$369+ Cheap flights from Santiago (SCL) to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Find cheap flights from Santiago to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santiago to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santiago to San DiegoExplore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:50 pm -
2 stops21h 35m
Sun 11/810:25 pm -
1 stop28h 15m
Deal found 10/18![Delta logo]()
$657
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:55 pm -
2 stops20h 45m
Wed 11/116:20 am -
2 stops20h 10m
Deal found 10/18![LATAM Airlines logo]()
$666
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:26 am -
1 stop20h 49m
Sat 12/510:30 pm -
1 stop24h 13m
Deal found 10/18![Copa Airlines logo]()
$678
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:10 pm -
1 stop22h 23m
Tue 12/18:00 am -
1 stop18h 40m
Deal found 10/18![Delta logo]()
$682
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:10 pm -
2 stops25h 04m
Sun 11/810:25 pm -
2 stops28h 05m
Deal found 10/18![LATAM Airlines logo]()
$684
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:13 am -
2 stops30h 36m
Sun 12/68:00 am -
1 stop17h 40m
Deal found 10/18![LATAM Airlines logo]()
$691
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:48 am -
2 stops27h 16m
Tue 12/18:00 am -
2 stops29h 00m
Deal found 10/18![LATAM Airlines logo]()
$692
This LATAM Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:55 pm -
2 stops20h 54m
Mon 12/76:20 am -
1 stop20h 20m
Deal found 10/17![LATAM Airlines logo]()
$693
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:13 am -
2 stops30h 36m
Wed 12/210:30 pm -
2 stops27h 30m
Deal found 10/18![LATAM Airlines logo]()
$696
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:26 am -
1 stop20h 49m
Sat 11/1410:30 pm -
1 stop26h 16m
Deal found 10/20![Copa Airlines logo]()
$703
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:50 pm -
2 stops23h 05m
Sat 11/1410:30 pm -
1 stop28h 10m
Deal found 10/19![Delta logo]()
$707
Best flights from Santiago to San DiegoDiscover carefully curated flight deals from Santiago to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Santiago to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:50 pm -
2 stops23h 05m
Sat 11/1410:30 pm -
1 stop28h 10m
Deal found 10/16![Delta logo]()
$657
This Copa Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:07 am -
1 stop17h 08m
Sun 12/610:30 pm -
1 stop16h 41m
Deal found 10/17![Copa Airlines logo]()
$678
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:45 pm -
2 stops17h 46m
Sat 11/146:26 pm -
2 stops33h 24m
Deal found 10/16![United Airlines logo]()
$707
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:50 pm -
2 stops21h 35m
Sun 11/810:25 pm -
1 stop28h 15m
Deal found 10/17![Delta logo]()
$657
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:07 am -
1 stop17h 08m
Sun 11/810:30 pm -
1 stop23h 18m
Deal found 10/20![Copa Airlines logo]()
$703
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:45 pm -
1 stop24h 08m
Sat 12/56:23 pm -
2 stops33h 27m
Deal found 10/18![United Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:45 pm -
1 stop24h 08m
Sun 12/611:25 am -
1 stop16h 25m
Deal found 10/19![United Airlines logo]()
$708
Last-minute flights from Santiago to San DiegoDiscover last-minute flight deals from Santiago to San Diego. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to San Diego. Data last updated October 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:50 pm -
2 stops21h 35m
Sun 11/810:25 pm -
1 stop28h 15m
Deal found 10/18![Delta logo]()
$657
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:10 pm -
2 stops25h 04m
Sun 11/810:25 pm -
2 stops28h 05m
Deal found 10/18![LATAM Airlines logo]()
$684
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:10 pm -
1 stop25h 26m
Sat 11/1410:30 pm -
1 stop28h 10m
Deal found 10/20![Delta logo]()
$707
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:26 am -
1 stop20h 49m
Sat 11/1410:30 pm -
1 stop26h 16m
Deal found 10/20![Copa Airlines logo]()
$703
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:55 pm -
2 stops20h 45m
Wed 11/116:20 am -
2 stops20h 10m
Deal found 10/18![LATAM Airlines logo]()
$666
This LATAM Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:55 pm -
2 stops20h 54m
Mon 12/710:30 pm -
2 stops28h 00m
Deal found 10/17![LATAM Airlines logo]()
$693
This Copa Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:26 am -
1 stop20h 49m
Sat 12/510:30 pm -
1 stop24h 13m
Deal found 10/18![Copa Airlines logo]()
$678
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:48 am -
2 stops27h 16m
Tue 12/18:00 am -
2 stops29h 00m
Deal found 10/18![LATAM Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:10 pm -
1 stop22h 23m
Tue 12/18:00 am -
1 stop18h 40m
Deal found 10/18![Delta logo]()
$682
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:13 am -
2 stops30h 36m
Sun 12/68:00 am -
1 stop17h 40m
Deal found 10/18![LATAM Airlines logo]()
$691
This LATAM Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:13 am -
2 stops30h 36m
Wed 12/210:30 pm -
2 stops27h 30m
Deal found 10/18![LATAM Airlines logo]()
$696
One-way flights from Santiago to San DiegoSearch for one-way flight options from Santiago to San Diego. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
