What are the cheapest airlines flying from Santiago to San Diego round-trip?

Our cheapest airline available from Santiago to San Diego is Copa Airlines. Our recent data shows that you can find tickets from as low as $454 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $678 and $687 round-trip. Copa Airlines is currently priced 50% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Santiago to San Diego one-way?

To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $258. Delta flights start at $573 while deals on United Airlines start at $581 one-way.

What is the cheapest day to fly from Santiago to San Diego?

Travelers seeking maximum savings on their Santiago to San Diego flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What is the cheapest day to fly round-trip from Santiago to San Diego?

Travelers have found that booking a Thursday departure is the best way to save up to 90% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from Santiago to San Diego?

To save on the cost of your flight from Santiago to San Diego, book at least 9 days before your planned departure. Booking around this time can save you about 11% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $742 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $825.

What is the cheapest month to fly from Santiago to San Diego?

Due to multiple factors, expect to potentially pay more when booking in April. For low rates, August can be a great choice for travel to San Diego. Flights to San Diego from Santiago in August are about $922 on average during August, but can be found for as low as $487.

What is the cheapest time of day to fly from SCL to SAN?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to San Diego as you normally would.

Can I find deals for flights from Santiago to San Diego that include hotel bookings?

Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to San Diego?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

Can I find deals for business class flights from Santiago to San Diego?

Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$258+ Flights from Santiago to San Diego

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1. Tell us where you want to go

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2. Select your favorite providers

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3. Compare prices and book

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 76 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Round-trip from	$454 (Copa Airlines)
One-way from	$258 (Copa Airlines)
Popular in	April
Cheapest in	August
Average price	$863

From Santiago Arturo Merino Benitez to San Diego

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One-way flight from Santiago Arturo Merino Benitez to San Diego

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Highest demand for flights based on searches. 15% potential increase in price ($164 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($30 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2025.

Tue 8/1212:13 amSCL - SAN

1 stop20h 31mCopa Airlines

Wed 8/209:03 pmSAN - SCL

1 stop19h 21mCopa Airlines

Deal found 7/6

$454

Wed 8/274:11 amSCL - SAN

1 stop16h 33mMultiple Airlines

Sun 8/319:00 amSAN - SCL

2 stops40h 15mMultiple Airlines

Deal found 7/8

$672

Sun 8/2410:45 pmSCL - SAN

1 stop22h 32mLATAM Airlines

Fri 9/56:20 amSAN - SCL

2 stops20h 05mLATAM Airlines

Deal found 7/8

$678

Wed 8/138:40 pmSCL - SAN

1 stop15h 57mDelta

Tue 8/1910:47 amSAN - SCL

1 stop17h 13mDelta

Deal found 7/8

$687

Tue 7/299:50 pmSCL - SAN

2 stops19h 40mAmerican Airlines

Tue 9/306:15 amSAN - SCL

2 stops21h 40mAmerican Airlines

Deal found 7/7

$703

Best flights from Santiago to San Diego
Discover carefully curated flight deals from Santiago to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2025.

Tue 8/1212:13 amSCL - SAN

1 stop20h 31mCopa Airlines

Wed 8/209:03 pmSAN - SCL

1 stop19h 21mCopa Airlines

Deal found 7/6

$454

Wed 8/274:11 amSCL - SAN

1 stop16h 33mMultiple Airlines

Sun 8/319:00 amSAN - SCL

2 stops40h 15mMultiple Airlines

Deal found 7/8

$672

Sun 8/2410:45 pmSCL - SAN

1 stop22h 32mLATAM Airlines

Fri 9/56:20 amSAN - SCL

2 stops20h 05mLATAM Airlines

Deal found 7/8

$678

Wed 8/138:40 pmSCL - SAN

1 stop15h 57mDelta

Mon 8/1812:09 pmSAN - SCL

1 stop15h 51mDelta

Deal found 7/8

$687

Tue 7/299:50 pmSCL - SAN

2 stops19h 40mAmerican Airlines

Tue 9/306:15 amSAN - SCL

2 stops21h 40mAmerican Airlines

Deal found 7/7

$703

Last-minute flights from Santiago to San Diego
Discover last-minute flight deals from Santiago to San Diego. Data last updated July 8, 2025 and is based on user searches.

