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La Serena

$444+ Cheap flights from Los Angeles (LAX) to La Serena (LSC)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — LSC
May 30 — Jun 61
Sat 5/30
Sat 6/6
1 adult, Economy
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Cheap flight deals from Los Angeles to La Serena

Cheapest flights from Los Angeles to La Serena
Explore the most affordable flight options available from Los Angeles to La Serena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1111:35 am
LAX
-
LSC
2 stops20h 13m
LATAM Airlines
Wed 5/1310:00 am
LSC
-
LAX
1 stop24h 45m
LATAM Airlines
Deal found 4/25$848
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:55 pm
LAX
-
LSC
1 stop15h 31m
Multiple Airlines
Thu 9/245:49 pm
LSC
-
LAX
1 stop17h 56m
Multiple Airlines
Deal found 4/29$976
This oojo deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:35 am
LAX
-
LSC
2 stops17h 40m
LATAM Airlines
Thu 9/244:30 pm
LSC
-
LAX
1 stop19h 15m
LATAM Airlines
Deal found 4/29$987
This LATAM Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2910:35 am
LAX
-
LSC
2 stops24h 48m
LATAM Airlines
Thu 12/36:44 pm
LSC
-
LAX
1 stop17h 01m
LATAM Airlines
Deal found 4/29$1,134

Find flight deals from Los Angeles to La Serena

Discover tips and strategies to find the most affordable flight options for your journey from Los Angeles (LAX) to La Serena (LSC). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$848
(LATAM Airlines)

One-way from

$444
(oojo)
Provider with most accurate pricing for Los Angeles-La Serena La Florida flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-La Serena La Florida flights.
Search Deals
From Los Angeles to La Serena La Florida
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One-way flight from Los Angeles to La Serena La Florida
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Los Angeles to La Serena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Los Angeles to La Serena that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles

Mon 5/11

11:35 am-10:48 am

2 stops20h 13m

La Serena La Florida

Wed 5/13

10:00 am-7:45 am

1 stop24h 45m

$848
Quickest round-trip

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles

Tue 9/8

11:35 am-9:15 am

2 stops17h 40m

La Serena La Florida

Thu 9/24

3:38 pm-7:45 am

2 stops20h 07m

$1,001

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles

Tue 9/8

11:35 am-12:15 pm

2 stops20h 40m

La Serena La Florida

Thu 9/24

10:00 am-12:25 pm

3 stops30h 25m

$1,145
Cheapest one-way
Quickest one-way

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles

Mon 5/4

11:35 am-10:48 am

2 stops20h 13m

$444

Los AngelesLa Serena

LAX - LSC

LAXLSC

Los Angeles

Mon 5/4

11:35 am-4:08 pm

3 stops25h 33m

$471

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Los Angeles-La Serena flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Los Angeles-La Serena flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Los Angeles-La Serena flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Los Angeles-La Serena flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Los Angeles-La Serena flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Los Angeles to La Serena

Have a flexible travel schedule? Discover the best time to fly to La Serena from Los Angeles with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Los Angeles to La Serena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Los Angeles to La Serena?

    Airlines like LATAM Airlines fly from Los Angeles to La Serena in about 20h 13m. The time it takes to get you to your destination can typically vary by up to . Los Angeles and La Serena are separated by a distance of 5377 mi.

  • Can I find deals for flights from Los Angeles to La Serena that include hotel bookings?

    Yes. In addition to deals on Los Angeles to La Serena flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Los Angeles to La Serena?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Los Angeles to La Serena.

  • Can I find deals for business class flights from Los Angeles to La Serena?

    Yes. Cheapflights offers flight deals from Los Angeles to La Serena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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