What are the cheapest airlines flying from Santiago to San Diego round-trip?

Our cheapest airline available from Santiago to San Diego is Copa Airlines. Our recent data shows that you can find tickets from as low as $502 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $793 and $795 round-trip. Copa Airlines is currently priced 45% below the average price you’ll pay for this route.

What is the cheapest day to fly from Santiago to San Diego?

Travelers seeking maximum savings on their Santiago to San Diego flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What is the cheapest day to fly round-trip from Santiago to San Diego?

Travelers have found that booking a Thursday departure is the best way to save up to 90% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Santiago to San Diego?

To save on the cost of your flight from Santiago to San Diego, book at least 9 days before your planned departure. Booking around this time can save you about 11% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $742 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $825.

What is the cheapest month to fly from Santiago to San Diego?

Due to multiple factors, expect to potentially pay more when booking in April. For low rates, August can be a great choice for travel to San Diego. Flights to San Diego from Santiago in August are about $922 on average during August, but can be found for as low as $487.

What is the cheapest time of day to fly from SCL to SAN?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to San Diego as you normally would.

Can I find deals for flights from Santiago to San Diego that include hotel bookings?

Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to San Diego?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

Can I find deals for business class flights from Santiago to San Diego?

Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$310+ Flights from Santiago to San Diego

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1. Tell us where you want to go

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3. Compare prices and book

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 76 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Round-trip from	$502 (Copa Airlines)
One-way from	$310 (Copa Airlines)
Popular in	April
Cheapest in	August
Average price	$863

From Santiago Arturo Merino Benitez to San Diego

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One-way flight from Santiago Arturo Merino Benitez to San Diego

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Highest demand for flights based on searches. 15% potential increase in price ($164 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($30 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Wed 9/245:11 amSCL - SAN

1 stop16h 39mCopa Airlines

Wed 10/89:12 pmSAN - SCL

1 stop22h 28mCopa Airlines

Deal found 6/30

$502

Thu 8/149:45 amSCL - SAN

1 stop37h 33mMultiple Airlines

Thu 8/219:00 amSAN - SCL

1 stop18h 45mMultiple Airlines

Deal found 6/30

$715

Sat 11/111:55 pmSCL - SAN

1 stop24h 01mLATAM Airlines

Thu 11/1311:00 amSAN - SCL

1 stop15h 00mLATAM Airlines

Deal found 6/30

$793

Wed 12/1011:40 pmSCL - SAN

1 stop26h 09mDelta

Tue 1/610:00 amSAN - SCL

1 stop14h 35mDelta

Deal found 6/30

$795

Sat 11/110:45 pmSCL - SAN

2 stops21h 15mUnited Airlines

Thu 11/138:00 amSAN - SCL

1 stop19h 50mUnited Airlines

Deal found 6/30

$802

Best flights from Santiago to San Diego
Discover carefully curated flight deals from Santiago to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 1, 2025.

Wed 9/245:11 amSCL - SAN

1 stop16h 39mCopa Airlines

Wed 10/89:12 pmSAN - SCL

1 stop22h 28mCopa Airlines

Deal found 6/30

$502

Thu 8/149:45 amSCL - SAN

1 stop37h 33mMultiple Airlines

Thu 8/219:00 amSAN - SCL

1 stop18h 45mMultiple Airlines

Deal found 6/30

$715

Sat 11/111:55 pmSCL - SAN

1 stop24h 01mLATAM Airlines

Thu 11/1311:00 amSAN - SCL

1 stop15h 00mLATAM Airlines

Deal found 6/30

$793

Wed 12/1011:40 pmSCL - SAN

1 stop26h 09mDelta

Tue 1/610:00 amSAN - SCL

1 stop14h 35mDelta

Deal found 6/30

$795

Sat 11/110:45 pmSCL - SAN

2 stops21h 15mUnited Airlines

Thu 11/138:00 amSAN - SCL

1 stop19h 50mUnited Airlines

Deal found 6/30

$802

Mon 8/119:55 pmSCL - SAN

2 stops20h 30mAmerican Airlines

Mon 8/188:18 amSAN - SCL

2 stops19h 37mAmerican Airlines

Deal found 6/29

$946

Last-minute flights from Santiago to San Diego
Discover last-minute flight deals from Santiago to San Diego. Data last updated July 1, 2025 and is based on user searches.

