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$399+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:25 pm
SCL
-
SAN
1 stop18h 44m
LATAM Airlines
Mon 8/1710:00 am
SAN
-
SCL
1 stop16h 35m
LATAM Airlines
Deal found 4/23$570
This LATAM Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:25 pm
SCL
-
SAN
1 stop14h 02m
LATAM Airlines
Sun 8/306:15 am
SAN
-
SCL
1 stop20h 20m
LATAM Airlines
Deal found 4/21$600
This Copa Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/244:14 am
SCL
-
SAN
1 stop17h 16m
Copa Airlines
Sun 8/308:58 pm
SAN
-
SCL
1 stop23h 28m
Copa Airlines
Deal found 4/19$605
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:00 pm
SCL
-
SAN
2 stops21h 00m
Delta
Mon 8/176:20 am
SAN
-
SCL
2 stops21h 35m
Delta
Deal found 4/19$608
This Copa Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:09 am
SCL
-
SAN
1 stop17h 21m
Copa Airlines
Sun 6/1410:00 pm
SAN
-
SCL
1 stop21h 43m
Copa Airlines
Deal found 4/23$609
This eDestinos deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:25 pm
SCL
-
SAN
1 stop18h 32m
LATAM Airlines
Wed 6/1010:50 am
SAN
-
SCL
1 stop15h 45m
LATAM Airlines
Deal found 4/19$610
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:55 pm
SCL
-
SAN
2 stops23h 28m
Delta
Sat 6/1310:30 pm
SAN
-
SCL
1 stop29h 45m
Delta
Deal found 4/23$612
This LATAM Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:25 pm
SCL
-
SAN
1 stop18h 46m
LATAM Airlines
Sun 6/146:15 am
SAN
-
SCL
2 stops20h 20m
LATAM Airlines
Deal found 4/23$613
This eDestinos deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:25 pm
SCL
-
SAN
1 stop18h 32m
LATAM Airlines
Mon 6/1510:50 am
SAN
-
SCL
1 stop15h 45m
LATAM Airlines
Deal found 4/21$615

Find flight deals from Santiago to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$592
(FlightHub)

One-way from

$399
(Kiwi.com)

Popular in

June

Cheapest in

August

Average price

$722
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Diego flights.
Search Deals
From Santiago Arturo Merino Benitez to San Diego
Search Deals
One-way flight from Santiago Arturo Merino Benitez to San Diego
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sun 8/23

12:06 am-6:30 pm

1 stop21h 24m

San Diego

Sun 8/30

8:58 pm-10:43 pm

1 stop22h 45m

$605
Quickest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/29

4:09 am-6:30 pm

1 stop17h 21m

San Diego

Sun 6/14

10:00 pm-10:43 pm

1 stop21h 43m

$609

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 6/5

10:55 pm-7:23 pm

2 stops23h 28m

San Diego

Sat 6/13

10:30 pm-7:15 am

1 stop29h 45m

$612

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/3

11:00 pm-5:00 pm

2 stops21h 00m

San Diego

Mon 8/17

6:20 am-6:55 am

2 stops21h 35m

$612

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/22

10:55 pm-6:01 pm

2 stops22h 06m

San Diego

Sun 6/7

9:38 pm-7:15 am

1 stop30h 37m

$612

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 5/29

10:30 am-7:23 pm

2 stops35h 53m

San Diego

Sun 6/14

10:30 pm-6:55 am

2 stops29h 25m

$626

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 6/5

8:40 pm-9:43 am

1 stop16h 03m

San Diego

Fri 6/12

10:30 pm-7:15 am

1 stop29h 45m

$638

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sun 5/31

11:25 pm-2:57 pm

1 stop18h 32m

San Diego

Sat 6/20

10:30 pm-7:15 am

1 stop29h 45m

$638
Cheapest one-way

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 5/4

3:20 pm-11:12 pm

3 stops34h 52m

$449
Quickest one-way

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 5/23

11:25 pm-2:57 pm

1 stop18h 32m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Santiago to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Diego in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Booking 36 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $502). Flying from Santiago to San Diego in June is currently the most expensive (average of $1,123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to San Diego?

    Departing from Santiago to San Diego will take you 17h 16m. Airlines will cover a distance of 5471 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Santiago to San Diego one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $332. Delta flights start at $347 while deals on American Airlines start at $351 one-way.

  • Can I find deals for flights from Santiago to San Diego that include hotel bookings?

    Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

  • Can I find deals for business class flights from Santiago to San Diego?

    Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $502). Flying from Santiago to San Diego in June is currently the most expensive (average of $1,123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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