$469+ Cheap flights from Los Angeles (LAX) to La Serena (LSC)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Los Angeles to La Serena with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Los Angeles to La Serena
Cheapest flights from Los Angeles to La SerenaExplore the most affordable flight options available from Los Angeles to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Los Angeles to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Best flights from Los Angeles to La SerenaDiscover carefully curated flight deals from Los Angeles to La Serena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Los Angeles to La Serena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
One-way flights from Los Angeles to La SerenaSearch for one-way flight options from Los Angeles to La Serena. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Los Angeles to La Serena. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from Los Angeles to La Serena
Discover tips and strategies to find the most affordable flight options for your journey from Los Angeles (LAX) to La Serena (LSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $893 (LATAM Airlines) |
One-way from | $469 (Kiwi.com) |
Cheapflights Fare Finder
Use the filters below to find and compare flights from Los Angeles to La Serena that are best for you.
Fly from
Fly to
Route
Depart
Return
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Wed 10/28
10:04 pm-9:32 am
3 stops31h 28m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Fri 10/23
10:04 pm-10:35 am
3 stops32h 31m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Mon 10/26
11:10 am-3:37 pm
2 stops24h 27m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Sun 10/25
2:55 pm-12:30 pm
1 stop17h 35m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Tue 10/27
9:05 am-12:39 pm
2 stops23h 34m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Thu 10/29
2:55 pm-3:31 pm
1 stop20h 36m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Mon 12/7
10:10 am-6:07 pm
2 stops26h 57m
La Serena La Florida
Thu 12/10
6:37 pm-6:45 am
2 stops17h 08m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Wed 11/11
10:10 am-4:40 pm
2 stops25h 30m
La Serena La Florida
Thu 11/19
5:20 pm-6:15 am
1 stop17h 55m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Tue 10/27
11:10 am-6:31 pm
3 stops27h 21m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
Los AngelesLa Serena
LAX Los Angeles Los Angeles - LSC La Serena La Florida
LAXLSC
Los Angeles Los Angeles
Thu 10/29
2:55 pm-10:47 am
1 stop15h 52m
La Serena La Florida
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
- Most accurate provider: When it comes to deals on Los Angeles-La Serena flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Los Angeles-La Serena flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Los Angeles-La Serena flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Los Angeles-La Serena flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Los Angeles-La Serena flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Los Angeles to La Serena
Have a flexible travel schedule? Discover the best time to fly to La Serena from Los Angeles with our price prediction graph.
Reviews of airlines servicing La Serena
Get insights into the airlines that provide service to La Serena. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Serena. Reviews last updated September 14, 2026.
Get a feel of what it's like to fly with LATAM Airlines from Los Angeles to La Serena by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
Comfort
Overall
Food
Boarding
Entertainment
Reviews
Noah,Aug 2026
JFK - GRU
Crew
Comfort
Overall
Food
Boarding
Entertainment
Reviews
Noah,Aug 2026
JFK - GRU
Related info for your journey
Find useful and relevant information for your journey from Los Angeles to La Serena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Los Angeles to La Serena
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to La Serena by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Los Angeles to La Serena by cabin class
Find flights from Los Angeles to La Serena, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Los Angeles and La Serena flights
Browse other Los Angeles and La Serena flight options. Last updated on September 14, 2026.
Other flights from Los Angeles
Browse through other flights departing from Los Angeles. Flights are based on user searches made on Cheapflights and were last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Los Angeles to La Serena
Discover the top airline that operate flights from Los Angeles to La Serena. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$958 | Average$1,034 | FlexibilityNo cancel fee | On-time81% |