUnited Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Santiago flight routes
Alternative routes for San Diego to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Santiago by cabin class
Find flights from San Diego to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Santiago flights
Browse other San Diego and Santiago flight options. Last updated on July 30, 2026.
Other flights from San Diego
Browse through other flights departing from San Diego. Flights are based on user searches made on Cheapflights and were last updated on July 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 30, 2026.
Top 4 airlines flying from San Diego to Santiago
Discover the top 4 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$504 | Average$739 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$514 | Average$734 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$563 | Average$955 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$642 | Average$914 | FlexibilityNo cancel fee | On-timeN/A |