Search for one-way flight options from Santiago to San Diego. Find affordable one-way fares based on user searches. Data last updated October 21, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:26 am -
1 stop20h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Copa Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:10 pm -
1 stop27h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$373
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:45 pm -
2 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:40 am -
2 stops19h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Delta logo]()
$378
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2610:45 pm -
2 stops48h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$379
This eDestinos deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/287:40 am -
2 stops20h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![LATAM Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:45 pm -
2 stops17h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$382
This Expedia deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:35 am -
3 stops40h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/17![LATAM Airlines logo]()
$403
This FlightHub deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/258:13 am -
2 stops30h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![LATAM Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:45 pm -
3 stops54h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2610:25 pm -
1 stop18h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![American Airlines logo]()
$428
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/199:45 am -
2 stops29h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$448
Find flight deals from Santiago to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $657 (Delta) |
One-way from | $369 (Copa Airlines) |
Popular in | January |
Cheapest in | April |
Average price | $809 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Thu 11/5
1:26 am-5:15 pm
1 stop20h 49m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$369
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Tue 2/2
11:10 pm-1:08 pm
1 stop18h 58m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$369
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Sat 3/6
1:16 am-5:32 pm
1 stop21h 16m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$369
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Wed 12/2
11:10 pm-9:19 pm
1 stop27h 09m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$373
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Thu 1/28
11:00 pm-11:03 pm
1 stop29h 03m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$373
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Mon 1/25
9:50 pm-11:03 pm
1 stop30h 13m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$373
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Tue 12/1
8:40 am-10:56 pm
2 stops19h 16m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$378
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Sun 3/7
10:45 pm-7:47 pm
3 stops50h 02m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$379
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Thu 2/4
5:55 pm-5:11 pm
2 stops28h 16m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$380
Quickest round-trip
SantiagoSan Diego
SCL Santiago Arturo Merino Benitez - SAN San Diego
SCLSAN
Santiago Arturo Merino Benitez
Tue 12/1
9:45 am-11:38 pm
2 stops18h 53m
San Diego
Wed 12/31
12:00 am-5:00 am
Nonstop0h 00m
$382
Showing 1-10 of 18 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santiago-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santiago-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santiago to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
SCL-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to San Diego
How far ahead should I book a flight from Santiago to San Diego?
Booking 68 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santiago to San Diego?
Currently, April is the cheapest month in which you can book a flight from Santiago to San Diego (average of $638). Flying from Santiago to San Diego in January is currently the most expensive (average of $1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to San Diego?
Airfare is typical for this route at the moment.
Santiago to San Diego flights typically cost between $634 and $982 in November.The cheapest round-trip price found within the last 5 days was $657 on Delta (Nov 2-Nov 8).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 21, 2026.
Get a feel of what it's like to fly with LATAM Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.4
Comfort
7.3
Entertainment
7.0
Crew
8.0
Boarding
7.5
Food
6.7
Reviews
1 / 20
2.0
MediocrePedro,Oct 2026
MDW - ATL
Overall
7.4
Comfort
7.3
Entertainment
7.0
Crew
8.0
Boarding
7.5
Food
6.7
Reviews
1 / 20
2.0
MediocrePedro,Oct 2026
MDW - ATL
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Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
San Ysidro
Poway
Coronado
La Mesa
Julian
Santee
Lemon Grove
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Santiago and San Diego flights
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Top airline flying from Santiago to San Diego
Discover the top airline that operate flights from Santiago to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$560 | Average$1,220 | FlexibilityNo cancel fee | On-time81% |