Sun 7/64:10 amSCL - SAN

1 stop16h 34mMultiple Airlines

Thu 7/2411:15 amSAN - SCL

2 stops40h 25mMultiple Airlines

Deal found 7/1

$966

Sun 7/610:55 pmSCL - SAN

1 stop27h 47mDelta

Thu 7/249:59 amSAN - SCL

1 stop17h 01mDelta

Deal found 6/29

$1,230

Tue 7/82:23 amSCL - SAN

1 stop18h 21mCopa Airlines

Wed 7/309:03 pmSAN - SCL

1 stop19h 21mCopa Airlines

Deal found 6/29

$867

Wed 7/911:05 pmSCL - SAN

2 stops21h 55mLATAM Airlines

Wed 7/309:59 amSAN - SCL

1 stop17h 01mLATAM Airlines

Deal found 6/30

$1,104

Wed 7/99:50 pmSCL - SAN

2 stops20h 49mAmerican Airlines

Wed 7/307:12 amSAN - SCL

2 stops20h 53mAmerican Airlines

Deal found 6/29

$1,136

Wed 7/3010:45 pmSCL - SAN

1 stop19h 34mLATAM Airlines

Tue 8/126:20 amSAN - SCL

1 stop20h 40mLATAM Airlines

Deal found 6/30

$961

Thu 7/312:26 amSCL - SAN

1 stop18h 18mCopa Airlines

Sun 8/109:03 pmSAN - SCL

1 stop22h 41mCopa Airlines

Deal found 6/30

$671

Thu 7/312:26 amSCL - SAN

1 stop18h 18mMultiple Airlines

Sat 8/161:17 pmSAN - SCL

3 stops34h 18mMultiple Airlines

Deal found 7/1

$944

One-way flights from Santiago to San Diego
Search for one-way flight options from Santiago to San Diego. Find affordable one-way fares based on user searches. Data last updated July 1, 2025.

Fri 8/154:11 amSCL - SAN

1 stop16h 33mCopa Airlines

Deal found 7/1

$310

Tue 8/264:11 amSCL - SAN

2 stops19h 18mMultiple Airlines

Deal found 6/30

$414

Fri 8/152:30 pmSCL - SAN

3 stops24h 58mLATAM Airlines

Deal found 7/1

$1,821

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 9/24

5:11 am-5:50 pm

1 stop16h 39m

San Diego

Wed 10/8

9:12 pm-11:40 pm

1 stop22h 28m

$502

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 8/14

9:45 am-8:18 pm

1 stop37h 33m

San Diego

Thu 8/21

9:00 am-6:45 am

1 stop18h 45m

$715

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/1

11:55 pm-7:56 pm

1 stop24h 01m

San Diego

Thu 11/13

11:00 am-7:00 am

1 stop15h 00m

$793

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 12/10

11:40 pm-8:49 pm

1 stop26h 09m

San Diego

Tue 1/6

10:00 am-5:35 am

1 stop14h 35m

$795

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/1

10:45 pm-4:00 pm

2 stops21h 15m

San Diego

Thu 11/13

8:00 am-8:50 am

1 stop19h 50m

$802

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/11

9:55 pm-3:25 pm

2 stops20h 30m

San Diego

Mon 8/18

8:18 am-6:55 am

2 stops19h 37m

$946

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 8/15

4:11 am-5:44 pm

1 stop16h 33m

$310

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 8/26

4:11 am-8:29 pm

2 stops19h 18m

$414

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 8/15

2:30 pm-12:28 pm

3 stops24h 58m

$1,821

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,974 reviews

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

LATAM Airlines

7.5

Good

1,805 reviews

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.5

Good

1,465 reviews

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,858 reviews

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,974 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Santiago to San Diego round-trip?
Our cheapest airline available from Santiago to San Diego is Copa Airlines. Our recent data shows that you can find tickets from as low as $502 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $793 and $795 round-trip. Copa Airlines is currently priced 45% below the average price you’ll pay for this route.
Can I find deals for flights from Santiago to San Diego that include hotel bookings?
Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to San Diego?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.
Can I find deals for business class flights from Santiago to San Diego?
Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to San Diego?
Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to San Diego

Top 2 airlines flying from Santiago to San Diego

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$702	Average$917	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$803	Average$933	FlexibilityNo cancel fee	On-time81%

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$310+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to San Diego with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 76 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San DiegoExplore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Diego. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Santiago to San Diego?

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santiago to San Diego round-trip?

Can I find deals for flights from Santiago to San Diego that include hotel bookings?

How can I find direct flights from Santiago to San Diego?

Can I find deals for business class flights from Santiago to San Diego?

What is the cheapest month to book a flight from Santiago to San Diego?

Traveling to a place near Santiago?

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Alternative routes for Santiago to San Diego

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Top 2 airlines flying from Santiago to San Diego

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Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.