Tue 7/299:50 pmSCL - SAN

2 stops19h 40mAmerican Airlines

Tue 9/306:15 amSAN - SCL

2 stops21h 40mAmerican Airlines

Deal found 7/7

$703

Tue 8/1212:13 amSCL - SAN

1 stop20h 31mCopa Airlines

Wed 8/209:03 pmSAN - SCL

1 stop19h 21mCopa Airlines

Deal found 7/6

$454

Wed 8/138:40 pmSCL - SAN

1 stop15h 57mDelta

Mon 8/1812:09 pmSAN - SCL

1 stop15h 51mDelta

Deal found 7/8

$687

Sun 8/2410:45 pmSCL - SAN

1 stop22h 32mLATAM Airlines

Fri 9/56:20 amSAN - SCL

2 stops20h 05mLATAM Airlines

Deal found 7/8

$678

Wed 8/274:11 amSCL - SAN

1 stop16h 33mMultiple Airlines

Sun 8/319:00 amSAN - SCL

2 stops40h 15mMultiple Airlines

Deal found 7/8

$672

One-way flights from Santiago to San Diego
Search for one-way flight options from Santiago to San Diego. Find affordable one-way fares based on user searches. Data last updated July 8, 2025.

Thu 8/2812:24 amSCL - SAN

1 stop20h 20mCopa Airlines

Deal found 7/6

$258

Mon 11/312:45 amSCL - SAN

2 stops24h 18mMultiple Airlines

Deal found 7/7

$380

Mon 11/311:40 pmSCL - SAN

1 stop29h 01mDelta

Deal found 7/7

$573

Thu 12/1810:45 pmSCL - SAN

1 stop19h 42mUnited Airlines

Deal found 7/6

$581

Sat 11/18:55 pmSCL - SAN

1 stop19h 23mAir Canada

Deal found 7/7

$590

Thu 11/2012:30 amSCL - SAN

2 stops24h 20mLATAM Airlines

Deal found 7/7

$604

Sun 1/411:15 pmSCL - SAN

1 stop21h 39mAmerican Airlines

Deal found 7/6

$1,214

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 8/12

12:13 am-5:44 pm

1 stop20h 31m

San Diego

Wed 8/20

9:03 pm-7:24 pm

1 stop19h 21m

$454

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 8/27

4:11 am-5:44 pm

1 stop16h 33m

San Diego

Sun 8/31

9:00 am-4:15 am

2 stops40h 15m

$672

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sun 8/24

10:45 pm-6:17 pm

1 stop22h 32m

San Diego

Fri 9/5

6:20 am-5:25 am

2 stops20h 05m

$678

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 8/13

8:40 pm-9:37 am

1 stop15h 57m

San Diego

Tue 8/19

10:47 am-7:00 am

1 stop17h 13m

$687

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 7/29

9:50 pm-2:30 pm

2 stops19h 40m

San Diego

Tue 9/30

6:15 am-7:55 am

2 stops21h 40m

$703

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 8/28

12:24 am-5:44 pm

1 stop20h 20m

$258

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 11/3

12:45 am-8:03 pm

2 stops24h 18m

$380

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 11/3

11:40 pm-11:41 pm

1 stop29h 01m

$573

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/1

8:55 pm-12:18 pm

1 stop19h 23m

$590

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 11/20

12:30 am-7:50 pm

2 stops24h 20m

$604

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/6

Showing 1-10 of 12 results

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta

8.0

Very good

7,958 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

LATAM Airlines

7.5

Good

1,807 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Copa Airlines

7.5

Good

1,472 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines

7.4

Good

8,844 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,958 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

What are the cheapest airlines flying from Santiago to San Diego round-trip?
Our cheapest airline available from Santiago to San Diego is Copa Airlines. Our recent data shows that you can find tickets from as low as $454 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $678 and $687 round-trip. Copa Airlines is currently priced 50% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Santiago to San Diego one-way?
To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $258. Delta flights start at $573 while deals on United Airlines start at $581 one-way.
Can I find deals for flights from Santiago to San Diego that include hotel bookings?
Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to San Diego?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.
Can I find deals for business class flights from Santiago to San Diego?
Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to San Diego?
Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to San Diego

Top 2 airlines flying from Santiago to San Diego

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$702	Average$853	FlexibilityNo cancel fee	On-timeN/A
LATAM Airlines	Cheapest$803	Average$933	FlexibilityNo cancel fee	On-time81%

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$258+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago to San Diego with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 76 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San DiegoExplore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2025.

Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Diego. Price data was last updated on June 27, 2025.

What is the cheapest month to book a flight from Santiago to San Diego?

Reviews of airlines servicing San Diego

Get a feel of what it's like to fly with Delta, LATAM Airlines, and Copa Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santiago to San Diego round-trip?

What are the cheapest airlines to fly from Santiago to San Diego one-way?

Can I find deals for flights from Santiago to San Diego that include hotel bookings?

How can I find direct flights from Santiago to San Diego?

Can I find deals for business class flights from Santiago to San Diego?

What is the cheapest month to book a flight from Santiago to San Diego?

Traveling to a place near Santiago?

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Alternative routes for Santiago to San Diego

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Top 2 airlines flying from Santiago to San Diego

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Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2025.